Program Tuesday, May 21, 2013 20:00 Meeting point : “Café het Spijker” and “Café het Gouden Mandeke”, Pensmarkt 3 and 9, 9000 Ghent Wednesday, May 22, 2013 8:00 Registration 8:50 Welcome Prof. Dr. S. De Saeger, Chair Organizing Committee Prof. Dr. S. Croubels, Chair Organizing Committee 9:00 Welcome Prof. Dr. P. Van Cauwenberge, Rector Ghent University Prof. Dr. G. Haesaert, Dean University College Ghent Prof. Dr. H.U. Humpf, President of the Society for Mycotoxin Research DETECTION Chair: Prof. Dr. S. De Saeger and Prof. Dr. A. Wu 9:30 L1 Combination of double isotopic labeling and high resolution mass spectrometry: a novel method for untargeted fungal metabolic profiling P.M. Cano, E. Jamin, S. Tadrist, P. Bourdaudhui, M. Péan, L. Debrauwer, I.P. Oswald, M. Delaforge and O. Puel 9:45 L2 Untargeted stable isotope assisted metabolic profiling reveals novel conjugates of deoxynivalenol in wheat B. Kluger, C. Bueschl, R. Krska, M. Lemmens, G. Adam and R. Schuhmacher 10:00 L3 Metabolic profiling of Aspergillus flavus: identification and fragmentation study of the cluster 27 polyketide synthase metabolites by high resolution and multi-stage mass spectrometry S.V. Malysheva, N. Aroyo-Manzanares, J.W. Cary, K.C. Ehrlich, J. Vanden Bussche, L. Vanhaecke, D. Bhatnagar, J. Diana Di Mavungu and S. De Saeger 10:15 Coffee break / Exhibition / Poster Session 11:00 L4 LC-MS-based methods for multi-mycotoxin determination in maize: a critical evaluation A. De Girolamo, M. Solfrizzo, V.M.T. Lattanzio, J. Stroka, A. Alldrick, H.P. van Egmond and A. Visconti 11:15 L5 A promising grain sampling technique: the sampling of wheat dust and subsequent UPLC-MS/MS analysis M. Sanders, M. De Boevre, F. Dumoulin, C. Detavernier, Y. Guo, F. Martens, M. Eeckhout and S. De Saeger 11:30 L6 A LC-MS/MS method for the simultaneous determination of zearalenone, deoxynivalenol and metabolites in pig serum U. Brezina, I. Rempe, H. Valenta, Susanne Kersten, H.-U. Humpf and S. Dänicke 11:45 L7 Fast and sensitive LC-MS/MS method measuring human mycotoxin exposure using biomarkers in urine B. Huybrechts, P. Debongnie, S. Uhlig and A. Callebaut 12:00 Lunch 13:00 13:30 Poster Session / Exhibition Meeting of the members of the Society for Mycotoxin Research DETECTION Chair: Prof. Dr. P. Karlovsky and Dr. I. Tothill 14:30 L8 Fluorescence polarization immunoassays for the determination of mycotoxins in foodstuffs V. Lippolis, M. Pascale and A. Visconti 14:45 L9 Quantum dots for use as labels for mycotoxin detection: preparation of hydrophilic quantum dots by encapsulation with polymer E.S. Speranskaya, V.V. Goftman, S. De Saeger and I.Yu. Goryacheva 15:00 L10 Hapten microarray-based screening of mycotoxins in cereals S. Oswald, R. Niessner and D. Knopp 15:15 Coffee break/Exhibition/Poster Session PRODUCTION AND OCCURRENCE Chair: Prof. Dr. P. Karlovsky and Prof. Dr. R. Geisen 15:45 L11 Matrix binding of ochratoxin A during thermal processing A. Bittner, B. Cramer and H.-U. Humpf 16:00 L12 Masked mycotoxins: facts and figures 2009-2013 M. De Boevre, S. Landschoot, L. Jacxsens, C. Lachat, A. Vanheule, M. Eeckhout, J. Diana Di Mavungu, K. Audenaert, P. Maene, B. De Meulenaer, G. Haesaert and S. De Saeger 16:15 L13 Correlation of ergot alkaloids and sclerotia in German rye and wheat and recommendation to simplify analyses E. Sciurba, S. Lewandowska, S. Seling, M.G. Lindhauer and C. Schwake-Anduschus 17:00 Boat trip in ancient city of Ghent Meeting point : Snepkaai – pier “Restaurant ‘t Patijntje” (Gordunakaai 91, 9000 Ghent) (about 20 min walking distance) 18:00 Welcome reception Meeting point : Town Hall of Ghent, Botermarkt 1, 9000 Ghent Thursday, May 23, 2013 8:00 Registration PRODUCTION AND OCCURRENCE Chair: Prof. Dr. H.-U. Humpf and Prof. Dr. C. Dall’Asta 9:00 L14 Screening biodiversity of toxigenic fungi for a correct evaluation of mycotoxin risk on important food crops: the contribution of EU project MycoRed, at a global level A. Moretti, G. Mulè, G. Perrone, A. Susca and A. Logrieco 9:15 L15 Fungal growth and mycotoxin production during cocultivation of phytopathogenic Fusarium and Alternaria strains M. Müller, I. Steier, R. Köppen, D. Siegel, U. Korn and M. Koch 9:30 L16 Interaction of free air carbon dioxide enrichment (FACE) and water availability on eoxynivalenol concentration in maize and sorghum E. Oldenburg, R. Manderscheid, M. Erbs and H.-J. Weigel 9:45 L17 Upregulation of sterigmatocystin and other putative mycotoxins in Aspergillus nidulans after feeding damage by Folsomia candida M. Rohlfs, S. Chatterjee, K. Döll, P. Karlovsky and S. Scheu 10:00 Coffee break/Exhibition/Poster Session 10:45 L18 Chlorogenic acid, a metabolite identified in tomato fruits by a metabolomics approach, is inhibitory against the biosynthesis of alternariol by Alternaria alternata E. Wojciecowska, C.H. Weinert, B. Horneburg, S. Zikeli, S. Graeff-Hoenninger, S.E. Kulling and R. Geisen 11:00 L19 New secondary metabolites of F. fujikuroi – a combined biological and chemical approach K. W. von Bargen, E.-M. Niehaus, B. Tudzynski and H.-U. Humpf 11:15 L20 Tenuazonic acid in infant products – a risk for the consumer? M. Rychlik and S. Asam 11:30 L21 The publication of mycotoxin results exceeding the maximum levels in foodstuffs – an increase in market transparency? S. Marschik and D. Bolay 11:45 L22 Chemical interactions between Fusarium verticillioides and Gliocladium roseum involving mycotoxin transformation Y. Kuang, S. Chatterjee, K. Scherlach, R. Splivallo, P. Chatterjee, C. Hertweck and P. Karlovsky 12:00 Lunch 13:00 Poster Session/Exhibition PRODUCTION AND OCCURRENCE Chair: Prof. Dr. S. Croubels and Prof. Dr. R. Krska 14:00 L23 Fusarium poae: chemotype, plant-pathogen interaction and response to oxidative stress 14:15 L24 Population structure and mycotoxin production of Fusarium species from greenhouse pepper fruit in China J. Wang, Z. Feng, Z. Han, S. Song and A. Wu A. Vanheule, K. Audenaert, S. De Saeger, M. Höfte and G. Haesaert IMPACT ON ANIMAL AND HUMAN HEALTH Chair: Prof. Dr. S. Croubels and Prof. Dr. R. Krska 14:30 L25 Impact of monacolin K on animal health: preliminary test of rumen stability K. Meyer, H. Hohagen, G. Breves and J. Bauer 14:45 L26 Zearalenone-mediated toxicity in fish in vitro and in vivo C. Pietsch 15:00 L27 The impact of mycotoxin co-occurrence on necrotic enteritis in broilers G. Antonissen, F. Van Immerseel, F. Pasmans, R. Ducatelle, F. Haesebrouck, L. Timbermont, M. Verlinden, M. Eeckhout, S. De Saeger, E. Delezie, S. Hessenberger, A. Martel and S. Croubels 15:15 L28 Expression of immune response genes in broiler chickens fed deoxynivalenol and a counteragent K. Ghareeb, W. Awad, S. Sasgary, A. Strasser and J. Böhm 15:30 Coffee break / Exhibition / Poster Session 16:15 L29 Detection of Fusarium mycotoxins and carry over to animals and humans: case study poultry E. Van Pamel, E.K. Tangni, E. Delezie, P. Debongnie, A. Callebaut and E. Daeseleire 16:30 L30 New results for ochratoxin A analysis in infants’ urines G.H. Degen, M. Blaszkewicz and K. Munoz 19:00 Conference Dinner Meeting point : “Handelsbeurs“, Kouter 29, 9000 Ghent Friday, May 24, 2013 8:00 Registration REDUCTION AND PREVENTION Chair: Prof. Dr. J. Fink-Gremmels and Dr. I. Oswald 9:00 L31 Microbes as bio-control agents against Fusarium pathogens and mycotoxins Y.-C. Liao, H.-P. Li, J.-B. Zhang, A.-D. Gong, W.-J. He and Q.-S. Yuan 9:15 L32 Isolation of Rhodococcus erythropolis MTHt3 and cloning of ergA for ergopeptine hydrolysis and ergB for ergine deamination M. Thamhesl, E. Apfelthaler, I. Schöner, H. Schwartz, F. Berthiller, G. Schatzmayr and W.-D. Moll 9:30 L33 Development of an vitro method for the prediction of mycotoxin adsorption on yeast-based products: case of zearalenone, ochratoxin A and aflatoxin B1 V. Faucet-Marquis, C. Joannis-Cassan, K. Hadjeba-Medjdoub, N. Ballet and A. Pfohl-Leszkowicz 9:45 Coffee break/Exhibition/Poster Session TOXICOLOGY Chair: Prof. Dr. J. Fink-Gremmels and Dr. I. Oswald 10:30 L34 New insights into mycotoxin mixtures: the toxicity of low doses of type B trichothecenes against intestinal epithelial cells is synergistic I. Alassane-Kpembi, M. Kolf-Clauw, T. Gauthier, R. Abrami, F.A. Abiola, I.P. Oswald and O. Puel 10:45 L35 New insights into the toxicological effects of altertoxin II from Alternaria alternata S.C. Fleck, E. Pfeiffer and M. Metzler 11:00 L36 Genotoxic properties of alternariol and its phase I metabolite 4-OH-alternariol C. Tiessen, H. Gehrke, D. Ellmer, H. Mikula, J. Fröhlich and D. Marko 11:15 L37 In silico evaluation of interactions between mycotoxins and estrogen receptors. A bioinformatic tool to predict and understand endocrine disrupting activity. L. Dellafiora, C. Dall’Asta and P. Cozzini 11:30 Closing session