CURRICULUM VITAE I. BASIC INFORMATION Surname Name Affiliation Address Phone - office Phone - mobile Fax e-mails Web page Zugic Ana Institute of Medicinal Plant Research “Dr Josif Pancic”, Belgrade. Tadeusa Koscuska 1, 11 000 Belgrade, R. Serbia. +381/11 30 31 658 +381/64 867 49 11 +381/11 30 31 655 azugic@mocbilja.rs http://www.mocbilja.rs II. ACADEMIC RECORDS Professional experience 2008-onwards Institute of Medicinal Plant Research "Dr Josif Pancic", Belgrade, R. Serbia. Department for Pharmaceutical R&D. Progress in Higher Education & Professional Specialisation 2008 Master of Science in Pharmacy University of Belgrade, Faculty of Pharmacy, Belgrade, R. Serbia. Title ”Formulation and physical stability tests of emulsion carriers with alkyl polyglucoside emulsifier-Montanov™82” 2009-onwards Ph.D. studies in Pharmaceutical Technology University of Belgrade, Faculty of Pharmacy Belgrade, R. Serbia. 1 Progress in Research position 2010-onwards 2008-2010 Research Assistant Institute of Medicinal Plant Research “Dr J. Pancic”, Belgrade, R. Serbia Research Trainee Institute of Medicinal Plant Research “Dr J. Pancic”, Belgrade, R. Serbia Current duties 2010-onwards Research Assistant in Department for Pharmaceutical R&D, Institute of Medicinal Plant Research "Dr Josif Pancic", Belgrade, R. Serbia. Main research areas - Pharmaceutical technology Pharmacognosy Industrial pharmacy Cosmetology Key research qualifications Knowledge and experince in following research areas: - Optimization of formulation and production process (physic-chemical and in vitro/ in vivo characterization) of pharmaceutical/cosmetic preparations with plant isolates as active/cosmetically active substances - Reformulation of pharmaceutical/cosmetic preparations - Chemical analysis of plant isolates as active ingredients in pharmaceutical preparations - Chemical analysis of medicinal and aromatic plants (UV-VIS spectrophotometry, High Performance Liquid Chromatography, (HPLC)) - Making of normative–technical documentation Current research interests - Emulsions (dermopharmaceuticals) stabilized with lamellar mesophase as vehicles for isolates of natural origin as active ingredients for the topical treatment of skin infections (physico-chemical and in vitro/ in vitro characterization, liberation profile, skin bioengineering techiques) - Formulation and process optimization of different pharmaceutical forms (lozenge, capsules, solutions, creams) with functional and physiologically active plant materials with added value Current engagement in national scientific projects 2011-onwards Research Assistant Project III 45017, financed by Ministry of education, science and technological development Project title: " Functional physiologically active plant materials with additional value for usage in pharmaceutical and food industry" Project leader: Prof. Dr. Irena Zizovic, Faculty of Technology and Metallurgy, University of Belgrade 2 2011-onwards Research Assistant Project III 41030, financed by Ministry of education, science and technological development Project title: “Biological effects, nutritional intake and status of folate and polyunsaturated fatty acids: The improvement of nutrition in Serbia " Project leader: Dr Marija Glibetic, Center of Excellence in Nutrition and Metabolism Research, CENM, Institute for Medical Research, Belgrade Engagements in already completed Scientific Project (last ten year period) 2009-2010 Research Trainee Project TR 20137, financed by Ministry of education, science and technological development Project title: "The modern concept of the usage of natural medicinal agents (mineral water, medicinal peloide, medicinal plants) of Vrujci Spa." Project leader: Dr sc Vanja Tadic, Department for Pharmaceutical R&D, Institute of Medicinal Plant Research "Dr Josif Pancic", Belgrade. III. ADDITIONAL ACADEMIC RECORDS Language skills English, grade A (Careers Abroad language Center- CALC Certificate), German, CEF A 2.2 (Berlitz School) Membership in scientific and professional associations 2010-onwards Gesellschaft für Arzneipflanzenforschung (Society for Medicinal Plant Research), Germany 2012-onwards Association de Pharmacie Galénique Industrielle (International Society of Drug Delivery Sciences and Technology), France Other professional engagements 2009 Organization of a visit and a lecture about Institute for Medicinal Plant Research “Dr Josif Pančić” activities to foreign students as a part of an interactive workshop “Fusion of Knowledge regarding Medicinal Plants – Collaboration between Young Pharmacists, Agronomists and Foresters” in cooperation with Belgrade Pharmacy Students Association (a member of European Pharmacy Students Association and International Pharmaceutical Students’ Federation) 3 IV. SCIENTIFIC PUBLICATIONS (last 10 year period) International Scientific Journals (SCI list) Arsic I, Zugic A, Runjajic Antic D, Zdunic G, Dekanski D, Markovic G, Tadic V, (2010): „Hypericum Perforatum L. Hypericaceae/Guttiferae Sunflower, Olive and Palm Oil Еxtracts Attenuate Cold Restraint Stress – Induced Gastric Lesions“, Molecules, vol. 15 (10): 6688-6698. Arsic I., Zugic A, Tadic V, Tasic-Kostov M, Misic D, Primorac M, Runjajic Antic D (2012): “Estimation of Dermatological Application of Creams with St. John’s Wort Oil Extracts“, Molecules, vol. 17(1): 275-294. Zugic A, Djordjevic S, Arsic I, Markovic G, Zivkovic J, Jovanovic S, Tadic V (2014): “Antioxidant activity and phenolic compounds in 10 selected herbs from Vrujci Spa, Serbia”, Ind Crop Prod, vol. 52: 519–527. Arsić IA, Tadić VM, Đorđević SM, Žugić AR, Vujić ZB, Petrović SD, (2014): “Optimization of extraction of antioxidant components from Yarrow herb”, Hem Ind, vol. 68 (4):511-517. Žugić AR , Lukić MZ,. Tasić Kostov MZ, Tadić VM, Arsic IA, Mišić DR, Petrović SD, Savić SD, (2015): „Alkyl polyglucoside-stabilized emulsion as a prospective vehicle for Usnea barbata CO2 supercritical extract: assessing stability, safety and efficiency of a topical formulation”, Hem Ind, (in press); doi: 10.2298/HEMIND140701002Z. Zugic A, Lunter DJ, Daniels R, Pantelic I, Tasic Kostov M, Tadic V, Misic D, Arsic I, Savic S, (2015): “Usnea barbata CO2-supercritical extract in alkyl polyglucoside-based emulsion systems: Contribution of Confocal Raman imaging to the formulation development of a natural product”, Pharm Dev Technol, (in press); doi: 10.3109/10837450.2015.1026606). International Conferences (Proceedigs) Tadic V, Runjajic-Antic D, Arsic I, Đorđevic S, Jovanovic S, Markovic G, Zugic A, Zivkovic J (2010): “Plant extracts implementation in mineral mud originated from spa Vrujci”. 6th CMAPSEEC, Conference on Medicinal and Aromatic Plants of Southeast European Countries, 18-22th April, Antalya. Pharmacognosy Magazine, pg 230. Arsic I, Zugic A, Runjaic- Antic D, Zdunic G ,Dekanski D, Markovic G, Tadic V (2010): “Gastroprotective activity of Hypericum perforatum extracts prepared with different vegetable oils”. 58th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 29 thAugust – 2nd September, Berlin. Planta Medica, pg 12. Markovic GM, Tadic VM, Arsic IA, Đorđevic SM, Zugic AR (2010): HPLC determination of quercetin-type flavonoids, vitexin and chlorogenic acid in hawthorn raw material and pharmaceutical preparations. 58th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, 29 thAugust – 2nd September, Berlin. Planta Medica, pg 12. Arsic I, Zugic A, Tadic V, Djordjevic S, Runjaic-Antic D (2011): “Application of design of experiments in the improvement of Achillea millefolium solvent extraction using Timatic micro extractor”. 5th International Congress on Pharmaceutical Engineering, 29-30th September, Graz. ICPE Book of Abstracts, pg 75. Tasic-Kostov M, Pavlovic D, Lukic M, Zugic A, Savic S (2012): “Emulsions based on alkyl polyglucoside surfactants with lactobionic acid: physicochemical characterization and in vitro antioxidant activity”. Skin and Formulation 4th Symposium, 4-5th June, Lyon. Book of abstracts, pg 66. Zugic A, Tasic-Kostov M, Arsic I, Misic D, Tadic V (2012): „Topical effects and antimicrobial 4 activity of the O/W creams with St. John's wort oil extracts”. Skin and Formulation 4th Symposium, 4-5th June, Lyon. Book of abstracts, pg 100. Arsic I, Zugic A, Tadic V, Đorđevic S (2012): “Application of solvent-enhanced extraction for obtaining Achillea millefolium extract with potential usage in food industry”. CEFood, 6th Central European Congress on Food, 23-26th May, Novi Sad. Abstract book, pg 127. Zugic RA, Tadic MV, Bojovic RD, Arsic AI, Đorđevic MS, Stamenic DM (2012): “Impact of extraction method on chemical composition of Sideritis scardica Griseb., Lamiacae extracts”. 7th CMAPSEEC, Conference on Medicinal and Aromatic Plants of Southeast European Countries, 27-31th May, Subotica. Book of Abstracts, pg 59. Zugic RA, Tadic MV, Bojovic RD, Arsic AI, Đorđevic MS, Aksentijevic TK, Stamenic DM (2012): “Antimicrobial activity of supercriticaln and conventional extracts of Sideritis scardica Griseb., Lamiacae”. 7th CMAPSEEC, Conference on Medicinal and Aromatic Plants of Southeast European Countries, 27-31th May, Subotica. Book of Abstracts, pg 93. Arsic I, Tadic V, Đorđevic S, Zugic A, Pavkov S (2013): “Antioxidant properties of Aronia juice”. 1st International Congress on Hygiene and Preventive Medicine, Serbian Medical Society, 22-24th May, Belgrade. Book of Abstracts, pg 123-125. Tadić V, Arsić I, Dekanski D, Tošić J, Isaković A, Djordjevic S, Žugić A (2013) “Investigation of Aronia melanocarpa fruit juice application as gastroprotective agent”. 17th International Congress Phytopharm, 8-10th July. Veinna. Abstract Book, pg 93. Tadic V, Djordjevic S, Zugic A, Arsic I, Bogdanovic A, Homsek I (2013): “Sensitive HPLC Method for the Determination of Usnic Acid in Tablets“. 5th International BBBB Conference, 26th-28th September, Athens. Eur J Pharm Sci 50, Supplement 1, PP142, pg 117. Zugic A, Tadic V, Lunter DJ, Daniels R, Pantelic I, Arsic I, Savic S (2014): “Usnea barbata L. supercritical extract in APG-based emulsion system: Considerations of colloidal structure using Raman spectral imaging“. 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 31th March-3rd April, Lisbon. CD-ROM. Tasić-Kostov M, Bogdanović-Marković D, Žugić A, Lukić M, Savić S (2014): “Physicochemical and in vivo assessment of topical emulsions stabilized with novel non-ionic emulsifier of natural origin”. 9th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 31th March-3rd April, Lisbon. CD-ROM. Žugić AR, Tasić-Kostov MZ, Naumović SS, Arsić IA, Tadić VM, Đorđević SM, Savić SD (2014): “Estimation of dermatological application of creams with CO2--supercritical extract of Usnea barbata L., Usneaceae”. 8th CMAPSEEC, Conference on Medicinal and Aromatic Plants of Southeast European Countries, 19-22th May, Durres. Book of Abstracts, pg 127. Žugić AR, Tadić VM, Pantelić IN, Arsić IA, Đorđević SM, Savić SD (2014): “Assessment of preliminary chemical stability of a cream containing CO2-Supercritical extract of Usnea barbata L., Usneaceae”. 8th CMAPSEEC, Conference on Medicinal and Aromatic Plants of Southeast European Countries, 19-22th May, Durres. Book of Abstracts, pg 128. Žugić AR, Tadić VM, Arsić IA, Đorđević SM, Mišić DR, Savić SD (2014): “CO2-supercritical extract of Usnea barbata L., Usneaceae in a topical formulation: evaluation of antimicrobial activity”. 8th CMAPSEEC, Conference on Medicinal and Aromatic Plants of Southeast European Countries, 19-22th May, Durres. Book of Abstracts, pg 129. International scientific books-book chapter Tadić V, Žugić A, Arsić I (2014): „Multi-target herbal preparations“ In Roj E (Eds.) „Supercritical CO2 extractions“, Polish Foundations of the Opportunities Industralization Centers „OIC Poland“, Lublin, pp. 99-121. 5 National Scientific Journals Arsic I, Đorđevic S, Tadic V, Runjaic-Antic D, Marković G, Pavkov S, Zugic A (2009): “Comparative characterization of blackberry leaf extracts”, Matieres medicales, vol. 29:51-61. Zugic A, Đorđević S, Tadić V, Arsic I, Misic D (2013): “Antimicrobial activities of elecapane root isolates”, Advanced Technologies, vol. 2(2): 33-40. National Conferences (Proceedigs) Žugić A, Đorđević S, Tadić V, Arsić I, Mišić D, (2013): „Antimikrobna aktivnost izolata omana“, X Simpozijum “Savremene tehnologije i privredni razvoj” sa međunarodnim učešćem, 22. – 23. oktobar, Leskovac. Zbornik izvoda radova, str. 79. Arsić I, Tadić V, Đorđević S, Žugić A, Mišić D, (2013): „Mikrobiološka aktivnost ekstrakata kleke (Juniperus comunis L.) i sremuša (Allium ursinum L.)“, X Simpozijum “Savremene tehnologije i privredni razvoj” sa međunarodnim učešćem, 22. – 23. oktobar, Leskovac. Zbornik izvoda radova, str. 80. A. Žugić, M. Tasić-Kostov, S. Naumović, I. Arsić, V. Tadić, D. Mišić, S. Savić, (2014): „Usnea barbata CO2 natkritični ekstrakt u emulziji stabilizovanoj alkil poliglukozidnim emulgatorima: procena efikasnosti i bezbednosti“, VI KONGRES FARMACEUTA SRBIJE sa međunarodnim učešćem, 15.-19. oktobar, Beograd. Zbornik sažetaka, str. 147 (oral presentation). V. PROFESSIONAL PUBLICATIONS Books, manuals and other professional publications in Serbian Đorđevic S, Dickov A, Pavkov S, Tadic V, Arsic I, Zugic A (2013): “Manufacturing process of high quality phytopreparation on example of herbal sedative”, Medical review, vol. 66 (3-4): 170176. VI. AWARDS International awards 2012 Grant awarded by German Academic Exchange Service (ger. DAAD Deutscher Akademischer Austauschdienst) for the research stay at Institut für Pharmazeutische Technologie, Eberhard-Karls Universität, Tübingen, Germany 6