Research Narrative I have devoted the greater part of my research career to the three “i”s: inverse problems, integral equations, and ill-posed problems. Most classical problems in the mathematical sciences are direct problems. Direct problems typically involve determining exterior effects of internal causes or predicting future forms of present conditions. In a sense one can say that in direct problems the orientation is usually outward-directed or prospective, and direct problems are almost always analyzed using the mathematical methodology designed to model temporal evolution or spatial distribution, that is, differential equations. A canonical example of a direct problem is the determination of future temperature distributions in a body given its present temperature distribution (“initial condition”) and details of its interaction with its environment (“boundary conditions”). But many important problems in current science and technology are inverse problems. In these problems the point of view is typically introspective or past-directed. Inverse problems often involve determination of interior structure from exterior measurements (think: medical imaging, such as Computed Tomography, Magnetic Resonance Imaging, and Ultrasound), or “post-diction” (think: assessment of pre-historical topography or paleoclimatology). The inverse heat conduction problem, which requires the reconstruction of past temperature distributions of a body given its present temperature distribution, is an iconic example of an inverse problem. It should come as no surprise, at least to those who can recall a bit from their first calculus course (hint: differentiation and integration are inverse processes), that since direct problems are usually modeled by differential equations, many inverse problems are modeled by integral equations. Solving inverse problems modeled by integral equations generally requires determining fine features of an unknown function given gross information obtained through a process of smoothing or integration (as occurs in all physical measurement processes). What makes these inverse problems interesting - and difficult is that they are often ill-posed: an inverse problem might not have a mathematical solution (at least not in the conventional sense); it could have many (even infinitely many) solutions; and – most important for practicing scientists – solutions of inverse problems can be unstable. Instability means that tiny changes in the parameters or data of an inverse problem can result in solutions that are wildly out of control. Taming such mathematical instability is a major technical challenge. I have researched approximation methods for inverse and ill-posed problems modeled by integral equations (or more generally, operator equations) for more than three decades and have made several contributions to these areas which have been termed “fundamental.” The major methodology for dealing with instabilities in ill-posed inverse problems, known as regularization, was developed by the legendary Russian mathematician Andreĭ Nikolaevich Tikhonov and his research groups at Moscow State University and the Soviet Academy of Sciences beginning in the 1960s. In 1984 I published the first English language monograph (The Theory of Tikhonov Regularization for Fredholm Equations of the First Kind, Pitman Advanced Publishing Program, London, 1984) devoted exclusively to regularization theory and containing a number of original results of my own, including the first precise elucidation of certain convergence properties of Tikhonov’s method for linear inverse problems. This book has been described in the journal literature as “very influential: it has … provided a firm basis for much subsequent work on regularization methods.” The book “Inverse and Ill-posed Problems” which I co-edited in the eighties with Heinz W. Engl (currently Rector of the University of Vienna) is considered an influential document in the field. Two of my widely cited books on inverse problems published in the nineties have helped shape and popularize the field of inverse and ill-posed problems. Inverse Problems in the Mathematical Sciences (Wiesbaden, 1993; Japanese translation, Tokyo, 1996) has been described as “a masterful work” in Zentralblatt für Mathematik and “unique in the mathematical literature” in SIAM Review. My book Inverse Problems (Washington, D.C., 1999; Japanese translation, Tokyo, 2002; Mandarin Chinese translation, Beijing, 2006) is termed “a remarkable contribution … in the field of inverse problems” and “a genuine treasure in the literature of inverse problems” in published reviews. My latest research monograph on stabilization theory for ill-posed problems (Stable Approximate Evaluation of Unbounded Operators) was published by Springer-Verlag in 2007. This monograph provides a general framework, from the perspective of inverse problems, of the basic procedure of evaluation of unbounded operators such as those that appear frequently in inverse problems in mathematical physics. My research on approximation methods for inverse and ill-posed problems has been presented in invited lectures on every continent of the globe except Antarctica. My work has been supported by the National Science Foundation, the Air Force Office of Scientific Research, the NATO Division of Scientific Affairs, and the Science and Engineering Research Council (U.K.) and I have held visiting research appointments in England, Germany, Switzerland, and Australia. The year 2010 brought a couple of notable honors in recognition of my contributions to the three “i”s. : The Journal of Integral Equations and Applications, an international research quarterly, dedicated its Summer and Fall issues in my honor. I was also one of ten mathematicians nation-wide elected Fellows of the American Association for the Advancement of Science (AAAS) in 2010. Founded in 1848, the AAAS is the world’s largest scientific society and includes 262 affiliated societies and academies serving 10 million individuals worldwide. Since 1874 the AAAS has bestowed, upon election by peers and approval by the AAAS Council, the designation of Fellow on select members whose “efforts on behalf of the advancement of science or its applications are scientifically or socially distinguished.” I was elected in recognition of my “distinguished contributions of the application of mathematics to science, particularly in the areas of inverse or ill-posed problems, approximation theory, and mathematical modeling.”