Bovine Johne’s Disease (BJD) NT Fact Sheet last updated: 17 December 2012 What is Johne’s Disease Johne's disease (JD) is a serious wasting disease of cattle, sheep, goats, alpaca, llama, camels and deer caused by the bacteria Mycobacterium avium paratuberculosis. Despite a normal appetite, an animal suffering from JD develops can develop chronic diarrhoea or ill thrift, leading to a gradual loss of bodyweight, emaciation and eventually death. All animals showing signs of disease will inevitably die. There is no treatment. In Australia, BJD predominantly occurs in areas of the southern states, and particularly in dairy cattle herds. It is less common in beef herds. There is a cattle strain - bovine Johne’s disease (BJD) which affects all of the above species except sheep, and a sheep strain - ovine Johne’s disease (OJD) which affects sheep. How is it spread The bacteria may be found in the faeces of infected animals. Young animals are most susceptible to infection by ingestion of M paratuberculosis either when suckling their dam or grazing contaminated pasture. The bacteria survive in faecal material and on pastures where other animals can pick up the infection. In damp conditions, bacteria can survive in the environment for up to a year. The bacteria invade the lining of the small intestine and lymph nodes. The disease develops very slowly and very few animals test positive to the disease until they are adults. Unfortunately, in the meantime they can be shedding the bacteria in their faeces, possibly infecting other animals. In infected animals not displaying symptoms of disease, the shedding of the bacteria may be delayed and intermittent. Healthy carrier animals with no signs of disease can shed the bacteria but it is also possible that infected animals may not be shedding bacteria at all times. This means testing for the disease is very difficult. How is it controlled The National Johne's Disease Control Program (NJDCP) aims to help livestock industries to reduce the spread and impact of Johne's disease in Australia. Key components of the NJDCP are the Standard Definitions, Rules and Guidelines (SDR&Gs) for different BJD zones and areas, movement controls between zones and areas and official disease control programs. The following link will provide more information on Johne’s Disease http://www.animalhealthaustralia.com.au/programs/jd/jd_home.cfm Northern Territory has a “Protected” status for BJD and is regarded by the rest of Australia as having a very low prevalence of BJD, only being detected when infected animals are introduced from interstate. To maintain this status Northern Territory has a policy of eradication of the disease if it is suspected or shown to be present in a herd. BJD has been introduced into Northern Territory herds following importation of infected animals from interstate on three occasions in 1976, 1994 and 2001 and was successfully eradicated from each herd with no further spread within the herd or to other herds. DEPARTMENT OF PRIMARY INDUSTRY AND FISHERIES Diagnosis Blood samples: Blood can be collected from live animals to test for Johne’s disease. Results from a blood test are rapid but inappropriate for the assessment of individual animals as false positives and negatives can occur. This test is less reliable than others for the true status of the animal. Faecal culture: Samples from the faeces are taken in an attempt to grow the bacteria the laboratory. This test provides a reliable result however if the animal is not shedding bacteria at the time the faeces is collected (due to early stage of disease or intermittent shedding) the result can be inaccurate. A follow-up sample is needed for negative test results. Tissue culture: Samples from a range of animal tissues, including the intestines and associated lymph nodes, are taken in an attempt to grow the bacteria in a laboratory setting. This test is the definitive test however can only be taken once the animal has been destroyed. Culture tests take up to 14 weeks to complete. Histological examination: Samples of tissue collected at post mortem are examined microscopically. This test is specific and sensitive. However, the test is only available after the animal has been destroyed. The definitive test for JD is tissue culture. Where to from here Your Regional Livestock Biosecurity Officer will work with you to formulate a management plan. All activities must be consistent with the national BJD SDR&Gs and the Livestock Act. Your property will remain with a suspect status for BJD until the status of all suspect animals has been satisfactorily resolved. The definitive result is ordinarily by tissue culture. Options for dealing with Suspect animals 1. Destroy the animal and obtain samples for histological examination and tissue culture. Results available within 12-14 weeks. This will require the animal to be slaughtered and sampled on-property. 2. Isolate the animal from the herd and hold the live animal segregated for 6 months until test results are available. Blood and faeces are collected from the live animal for ELISA and faecal culture tests. A second faecal sample is collected 12 weeks after the first sample if test results are negative to provide evidence that the animal is not shedding bacteria in the faeces. 3. Retain the animal in the herd long term. Whilst the animal remains alive and its status remains unresolved, the status of companion animals cannot be resolved. It also increases the risk of potential spread of disease. This will mean the property will remain with a suspect status for BJD until a definitive test result can be obtained. Department of Primary Industry and Fisheries pays for the testing costs of these animals. There is no compensation available for the destruction of these animals. If the animal can’t be located on the property, a sample of the herd will need to be tested to provide evidence that BJD has not been spread to other in-contact animals. www.nt.gov.au/d/animalhealth © Northern Territory Government Page 2 of 3 Property The status of the property can only be resolved when a valid risk assessment and investigation is complete. This will include identifying: the infected and infective status of the introduced bulls through laboratory testing how long the animal has been on the property what contact the animal may have had with other animals on the property what class, type and age of other animals it may have had contact with. and possibly a herd testing program Until this risk assessment can be completed satisfactorily, your property will remain with a suspect status for BJD and movement restrictions will apply. The objective of movement restrictions is to protect susceptible livestock, market access and NT livestock industry from the adverse impacts of further spread of disease. For more information For more information on BJD, please contact NT BJD Co-ordinator Sue Fitzpatrick Email: susanne.fitzpatrick@nt.gov.au Ph: 08 8999 2123 | Fax: 08 8999 2146 Mob: 0407 498 003 Postal: GPO Box 3000, Darwin NT 0801 Website: www.nt.gov.au/d/animalhealth Disclaimer: While all care has been taken to ensure that information contained in this document is true and correct at the time of publication, the Northern Territory of Australia gives no warranty or assurance, and makes no representation as to the accuracy of any information or advice contained in this publication, or that it is suitable for your intended use. No serious, business or investment decisions should be made in reliance on this information without obtaining independent and/or professional advice in relation to your particular situation. www.nt.gov.au/d/animalhealth © Northern Territory Government Page 3 of 3