“NJSH 2014 Spring Meeting”
Sponsored by Poly Scientific R&D Corp
and Sakura Finetek USA
WHEN: Saturday, April 5
WHERE: Double Tree Suites by Hilton
515 Fellowship Road North, Mount Laurel, NJ 08054
AGENDA
7:30-8:30 AM Check-In, Networking and Continental Breakfast
8:30-10:00 AM Seminar #1 Respiratory Histopathology
10:00-10:30 AM Coffee Break
10:30-12:00 PM Seminar #2 Pathology of the Urinary Tract
12:00-1:00 PM Buffet Lunch
1:00-2:30 PM Seminar #3 Animal Model Development to Aid in the Understanding
of Human Atherosclerosis
2:30-3:00 PM Goodie Break
3:00-4:30 PM Seminar #4 Predictive Testing in Non-small Cell Lung Cancer: Testing
Protocols, Specimen Requirements and Near Future Techniques, Notably Next
Generation Sequencing
Seminar Abstracts
Respiratory Histopathology
Donna G. Chuddley, BS, CLA, HT (ASCP)
Divisional Manager, Huntingdon Life Sciences, East Millstone, NJ
This presentation will focus on the recovery of specialized respiratory tissues during
necropsy and subsequent histopathology processing according to the RITA guidelines.
There will be in-depth descriptions of the gross anatomy and microscopic structures of
the tissues (e.g., nasal turbinates, pharynx, larynx, lungs and lymph nodes) in both small
and large animals. Photomicrographs of normal tissues, technical artifacts, and pathology
findings will be displayed. This knowledge will enhance the ability to deliver quality
slides with well represented target tissues that have historically brought challenges to the
histopathology laboratory. Some questions that will be addressed are: 1) Why do we fill
the lungs differently at necropsy; 2) How many levels of tissue are really required for
trimming; and 3) What are the pathologist's requirements concerning these target
tissues? At the conclusion of this presentation, attendees will have a better understanding
of respiratory anatomy and the underlying reasons for the careful handling of these
delicate tissues.
Pathology of the Urinary Tract
David E. Rubin, MD, FCAP
Department of Pathology, Good Samaritan Hospital, Suffern NY
Juan Rosai, currently one of the most famous pathologists living today, wrote a
monograph on the history of surgical pathology for the AFIP called Guiding the
Surgeon’s Hand. If his equivalent in the field of Histology were to write a monograph on
the history of histology, the title might be called Guiding the Pathologist’s Eyes. This
lecture will concentrate on the organs making up the urinary tract and their immediate
attachments: Kidney, Ureter, Bladder, Prostate, Urethra. Following relatively brief
descriptions of the normal function for each organ, the discussion will then shift to
discuss those diseases that result in biopsies or resections of these organs, the types of
specimens likely to result from these surgical procedures, the types of sections ending up
in tissue cassettes, and what special requests may follow the traditional H&E slides. The
overarching goal of this lecture is to give the histologist insight into how and what the
pathologist is thinking in his or her approach to a case, just as the pathologist can do his
or her work better by having insight into what the patient’s clinicians are thinking and
how they are approaching that case.
Animal Model Development to Aid in the Understanding of Human Atherosclerosis
Linda Watson, BS
Department of Discovery Toxicology, Bristol-Myers Squibb, Princeton NJ
Atherosclerosis is a complex and chronic disease with an inflammatory component that
contributes to the underlying cause of most cardiovascular illness and is a leading cause
of death throughout the modern world. Often without the individual’s knowledge, the
progression and cellular changes occur over decades before an acute symptom of
cardiovascular disease presents itself. The aim and goal of this presentation is to convey
an understanding of human lesions and the various cellular and structural changes that
occur during lesion development observed in animal models, and how lesion
development in the two species may overlap. Currently, there are no non-invasive tests to
determine the stage of the lesion with regards to human disease and the clinician relies
heavily on plasma lipoproteins levels, family history of cardiovascular disease, and life
style choices. Therefore, treatment options tend to target lowering of Low Density
Lipoproteins (LDLs) with the addition of consuming a low fat diet combined with
exercise. This course of treatment does not address the cellular wall component of the
various stages of the lesion due to the nature of the disease and the limitations clinicians
and research scientists have in studying the disease in real time. The development and
availability of various animal models have allowed for greater awareness of
atherosclerosis. Even though there is not one perfect model and various models have their
advantages and disadvantages, these models have improved our understanding of the
mechanism of lesion progression leading to increased options for treatment.
Predictive Testing in Non-small Cell Lung Cancer: Testing Protocols, Specimen
Requirements and Near Future Techniques, Notably Next Generation Sequencing
Bruce C. Horten, MD, Medical Director - NY, Integrated Oncology, LabCorp Speciality
Testing Group
Abstract was not available at time of printing.
COST:
$90 All attendees will receive a free renewal* or new NJSH membership!
$45 for Students (must present current Student ID card at check-in)
*Note to previous NJSH members: ALL memberships expired May 31, 2013.
REGISTRATION INFORMATION:
Space is limited, so Pre-Registration is REQUIRED!
Mail the form below with a check made payable to the NJSH by March 15th to:
NJSH Meeting Registration, P.O. Box 6792, Lawrenceville, NJ 08648
OR register and pay online by visiting the website http://njsh.org/njsh/
Please note that a $1.00 fee will be added to on-line transactions.
E-mail questions to michele.french@bms.com
NSH members will be eligible for 6 CEUs.
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