University of Virginia Health System Department of Pharmacy Residency Program Resident Research Projects 2013-2014 Thomas DiPiro Amanda Liszewski Alia (Lia) Lynch Laura Mincemoyer Amy Morris Karen Partlow Michael Bedenbaugh (PGY2-Administration) Kelly Gaertner (PGY2-Oncology) Nate Hedrick (PGY2-Critical Care) Michelle Hurrell (PGY2-Transplant) Terran Rice (PGY2-Informatics) Evaluation of adverse effects after intravenous antihypertensives given as-needed in postsurgical patients Retrospective comparison of continuous versus intermittent hydrocortisone dosing among patients with septic shock Evaluation of UFH dosing for suspected or proven VTE in obese patients Insulin infusion protocol in L & D Evaluation of ipilimumab-induced autoimmunity on efficacy outcomes for metastatic melanoma Evaluation of 30-day medication-related readmissions Implementing and assessing the impact of cost control and supply chain strategies on pharmaceutical expenditures at an academic medical center Evaluation of guideline-driven supplemental Gram positive antibiotic coverage for febrile neutropenia Appropriateness of antimicrobial selection upon referring hospital transfer to the MICU Safety and efficacy evaluation of new vs. prior immunosuppression protocol for adult kidney transplant recipients Implementation of decentralized Baxa Abacus server 2012-2013 Michael Bedenbaugh Nate Hedrick Hasan Kazmi Karen Nenno Jessica Traeger Michelle Zacchetti James Fiebert (PGY2-Informatics) Kyle Luedtke (PGY2-Critical Care) Phillip Mohorn (PGY2-Critical Care) Emily Prabhu (PGY2-Administration) Jeremy Sen (PGY2-Oncology) Evaluation of a clinical decision support (CDS) tool to aid in the prevention of propofol infusion syndrome (PRIS) The prevalence of characteristic symptoms of propofol-related infusion syndrome (PRIS) in patients treated with valproic acid Opportunistic Infections in Solid Organ Transplant Patients on Twice-Weekly SingleStrength Sulfamethoxazole-Trimethoprim Prevalence of Venous Thromboembolism Post-kidney transplant: a single center experience Use of medications that may prolong the QTc interval in infants and children in the pediatric intensive care unit Respiratory depression and other serious adverse events from opioid narcotics in postoperative orthopedic surgery patients Targeted best practice alerts for selected black box warnings Evaluation of a massive blood transfusion protocol at a Level I trauma institution The use of dexmedetomidine for sedation in patients with toxicological events Implementation of a pharmacy technician technology assisted medication validation program Evaluation of previous lenalidomide exposure on stem cell mobilization with plerixafor plus G-CSF in multiple myeloma patients 2011-2012 Carrie Hall Kyle Luedtke Phillip Mohorn Jeremy Sen Scott Anderson (PGY2-Informatics) Kate Bidwell (PGY2-CC) Wennie Huang (PGY2-CC) Abigail Reeder (PGY2-Administration) Geralyn Waters (PGY2-DI) Nicole Watts (PGY2-Oncology) Management of hyperglycemic emergencies and adherence to insulin infusion protocols at an academic medical center Evaluation of off-label prescribing in a children’s rehabilitation center Impact of clinical pharmacy services in the emergency department on the timing of antimicrobial therapy initiated in patients with sepsis Clinical evaluation of pentoxifylline mitigation of amphotericin B nephrotoxicity Evaluation of nursing efficiency following implementation of a streamlined medication administration process using a single access point for clinical nursing activities Evaluation of a non-paralytic based anti-shivering protocol used in patients undergoing therapeutic hypothermia for out-of-hospital cardiac arrest. High-dose acyclovir dosing protocol for HSV encephalitis. Implementation of a technician career ladder and comprehensive training program Impact of drug shortages on patient care at an academic medical center A pilot project for mixing chemotherapy in advance of infusion center arrival in breast cancer patients and effects on wait times 2010-2011 Bennett Bain Ahmed Mahmoud Julie Villanueva Nicole Watts Philip Almeter (PGY2-Management) David Crowther (PGY2-DI) Sarah Gruber (PGY2-CC) Amanda Williams (PGY2-CC) Impact of an increased inoculum and resistance mechanisms on in vitro antibiotic susceptibility in multi-drug resistant Enterobacteriaceae The use of albumin, midodrine and octreotide therapy in the hepatorenal syndrome patient at the University of Virginia Health System Safety and efficacy of same day pegfilgrastim with docetaxel in prostate cancer patients Analysis of dronabinol for nausea and vomiting in the inpatient neurosurgical population Improved medication management in the operating room Boxed warnings: an analysis of compliance Evaluation of antipsychotic use and clinical outcomes in CAM-ICU positive compared to CAM-ICU negative patients in the medical intensive care unit following implementation of an ICU delirium guideline Interdisciplinary antimicrobial stewardship in the thoracic/cardiovascular post-operative unit 2009-2010 Philip Almeter David Crowther Sarah Gruber Jennifer Neal Amanda Williams Brenda Clark (PGY2-CC) Nathan Powell (PGY2-CC) Prospective evaluation of outcomes in critically ill surgical/trauma patients receiving dexmedetomidine infusions greater than twenty-four hours Analysis of pediatric adverse drug events (ADE) in the University of Virginia Health System Initial statin dose in men versus women admitted for acute coronary syndrome at University of Virginia Health System: a prospective study Assessment of the effect of exenatide use on weight, A1C and lipids for patients seen in an ambulatory endocrinology clinic Antimicrobial prophylaxis following re-operation for bleeding in the thoracic/cardiovascular surgery intensive care unit Delirium in a medical intensive care unit Antibiotic usage during two antibiotic cycling programs 2008-2009 Jessica Johnson Shaila Patel Nathan Powell Whitney Raper Susan Cogut (PGY2-DI) Amber Ormsby (PGY2-CC) Chrissie Shirley (PGY2-CC) Venous thromboembolism prophylaxis in cancer patients: an evaluation of current practice at an academic medical center An evaluation of weight documentation for adult patients receiving weight-based medications Evaluation of a DVT/PE Prophylaxis Quality Initiative in a Neurosurgical Population Initiation of a pharmacist-led smoking cessation clinic in a tertiary medical center Assessment of Literature Evaluation Skills Among Pharmacy Residents Quality practice review of the utilization of sedative agents in a Surgical Trauma Intensive Care Unit Medication use evaluation of fluconazole in the thoracic-cardiovascular post-operative unit 2007-2008 Barry Barns Kelly Branham Susan Cogut Young Ran Lee Amber Ormsby Trisha Branan (PGY2-CC) Tina Grof (PGY2-CC) Rosuvastatin: Co-administration with warfarin and the effect on INR The Incidence and Treatment of Ventriculitis Associated with Extraventricular Drains in the Subarachnoid Hemorrhage Patient Population Alternate-day dosing of HMG-CoA reductase inhibitors Development of Erythropoietin Stimulating Agents (ESAs) guidelines and evaluation of ESA use in the hematology/oncology population The incidence of anemia among heart failure patients treated with angiotensin-converting enzyme inhibitors versus angiotensin II receptor blockers Medication use evaluation of anidulafungin for invasive fungal infections at a tertiary medical center Determining the appropriate titration dosing modality of dexmedetomidine in neurocritical care patients University of Virginia Health System Department of Pharmacy Residency Program Medication Use Evaluations (MUEs) 2013-2014 Thomas DiPiro Amanda Liszewski Alia (Lia) Lynch Laura Mincemoyer Amy Morris Karen Partlow Michael Bedenbaugh (PGY2-Administration) Kelly Gaertner (PGY2-Oncology) Nate Hedrick (PGY2-Critical Care) Michelle Hurrell (PGY2-Transplant) Terran Rice (PGY2-Informatics) Assessment of adherence to an institutional intravenous immune globulin (IVIG) guideline at an academic medical center Evaluation of adherence to institutional clinical practice guidelines for the management of hyperglycemic emergencies in the emergency department of a tertiary care academic hospital Evaluation of paclitaxel protein-bound, brentuximab, and carfilzomib utilization at an academic medical cetner Evaluation of an adult weight-based heparin nomogram in the emergency department at a large academic medical center Utilization and therapeutic outcomes of rivaroxaban in oncology patients at an academic medical center Impact of an automated systemic inflammatory response syndrome (SIRS) best practice alert on the post-operative patient Evaluation of medication overrides from automated dispensing cabinets Evaluation of interventions following automated sepsis alerts in hospitalized hematology/oncology patients Recombinant tissue plasminogen activator administration during cardiac arrest secondary to presumed pulmonary embolism Evaluation of a trigger-fill method of dispensing thymoglobulin in an academic medical center Evaluation of alternative alerts for drug shortages 2012-2013 Michael Bedenbaugh Nate Hedrick Hasan Kazmi Karen Nenno Jessica Traeger Michelle Zacchetti James Fiebert (PGY2-Informatics) Kyle Luedtke (PGY2-Critical Care) Phillip Mohorn (PGY2-Critical Care) Emily Prabhu (PGY2-Administration) Jeremy Sen (PGY2-Oncology) Evaluation of adherence to intravenous acetaminophen restriction and conversion The use of parenteral phenytoin sodium following the removal of restrictions on fosphenytoin prescribing Analysis of recombinant activated factor vii use: adherence to hospital guidelines and its medication use process Assessment of proton pump inhibitor usage at a tertiary academic medical center in patients with documented Clostridium Difficile infections. Evaluation of albumin usage in the adult inpatient setting Evaluation of the incidence of droperidol-associated QTc prolongation and assessment of adherence to current formulary restrictions Controlled substance removals from non-profiled automated dispensing cabinets Evaluation of use and adherence to Factor IX Complex guidelines Evaluation of definitive treatment for pneumococcal bacteremia Assessment of adherence of intravenous to oral medication conversions per policy at an academic medical center Evaluation of intravenous iron utilization and hypersensitivity reactions at an academic cancer center 2011-2012 Carrie Hall Kyle Luedtke Phillip Mohorn Jeremy Sen Scott Anderson (PGY2-Informatics) Kate Bidwell (PGY2-CC) Wennie Huang (PGY2-CC) Abigail Reeder (PGY2-Management) Geralyn Waters (PGY2-DI) Nicole Watts (PGY2-Oncology) An evaluation of echinocandin use in the pediatric population Evaluation of venous thromboembolic prophylaxis: are we adhering to our own guidelines? Tranexamic acid use in total hip and knee arthroplasty at an academic medical center Evaluation of the use of intravitreal ranibizumab and bevacizumab use in the outpatient ophthalmology clinic at a university medical center Evaluation of ipilimumab use at an academic medical center Evaluation of the addition of a standardized medication packet to the current STEMI alert process in the emergency department of an academic medical center Evaluation of the use of intravenous acetaminophen at a university medical center. Evaluation of the adherence to formulary restriction of pantoprazole in an academic medical center Evaluation of dabigatran use in the inpatient setting at an academic medical center Use of fosaprepitant for chemotherapy-induced nausea and vomiting in an outpatient cancer center 2010-2011 Bennett Bain Ahmed Mahmoud Julie Villanueva Nicole Watts Philip Almeter (PGY2-Management) David Crowther (PGY2-DI) Sarah Gruber (PGY2-CC) Amanda Williams (PGY2-CC) Evaluation of clinical outcomes following the change in the United States Pharmacopoeia monograph for unfractionated heparin when used for thromboprophylaxis in hospitalized patients Medication use evaluation of intravenous fenoldopam as a renal protective agent in the abdominal aortic aneurysm vascular surgery patient Evaluation of stress ulcer prophylaxis use after transfer from an intensive care unit Therapeutic outcomes and cost associated with high dose aldesleukin at an academic medical center Evaluating the use of intravenous immunoglobulin (IVIG) and methods to decrease off-labeled utilization and associated costs Venous thromboembolism (VTE) risk associated with dalteparin use compared to enoxaparin use in UVaHS trauma patients Evaluation of the benefits and risks of off-label recombinant factor VIIa use in cardiovascular surgery and surgical trauma patients at a university hospital Acetazolamide use in the pediatric intensive care unit 2009-2010 Philip Almeter David Crowther Sarah Gruber Jennifer Neal Amanda Williams Brenda Clark (PGY2-CC) Nathan Powell (PGY2-CC) Evaluation of sodium polystyrene sulfonate (SPS) in the treatment of hyperkalemia in the emergency department Tigecycline use at an academic medical center: an assessment of resistance trends and patient outcomes Evaluation of recombinant Factor VIIa use in a thoracic cardiovascular post operative and surgical intensive care unit Evaluation of naloxone use in the emergency department at an academic medical center Albumin use in a pediatric intensive care unit Dalteparin use in medical and surgical/trauma intensive care units at a university hospital Evaluation of vancomycin therapeutic drug monitoring in a university teaching hospital 2008-2009 Jessica Johnson Shaila Patel Nathan Powell Whitney Raper Susan Cogut (PGY2-DI) Amber Ormsby (PGY2-CC) Chrissie Shirley (PGY2-CC) Evaluation of intravenous nicardipine use in the neurointensive care unit at an academic medical center Evaluation of varenicline use in the ambulatory care setting Evaluation of insulin glargine use in intensive care units at an academic medical center Analysis of rosiglitazone discontinuation in a tertiary medical center following safety warning and black box warning additions Extravasations Treated with Phentolamine and Hyaluronidase Dexmedetomidine in the adult critical care population The use of oral vancomycin for Clostridium difficile 2007-2008 Barry Barns Kelly Branham Susan Cogut Young Ran Lee Amber Ormsby Trisha Branan (PGY2-CC) Tina Grof (PGY2-CC) Prospective medication use evaluation (MUE) of promethazine injection at a tertiary care center A Prospective Medication Use Evaluation of Ertapenem Usage patterns of fondaparinux at an academic medical center Evaluation of the Formulary versus Non-formulary Use of Rituximab in an Academic Tertiary Care Medical Center Evaluation of the use of rifaximin in the inpatient care setting Medication use evaluation of argatroban for heparin-induced thrombocytopenia at an academic medical center Re-evaluation of recombinant factor VIIa adherence to University of Virginia Health System Guidelines