Editor Profile
Monica Rinaldi
Institute of Translational Pharmacology
Department of BioMedicine
National Research Council, Italy
Contact
Institute of Translational Pharmacology (IFT)
National Research Council (CNR)
Via Fosso del Cavaliere 100
00133 Rome, Italy
Phone: (+39) 0649934219
Fax: (+39) 0649934257
E-mail: monica.rinaldi@ift.cnr.it
Commitments and Accolades
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Editor (Invited Handling Editor) for the volume “DNA Vaccines”, in 'Methods in Molecular Biology' series
published by Humana Press, Springer publishing group (2012-present)
Member, Board of Editors, Novus International Journal of Biotechnology & Bioscience, (Novus Scientia
Journals, (2012-present)
Associate Editor, Journal of Alzheimer Disease, (IOS Press publication) (2011)
Member, Institute Committee, Institute of Translational Pharmacology, CNR, (2010-present)
Appointed by the Director, Institute of Translational Pharmacology, CNR, in the Commission of reviewers
for the selection of Technicians, Young Investigators, Senior Investigators, Researchers (2010-present)
Appointed by the Board of Directors, CNR, in the list of internal expert for the composition of committees
in the national process of recruiting staff researcher and technologist (2009-present)
Member, Institute Committee, Institute of Neurobiology and Molecular Medicine, CNR, (2009-2010)
Appointed by the Director, Institute of Neurobiology and Molecular Medicine, CNR, in the Commission of
reviewers for the selection of Young Investigators, Senior Investigators, Researchers (2003-2009)
Current Research
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In vivo naked gene transfer into muscle
Development of specific multigenic plasmid vectors
Pre-clinical protocols by systemic delivery of recombinant proteins in animal models of human
diseases.
Anti tumor DNA vaccines in indolent B cell Lymphoma and colon cancer
Pre-clinical protocols of genetic immunization against tumor antigens
Combined therapeutic protocols (vaccination+immunotherapy+chemotherapy)
Development of innovative vaccine formulations for anticancer therapy and/or prevention, intended for
clinical application
Biography
Monica Rinaldi was born in 1964 in Rome, Italy. After graduating with full honours in Biology at the University
of Rome "La Sapienza", she obtained a Ph.D. in Biotechnology. From 1995 to 2000 she was a Post-Doctoral
Fellow in Molecular Medicine at the Institute of Neurobiology and Molecular Medicine, National Research
Council (CNR), ITALY. She was appointed as Assistant Professor of General Pathology at University
Campus Bio-Medico of Rome, School of Medicine (1996-2001), and Professor of Molecular Biology at
University Campus Bio-Medico of Rome, School of Engineering, Degree in Biomedical Engineering (19992000). Since 2001 she is Research Scientist at the Department of BioMedicine, CNR. She is Head of
Laboratory of Medical Biotechnology at the Institute of Translational Pharmacology (IFT), CNR. Dr. Rinaldi is
the author of more than 50 peer reviewed scientific publications, including original research articles, book
chapters and invited reviews. She is co-inventor of U.S. patents (USPTO) and Principal Investigator of
several grants related to biotechnology applications in medicine. She is peer reviewer for several scientific
journals. Her major field areas are Molecular Pathology, Experimental Oncology, Immunotherapy and
research interests focus on the pre-clinical development of innovative drug formulations and protocols for
advanced therapies (gene therapy and DNA vaccination).
Selected Recent Publications
Epitope-driven DNA vaccine design employing immunoinformatics against B-cell lymphoma: a biotech's
challenge
Iurescia S, Fioretti D, Fazio VM, Rinaldi M
Biotechnology Advances; volume 30; pages 372-383; Published: 2012
Design and pre-clinical development of epitope-based DNA vaccines against B-cell lymphoma
Iurescia S, Fioretti D, Fazio VM, Rinaldi M.
Current Gene Therapy; volume 11, issue 5; pages 414-22; Published: 2011
Genetic immunization with CDR3-based fusion vaccine confers protection and long-term tumor-free survival
in a mouse model of lymphoma.
Iurescia S, Fioretti D, Pierimarchi P, Signori E, Zonfrillo M, Tonon G, Fazio VM, Rinaldi M.
Journal of Biomedicine and Biotechnology; volume 2010; Published: 2010
Anti-tumor immunity induced by CDR3-based DNA vaccination in a murine B-cell lymphoma model
Rinaldi M, Fioretti D, Iurescia S, Signori E, Pierimarchi P, Seripa D, Tonon G, Fazio VM.
Biochemical and Biophysical Research Communications; volume 370; pages 279-84; Published: 2008