10
11
18
23
Redox enzyme;
Methanol catabolic process;
Cell adhesion
Protein binding and targeting to nucleus;
Intracellular protein transport;
Cytoplasmic;
RNA binding through forming protein complex
Catalytic protein that resides in cytoplasm;
Metal ion binding extracellular protein;
Protein binding;
Carbohydrate metabolic process;
Membrane bound;
Enzymatic: acetyl neuraminidase;
Receptor guanylyl cyclase;
Protein binding activity
Pneumovirus attachment glycoprotein G;
Herpesvirus dUTPase;
Neucleopeptide FF receptor
dUTPase
Neuraminidase complex with galactose; Apo dUTPase, binds neuropeptides and activates them
Herpesvirus dUTPase;
CYP2E p450 signature;
Ig-MHC signature;
Poxvirus coat protein
VP1
Porin opacity transport;
Heat labile enterotoxin
B-chain (membrane translocation);
Poxvirus coat protein
VP1 N terminal
(transportation inside neucleus);
Influenza matrix protein M1with membrane and RNA binding ability dUTPase;
Ethanol dehydrogenase
Mitochondrial regulator MTERF, works during replication and forms complex with dsDNA;
Nuclear import and dissociation through RanGTP like mechanism;
Neuclear export
DNA binding
Herpes virus
UL79 like;
PSIBLAST result shows homologous to
UDP epimerase;
RNA biogenesis pathway;
Transcription factor activity homologous to
UDP epimerase
DNA binding groove discovered
24 Metal ion binding;
Catalytic;
Protein bindng;
Redox activity;
P2Y2 signature motif responsible for nucleotide binding;
Somatostatin/
Proteolytic activation;
Deamination/ decarboxylation;
dUTPase;
Neuraminidase activity;
Receptor;
Prottein binding
NCBI CDD showed homology with
EBV LF2 protein dUTPase
Redox reaction;
Cell adhesion and recognition;
DNA BindR and
BindN showed potential RNA binding region;
Initiates a feedback loop
Transport protein
DNA BindR and
BindN showed potential RNA binding region;
TMHMM and
Kyte Dolittle similar to EBV capsid (BCLF1);
CDD showed homology with
Herpes Virus
BTRF1
CDD showed homology with
EBV BCRF1
Capsid protein
ATP binding;
Transport;
Catalysis (?);

27
28
30
31
Carbon metabolism
Hydrolase;
Metal ion binding;
Megatve regulator of inflammatory response
(IL);
Acid phosphatase activity
Protein binding intracellularly;
RNA metabolic process
Protein binding and proteolysis;
DNA binding and transcription;
Regulation of apoptosis
ATP binding;
Cortistatin motif responsible for carbohydrate metabolism;
Coactivator CBP,
PKID responsible for protein binding;
UPTII
(ribonucleoprotein) responsible for nucleotide binding
Tram responsible for ssDNA cleavage;
Neurohypophysial hormone responsible for muscle contraction;
Cleaved adhesion responsible for peptide binding;
BDLF2 like domain responsible for protein trafficking
Envgp36 protein
(HERV/ MMTV) responsible for transmembrane helix;
Dishevelled protein responsible for binding;
Coronavirus protein 7 responsible for protein assembly
Core binding factor, beta subunit responsible for transcription factor and
DNA binding;
Paramyxovirus nonstructural protein C responsible for RNA synthesis;
ROK responsible for
DNA binding
Herpes virus UL92
Clathrin adaptor complex;
GTP binding and nuclear import
Acid phosphatase and metal ion binding
Transmembrane and cytoplasmic domain of human
CD4 characteristic to HCMV UL16-
MICB complex. It causes viral immunoevasion to
NKG2D ligand
Pyogenicity immunoprotein;
RNA pol core binding domain of sigma;
TNFR related death receptor 6 having C terminal
CARD like domain
Galactokinase; EBV BGLF 4 NAD-
TMHMM reaults showed its extracellular
Catalytic;
Neuroregulatory secretory protein
TMHMM shows they are transmembrane
Transmembrane;
Glycoprotein envelop protein
Apoptosis related DNA binding protein;
Transcription factor
TMHMM shows Catalytic;

Kinase activity;
Phosphotransferase activity domain Phosphatase like domain like protein dependent oxidoreductase
33 Oxidoreductase
(quinine as receptor)
Herpes virus UL16 domain/ UL94;
Enzymatic
34
35
42
49
ATP binding and phosphorylation
UL95 family domain;
DNA binding;
Apical membrane 1 signature with hydrophobic domain for envelop;
Oxoisovalerate
(structurally similar to
ATP) dehydrogenase activity
ROK DNA binding;
Paramyxovirus non structural protein C
Enzymatic activity
TetR/CamR family response
EBV BGLF3 like protein
DNA binding and regulation of transcription;
Protein binding and negative regulation of transcription;
Homodimerization activity
Same as 35
Protein binding and protein transport;
RNA binding forming
Herpes virus UL7 like protein;
Transmembrane protein
ROK DNA binding motif;
Dsh in various GTPase
Same as 35
Nuclear import complex by
RanGTP Exportin5
BRRF1 that induces lytic cycle by Traf 2 extracellular localization;
CDD showed homology with
BGLF4;
BGLF4 secretes
IFN3 regulatory factor that causes
IFB3 pathway to downregulate
UL16 interact with UL11 and
UL21 which causes efficient packing;
UL94 is Herpes virus capsid/tegument protein
UL 95 family has enzymatic activity and causes major early gene expression and
DNA replication;
Immunosuppression
Tegument protein
DNA binding tegument protein;
Dehydrogenase activity
Paramyxovirus non structural protein C has both positive and negative effect on mRNA synthesis
DNA binding/
Transcription factor
TMHMM results show transmembrane localization
DNA binding/
Transcription factor
Transcription factor

52
53
55 protein complex
Dehydrogenase activity;
FAD binding for defence response;
Receptor binding
Metal ion binding;
Protein binding;
Redox reaction
DNA binding;
Protein binding for DA replication;
Protein homodimer and important for protein protein interaction;
Influenza matrix protein which has both positive and negative effect on mRNA biosynthesis.
ROK DNA binding;
Dsh for DNA binding;
Pneumovirus nucleocapsid for protein binding;
Aphid transmission protein; bZIP transcription factor
UL73 envelop glycoprotein;
ROK DNA binding;
HTLV tax transcription activator
Pneumovirus nucleocapsid for protein binding;
Paramyxovirus non structural protein C by forming
RanGTP miRNA complex and p53 dependent manner
Tegument protein ORF52 of murine γ-
Herpes virus;
BLRF2 causes
Rta responsive gene transcription
Rrfr family transcription regulation
TetR family
Immediate lytic cycle;
Transcription factor
Glycoprotien;
Transcription factor
Paramyxovirus non structural protein C has both positive and negative effect on mRNA synthesis
Transcription factor