Name _______________________________ Date ______________ DNA Study Guide 1) What does DNA stand for? ________________________________ Deoxyribonucleic Acid 2) What makes up the ‘sides’ of the DNA molecule? Sugars and Acids, (Phosphates and -----) ________________________________ 3) What makes up the ‘rungs’ of the DNA molecule? ________________________________ Nitrogen bases that are ‘paired’/ BASE PAIRS or NUCLEOTIDES 4) What is the shape of the DNA molecule? ________________________________ Double Helix 5) What are nitrogen bases? ________________________________ ________________________________ A, (Adenine) G, (Guanine) T, (Thynine) C, (Cytosine) 6) What nitrogen bases can bond with each other? _______________ A with T C_________________ with G 7) Be familiar with completing the DNA molecule if given one side of the molecule… a. ATCGTTCCCC ________________________________ TCGCAAGGGG b. GGGATTCAA ________________________________ CCCTAAGTT 8) Know your ‘NUMBERS’… 4 a. ______________How many KINDS of nitrogen bases are there? BILLIONS b. ______________How many nitrogen bases, (base pairs), are there in a DNA molecule? 30,000 c. ______________How many human genes are there? 46 d. ______________How many chromosomes do humans have in body cells? 23 e. ______________How many chromosomes do humans have in sex cells? 9) What is a gene? a. What are other ways to define a gene? A small piece of DNA A part of a chromosome Genetic materials that code for specific traits Genetic material that determines which proteins will be assembled by the ribosomes. b. What do genes determine? (think traits AND proteins) Genes are an arrangement of nitrogen bases that contain the instructions for ___________________________________________________________ assembling proteins. Once made, these proteins are responsible for specific traits. 10) What is a mutation? (Think characteristics AND DNA code) A change in the DNA code ____________________________________________________________ _____________________________________________________________ An error in the swquence of nitrogen bases Radiation, Chemicals, Natural Sequencing Error 11) What can cause a mutation? A change in traits __________________________________________________________________ Radiation, Chemicals, Natural Sequencing Error 12) Understand DNA synthesis… During Interphase a. ___________________________________When does DNA replicate? In the nucleus of the cell b. ___________________________________Where is DNA replicated? 13) Understand how proteins are made… a. b. c. d. RIBOSOMES ___________________________Where in the cell is a protein made? RNA ___________________________What molecules carry the the DNA code? RIBOSOMES ___________________________What organelles make the proteins? AMINO ACIDS ___________________________What are proteins made up of? 14) How does RNA ‘help’ to make proteins? It ‘reads’ the DNA code and carries it to the ribosome _____________________________________________________________________ 15) Know the differences between DNA and RNA a. The differences in function: A template that contains the genetic instructions for making proteins i. DNA: _______________________________________________________ It ‘reads’ the DNA code and carries it to the ribosomes to make ii. RNA: _______________________________________________________ proteins b. The differences in structure: Made up of A,T,C, G i. DNA: _______________________________________________________ Contains A, C, G, U, (uracil), it is a single stranded structure, has a ii. RNA: _______________________________________________________ ribose sugar c. The differences in their names: Deoxyribonucleic Acid i. DNA: _______________________________________________________ Ribonucleic Acid ii. RNA: _______________________________________________________ 16) What is the difference between fraternal and identical twins? a. Fraternal: Two different egg and sperm i. Egg and Sperm:_________________________________________________ Different DNA, their DNA is no more similar than two NON-TWIN siblings ii. DNA:_________________________________________________________ b. Identical: One egg and sperm that separates while dividing i. Egg and Sperm:_________________________________________________ Identical DNA ii. DNA:_________________________________________________________ 17) What is the difference between cloning and breeding? An organism that is produced from identical DNA as the ‘parent’ a. Cloning: ________________________________________________________________ ________________________________________________________________________ Organisms that are ‘crossed’ because of their desired traits with the b. Breeding: _______________________________________________________________ ________________________________________________________________________ hope to obtain offspring with the same/similar traits 18) Know the correct order of transferring information in a cell….DNA to RNA to PROTEINS 19) Understand the processes that are involved during the synthesis phase of the cell… Replication…Transcription…Translation 20) General DNA facts… a. What is ‘the genetic code’ It is the sequence of nitrogen basis that determine the SPECIFIC ________________________________________________________________________ traits of an organism ________________________________________________________________________ ________________________________________________________________________ b. What is DNA ULTIMATELY responsible for? DNA is responsible for carrying the genes which ULTIMATELY instruct the ________________________________________________________________________ ribosomes which proteins to make for the organism. ________________________________________________________________________ 21) If there is 22% of Adenine in a DNA molecule… How much Thymine? __22%______ How much Cytosine? __28%_______ How much Guanine? __28%_______ 22) If there is 28% of Guanine in a DNA molecule… How much Thymine? ___22%______ How much Cytosine? __28%_______ How much Adenine? __22%________ 23) Identify the structures below: 1. ____C____ Nucleus 2. ____E____ Amino Acid 3. ____A____ DNA 4. ____D____ Anticodon 5. 6. 7. 8. ____F____ Ribosome ___H_____ tRNA ___G_____ polypeptide, (protein) ___B_____ mRNA g . 1. . e . h . d . a. f . b . c .