CES Research Symposium Presentation Descriptions 8:40am: Tanju Karanfil and Jessica Economy – Meeting Room A Title: Presentation of new CES Post-Doctoral Support Office Description: The College of Engineering and Science is pleased to announce that a new post-doctoral support office is in process of being established. The office will be designed to offer services to scholars and departments to help improve the post-doc experience for all. The presentation will introduce the office to the college as well as present information regarding the benefits of the office to all audiences, services offered, and timeline of the project. *According to Dr. Karanfil, this presentation should be set up to be seen by majority of attendees, whether through time or through multiple presentations 8:50am: Lisa Benson – Meeting Room A Title: Student Motivation and Learning in Engineering Description: The focus of my research portfolio is on identifying factors that contribute to students’ motivation to pursue engineering as a major, and to correlate these motivational attributes to problem-solving and knowledge transfer. Understanding these relationships will address one of the greatest challenges facing engineering educators: preparing students for a future of complex problem solving in the face of rapid technological change and globalization. My research group has collected and analyzed both quantitative (survey) and qualitative (interview and focus groups) data from students in bioengineering, mechanical engineering, and materials science and engineering; this allows for comparisons between disciplines with overlapping content and skill sets but different student demographics and career goals. Quantitative results showed subtle differences between student motivations in different majors, and indicated the need to explore motivation factors more deeply. ! Qualitative results are revealing differences in students’ perceived future possible selves, which affect their perceptions of the relevance of present activities and how they approach solving a problem in a context that is novel to them. 9:00am: Amod Ogale – Meeting Room A Title: CAEFF Perspective: Advanced Fibers and Films Research Description: Center for Advanced Engineering Fibers and Films (CAEFF), a self-sustaining graduated NSF-ERC, continues to provide an interdisciplinary research environment for the systems-oriented study of high performance fibers, films, and composites for applications ranging from military to medical uses. CAEFF was established in 1998-99 and received $ 29 million dollars from NSF over the maximum 10-year funding cycle. Faculty and students from six academic departments (ChE, MSE, Chemistry, Math, ME, and BioE) continue to conduct research involving about twenty sponsored projects with annual expenditures of over $ 2 million. The broad topics include: fibers for high-strength, thermal/electrical conductivity, and composites; fiber-based bio-medical devices; fibers/films for separation/filtration; and modeling (FiSim, Polyflow, and MD). Custom-designed test-beds and potential opportunities for collaboration, viz. advanced carbon fibers/composites and micro-textured films, will be discussed. 9:10am: Apparao Rao – Meeting Room A Title: Research at Clemson Nanomaterials Center Description: Materials at the nanoscale (~10 -9 m) exhibit unique properties and novel behavior different from their bulk counter parts. In this talk, a brief overview of synthesis, characterization and applications of nanomaterials ranging from impact protection, batteries and supercapacitors, thermoelectrics, superconductors, nanoelectronics, optical diodes, sensors, nanomedicine and oil spill removal will be presented. Particularly, we will discuss how Clemson Nanomaterials Center (CNC) is addressing our current and impending global energy needs through the development of efficient lighting, superconductors, and high-power high-energy hybrid capacitors for use in nearly all sectors of interest, from transportation to communications and intermittent energy sources. Besides synthesizing and promoting applications of nanomaterials at the CNC, we also elucidate their fundamental properties using a wide range of spectroscopic tools such as micro-Raman, Fourier Transform Infrar! ed, UV-visible, nonlinear optical, and photoluminescence spectroscopy. The nanomaterials covered in this talk include 0D (quantum dots), 1D (rods, wire, coils and tubes) and 2D (graphene, bismuth telluride) materials. 9:20am: Thompson Mefford – Meeting Room A Title: A Versatile Stable Platform for Multifunctional Applications using Iron Oxide Nanoparticles Description: Magnetic nanoparticles have been studied for many years for use in biomedicine, not only for their high surface area, but also because of its unique magnetic properties. They can magnetically interact with their environment, be guided to a specific location, and manipulated to release energy in the form of heat. To ensure that these magnetic nanoparticles survive in the circulatory system, they must be modified with materials to make them colloidally stable in water and shield them from the body’s immune response to foreign objects. This presentation will describe the synthesis of a multi-anchored universal ligand for iron oxide nanoparticles, with improved stability in biological environments, while also providing a platform for additional functionality. What will be presented represents the initial findings of the research opportunities available with this new platform for diagnostic and therapeutic applications. 10:00am: Ken Marcus – Meeting Room A Title: Miniaturized Spectroscopic Sources for Elemental and Isotopic Analysis Description: Current commercial analytical instrumentation for elemental and isotopic analysis primarily exists on laboratory-based platforms, requiring large quantities of power, large volumes of sample (and waste), and large volumes of support gases. We have developed atomic emission and mass spectrometry devices which move the genre into much smaller scales of operation, without commensurate sacrifices in performance. Reductions in size allow for wider implementation in the laboratory, and also for field-deployable formats. For example, current funding from DTRA and DOE are directed at applications in the nuclear nonproliferation arena. Use of the devices in environmental and industrial monitoring applications are also envisioned. 10:00am: Raj Bordia – Meeting Room B Title: Ceramics for Energy Applications: Control of Hierarchical Microstructure Description: Our current research is focused on developing processing strategies to control the microstructure of ceramics at different length scales. Although the projects are diverse, they all share common features including integration of mechanics in processing, and coupled theory, simulations and experimental investigations. In this presentation, a few examples from our current work on ceramic systems for energy applications will be highlighted. Most of these applications demand optimization of a multitude of properties many of which have conflicting requirements on the microstructure. Materials with designed anisotropic and hierarchical microstructures have the potential to optimally address these conflicting requirements. 10:10am: Brian Powell – Meeting Room A Title: The use of radioisotope tracers to support studies of environmental contaminants: Making the most of Clemson's broad scope radioactive materials license Description: Radioisotope tracers have been widely employed in science and technology applications to yield ultra-sensitive and high resolution measurements of ions in various media. In this talk, examples of ongoing work will be shown in which radiotracers have been used to monitor 1) subsurface migration of dissolved contaminants and nanoparticles 2) ligand exchange on nanoparticle surfaces, 3)properties of the electrical double layer at mineral-water interfaces, and 4) plant uptake of radioisotopes and herbicides. Clemson University has a broad scope license to safely hold, handle, and dispose of a broad range of radioisotopes and we have a significant amount of instrumentation to support this work. The goal of this presentation is to seek out collaborators who are interested in employing radioisotope tracer studies in their own work. 10:10am George Chumanov – Meeting Room B Title: Nanostructures for materials, energy and analytical applications. Description: We synthesize, modify and assembly various nanoparticles (NPs) into 1D,2D and 3D structures as well as nanopcomposites. One focus is on silver plasmonic particles for photovoltaic devices. Silver NPs were also used for optical labeling for bioanalytical applications. Another example is antimicrobial properties of copper halide NPs. In addition to synthetic capabilities our expertize includes Raman including surface-enhanced Raman scattering spectroscopy and atomic force microscopy. 10:20am: Mark Blenner – Meeting Room A Title: Engineering Microorganisms for the Sustainable Production of Chemicals Description: The Blenner research group works on a variety of projects involving the production of chemicals through protein and metabolic engineering of microbial metabolism. Our work currently revolves around the development of novel genetic engineering tools for a yeast platform best suited for oleochemicals and acids production. We are currently working processes for bioproduction of dicarboxylic acids, omega-3 fatty acids and renewable fuels. We are actively seeking collaborators who have ideas for chemicals that we could produce, or highperformance applications resulting from bioproduced polymer building blocks. 10:20am Luiz Jacobson – Meeting Room B Title: New Materials for Radiation Measurement: Microstructure, Defects and Luminescence Description: Ionizing radiation is found in nature and man-made materials and activities. Its measurement is of extreme relevance in many strategic fields, including energy, security, health, and technology in general. My research program aims at the discovery and development of new materials for the detection and measurement of ionizing radiation. It focuses on the synthesis of new materials, from nanoparticles to nanocomposites and transparent ceramics, and the understanding of the relations between microstructure, defects, dopants, and luminescence taking advantage of optical spectroscopy techniques. 10:30am Yi Zheng – Meeting Room A Title: Enzymatic catalysis for biofuels and bioproducts Description: Enzyme is an important biocatalyst being present in every bioprocess. It plays a critical role in the bioconversion of biomass into biofuel and bioproduct. Enzymatic catalysis is preferred over chemical catalysis because its conditions are much milder and it is potentially more energy efficient and friendly for process control. However, low catalysis efficiency and high cost of enzymes prevent the broad applications of enzymes in biorefinery for biofuels and bioproducts. Therefore, development of high-efficient enzymes and high-value applications of enzymes should be addressed. 10:30am Molly Kennedy – Meeting Room B Title: Wear of Whitened Enamels Due to Restorative Material Sliding Contact Description: Despite remarkable improvement in the nation's oral health over the years, record numbers of restorative procedures to repair damaged enamel and dentin are being performed. Unlike bone, dental mineralized tissue has no mechanism for repair after damage and synthetic materials are often used to repair the damage to the enamel by coating the enamel, filling holes in the enamel/dentin or replacing the entire tooth structure. Damage to enamel can be caused by wear due to attrition (tooth-to-tooth sliding), abrasion (sliding of abrasives such as tooth paste or hard objects) and corrosion (due to acidic fluids coming into contact with enamel or dentin). To better understand the extent to which external factors may influence enamel degradation, many groups have focused developing characterization methods to determine both the wear mechanisms and rates of homogenous (regular) enamel. 10:40am Christophe Darnault – Meeting Room A Title: Detection and Transport of Cryptosporidium parvum in the Subsurface Environment Description: Understanding the behavior of pathogenic microorganisms (e.g., Cryptosporidium parvum oocysts) in the environment is critical for the protection of the environment and public health. To characterize the transport and retention processes of these bio-particles in porous media, we have investigated their mobility under different hydrodynamic and chemical conditions found in the natural environment. We have established the role of vadose zone processes and surfactant on the transport of C. parvum oocysts in soils. To quantify these bio-particles, as well as to elucidate the individual contribution of the mechanisms and environmental parameters affecting their transport and retention, we have developed monitoring methods and tools using physical, chemical, microbiological, and molecular technologies. The results of our research will contribute to the development and validation of fate and transport models of contaminants from pore scale to watershed scale for sustai! nable water resources management, and risk assessment. 10:40am Fei Peng – Meeting Room B Title: Processing and properties of ceramic-based composites Description: The ceramic-based composites enable additional new sets of functionality beyond the traditional ceramic materials. They have unique electrical, magnetic, and optical properties, which make them suitable for a variety of innovative applications. These applications include protection and shielding, electric and magnetic field sensing, and non-linear optic generation. Our research is focused on understanding the processing sciences of such materials with engineered microstructure, and correlating the desired properties with the processing and microstruture. We are especially interested in low dimensional ceramic-based composites such as fibers and coatings because of their versatility in different application situations. 10:50am Tanju Karanfil – Meeting Room A Title: Carbonaceous Adsorbents for and in Environmental Applications Description: I will discuss the research in my group on carbonaceous adsorbents (activated carbons, carbon fibers, carbon nanotubes and graphenes) in and for environmental applications. On one side we may benefit from some of these adsorbents for engineered treatment systems. On the other side, if a material is produced in large quantities, it will eventually enter environment creating various problems. Therefore, understanding adsorption by the carbonaceous adsorbents can be helpful on how to manipulate and benefit from these materials and/or reduce their impact in environment. The presentation will also aim to provide a perspective to those developing materials and especially for environmental applications. Finally, I will briefly summarize the research and instrument capabilities of my labs. 10:50am Hongseok Choi – Meeting Room B Title: Scale-up manufacturing of bulk metal matrix nanocomposites Description: Incorporation of nanomaterials into various structural materials can produce significantly enhanced chemical, physical, and mechanical properties. However, the difficulty for a uniform dispersion of the nanomaterials and their structural integrity in the matrix is still a prominent obstacle to use the intrinsic properties of the nanocomposites to the full extent, and a lack of fundamental understanding of the interactions of the nanomaterials with liquid and solid matrices severely hinders the advancement of scale-up manufacturing of nanocomposites. The fundamental knowledge about the interactions of nanomaterials with the matrix during manufacturing processes is promising for the flexible design of bulk nanocomposites with desirable properties. This talk will discuss about various scientific and technological aspects that are critical for scale-up manufacturing of nanocomposites, particularly focused on high performance lightweight metal matrix nanocomposites (! MMNCs). Scientific issues relevant to dispersion, distribution, and stability of nanoparticles in molten metals will be discussed to realize more widespread applications of the MMNCs through a science-based transformative manufacturing process. 11:00am John Saylor – Meeting Room A Title: Drops and Bubbles Description: The set of problems that exist at a gas/liquid interface is rich and finds numerous applications. Our research focuses on a specific set of these problems, namely the air/water interface of drops and bubbles. In this brief talk I will discuss some of our recent research in this area which includes drop/particle interactions, ultrasonic manipulation of bubbles and drops, drop splashes, raindrop imaging, and others. Applications include particulate pollution control, carbon dioxide sequestration, evaporation control, and reduced water use in the generation of electrical power. 11:00am Modi Wetzler – Meeting Room B Title: Molecular control over polymer architecture Description: We can synthesize nearly perfectly monodisperse polyamide polymers (N-substituted polyglycines) with molecular weights of 5K-20K with precise positioning of a wide variety of side chains. As a demonstration we synthesized a decablock 120mer with aliphatic, aromatic, and ether-functionalized blocks. We are interested in exploring new potential applications for such polymers and/or using them as test cases for fundamental polymer physics questions. 11:10am Brian Powell – Meeting Room A Title: Energetics of ion interactions at mineral-water interfaces Description: Adsorption to mineral surfaces is one of the primary means of limiting the migration of contaminants in the subsurface and the extent of sorption can be drastically altered by chemical, physical, and biological processes. Due to this inherent complexity, field scale models predicting the transport of contaminants frequently use empirical methods to incorporate sorption which leads to non-transferable models and overly conservative assumptions. In this work, we are examining ion interactions with surfaces to characterize the fundamental thermochemical reactions and driving forces. The primary tools are x-ray absorption spectroscopy, isothermal titration calorimetry, electron microscopy, and radiotracer experiments. These data are used to constrain a detailed thermochemical model of ion sorption to mineral surfaces. A more detailed understanding of these processes will improve reactive transport models examining the impact of contaminant disposition on human and environmental health. 11:10am Srikath Pilla – Meeting Room B Title: Engineered Methodologies for Sustainable Design and Fabrication of Biorenewable Composites and Foams Description: Legislation that mandates higher fuel efficiency, environmental sustainability and lower carbon emissions without compromising on safety and strength is necessitating lightweight construction, especially in the automotive sector. It is a well-known realization that the drastic lightweighting in the automotive sector meeting the aforementioned strength and safety could be achieved by adopting sustainable multi-functional composite materials and foams. In this regard, this research focusses on developing engineered methodologies for the design and fabrication of biorenewable composites and foams. 11:20am John Sanders – Meeting Room A Title: Thermal Performance of Masonry Materials Description: We are investigating the non-steady state thermal performance of clay brick masonry. Energy codes and current DOE software typically rely on indicators, like R-value, that are measured under steady state conditions. The dynamic thermal performance of clay brick masonry, which includes the benefits of thermal mass, have not been well understood. We are developing the systems needed to measure the dynamic thermal performance of clay brick masonry which will let us understand existing systems and design more energy efficient building systems. 11:20am Steve Creager – Meeting Room B Title: Electrochemical energy conversion and storage Description: I will present a brief description of funded projects relating to electrode and electrolyte materials for low-temperature hydrogen fuel cells. Materials to be discussed will include fluoropolymer electrolytes for proton and hydroxide ion conduction and composite electrodes having mixed electronic and ionic conduction. The talk will emphasize recently completed work and areas where I think collaboration could be useful. Possibilities for more wide-ranging extensions, including biological (e.g. microbial) and high-temperature (e.g. solid-oxide) electrochemical cells will also be discussed. 11:30am Lindsay Shuller-Nickles – Meeting Room A Title: Using electrochemistry to understand reactions at mineral surfaces Description: The transport of aqueous contaminants is impacted by sorption and reduction on mineral surfaces; however, the exact role of the mineral surface remains elusive. We use cyclic voltammetry with a powder mineral electrode to probe changes in uranyl redox kinetics on Feoxide and Fe-sulfide minerals as compared with a traditional Pt microelectrode and Pt powder microelectrode. In addition, this technique has been used to evaluate doped-semiconducting mineral samples in order to compare the redox of uranium in different coordination environments. We are currently looking for collaborations to develop techniques to image the surface either microscopically or spectroscopically to determine the geometry of the sorbed uranium. 11:30am Sapna Sarupria – Meeting Room B Title: Using Molecular Simulations to Study Water, Aqueous Systems, Polymers and Proteins Description: Molecular modeling and computer simulations provide powerful tools to study material properties at the molecular level in detail. In our research, we use molecular dynamics simulations combined with several advanced sampling techniques to study water and aqueous systems. We study a range of different problems including effects of surfaces on ice formation, transition of liquid methane-water systems to solid crystalline methane hydrates, assembly of virus capsids, and structure and behavior of dendritic polymers in water. We are particularly interested in using simulations to provide insights towards engineering advanced materials (polymer and biological) with desired properties. 11:40am Lindsay Shuller-Nickles – Meeting Room A Title: The interface of in silico and experimental techniques: Using quantum-mechanical calculations to clarify, guide, and complement experiments Description: With the advancement of parallel computing, quantum-mechanical calculations of larger (tens of atoms) systems can now be used to better understand atomic and electronic scale phenomena that control processes such as contaminant sorption and reduction on a mineral surface or charge-compensated incorporation of an impurity into a crystalline system. Such calculations are useful for gaining insight into the mechanisms that control complex systems. With this computational looking glass, researchers can collaborate in a range of fields from chemical separations of specific resources (e.g., U) to environmental remediation of contaminants. 11:40am Chad Sosolik – Meeting Room B Title: CUEBIT: A User Facility for Probing Highly Charged Ion-Materials Interactions Description: A new electron beam ion trap (EBIT) based ion source and beamline were recently commissioned at Clemson University to produce decelerated beams of multi- to highly-charged ions for surface and materials physics research. Our user facility is the first installation of a DREEBIT-designed superconducting trap and ion source (EBIS-SC) in the U.S. and includes custom-designed target preparation and irradiation setups. The unique physics of this oneof-a-kind radiation source will be discussed and put into the context of new experimental systems and conditions that can be explored. This will include a call for materials collaborators with expertise in both surface and bulk analysis of their targets. Additionally, the current status of theory and modeling will be outlined, listing the current challenges for combined computational-experimental studies in this field. 11:50am Rachel Getman – Meeting Room A Title: Molecular Simulations of Metals, Metal Oxides, and Metal-Organic Frameworks for Photocatalytic Splitting of Water and/or Carbon Dioxide Reduction Description: We are using density functional theory (DFT), Monte Carlo (MC), and other computational techniques to design catalyst materials. At this time, the project of interest is in the white paper phase. We are presently designing catalysts for photocatalytic splitting of water; however, we may shift focus to photocatalytic carbon dioxide reduction (or something else) in the future. In general, we are seeking collaborators with expertise in experimental or computational photochemistry. We can offer a vast expertise in molecular-level modeling to the collaboration. Our group uses quantum chemistry, Monte Carlo, molecular dynamics, as well as thermodynamic and kinetic modeling, to elucidate molecular level phenomena at fluid/solid interfaces. We have the capability to model systems comprising up to 100 heavy metal atoms or up to 1000 light atoms (and more and more as the Palmetto cluster continues to expand). 11:50am Mark Blenner – Meeting Room B Title: Protein Engineering for Bioactive and Bioresponsive Materials Description: The Blenner research group is seeking new ideas and collaborators interested in either whole biomolecular materials or incorporating bioactive proteins and peptides into non-biological materials. Our research group is a protein engineering group that focuses on improving the properties of natural biomolecules through genetic and molecular level manipulation. The role of proteins in self-assembly of nano-scaled structures is of interest, as is the incorportation of proteins that endow the nano-scaled system with bio-responsive properties. We can provide protein and peptide expertise to a varierty of projects. 1:00pm Mark Thies – Meeting Room A Title: Ultrapure Lignin of Controllable Molecular Weight as a Renewable Biopolymer: A Wide Range of Applications? Description: Lignin is unique among renewable biopolymers in having significant aromatic character, which makes it attractive as a "green" replacement for its synthetic, petroleum-derived counterparts. Recently, Thies and co-workers have discovered processing techniques for purifying and fractionating Kraft lignins derived from papermill waste streams. In recent preliminary experiments, the key metals content of a Kraft lignin was reduced by more than two orders of magnitude down to 80 ppm in two simple steps, well under the 150 ppm level found in lignin produced from trees via the costly organic-solvent pulping (called “Organosolv”) processes. Furthermore, the feed Kraft lignin was simultaneously fractionated during the metals removal step into low and high molecular weight (mol wt) fractions. We thus hypothesize that the above unique, multifunctional process can be used to produce clean lignins of controlled molecular weight for a wide range of applications. One of! those could be the conversion of an appropriate ultrapure lignin fraction into inexpensive carbon fibers suitable for automotive applications. 1:00pm Hugo Sanabria – Meeting Room B Title: Proteins at work -one molecule at a time Description: The intrinsic relationship between structure, dynamics, and function of biomolecules is well recognized but poorly understood. We developed a fluorescence-based toolkit to study, over 10 decades in time, the structure, dynamics and function of biomolecules. As benchmark study we studied the Lysozyme of the bacteriophage T4. We reproduced two known crystallographic structures with accuracy < 2.1 Ã…. In addition, we resolved a new product release state predicted by the Michaelis-Menten formalism in Enzyme kinetics. 1:10pm Amin Khademi – Meeting Room A Title: Applications of Operations Research Description: A discipline that deals with the application of advanced analytical methods to help make better decisions. It is used in many applications such as supply chain management, scheduling, and transportation. I am interested in the application of operations research in health care, data mining and energy. 1:10pm Ken Marcus – Meeting Room B Title: Capillary-Channeled Polymer (C-CP) Fiber for Downstream Processing of Protein Therapeutics and Protein Analytics/Diagnostics Description: Polymer stationary phases have been developed for affecting protein separations on the preparative and analytical scales. C-CP fibers are practically commodity items, which have excellent solution and solute mass transport properties in column formats. Chemical selectivity can be affected by the nature of the base polymer or through straightforward surface modification chemistries. Current NSF funding supports efforts rapid protein chromatography and selective protein extraction. Implementation on industrial scales and in diagnostic/assay formats is readily envisioned. 1:20pm Scott Husson – Meeting Room A Title: Water-Energy Consortium at Clemson Description: My presentation will summarize the activities of the Water-Energy Consortium (WEC), which has been established at Clemson to organize and coordinate research activities addressing the water-energy nexus. The nexus between water and energy involves energy aspects of water systems and water aspects of energy systems. Five WEC research themes have been suggested: 1. Innovative, energy-efficient water/wastewater purification processes and systems 2. Materials science in water-energy nexus applications 3. Water resources and hydrologic systems: monitoring, sensors, and modeling 4. Improved water efficiency of energy resource development and production systems 5. Water management implications of the water-energy nexus The vision of the WEC is to promote global recognition of Clemson University as being at the forefront of research addressing the water-energy nexus. The mission of the WEC is to contribute research leading to technology innovations in water systems with a minimization of energy and carbon footprints, as well as energy systems with a minimization of water and carbon footprints. 1:20pm Mark Blenner – Meeting Room B Title: Engineering Highly Specific Protein-Ligand Interactions Description: The Blenner research group is working to develop new methods for engineering highly specific protein-ligand interactions. Overall, we are fairly agnostic about the applications of this technology - since it should be a broadly applicable solution useful for numerous applications. We are currently considering applications in biosensing, metabolic engineering, and therapeutics - and are seeking collaborators to help us identify problems in need of better and cheaper biosensors, as well as therapeutic applications where specific protein-ligand interactions will improve diagnosis and patient outcomes. Furthermore, environmental applications are also under consideration. 1:30pm Nigel Kaye – Meeting Room A Title: Mixing in stratified flows Description: Mixing in stratified flows has many applications in environmental fluid mechanics including dense gas dispersion, mixing in estuaries, and air flows in buildings. This presentation will focus on the flushing of a dense fluid confined in a cavity with a flow over the open top of the cavity. The rate of flushing is initially controlled by the flow Richardson number and there is an exponential decay in the cavity concentration. For high Richardson numbers a two layer stratification is established whereas for lower Richardson numbers the cavity remains well mixed. In later stages of the flushing, it is influenced by the turbulence intensity of the over flowing fluid. 1:30pm Feng Ding – Meeting Room B Title: Structure, dynamics, and function of biomolecules and molecular complexes Description: We apply concepts and methods in Physics, especially Statistical Physics, to study biological systems. The major theme throughout our research is to integrate dynamics into the study of structure-function relationship of biomolecules and molecular complexes. Our lab focuses both on methodology developments as well as applications on particular biologically-oriented problems. The methodologies include rapidly dynamics sampling algorithms, multiscale models and force fields for biomolecules, and tools for protein engineering and protein design. Currently, we are applying these methods to study interactions between nanomaterials and biomolecules, engineering proteins to bind specific small molecule targets, and the molecular mechanism of specificities in post-translational modifications. 1:40pm David Ladner – Meeting Room A Title: Computational fluid dynamics (CFD) modeling of novel spacers used for reverse osmosis desalination Description: Water purification with reverse osmosis (RO) is inherently energy intensive. The problem is exacerbated when salts build up on the membrane surface. This project seeks to design spacers that minimize the salt buildup. CFD modeling is used to test various designs and experiments are performed to validate the models. Some novel spacer geometries have shown promise for decreasing the energy intensity of RO and many options remain for future testing. 1:40pm Julia Brumaghim – Meeting Room B Title: Understanding Antioxidant Prevention of Metal-Mediated DNA Damage Description: Antioxidants have great potential to prevent neurodegenerative and cardiovascular diseases, diabetes, cancer, and aging that are all caused by metal-mediated DNA damage. Although typical studies of antioxidant activity focus on scavenging damaging reactive oxygen species, we have quantified and compared the abilities of widely-studied sulfur, selenium, and polyphenol antioxidants to inhibit metal-mediated DNA damage and found that metal binding, not radical scavenging, is the primary mechanism for their DNA damage prevention activity. All three classes of antioxidants prevent DNA damage by coordinating the iron and copper ions responsible for hydroxyl radical generation. From these studies, we have developed the first predictive models for polyphenol DNA damage and cell death prevention based on iron binding that will aid in development of antioxidant supplements and therapies. 1:50pm Margaret Wiecek – Meeting Room A Title: Mathematical Optimization for Decision Making in Engineering and Sciences Description: Mathematics-based optimization provides tools to model and solve decision making problems that are associated with systems in engineering and sciences. A man-made system may involve interactions among many phenomena and require reconciling various engineering disciplines. It may have multiple and dissimilar levels or components that may be connected in a variety of ways and as a whole exhibit one or more properties not obvious from the properties of the individual parts. A complex system may also be characterized by noncomparable and conflicting requirements, interactions, and objectives (e.g., cost, performance, reliability, safety, productivity, affordability). Optimization models and algorithms address the system complexity and encompass decision makers' judgments and preferences to derive an optimal or preferred decisions, designs, or policies. 1:50pm Andy Tennyson – Meeting Room B Title: Organometallic Complexes to Prevent Inflammation and Immune Activation Description: A diverse array of pathologies, ranging from the side effects of radiation therapy to transplant rejection, arise from immune system activation in response to localized inflammation. Increasing superoxide dismutase expression levels or treating with tocopherols, thiols or omega-3 fatty acids are effective therapies for alleviating these conditions, collectively suggesting that oxidative stress plays a central role in the onset of inflammation. Based on these findings, we have established a program to prepare transition metal complexes that reduce oxidative stress and, by doing so, exert anti-inflammatory effects. Our preliminary studies have demonstrated that the targeted organometallic complexes catalytically degrade radicals in buffered aqueous solutions. 2:00pm Taufiquar Khan – Meeting Room A Title: Modeling and Parameter Estimation Description: We will discuss the general approach for modeling and parameter estimation in applications. We will discuss examples of collaboration across the college. In particular we will discuss a range of applications from car following theory in smart transportation to modeling complex network in smart grid to imaging in biomedical applications. 2:00pm Pingshan Wang – Meeting Room B Title: Microwave microsystems Description: Microwave microsystems, i.e. microwave lab-on-chip, are very promising for label-free detection and identification of single cells, particles and molecules. They are expected to find wide applications in personalized health service, environment monitoring, and advanced analytic instrumentation for chemical, biological and material studies. In this talk, I will present our results on the development of microwave microsystems, including high-sensitivity measurements of DNA molecules in solutions, paramagnetic samples and gases. 2:10pm Ilya Safro – Meeting Room A Title: Efficient and Effective Methods in Network Science, Scientific Computing, and Optimization Description: Effective, fast, and scalable mathematical methods and models serve as a common basis for many complex systems in natural sciences, and engineering. My research interests include such methods for large-scale data. They can be categorized as multiscale methods, machine learning, data mining, networks and graph algorithms, data analysis, predictive modeling, optimization. 2:10pm Hai Xiao – Meeting Room B Title: Photonic and Microwave Sensors, Instrumentation and Imaging Description: This presentation provides a general introduction to the Photonics Technology Laboratory (PTL) recently moved to Clemson University. We conduct research in 1) novel sensor, devices and systems, 2) ultrafast laser micro-/nano-machining, 3) integration of nanomaterials with photonic/microwave devices for chemical sensing, and 4) bio-sensing and optical medical imaging. We look forward to establishing collaborative research within Clemson in areas of affordable energy, sustainable environment, intelligent infrastructure, health care, and national security. 2:20pm Xin Liu – Meeting Room A Title: Stochastic Processes and Their Applications Description: I am interested in stochastic processes, mathematical statistics and their applications. One main area of interest is the study of queueing systems. I am currently working on the queueing modeling of limit order books. Another ongoing project is on multiscale diffusion approximations for SIR models with vectors. 2:20pm Jeff Anker – Meeting Room B Title: Multifunctional Luminescent Sensors Description: My group develops novel spectrochemical imaging techniques and contrast agents to study chemical and biomechanical processes through tissue. One project involves developing sensors to be coated on the surface of fracture fixation devices to image pH and other analytes during infection and inflammation. A second project involves measuring mechanical strain on implanted devices through tissue. A third project involves measuring making magnetic fluorescent sensors to track single particle intracellular rotational transport in macrophage cell cultures and measure viscosity through tissue. A fourth project involves developing multifunctional nanoparticles for magnetically guided drug delivery, MRI contrast, upconversion luminescence, and radioluminescence. 3:20pm Gerald Lehmacher – Meeting Room A Title: Aeronomy Experiments for Reusable Suborbital Launch Vehicles Description: NASA is supportive of private enterprises that are in the process of developing launch capabilities for suborbital and orbital spacecraft. Researchers around the world are curious whether multiple launches of reusable spacecraft can advance aeronomy research, especially in the mesosphere and lower thermosphere, where observations are scarce and difficult. I am involved in several collaborative proposal efforts to develop neutral wind and temperature measurements for such future missions and monitor the reentry dynamics. Techniques include micro-g accelerometers, pressure gauges, and free-flying, inflatable spheres. For quantitative results, detailed modeling of supersonic flow in rarefied atmospheres is necessary. 3:20pm Bill Pennington – Meeting Room B Title: Polydiacetylene-based Sensors Description: Polydiacetylenes (PDAs) are conjugated polymers that exhibit interesting chromic behavior, and are useful for a variety of sensing applications, such as for temperature, mechanical impact, and detection of biological entities. The visible signals exhibited by PDA sensors make them preferential to other sensor technologies for many applications, particularly within the food industry. Diacetylene monomers have been incorporated into or onto a variety of substrates to serve as colorimetric strain and temperature sensitive films and fibers. PDAs functionalized with amino acids, sugars or other recognition elements exhibit a colorimetric response in the presence of bacteria, toxins, etc. Potential applications, problems and areas for collaboration will be discussed. 3:30pm Andrej Ivanco – Meeting Room A Title: System Level Analysis of the Vehicle Powertrain Description: The 2025 CAFE standards mandates 54.5MPG average fuel economy for new vehicles to be sold in the US market. Achieving it will require development of the new approaches for powertrain component design, vehicle power management and understanding of the consumer drive cycles all from the perspective of system level control and optimization. Some recent research highlights will be presented to foster the collaborative spirit within the faculty. 3:30pm Guigen Zhang – Meeting Room B Title: Toward Personalized and Preventive Care Description: To make personalized and preventive care possible, it is necessary to have highly accurate, affordable and fast diagnostic tool capability to screen possible genetic disorders, detect diseases at an early stage, and even monitor gene mutation regularly. The biosensing technology we are pursuing has the potential to make it a reality. 3:40pm Simona Onori – Meeting Room A Title: Model-based battery management system Description: With more stringent regulations on emissions and fuel economy, global warming, and constraints on energy resources, electrified vehicles have attracted more and more attention by automakers, governments, and customers. One of the key constraints for mass market penetration of this vehicle technology is the high cost of the battery system, as well as the safety and reliability concerns associated with it. The tasks to ensure safe and reliable operation of the battery system, extend the life of battery, and maximize driving range are demanded to battery management systems (BMS). Properly designing BMSs for electrified vehicles can help optimize the system efficiency and reduce cost while extending battery system life expectancy and increasing safety of the battery system. 3:40pm Rodrigo Martinez-Duarte – Meeting Room B Title: Multiscale Manufacturing Laboratory: Research Partners wanted Description: The Multiscale Manufacturing Laboratory (M2L) is looking for research partners. We have a strong expertise on glass-like carbon microfabrication, microfluidics and Dielectrophoresis. Current research areas include: 1) Clinical Diagnostics, using centrifugal microfluidics, electrokinetics and biosensors; 2) Carbon-based composites departing from polymer-based composites; 3) Bio-enabled nanomanufacturing, using microorganisms to fabricate nanostructures; and 4) Diagnosis of Chagas disease in a rural setting. 3:50pm David Smith – Meeting Room A Title: The Creative Car Lab: An Interaction Design Studio for Future Vehicle Concepts Description: The Creative Car lab on the he CU-ICAR campus is a new, unique facility for multi-disciplinary collaboration on user experience design of vehicles of the future. Emphasis is placed on concept development for the cockpit, building on societal and technological trends to create new interactive experiences. Research projects lie at the intersection of automotive engineering, human-centered computing, media design, and art. 4:00pm John Ballato – Meeting Room A Title: Opportunities for research using optical fibers at Clemson Description: Clemson is the only University in the United States, and one of only a few in the world, with industry-grade capabilities to make optical fiber. This brief talk will highlight the fabrication capabilities and showcase the types of fibers made and sponsored programs awarded in this topical area. 4:00pm Endre Takacs – Meeting Room B Title: X-ray experiments at the Clemson University Electron Beam Ion Trap (CUEBIT) Description: The new CUEBIT facility at the Department of Physics and Astronomy is unique device for creating highly charged ions. These exotic atomic systems miss most of their electron clouds and can only be created in several million degree hot plasmas. The interactions of the ions with solid surfaces or with the energetic electron beam of the device generate x-rays with special properties. 4:10pm Julie Martin – Meeting Room A Title: Social factors influencing the recruitment, retention, and career development of engineering students Description: This presentation describes work relating to social factors influencing the recruitment, retention, and career development of engineering students. One goal for the presentation is to increase awareness of ongoing basic research in the field of engineering education. In particular, the presenter will discuss a mixed methods research project funded by her NSF CAREER award relating undergraduate students’ social capital and their decisions to enter and persist in engineering. {Please note the this presentation does not fit within one of the CU Research Emphasis areas} 4:10pm Kim Alexander – Meeting Room B Title: Collaboration in Sponsored Projects for Research and Innovation in Road Safety Description: The Institute for Global Road Safety and Security (IGRSS) is an interdisciplinary research community dedicated to improving road safety and security through a systemic analysis of the human-vehicle-road system. The Institute brings together nationally and internationally recognized researchers, educators, and government and corporate partners to pursue sponsored research in order to improve the safety of the automotive transportation environment. A key focus area for IGRSS is in development and implementation of innovative road safety research and education programs including K-12 programs, college programs, driver training, military safe driver training, workforce development and leadership training, commercial motor carrier safety education, occupant protection and child passenger safety, pedestrian and bike safety issues, accommodation education, and substance abuse prevention education. One way the institute is able to collaborate with other departments, cen! ters, and institutes is by providing educational research and outreach activities for grants and contracts. IGRSS, the Government of Kenyan, and Maasai Mara University are partnering to provide road safety research, education, policy support, and outreach in Kenya. 4:20pm Kuang-Ching Wang – Meeting Room A Title: Center for Next Generation Computing - Rethink what IT means to your research Description: The Center for Next Generation Computing is approved by Board of Trustee in 2013 as a center point for collaboration among faculty and CCIT on the use and development of advanced computing and networking infrastructure for research and education in the university. The Center collaborates with faculty in developing and executing sponsored research projects as well as in informing the roadmap of university cyberinfrastructure. The Center is in active collaboration with faculty across colleges on multiple projects in areas such as advanced computing, software defined networking, cyber security, big data, visualization, GIS, etc. One of the latest project transforms the university network and Palmetto Cluster to connect to campus and external research facilities and data archives over 10G~100G bps networks. We will provide an overview of these activities and explore new collaboration opportunities with the faculty.