COMPLETED STUDY SAMPLE ABSTRACT
Predictors of Metabolic Syndrome and its Resolution in Bariatric Surgery Patients
Karen J. Coleman, Kristi Reynolds, Winnie Y. Huang, Corinna Koebnick, and Steven J. Jacobsen;
Southern California Permanente Medical Group, Pasadena, CA
Objective: To determine predictors of metabolic syndrome and its resolution in an ethnically diverse
adult population undergoing bariatric surgery.
Methods: Patients were selected for the study if they had a bariatric procedure in 2007 and 2008 and
complete medical information for the determination of metabolic syndrome within six months of
surgery and two years after surgery (n = 2,431). Diagnosis and resolution of metabolic syndrome
were determined using the AHA/NHLBI criteria.
Results: Patients were primarily women (82%), from a racial/ethnic minority group (50%), mean age
of 47 years, and mean BMI of 46.69 kg/m2. Most patients had a gastric bypass procedure (83%). A
total of 1,351 (56%) had metabolic syndrome. Patients were more likely to have metabolic syndrome
before surgery if they had a higher BMI and were older. NonHispanic black patients were less likely
to have metabolic syndrome as compared to nonHispanic whites. A total of 774 patients with
metabolic syndrome at the time of surgery (57%) resolved within two years. Average time to
resolution was two months, ranging from 3 days to 21 months. Resolution rates were lowest for
patients having laparoscopic banding, gastric sleeve, older age, less weight loss, and for those
patients who were nonHispanic black or Hispanic.
Conclusions: While the prevalence of metabolic syndrome in this cohort was similar to that reported
in the literature, resolution rates were much lower. These findings have implications for determining
the impact of bariatric surgery on metabolic syndrome at the population level and in racial/ethnic
minorities.
Funding provided by the Southern California Permanente Medical Group.