Medical Evaluation of Surgical Risk. Johns. Katelyn Rogers. 04.13.10. Role of Primary Care MD Estimate surgical risk from H&P, appropriate lab and x-ray Diagnose and manage medical problems that contribute to morbidity and mortality Interoperate and Postoperative Death First 48 hours – 0.3% mortality When does the 0.3% occur: 10% - induction of anesthesia 35% - operatively 55% - postop in first 48 hours ICSI- develop patient care guidelines for different conditions as well as preoperative care guidelines. Interoperative and Postop Death First 48 hours Causes – 15% each Failure to maintain adequate ventilation Aspiration Arrhythmia Drug induced myocardial depression Hypotension from blood loss Surgical Risk Composed of: Physical status of patient – as primary care MDs we have control over this one. Surgical factors – not our role to tell them which procedure. Yet they respect what you have to say. Anesthesia factors Physical Status of Patient ASA Physical Status Scale Developed in 1940’s, modified since Relies on accurate H & P (from primary care MDs) Estimates surgical risk More recent studies show good correlation with non-cardiac mortality ASA Physical Status Scale: this is something the anesthesiologists write Class 1: A normally healthy individual Class 2: Patient with mild systemic disease mild HTN for eg. Class 3: Patient with severe systemic disease that is not incapacitating RA, HD in past not active now. Class 4: Patient with incapacitating systemic disease that is a constant threat to life. CHF, angina. Class 5: A moribund patient near death E: Added to any class patient with emergency surgery Big difference is btwn Class 3 & 4. People with systemic dxs that aren’t incapacitating do fine. Those with incapacitating systemic dx are at a greater risk for mortality. This is impt to evaluation in the H & P. Emergency surgery also tends to double the risk. Cardiac Risk Factors in Patients Undergoing Non-cardiac Surgery Preop is done by Cardio docs if a cardiac surgery. Physiology of peri-operative period Disturbance of cardiac performance Increased cardiac 02 demand (tachycardia) Diminished O2 supply (hypoxemia) Anesthetic agents have two major effects: (TQ) 1) Myocardial depression (all) 2) Arrhythmogenic properties -Pre-op arrhythmia- 0.4% risk of serious arrhythmia operatively (pretty low) -Known pre-op heart disease- 3.9% risk of serious arrhythmia operatively -Therefore: Serious operative arrhythmias more closely asstd w underlying heart dx than pre-op arrhythmias alone. It is more impt the genl status of the heart! It’s okay to have some PVCs for eg. 1 Goldman’s Assessment Score Developed to assess cardiac risk of non-cardiac surgery After analysis of various cardiac conditions, point values were assigned to various cardiac states Condition: Points: S-3 gallop or JVD 11 Myocardial infarction in past 6 months 10 PVC’s, more than 5/minute 7 Rhythm other than sinus 7 Age over 70 years 5 Emergency operation 4 Intrathoracic, abdominal or aortic surgery 3 Important aortic stenosis 3 Poor general medical condition 3 Class (Points) I ( 0-5 ) II ( 6-12 ) III (13-25) IV (over 26) Morbidity 0.7% 5% 11% 56% Mortality 0.2% 2% 2% 22% Class III: watch post op! Class IV: Risk overall for surgery! Look at the overall characteristics rather than the numbers. Gallop is a sign of myocardial dysfxn aggrevated by anesthesia arrythmias. Also susceptible to fluid shifts. Surgical Factors Organ involved Extent of disease Skill of surgeon Length of surgical procedures Facilities – places that do many surgeries tend to be better at it. Anesthesia Factors Spinal vs. general (data indicates that they are about the same as far as safety) Risk of intraoperative hypotension same CHF may be worsened by general anesthesia Gauthier (1983)- elderly patients with hip surgery showed similar mortality Mortality Related to Anesthesia (no statistical difference, both are very safe) ASA Spinal General 1 1: 100,000 1: 25,000 2 1: 3,500 1: 1.000 3 1: 400 1: 350 4 1: 35 1: 46 5 1: 16 1: 24 None of above are statistically significant Summary of Surgical and Anesthesia Factors (Goldstein) Poor physical status Race (non-whites) Poor physical fitness Long duration of anesthesia and surgery Cardiac disease (angina, CHF) Surgery of vital organs Extremes of age Complex surgery The adult male Emergency surgery Depression or anxiety – You can help with this. Help feel Lack of skill, infrequent performance and excessive confident. aggressiveness of surgeon What Isn’t on Goldman’s Scale? Hypertension: several studies show no increased risk if diastolic is less than 110 Stable angina: threefold increase in cardiac complicationsbut no overall increase in death Notes Murmurs- risk highest for symptomatic aortic stenosis (8X). Mitral regurgitation risk (3X). If not symptomatic than not sig. Post-op MI’s (what people worry about!) 60% occur in first 3 days 70% occur by days 4-6 50% are silent The mortality overall is 50-70% Hypokalemia Serum K should be over 3.0 (normal is over 3.5) If on digitalis should be over 3.5 2 Anemia Tissue oxygen supply variables: 1) cardiac output 2) hemoglobin 3) A-V oxygen saturation % difference Remember! Normal blood volume is more important than the actual hemoglobin value. The hemoglobin should be over 10 if significant blood loss is expected during surgery. BV is impt bc upon administration of anesthetic they can become severely hypotensive. How do you know if they have low blood volume? You have to lose ½ your blood vol to become hypotensive, so how would you test it? Capillary refill will help you see how well they are perfusing. Another is postural BP checks. Lying down may have normal pressure, stand them up may severely decrease their BP. If this happens then the BV is low! Basic Rules for Elective Surgery (Good Summary!) 1) No surgery within 6 months of a M.I. 2) No surgery in the patient has active CHF or its’ signs (crackles, S3). 3) Stable angina does not carry an increased risk, unstable angina does. 4) Hypertension with a diastolic under 110 does not carry an increased risk. 5) Pre-op arrhythmias are more significant if associated with underlying heart disease. 6) Potassium over 3.5 if on digitalis, 3.0 if not. 7) The hemoglobin should be over 10.0 in a patient with coronary artery disease,over 8.5 in other patients. 8) From a medical standpoint, spinal anesthesia is not significantly safer than general anesthesia. They are both safe. 9) In emergency surgery you have to weigh the benefits and the risks, there are no firm rules! Should We Clear This Patient For Surgery? (KNOW THESE!) 1) 45 year old male scheduled for an elective hernia repair. He had a myocardial infarction 5 months ago and has been free of cardiac problems since. Yes or No 2) 54 year old female with a blood pressure of 166/98 is scheduled for an elective hysterectomy. Yes or No 3) 65 year old female scheduled for a mastectomy for cancer. She denies shortness of breath but has a S3 gallop and bilateral lung crackles. Yes or No 4) 78 year old male is scheduled for a lumbar laminectomy and has a hemoglobin of 9.8. He has a known chronic anemia and does not have heart disease. Yes or No 5) A 66 year old male on Lasix (furosamide) has a potassium of 3.4 (normal 3.5-5. He is scheduled for knee surgery and is not on digitalis. Yes or No 6) 89 year old female with mild CHF, stable angina, hemoglobin of 8.2, chronic renal failure with a creatinine of 2.8, and a mild myocardial infarction about 5 months ago, is scheduled for a cataract extraction. Yes or No Order UA, electrolytes if on dialysis, EKG over age of 50, and hemoglobin are all impt tests to do before a surgery. Questions: 1. What is the most important factor for evaluating the physical status of a patient for surgery? 2. When does surgical mortality increase, in which classes of the ASA physical status scale and what characteristics would be seen? 3. What are the two major risk effects of anesthesia? 4. T/F. Serious preoperative arrhythmias are more closely associated with underlying heart disease than pre-op arrhythmias alone. 5. T/F. Hemoglobin value is more important than a normal blood volume. Answers: 1. 2. 3. 4. 5. An accurate H & P by the primary care MD. Between class III & IV. Once the patient has an incapacitating systemic disease. Myocardial depression and arrythmogenic properties. T F Case Answers: Answer to #1 No- remember the 6 month rule. The risk of cardiac complications is highest in the first 6 months after an MI. If incarcerated hernia then maybe have to do it. Answer to #2 Yes- the diastolic should be under 110 for surgery. Answer to #3 No- the presence of congestive heart failure or its’ physical signs carries a high risk of postop CHF and pulmonary edema. Answer to #4 Yes- since his anemia is chronic, we can assume his blood volume is normal. Blood volume is more important than the absolute hemoglobin. The blood loss from a laminectomy should be minimal. Answer to #5 Yes- his potassium is over 3.0 and he is not on digitalis. Answer to #6 Yes- when it comes to cataract surgery done under local anesthesia, almost every patient is a candidate. The only real contraindication is a bad cough which can elevate intra-ocular pressure. 3