Gynura Procumbens an annual evergreen shrub found in Southeast Asia, especially Malaysia, Thailand and Indonesia, which is of considerable medicinal value. Gynura procumbens is an evergreen shrub found in Southeast Asia, especially Malaysia, Thailand and Indonesia, which is of considerable medicinal value. It has found its way around the world and is widely used as an accepted medicine for diabetes, HTN, and elevated levels of cholesterol and triglycerides. Its Chinese name is ‘jian feng wei’ (尖凤尾 which translates into ‘pointed phoenix tail’) and Indonesian name is ‘daun sambung mjawa’. It should not be confused with daun dewa which is another related Gynura species. Gynura cuttings sell from $5 to $35 each depending on how big and where you are located. Contains Asparaginase, kind of enzyme to inhibit protein syntheses by hydrolyzing asparagines (amino acid which is very essentially, needed by cancer/tumor cells) into aspartic acid and ammonia, so the cancer cells/tumor cells will stop growing and die. The plant is also known as the Longevity Spinach, Leaf of the Gods, Akar Sabiak, Kecam Akar and Sambung Nyawa in Malaysia. It is called Longevity Spinach cause it is known to cure many diseases. The herb has anti-viral, anti-inflammatory, anti-oxidant and anti-allergy properties. Some of its uses include - migraines, constipation rheumatism, diabetes, dysentery, fevers, kidney ailments, cardiovascular conditions, cancers, leukaemia, and as a skin care elixir. Popular for reversing diabetes mellitus. The herb can be eaten fresh, mixed with salads, in stir fry or added to vegetables or prepared as tea. An herb which has been regularly used to treat fever, rash and kidney failure. Recent research helps diabetes mellitus patients to suppress sugar level in the blood. Method of Consumption : It is not to be eaten with coffee and tea as these two have caffeine in them. Give at least 4 hours in between taking gynura procumbens and coffee/tea. ( ? have only see this once in all searches on gynura). There are several methods for consumption of Gynura Procumbens. There is no straight and fast rule on method to consume Gynura Procumbens. According to what I have heard from the patients taking it, I shall suggest 3 methods for the preparation of Gynura Procumbens before consumption. 1) The most effective way - EAT IT RAW. Wash the Gynura Procumbens leaf before consumption. The extracts of the leaf is proven to be the substance that can reduce the sugar level in the blood. To absorb the supplement directly from eating it raw is a highly recommended method of consumption. 2) Dry the leaves and consume like tea. Gynura Procumbens leaves can be sun-dried and preserved like tea leaves. However, as mentioned earlier, the extracts of the leaves are the vital extract for this supplement; this method may not be as effective as the earlier one mentioned above. TEA: bring fresh leaves to low boiling for ten minutes. Boil fresh leaves in water, drink 1 cup size 3 times a day. Leaves can be eaten after boiling. Leaves can be sun-dried and preserved like tea leaves. 3) Soaked the leaves into alcohol and preserved it. Consume the leaves as required. I personally never recognized and recommend this method. Diabetes Mellitus patients are highly likely to suffer from kidney failure as a side effect. However, alcohol is never a intake for kidney. This is why I strongly discourage patients from using this method despite it is widely used by many. The boiled leaves are applied externally to relieve general body pains and raw leaves for rheumatic pains. Dried and pounded leaves are mixed with oil and applied as a poultice to treat skin compliants. It also used for the treatment of kidney problems and dysentery. Below are a few related web sites: http://www.sma.org.sg/smj/4101/articles/4101a2.htm http://myais.fsktm.um.edu.my/5274/ An amazing edible herb Gynura procumbens has been used as “FOLK MEDICINE” for hundreds of years. This herb has been found to be an extremely alkalizing and miraculous antiviral, anti-inflammatory edible plant. High in antioxidants Gynura procumbens offers the possibility of remarkable results when it comes to improving overall health and longevity, and aiding in conditions such as diabetes, high blood pressure and cholesterol. It's also been known to significantly support the detoxification process. • Anti-Inflammatory: Study of ethanol extract showed antiinflammatory activity. • Antihypertensive: Study showed the oral administration of aqueous extract significantly lowered blood pressure in spontaneously hypertensive rats. Results suggest GPE may be useful for prevention and treatment of hypertension through increasing NO (nitric oxide) production in blood vessels. • Glucose Lowering: Ethanolic extract of leaves significantly suppressed elevated serum glucose levels in diabetic rats. The extract did not significantly suppress glucose levels in normal rats. Results conclude the leaves of GP may be biguanide-like activity. • Abundant Leaf Proteins / Peroxidase: Study found few abundant proteins from the leaves of GP; among these, peroxidase was found the most abundant of the extracted proteins. Results suggest a natural source for peroxidase for use in the cosmetic and skin care industry. • Nutritive / Antioxidative Properties: Ethanolic Gynura extract exhibited the highest antioxidative properties in every assay. Nutritive evaluation suggests the extract is a good protein source and may have positive effects on free radical scavenging and iron chelating. • Gynura procumbens Medical Toothpaste: A Gynura procumbens toothpaste invention consists of" gynura procumbens (Lour.) extractant of 1-20%, glycerol of 20-55%, diglycol of 10-15%, abradant of 20-45%, carboxymethyl cellulose of 0.5-1.5%, sodium dodecyl sulfate of 0.5-2%, additive of 1-4%, essence of 1-2% and saccharin of 0.1-1%. • Anti-Ulcerogenic: Study results suggest the ethanolic leaf extract of Gynura procumbens promotes ulcer protection as shown by significant reduction of ulcer area, histologic decreases in ulcer areas, with absence or reduction of edema and leucocyte infiltration of submucosal layer. • Anti-Diabetic: (1) Study evaluating the water extract of G. procumbens in streptozotocin-induced diabetic rats showed a hypoglycemic effect by promoting glucose uptake by muscles. (2) Study results suggest the antidiabetic effect may be mediated through the stimulation of glucose uptake and the potentiation of insulin action. • Toxicological Evaluation: Administration of a methanol extract of G. procumbens did not produce mortality or significant changes in various parameters in both acute and sub-chronic toxicity studies. Medicinal Folk Medicine Uses. It is said that: • Lowers blood sugar (diabetes), cholesterol (lipid, serum, triglyceride levels). • Topical inflammation, rheumatism, viral ailments, diarrhea, dysentery, febrifuges, hypertension, urinary tract infection, anti-inflammatory, anti-allergic. • Anti-cancer: Inhibition effect on growth of cancer cells. • Contains Asparaginase, kind of enzyme to inhibit protein syntheses by hydrolyzing asparagines (amino acid which is very essentially, needed by cancer/tumor cells) into aspartic acid and ammonia, so the cancer cells/tumor cells will stop growing and die. • Poultice: relieves rheumatic and general body-pains. This FRESH LEAF that YOU GROW is packed full of LIVE Super Antioxidants, LIVE Enzymes, and antiviral, anti-inflammatory, Super Alkalizing characteristics. Gynura procumbens can be eaten fresh like a salad, stir fried with other vegetables, juiced, and also enjoyed as a cup of tea. It has a very delicious taste. Abstract: The present study determined nutritional value in various parameters such as moisture content, carbohydrate, protein, lipid as standard methods and evaluated the antioxidative properties of the medicinal plant Gynura procumbens Extract by hydroxyl scavenging activity, ferrous ion-chelating activity and inhibition of lipid peroxidation. The highest extraction yield was obtained from extraction with distilled water (84.51%). While, Ethanolic Gynura extract (EGE) exhibited the highest in the antioxidative properties in every assay, EC50 = 1.63 in hydroxyl scavenging test, EC50 = 2.17 in chelating activity test and EC50 = 2.75 in inhibition of lipid peroxidation test. Although, the content still low (186.25±0.00018 to 300.18±0.0003 μg GAE g-1 of extract). According determination the nutritional values was found that Gynura procumbens Extract were containing the contents of moisture was 7.08%, carbohydrate was 0.0537 to 0.1968 μg glucose equivalent/100 g dry weight at EGE 0.1 μg mL-1, protein was 4.51 g/100 g dry weight and lipid was 0.023 g/100 g dry weight. These results suggest that Gynura Extract is a good protein source and that they may have positive effects on free radical scavenging and iron chelating which may use as preliminary information and develop further to be commercially useful in food industry or health products as medicinal food. Evaluation of nutritional value and antioxidative properties of the medicinal plant Gynura procumbens extract Mahasarakham University, Thailand The present study determined nutritional value in various parameters such as moisture content, carbohydrate, protein, lipid as standard methods and evaluated the antioxidative properties of the medicinal plant Gynura procumbens Extract by hydroxyl scavenging activity, ferrous ion-chelating activity and inhibition of lipid peroxidation. The highest extraction yield was obtained from extraction with distilled water (84.51%). While, Ethanolic Gynura extract (EGE) exhibited the highest in the antioxidative properties in every assay, EC50 = 1.63 in hydroxyl scavenging test, EC50 = 2.17 in chelating activity test and EC5n = 2.75 in inhibition of lipid peroxidation test. Although, the content still low (186.25?0.00018 to 300.18?0.0003 ug GAE g-1 of extract). According determination the nutritional values was found that Gynura procumbens Extract were containing the contents of moisture was 7.08%, carbohydrate was 0.0537 to 0.1968 ug glucose equivalent/100 g dry weight at EGE 0.1 ug mL-1, protein was 4.51 g/l00g dry weight andhpid was 0.023 g/100 g dry weight. These results suggest that Gynura Extract is a good protein source and that they may have positive effects on free radical scavenging and iron chelating which may use as preliminary information and develop further to be commercially useful in food industry or health products as medicinal food. GROWING This plant grows easily from stem-cuttings. Seeds are not available. It is best grown in well-draining, fertile soil that is kept moist at all times. Semi-shade is preferred by this plant although it can be slowly adapted to grow in full sun, provided the plant does not dry out at the roots. Initial planting under direct sunshine will result in burnt leaves and stunting in growth. Growth should resume once the plant has acclimatised to its new growing conditions. stems that can extend to 6 m long if left to grow http://docsdrive.com/pdfs/ansinet/ajps/2010/146-151.pdf Table 2: Mineral contents (weight %) of the anticancer plants analyzed C, O, Mg, P, S, Cl, K, Ca, Al, Si and Fe. Gynu-Herb® http://www.famepharma.com/gynuherb.htm COMPOSITION Organic Gynura procumbens air dried leaf powder ........... 300 mg ACTIVE CONSTITUENTS Gynura procumbens contains phytosterols (β-sitosterol and stigmasterol), sterol glycosides (3-O- -Dglucopyranosyl -sitosterol, 3-O- -D-glucopyranosyl stimasterol), nonadecane, phytyl valerate, adenosine, kaempferol-3-O-neohesperidoside, methyl hexadecanoate, methyl 9-octadecenoate, 4hydroxy -4-methyl-2-pentanone, stigmasterol acetate, quercetin-O-caffeoylquinic acid, 1, 2bisdodecanoyl-3--O-D-glucopyranosyl-Sn-glycerol. PHARMACOLOGICAL ACTIONS 1. Conversion of glucose to vitamin C Humans are one of the few species who lack the enzyme to convert glucose to vitamin C. According to the scientific study, Gynura procumbens leaves are rich in enzymes and coenzymes have ability to convert glucose to vitamin C in vitro. By taking orally it may transform plasma glucose to ascorbic acid inside our body. 2. Anti-diabetic Action The ethanol extract of Gynura procumbens was reported to be anti-hyperglycemic and anti-hyperlipidemic activities in diabetic rats. The extract of Gynura procumbens leaves may have biguanide-like activity. The extract showed similar effect to metformin by improving glucose tolerance (OGTT) in STZ-induced diabetic rats. The methanol extract and n-butanol fraction exerted a significant hypoglycemic effect when administered orally to streptozotocin-induced diabetic rats. The leaf extract of G. procumbens significantly reverse the adverse effects of elevated accumulation of intracellular glucose. It may be therapeutic potential for the treatment of diabetic retinopathy. 3. Anti-hypertensive action Gynura procumbens extract (GPE) administered rats had significantly lower serum lactate dehydrogenase, creatine phosphate kinase and increased nitric oxide, a known vasodilator and decreased the systolic & diastolic blood pressure. Glycoconjugated or peptidal substances found in GPE that exhibit an inhibitory effect on ACE. It is useful for prevention and treatment of hypertension through increasing nitric oxide production in blood vessels. INDICATIONS 4 Diabetes mellitus 4 Diabetic retinopathy & nephropathy 4 Hypertension 4 Hyperlipidemia & hypercholesterolemia Combination Therapy - It can also be used together with for more effective treatment. DOSAGE Adult : One capsule two times daily half-an-hour before meal or as directed by physician. CAUTION - To adjust the dosage of other hypoglycemic agent when use together with . - To consult with physician if taken during pregnancy. HOW SUPPLY 60 capsules per bottle. Medical study http://www.academicjournals.org/jmpr/PDF/pdf2012/9Feb/Lee%20et%20al.pdf Considered effective in treating the following disorders: Lungs / Cough / Asthma / Disgestive System / Intestine / Kidney / Kidney Stones / Urinary Tract Bleeding / Liver / Gall Bladder / Hepatitis / Gall Bladder Stones / Help Suppress Growth of Cancer Cells / Hemorroids / Constipation / Diarrhea / Vomitting / Blood Poisoning / Septicemia / Fertility Problems / More Balanced Blood Cells / Help in Recovery of Bone Injuries / External Wounds / Skin Allergy / Rheumatism / High Cholesterol Levels / High-Low Blood Pressure / Diabetes. Abundant in chlorophyll, which is shown to reduce the risk of cancer. The antioxidant properties in the plant make it beneficial for fighting free radicals (damaging molecules that promote aging, destroy tissues and promote disease in the body). Due to the plant's rich content of chlorophyll, B12 and antioxidants, it is recognized as a favorable herb for fighting disease and encouraging overall health. 1. Anti-Inflammatory: Study of ethanol extract showed antiinflammatory activity. 2. Antihypertensive: Study showed the oral administration of aqueous extract significantly lowered blood pressure in spontaneously hypertensive rats. Results suggest GPE may be useful for prevention and treatment of hypertension through increasing NO (nitric oxide) production in blood vessels. 3. Glucose Lowering: Ethanolic extract of leaves significantly suppressed elevated serum glucose levels in diabetic rats. The extract did not significantly suppress glucose levels in normal rats. Results conclude the leaves of GP may be biguanidelike activity. 4. Abundant Leaf Proteins / Peroxidase: Study found few abundant proteins from the leaves of GP; among these, peroxidase was found the most abundant of the extracted proteins. Results suggest a natural source for peroxidase for use in the cosmetic and skin care industry. 5. Nutritive / Antioxidative Properties: Ethanolic Gynura extract exhibited the highest antioxidative properties in every assay. Nutritive evaluation suggests the extract is a good protein source and may have positive effects on free radical scavenging and iron chelating. 6. Gynura procumbens Medical Toothpaste: A Gynura procumbens toothpaste invention consists of" gynura procumbens (Lour.) extractant of 1-20%, glycerol of 20-55%, diglycol of 10-15%, abradant of 20-45%, carboxymethyl cellulose of 0.5-1.5%, sodium dodecyl sulfate of 0.5-2%, additive of 1-4%, essence of 1-2% and saccharin of 0.1-1%. 7. Anti-Ulcerogenic: Study results suggest the ethanolic leaf extract of Gynura procumbens promotes ulcer protection as shown by significant reduction of ulcer area, histologic decreases in ulcer areas, with absence or reduction of edema and leucocyte infiltration of submucosal layer. 8. Anti-Diabetic: (1) Study evaluating the water extract of G. procumbens in streptozotocin-induced diabetic rats showed a hypoglycemic effect by promoting glucose uptake by muscles. (2) Study results suggest the antidiabetic effect may be mediated through the stimulation of glucose uptake and the potentiation of insulin action. 9. Toxicological Evaluation: Administration of a methanol extract of G. procumbens did not produce mortality or significant changes in various parameters in both acute and sub-chronic toxicity studies. Ashitaba leaves can be eaten fresh, rinse the leaves in water with salt then chew 1 to 2 leaves a day good for prevention... people experiencing above disorders my take more than 2 leaves... Read more: http://www.sulit.com.ph/index.php/view+classifieds/id/5196058/Gynura+Procumbens,+Miracle+Plant+a.k.a+Ashitaba+Plant+in+t he+phil. 1. Sinusitis and sore throat band Do I take 7 leaves fresh Gynura procumbens to treat adults or 4 bay leaves to treat children, and then washed cling and eat it fresh or used as juice, and performed a total of 1 times a day. 2. High blood pressure Take a fresh way of gynura procumbens leaves as much as 7 pieces if to treat adults, while children need 4 sheets of leaf Gynura. Then the leaves were eaten after being washed clean, or it could be on the juice, sauteed, steamed, or used as tea and then consumed. Do this once a day regularly. 3. Tumors. Take the raw leaves 3 pieces and washed before being eaten as fresh vegetables every day at meal time or used as a juice to drink every day. During treatment with the leaf Gynura procumbens prohibited to eat the following foods pineapple, durian fruit, jack fruit, longan, ice, drinks alcohol, tape, beverage or foods that contain artificial sweeteners and mono-sodium glutamate, salted fish, kale, watercress, chicory, bean sprouts, chili. 4, diabetes mellitus Take 3 fresh leaves later washed and eaten as fresh vegetables or juice then be eaten every day, and during treatment are prohibited to consume sugary drinks and foods. 5. Lever and high cholesterol Just as with the treatment of diabetes mellitus but the food is different and prohibited foods that contain fat during treatment. 6. Hemorrhoid. Just as the treatment of diabetes mellitus but different food taboos which prohibited eating are spicy and fatty foods. 7. Ulcer. Treatment of ulcer disease such as diabetes mellitus treats disease but forbidden to consume food that is sour and spicy foods. 8. Black ants or be affected by a caterpillar Method of treatment by taking a fresh bay leaves Gynura procumbens, and then rubbed on the body that itch until crushed leaves and result water from the leaves, and performed 2 times with 2-hour interval from first treatment