Curriculum Vitae
Mathematics and Computer Science
Fayetteville State University, NC
Name: Dr. Frank Nani
Title: Associate Professor
Department: Mathematics & Computer Science
Phone:910 672 1793
Email: fnani@uncfsu.edu
Program Area: Mathematics
Status: Full Time
0. GOALS and OBJECTIVES:
(i) Development of innovative Regional and National Mathematical Modeling
Programs and Workshops at the Undergraduate and Graduate Levels.
(ii) Development of Mathematical and Statistical Evidence-Based-Medicine
Programs for Duke Medical Doctor interns at the AHEC.
(iii) Derivation of relevant mathematical criteria to predict with optimal precision
the prognosis and the efficacious physiologic outcomes for cancer patients
during therapy.
1. Academic Degrees
Degree
Date
PhD
Nov. 1998
MSc.
Nov. 1985
B.Sc.
June 1980
Major
Applied
Mathematics
(Mathematical
Medicine,
Computational
Immunology , AIDS
and Cancer
Therapy)
Theoretical Physics
(Solving Einstein
Gravitational Field
Equations to predict
fate of the universe)
Physics(Honors:
University
Departments of
Mathematics and
Cross Cancer
Institute University
of Alberta ,
Edmonton
CANADA
Theoretical Physics
Institute, University
of Alberta,
Edmonton, Alberta
CANADA
U.S.T. , Kumasi
1
Nuclear /Atomic)
GHANA
2. Fields of Expertise : Applied Mathematics, Theoretical Physics, Cancer Chemotherapy
Mathematical Medicine, Computational Immunology, Evidence-Based-Medicine
3. Professional Experiences/Dates:
 (2002 August –Current )
Position/Title : Associate Professor of Mathematics
Institution
:
Fayetteville State University
Department of Math & Computer Science
1200 Murchison Road
Fayetteville NC

1995 August-2002 July
Position/Title : Lecturer /Research Associate
Institution
:
Department of Mathematics, University
of Alberta , Edmonton .

1994 September-August 1995
Position /Title : Lecturer
Institution
:
Grande Prairie Regional College
Department of Science and Technology
Grande Prairie Alberta, Canada .

1981 November- 1982 December
Position /Title : Head of Department
Institution
:
Presbyterian Boys Sixth Form College
Legon , Accra Ghana.

1980 June –1981 November
Position/Title: National Service Scientific Research Officer
Theoretical Nuclear Physics Division
Institution : Ghana Atomic Energy Commission
P.O. Box 79 , Legon Ghana
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Major Duties and Responsibilities: Nuclear Research
4. Dr. Nani’s Current Graduate Students and their Research
Name of Grad.
Research Topic
Program Start Date
Student
Projected Time for
Completion
Sarah Johnson
Jan. 2006
Sept 2008
Academic Standing
and Progress of
Student
Good
Jan. 2006
Sept. 2008
Good
Jan 2006
Sept. 2008
Good
Sept. 2006
June 2008
Good
Rebecca Smoak
Luis Hercilla
Albert Chan
Mathematical
Modeling of Cancer
Radiotherapy
Mathematical Models
in Genetics
Derivation of
Prognostic Criteria for
immunotherapy of
AIDS
Computer modeling of
Brain Cancer Therapy
5. Services to University, College, Department:
(i) Chair of the graduate committee for MCS Department
(ii) Coordinator for the graduate program of MCS Department
(iii) Member of Academic Affairs Committee of CBAS
(iv) Member of Industrial Math. Committee for MCS Department
6. Services to Public Schools:
(i) Judge for Forensics Tournament
on March 2004
at
Cape Fear High School
(ii) Helped Loyd E. Auman Elementary School for the
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Battle of the Books Tournament at FSU on Feb 08 2005
(iii) Judge for Forensics Tournament at
on Jan 20 2004
71st High School
7. SCIENTIFIC PUBLICATIONS AND BOOKS:
(1)Generalized Newman-Unti Expansions. PHYSICS LETTERS Vol. 113A
Garry Ludwig).
1 pp11—16 Nov 1985.(refereed)(co-author: Dr.
Comments: This publication provides a generalization of a mathematical method used by physicists to solve the classical
Einstein Gravitational Field Equations. It provides a basis for the search for gravitational waves predicted by the Einstein Field
equations. This paper is of outstanding merit and it is now part of the NASA /Smithsonian collection.
(2) [BOOK] Generalized Solutions to the Einstein Gravitational Field Equations. Published by University of Alberta
1987.
Comments: This book is for reference only at the National Library of Canada.
The book provides generalized geometric Newman-Unti type solutions to the classical
Gravitational Field Equations. Other known solutions such as the Schwarzchild, Godel , Kerr, Vaidya and
many others can be systematically obtained from my solutions. Thus my solutions provides a more compact
and unified geometric solution to the classical Einstein gravitational field equations. The significance of this
book is that it provides the mathematics for the behavior of gravitational waves.
(3) Modeling and simulation of Drug Delivery to the Central Nervous System. BIOMEDICAL MODELING
1992 pp351—367 (refereed (coauthor: Dr. M.N. Oguztorelli)
and SIMULATION IMACS
Comments: This paper was presented at the international 1991 IMACS Dublin conference on several
cutting edge applied mathematical research techniques and technologies . This publication was
chosen as one of most outstanding works on Biomedical Modeling and Simulation. The proceedings
containing this paper is now available at the National Library of Medicine and also at the Library of Congress.
The rights to the publication may be owned by Defence Agency ,DTIC . The paper provides mathematical models and clinically
feasible computer simulations of the physiological mechanisms of administering therapeutic drugs to the Brain and the entire
Central Nervous System. This is the first model internationally to involve drug transport vesicles
Stealth Liposomes , monoclonal antibodies , anti-cancer drugs and radio-nuclides. Stealth liposomes are now used for treament of
ovarian cancer. The models are based on clinical research of Dr. Teresa Allen at Department of Pharmacology , University of
Alberta , Canada.
(4) Textbook: Mathematical Principles of Clinical Medicine 2006 (author : F. Nani
to be published by Hindawi Publishing Corporation).
Comments: This book will be released next year pending publisher negotiations. The book is intended for graduate
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Students and medical researchers all over the world who are doing research in computational immunology, Cancer Therapy,
Pharmacology and HIV/AIDS. This book contains chapters on Mathematical Pharmacology, Mathematical
Chemotherapy, Mathematical Immunotherapy, and lots of investigative computer simulations. Explicit mathematical algorithms are
provided for the computer simulations. Cell-cycle phase specificity and cell cycle transition times are incorporated in the
chemotherapy and immunotherapy models.
(5) Modeling and Simulation of Rosenberg-Type Adoptive Cellular Immunotherapy .IMA Journal of Mathematics
Applied in Medicine .1994 vol. 11 pp104—147. Oxford University Press .(refereed) (co-author: Dr. M.N. Oguztorelli)
Comments: This paper is of immense international importance. It is one of the publications selected for the National Library of
Medicine. In the article Computational Immunology : The Coming of Age, published in Immunology and Cell Biology 2002 vol. 80
, Petrovsky and Brusic cited this publication as one of the works that pioneered the emerging field of Computational Biology. In
particular in the state-of –the –science April 13 2000 Joacchim Gruber ,Medline Survey of Models of Immune Systems involving
Differential Equations, this model was among the chosen best worldwide. The website for this is
http://www.lymenet.de/literatur/immundif.htm. This paper was requested by Dr. Alan Perelson of Los Alamos National Laboratory
USA, Dr. J. V. Klavins Chairman of the Department of Pathology Catholic Medical Center New York USA, Dr. Mohan Chelladurai
Department of Physiology Providence Hospital Southfield MI, Dr. Laurence Chaperot Grenoble Blood Transfusion FRANCE, Dr. Paul
Heuschling Neuroimmunologie & Inflammation
LUXEMBOURG, Dr. Petr Jilek Faculty of Pharmacy CZECH REPUBLIC, Dr. Pedro C. Rodriguez Laboratorios de Antcuerpos y
Biomodelos Experimentales Santiago de Cuba CUBA , Dr. Judah Folkman USA and many more around the world.
CITATIONS: 5 Google count
(6) Modeling and Simulation of Chemotherapy of Hematological and Gynaecological Cancers . IMA Journal of
Mathematics Applied in Medicine.1999 vol 16 pp39—91 Oxford University Press (refereed)(coauthor: Dr. M.N.
Oguztorelli)
Comments: This paper is also selected for the National Library of Medicine in Bethesda, Maryland.
This publication was included in a workshop organized by the University of Massachussetts Medical School.
The publication is extremely useful to medical doctors who are involved in organizing therapies for cancer
patients all over the world. Explicit pharmacological drug protocols and patients physiological parametric configurations are
incorporated in the models.
CITATIONS: 4 Google count
(7) A Mathematical Model for Cancer treatment by Immunotherapy
Mathematical Biosciences 163 pp159—199 2002(refereed)(coauthor: Dr H.I. Freedman)
Comments: This publication is a classical example of computational immunology. Theoretical
Criteria are presented for the cure of cancer by immunotherapy. It provides a rational basis for elimination
of useless cancer therapeutic protocols without harming the cancer patient.
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CITATIONS: 11 Google count
( 8) A Chemotherapy Model for the Treatment of Cancer with Metastasis
Mathematical and Computer Modeling 36 pp773—803 2002 (refereed)
(co-authors: S. Pinho , H.I. Freedman)
Comments: This publication was a result of summer 2001 research with a Brazilian
Post –Docterate fellow called S Pinho. This publication provides theoretical foundations for
the treatment of cancer that has spread to other regions of the human anatomy.
CITATIONS: 1 Google count
(9)[BOOK] Mathematical Models of Chemotherapy and Immunotherapy 1999.
Comments: This book is published by the University of Alberta Printing Press
And is for reference only at the National Library of Canada
(10)[BOOK] Lattice Dynamics and Computation of Specific Heat for Transition Metals 1980
Comments: This book was published by the University of Science and Technology, Kumasi
Ghana. It is in the archives of the Ghana Atomic Energy Commission.
(11) A Mathematical Model for Cancer treatment by Chemotherapy (preprint)
To appear in Mathematical Biosciences (refereed)(coauthor: Dr H.I. Freedman)
Comments: This publication contains theoretical calculations and criteria for the scenarios of
Cancer annihilation, cancer recurrence, and cancer persistence during chemotherapy.
CITATIONS: 1 Google count.
8. Invited Speaker Presentations:
(i) Mathematical Principles of Chemotherapy of Human Solid Tumors:
Invited Speaker: Conference on Differential Equations and Applications
Melbourne, Florida August 5 2005
(ii) Mathematical Modeling of the Therapeutic Outcomes of Cancer Therapy:
Cancer remission, Cancer Recurrence, and Cancer Annihilation.
Jacksonville Florida , November 14 2003
(iii) Is there a cure for Brain Tumors ?: A Mathematical Point of View:
Fayetteville State University April 2002
9. Research Proposals/Grants:
(i) FICAMS HBCU Grant from USA Department of Education worth $225,000
Co-PI with Dr. Erin White and Dr. Dan Okunbor September 2006
(ii) FSU Mini-grant $7,000.00 June 2004
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10. Contributions to Undergraduate Research in the United States:
(1) NC-LSAMP Regional Undergraduate Research Conference , Charlotte NC March 19 2004
Student Mentored: Tiffany Gorseth, Fayetteville State University
Research Topic: Mathematical Modeling of HIV Pathology
(2) Moderator Undergraduate Presentations MAA South Eastern Section , Meredith College Raleigh
NC March 11 , 12 2005
(3) Workshop Organizer and Moderator on Cancer and Differential Equations ,
Jacksonville University
Florida November , 14 2003
(4)National Conference On Undergraduate Research (NCUR) April 15-17 2004
Student : Jeff Woodley, Jacksonville University
External Mentor: Dr. Frank Nani
Topic: Modeling and Computer Simulation of Chronic Intravenous Drug Infusion for Cancer Chemotherapy
(5)National Conference On Undergraduate Research (NCUR) April 15-17 2004
Student : Kevin M. Moeller , Jacksonville University
External Mentor: Dr. Frank Nani
Topic: Analysis and Simulation on Cancer Chemotherapy involving Michaelis – Menten Drug Kinetics
(6)NC-LSAMP Regional Undergraduate Research Conference , Greensboro NC March 21 2005
Student Mentored: Monique Saunders, Fayetteville State University
Research Topic: Mathematical Modeling of Breast Cancer Chemotherapy
(7) NC-LSAMP Regional Undergraduate Research Conference , Fayetteville NC March 24 2006
Student Mentored: James King, Fayetteville State University
Research Topic: Mathematical Modeling of Hepato-Cellular Carcinomas( Liver Cancer)
(11) SCIENTIFIC PARTICIPATION
(i) Reviewer for : Journal of Mathematical and Computer Modeling
(ii) Participation in the Development of Evidence –Based –Medicine Program for Duke University
Medical School Interns at the AHEC Medical Clinic , Fayetteville NC.
(iii) Editorial Review Board Member for Scientific Journals International
(12) MEMBERSHIP OF SCIENTIFIC ORGANIZATIONS
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(i) MAA
(ii) AMS
(iii) AAAS
(13) AWARDS
(i)NC- LSAMP Minority Research Mentor Award November 01 2003
Presented by : Dr. Bertha Miller, Program Director Fayetteville State University
(ii)NC- LSAMP Minority Research Mentor Award October 16 2004
Presented by : Dr. Juliette B. Bell , Program Director Fayetteville State University
(iii) NC- LSAMP Minority Research Mentor Award October 22 2005
Presented by : Dr. Juliette B. Bell , Program Director Fayetteville State University
(iv) NC- LSAMP Minority Research Mentor Award October 26
2006
Presented by : Dr. Daniel Okunbor , Program Director Fayetteville State University
(v) FSU-RISE Research Award March 23 2007
Presented by: Dr. Sherrice Allen, Program Director Fayetteville State University Director
(vi) DELTA CHI FRATERNITY Teaching Award, Alberta Canada Chapter February 01 2000
Presented by: Piotr Zielinski , Coordinator
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