Job Description and Person Specification Last updated: <date> JOB DESCRIPTION Post title: Research Fellow Academic Unit/Service: Human Development and Health Faculty: Medicine Career Pathway: Education, Research and Enterprise (ERE) *ERE category: Research Pathway Posts responsible to: Professor of Genomics Posts responsible for: Junior members of staff and postgraduate students Post base: Office-based Level: 4 Job purpose This position will support research into medical genomics and will specifically underpin the strategic relationship formed to advance the Wessex Genomics Hub (UoS, UHS and SDH). Key accountabilities/primary responsibilities % Time 1. Investigate aspects of genomics variation with regards to clinical characteristics 25 % 2. Manage large scale NGS datasets including assessment of quality and platform evaluation. 20 % 3. Develop and validate novel methods for medical genomics 10 % 4. Prepare drafts of manuscripts for publication and reports for multidisciplinary meetings. Present work at local, national and international meetings 20 % 5. Contribute to undergraduate and postgraduate education 20% 6. Communicate with collaborators effectively 5% Internal and external relationships Human Genetics and Genomic Medicine Group, HDH Academic Unit Wessex Genomics Hub (WISH Lab) Wessex GMC and local GeCIPS Special Requirements Excellent programming and data analysis skills are essential, as is experience of working with large-scale NGS data in a clinical setting. Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon completion of PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given. PERSON SPECIFICATION Criteria Essential Desirable Qualifications, knowledge and experience PhD in a relevant subject (e.g. Genomics, Bioinformatics) or equivalent professional qualifications and experience Success in attracting external funding How to be assessed Application/CV Firm grounding in statistical methods. Strong track record in preparing publications and other written materials. Previous experience in working with large scale (empirical and/or simulated) datasets. Experience in working with human genome sequence data. Experience analysing exome and targeted NGS data. Experience of development NGS bioinformatics analytical pipelines. Experience of interrogation and interpretation of data in the context of medical genetics. Excellent scripting/programme skills (R, Perl, C, C++). Knowledge of annotation, assembly and mapping tools Familiarity with online human gene resources and databases Planning and organising Effective time management and project planning/scheduling skills Appreciation of QA issues in diagnostics Attention to detail and ability to work to tight timelines Demonstrable project management and organisational skills Excellent report writing skills Scrupulous attention to detail and data quality issues Problem solving and initiative Ability to use own initiative and solve analytical problems Ability to interpret results given biological hypotheses Ability to generate independent Document1ERE Level 4 – Research Pathway – Research Fellow 2 ideas and directions of new research Document1ERE Level 4 – Research Pathway – Research Fellow 3 Management and teamwork Able to work as an efficient and communicative member of the team and be expected to share expertise with other group members Experience in supervising and guiding junior research staff Capacity to contribute to internal training and teaching as required Experience working within a diverse interdisciplinary team Communicating and influencing Ability to communicate effectively with collaborators both internally and externally Able to foster excellent working relationships with colleagues Excellent communication skills, both written and oral Other skills and behaviours A desire to achieve excellence in research Special requirements Document1ERE Level 4 – Research Pathway – Research Fellow 4 JOB HAZARD ANALYSIS Is this an office-based post? ☒ Yes If this post is an office-based job with routine office hazards (eg: use of VDU), no further information needs to be supplied. Do not complete the section below. ☐ No If this post is not office-based or has some hazards other than routine office (eg: more than use of VDU) please complete the analysis below. Hiring managers are asked to complete this section as accurately as possible to ensure the safety of the post-holder. ## - HR will send a full PEHQ to all applicants for this position. Please note, if full health clearance is required for a role, this will apply to all individuals, including existing members of staff. ENVIRONMENTAL EXPOSURES Occasionally Frequently Constantly (<30% of time) (30-60% of time) (> 60% of time) Outside work Extremes of temperature (eg: fridge/ furnace) ## Potential for exposure to body fluids ## Noise (greater than 80 dba - 8 hrs twa) ## Exposure to hazardous substances (eg: solvents, liquids, dust, fumes, biohazards). Specify below: Frequent hand washing Ionising radiation EQUIPMENT/TOOLS/MACHINES USED ## Food handling ## Driving university vehicles(eg: car/van/LGV/PCV) ## Use of latex gloves (prohibited unless specific clinical necessity) ## Vibrating tools (eg: strimmers, hammer drill, lawnmowers) PHYSICAL ABILITIES Load manual handling Repetitive crouching/kneeling/stooping Repetitive pulling/pushing Repetitive lifting Standing for prolonged periods Repetitive climbing (ie: steps, stools, ladders, stairs) Fine motor grips (eg: pipetting) Gross motor grips Repetitive reaching below shoulder height Repetitive reaching at shoulder height Repetitive reaching above shoulder height PSYCHOSOCIAL ISSUES Face to face contact with public Lone working ## Shift work/night work/on call duties Document1ERE Level 4 – Research Pathway – Research Fellow 5