Recent publications (2007 – 2013)
G. Ruberto, A. Renda, C. Daquino, V. Amico, C. Spatafora, C. Tringali, N. De Tommasi
Polyphenol constituents and antioxidant activity of grape pomace extracts from five Sicilian red grape cultivars
Food. Chem., 100, 203-210 (2007)
S. Grasso, L. Siracusa, C. Spatafora, M. Renis, C. Tringali.
Hydroxytyrosol lipophylic analogues: enzymatic synthesis, radical scavenging activity and DNA damage protection.
Bioorg. Chem., 35, 137-152 (2007)
M. G. Sarpietro, C. Spatafora, C. Tringali, D.Micieli, F. Castelli
Interaction of resveratrol and its trimethyl and triacetyl derivatives with biomembrane models studied by Differential
Scanning Calorimetry.
J. Agric. Food Chem 55, 3720-3728 (2007)
R. Chillemi, S. Sciuto, C. Spatafora, C. Tringali
Anti-tumor Properties of Stilbene-based Resveratrol Analogues: Recent Results
Nat. Prod. Comm., 2, 499-513 (2007)
V. Cardile, R. Chillemi, L. Lombardo, S. Sciuto, C. Spatafora, C. Tringali
Antiproliferative activity of methylated analogues of E- and Z-resveratrol.
Z. Naturforsch. 62 c, 189 - 195 (2007)
C. Spatafora, C. Tringali
Phenolic oxidative coupling in the biomimetic synthesis of heterocyclic lignans, neolignans an related compounds, in
‘Targets in Heterocyclic System. Chemistry and Properties’ Vol. 11. D. Spinelli and O. A. Attanasi (Eds), Società
Chimica Italiana, Rome, Italy (2007) pp. 284-312.
G. Ruberto, A. Renda, V. Amico, C. Tringali,
Volatile components of grape pomaces from different cultivars of Sicilian Vitis vinifera L.
Biores. Technol., 99, 260–268 (2008)
V. Amico, R. Chillemi, S. Mangiafico, C. Spatafora, C. Tringali
Polyphenol-enriched fractions from Sicilian grape pomace: HPLC-DAD analysis and antioxidant activity
Biores. Technol. 99, 5960-5966 (2008)
V. Amico, V. Barresi, R. Chillemi, D. F. Condorelli, S. Sciuto, C. Spatafora, C. Tringali
Bioassay-guided isolation of antiproliferative compounds from grape (Vitis vinifera) stems
Nat. Prod. Comm., 4, 27-34 (2009)
C. Spatafora, G. Basini, L. Baioni, F. Grasselli, A. Sofia, C. Tringali
Antiangiogenic resveratrol analogues by mild m-CPBA aromatic hydroxylation of 3,5-dimethoxystilbenes
Nat. Prod. Comm., 4, 239-246 (2009)
K. Svechnikov, C. Spatafora, I. Svechnikova, C. Tringali, O. Söder
Effects of resveratrol analogues on steroidogenesis and mitochondrial function in rat Leydig cells in vitro
J. Appl. Toxicol. 29, 673-680 (2009)
C. Daquino, A. Rescifina, C. Spatafora, C. Tringali
Biomimetic Synthesis of Natural and “Unnatural” Lignans by Oxidative Coupling of Caffeic Esters
Eur. J. Org. Chem., 6289-6300 (2009)
H.-S. Lin, C. Tringali, C. Spatafora, C. Wu, P. C. Ho
A simple and sensitive HPLC-UV method for the quantification of piceatannol analog trans-3,5,3’,4’tetramethoxystilbene in rat plasma and its application for a pre-clinical pharmacokinetic study
J. Pharm. Biomed. Anal. 51, 679-684 (2010)
R. Chillemi, S. Sciuto, C. Spatafora, C. Tringali
Hydroxytyrosol lipohilic analogues: synthesis, radical scavenging activity and human cell oxidative damage protection
in ‘Olives and Olive Oil in Health and Disease Prevention’ V. R. Preedy and R. R. Watson Eds, Oxford, Academic
Press, 1233-1243 (2010)
F. Mazué, D. Colin, J. Gobbo, M. Wegner, A. Rescifina, C. Spatafora, D. Fasseur, D. Delmas, P. Meunier, C. Tringali,
N. Latruffe
Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new
analogs.
European Journal of Medicinal Chemistry 45, 2972-2980 (2010)
G. Basini, C. Tringali, L. Baioni, S. Bussolati, C. Spatafora, F. Grasselli
Biological effects on granulosa cells of hydroxylated and methylated resveratrol analogues
Molecular Nutrition and Food Research, 54, S236-S243 (2010)
H.-S. Lin, C. Tringali, C. Spatafora, Q.-Y. Choo, P.C. Ho
LC Determination of trans-3,5,3',4',5'-Pentamethoxystilbene in Rat Plasma
Chromatographia, 72, 827-832 (2010)
G. Malfa, B. Tomasello, C. Spatafora, V. Cardile, C. Scifo, C. Tringali, M. Renis
Chemotherapeutic effects of resveratrol and its analogue 3,5,4'-trans-trimethoxystilbene on DU145 cells
Trends in Cancer Research, 6, 45-54 (2010)
H.-S. Lin, W. Zhang, M. L. Go, C. Tringali, C. Spatafora, P.C. Ho
Quantification of trans-3,4,5,4'-Tetramethoxystilbene in Rat Plasma by HPLC: Application to Pharmacokinetic Study.
Journal of Agricultural and Food Chemistry 59, 1072-1077, (2011).
S. Di Micco, C. Daquino, C. Spatafora, F. Mazué, D. Delmas, N. Latruffe, C. Tringali, R. Riccio, G. Bifulco
Structural basis for the potential antitumour activity of DNA-interacting Benzo[kl]xanthene lignans
Organic & Biomolecular Chemistry 9, 701-710 (2011)
C. Tringali
Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug
Discovery, C. Tringali Ed., CRC Press/Taylor & Francis Group, Boca Raton. (2012). ISBN 978-1-4398-2229-6
C. Spatafora, C. Tringali
From Natural Polyphenols to Synthetic Antitumor Agents, in: Bioactive Compounds from Natural Sources, Second
Edition: Natural Products as Lead Compounds in Drug Discovery, C. Tringali Ed., CRC Press/Taylor & Francis
Group, Boca Raton, pp 299-338, (2012). ISBN 978-1-4398-2229-6
N. Latruffe, D. Delmas, G. Lizard, C. Tringali, C. Spatafora, D. Vervandier-Fasseur, P. Meunier
Resveratrol against major pathologies: from diet prevention to possible alternative chemotherapies with new structural
analogues in: Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in
Drug Discovery, C. Tringali Ed., CRC Press/Taylor & Francis Group, Boca Raton. pp 339-378, (2012). ISBN 978-14398-2229-6
H.-S. Lin, C. Spatafora, C. Tringali, P.C. Ho
Determination of trans-2,4,3',4',5'-pentamethoxystilbene in rat plasma and its application to pharmacokinetic study.
Journal of Pharmaceutical and Biomedical Analysis 57, 94-98 (2012)
G. Basini, L. Baioni, S. Bussolati, F. Grasselli, C. Daquino, C. Spatafora, C. Tringali
Antiangiogenic properties of an unusual benzo[k,l]xanthene lignan derived from CAPE (Caffeic Acid Phenethyl Ester)
Investigational New Drugs 30, 186-190 (2012)
C. Spatafora, C. Tringali
Valorization of vegetable waste: identification of bioactive compounds and their chemo-enzymatic optimization
The Open Agriculture Journal, 6, 9-16, (2012)
G. Valdameri, L. R. Pereira, C. Spatafora, J. Guitton, C. Gauthier, O. Arnaud, A. Pereira Ferreira, P. Falson, S. M. B.
Winnischofer, M. E. M. Rocha, C. Tringali, A. Di Pietro
Structure-activity relationships of methoxy stilbenes: potent, specific, not transported and not cytotoxic inhibitors of
breast cancer resistance protein.
ACS Chemical Biology, 7, 322-330 (2012)
C. Spatafora, C. Tringali
Natural-derived Polyphenols as Potential Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry, 12, 902-918 (2012)
V. M. Bhusainahalli, C. Spatafora, M. Chalal, D. Vervandier-Fasseur, P. Meunier, N. Latruffe, C Tringali
Resveratrol-related Dehydrodimers: Laccase-mediated Biomimetic Synthesis and Antiproliferative Activity
European Journal Organic Chemistry 12, 902-918 (2012)
V. Vinod, C. Spatafora, C. Daquino, C. Tringali, S. Priya, S. Gopala
Phenethyl caffeate benzo[kl]xanthene lignan with DNA interacting properties induces DNA damage and apoptosis in
colon cancer cells.
Life Sciences, 91, 1336-1344 (2012)
M. G. Sarpietro, C. Spatafora, S. Ottimo, C. Tringali, F. Castelli
Interaction of resveratrol analogues with biomembrane models: a calorimetric study of structural variations effects
Journal of Excipients and Food Chemicals 3, 96-105 (2012)
C. Spatafora, C. Daquino, C. Tringali, R. Amorati.
Reaction of benzoxanthene lignans with peroxyl radicals in polar and non polar media: cooperative behaviour of OH
groups
Organic & Biomolecular Chemistry 11, 4291-4294 (2013)
C. Spatafora, E. Barbagallo, V. Amico, C. Tringali. Grape stems from Sicilian Vitis vinifera cultivars as a source of
polyphenol-enriched fractions with enhanced antioxidant activity.
LWT-Food Science and Techology in press