Table e1: Checklist DSM-5 Major NCD
Nikolova 2013 [21]
A. Evidence of significant cognitive decline
A.1. concern of individual,
A.2. substantial impairment
knowledgeable informant
in cognitive performance
or clinician
concluded from seeing a
NINCDS-ADRDA/ NINDSclinician and undergoing
AIREN, TE4D≤35, SKT 9diagnostic procedures
23
NINCDS-ADRDA/ NINDSAIREN, TE4D≤35, SKT 923
NINCDS-ADRDA/ NINDSAIREN, TE4D≤35, SKT 923
NINCDS-ADRDA/ NINDSAIREN, TE4D≤35, SKT 923
NINCDS-ADRDA,
TE4D≤35, SKT 9-23
B. Cognitive deficits
interfere with
independence in everyday
activities
NINCDS-ADRDA/ NINDSAIREN
C. Cognitive deficits do not
occur exclusively in the
context of a delirium
D. Cognitive deficits are
not better explained by
another mental disorder
NINCDS-ADRDA/ NINDSAIREN, and exclusion
criteria
NINCDS-ADRDA/ NINDSAIREN, exclusion criteria
Schneider 2005 [26]
NINCDS-ADRDA, MMSE
10-24
NINCDS-ADRDA
NINCDS-ADRDA,
exclusion criteria
Maurer 1997 [27]
NINCDS-ADRDA, DSM-IIIR
NINCDS-ADRDA, DSM-IIIR, exclusion criteria
DSM-III-R, ICD-10, GDS 36
DSM-III
DSM-III-R, ICD-10,
exclusion criteria
DSM-III, exclusion criteria
DSM-III-R, ICD-10,
exclusion criteria, CT/MRI
DSM-III, exclusion criteria
Kanowski 1996 [29]
NINCDS-ADRDA, DSM-IIIR, BCRS mean 3-5,
ADAS-cog 9-52
DSM-III-R, ICD-10, MMSE
9-26, GDS 3-6
DSM-III, average of SCAG
items 2, 3, 6 and 8 at least
3.5
DSM-III-R, MMSE 13-25
NINCDS-ADRDA/ NINDSAIREN, exclusion criteria,
CT/MRI, labs
NINCDS-ADRDA/ NINDSAIREN, exclusion criteria,
CT/MRI, labs
NINCDS-ADRDA/ NINDSAIREN, exclusion criteria,
CT/MRI, labs
NINCDS-ADRDA/ NINDSAIREN, exclusion criteria,
CT/MRI, labs
NINCDS-ADRDA,
exclusion criteria, CT/MRI,
labs
NINCDS-ADRDA,
exclusion criteria, CT/MRI,
labs
NINCDS-ADRDA, DSM-IIIR, exclusion criteria, CT
DSM-III-R
Haase 1996 [31]
DSM-III-R, GDS 4-5
DSM-III-R, GDS 4-5
Rai 1991 [30]
NINCDS-ADRDA, clinical
assessment
required by inclusion
criteria, verified by various
tests and scales
NINCDS-ADRDA
DSM-III-R, exclusion
criteria
DSM-III-R, exclusion
criteria
NINCDS-ADRDA
DSM-III-R, exclusion
criteria, CT
DSM-III-R, exclusion
criteria
NINCDS-ADRDA
exclusion criteria: other
impairment of cerebral
function
exclusion criteria: other
impairment of cerebral
function
Herrschaft 2012 [22]
Ihl 2011 [23]
Napryeyenko 2007 [24]
Yancheva 2009 [25]
Le Bars 1997 [28]
Oswald 1997 [33]
Weitbrecht & Jansen 1986 [32]
NINCDS-ADRDA/ NINDSAIREN, supported by ADLIS
NINCDS-ADRDA/ NINDSAIREN, supported by ADLIS
NINCDS-ADRDA/ NINDSAIREN
NINCDS-ADRDA/ NINDSAIREN, exclusion criteria
NINCDS-ADRDA/ NINDSAIREN, exclusion criteria
NINCDS-ADRDA
NINCDS-ADRDA,
exclusion criteria
required by inclusion
criteria, supported by
SCAG and Crichton
Geriatric Rating Scale
Table e2: Checklist DSM-5 Mild NCD
Gavrilova 2014 [14]
Grass-Kapanke 2011 [40]
Allain 1993 [41]
Stocksmeier & Eberlein 1992 [42]
A. Evidence of modest cognitive decline
A.1. concern of
A.2. modest impairment
individual, knowledgeable in cognitive performance
informant or clinician
Winblad consensus
CAMCOG<10th percentile
criteria [4]
for age, sex and
educational level
subjective complaint of
at least one standard
cognitive impairment,
deviation below
perceived as decline from normative group in at
former level of
least one cognitive test
functioning
self-reported, perceived
more than one standard
cognitive impairment
deviation below young
persons in word list recall
test
self-reported, perceived
below 16th percentile in
cognitive impairment
test for concentration and
memory
B. Cognitive deficits do
not interfere with capacity
for independence in
everyday activities
IQCODE mean score <4
C. Cognitive deficits do
not occur exclusively in
the context of a delirium
D. Cognitive deficits are
not better explained by
another mental disorder
inclusion criterion: intact
activities of daily living,
non-demented
exclusion criteria: any
other cognitive or mental
disorder
exclusion criteria: any
other cognitive or mental
disorder
exclusion criteria: any
other cognitive or mental
disorder, MRI scan
exclusion criteria: any
other cognitive or mental
disorder
in-/exclusion criteria, nondemented (supported by
MMSE 27-28)
in-/exclusion criteria: any
other cognitive or mental
disorder
in-/exclusion criteria: any
other cognitive or mental
disorder
in-/exclusion criteria, nondemented
in-/exclusion criteria: any
other significant cognitive
or mental disorder
in-/exclusion criteria: any
other significant cognitive
or mental disorder
Table e3: Checklist DSM-5 NCD without clear distinction between mild and moderate NCD (criteria that may indicate mild or major NCD printed in italics)
Gräßel 1992 [34]
Halama 1988 [35]
Hofferberth 1994 [36]
Schubert & Halama 1993 [37]
Israël 1987 [38]
Wesnes 1987 [39]
A. Evidence of modest or significant cognitive decline
A.2. modest or
A.1. concern of
individual, knowledgeable substantial impairment in
cognitive performance
informant or clinician
cognitive decline, i.e.
concluded from seeing a
current IQ (derived from
clinician and undergoing
short term storage
diagnostic procedures
capacity) < pre-morbid IQ
(derived from verbal
intelligence test)
cognitive impairment
concluded from seeing a
documented by cognitive
clinician and undergoing
testing and rating scales
diagnostic procedures
Blessed Dementia Rating
concluded from seeing a
Scale Part A: 0 – 16 and
clinician and undergoing
Part B 9.5 – 30.5; SKT
diagnostic procedures
scores supportive of
dementia
at least 10 points on C.I.
concluded from seeing a
Scale
clinician and undergoing
diagnostic procedures
MMSE 20-26
self-reported memory
complaints
B. Cognitive deficits do
not interfere with capacity
for independence in
everyday activities
no criterion
C. Cognitive deficits do
not occur exclusively in
the context of a delirium
D. Cognitive deficits are
not better explained by
another mental disorder
exclusion criteria: any
other neurological or
psychiatric disorder
exclusion criteria: any
other neurological or
psychiatric disorder
no criterion
exclusion criteria: other
significant disorders
no criterion
Crichton Geriatric
Behavioural Rating Scale
at least 14, but no item
rated higher than 3
"mild impairment of
everyday functioning"
was required, but no
clear statement of
influence on idependence
exclusion criteria: other
neurological or
psychiatric disorders,
pronounced sensory or
motor disturbances
exclusion criteria: any
other neurological or
psychiatric disorder
exclusion criteria: any
significant acute or
chronic disease
exclusion criteria: any
neurological or
psychiatric disorder that
could cause cognitive
impairment
exclusion criteria: other
possible reasons for
cognitive impairment
exclusion criteria: other
neurological or
psychiatric disorders,
intellectual deterioration
of other origin
exclusion criteria: any
other neurological or
psychiatric disorder
exclusion criteria: any
significant acute or
chronic disease
exclusion criteria: any
neurological or
psychiatric disorder that
could cause cognitive
impairment
concluded from seeing a
clinician and undergoing
diagnostic procedures
no criterion
no criterion