Appendix 1: Is it possible to have one high reliable scale with low ‘responsiveness’, and a low reliable scale with high ‘responsiveness’ measuring the same construct? Consider two scales A and B measuring the same construct before and after an effective intervention. Before intervention has expectation 1 and variance 12 . After the intervention has expectation 2 and variance 22 . The covariance between values before and after intervention is denoted as 12. Theta () is a latent construct and is quantified through scales A and B, assuming that both scales conform to the classical test theory. This means that observed values with scale A and B at baseline (Y1,A and Y1,B) may be seen as Y1,A= 1+e1,A and Y1,B= 1+e1,B, where e1,A and e1,B denote measurement-error each with expectation zero, and variances 12, A and 12,B . Reliability of scales A and B at baseline equals 12 /( 12 12, A ) , and 12 /( 12 12,B ) , and obviously, if B is more reliable than A, this means that measurement-error of A varies more than that of B: 12,B < 12, A . After intervention, classical test theory applies too: Y2,A= 2+e2,A and Y2,B= 2+e2,B, with error-variances 22, A and 22,B . Consider now the standardized response mean (SRM) as a measure of responsiveness. SRM for scale A is defined as y1, A y 2, A d SRM A , sd s12, A s22, A 2 s12, A where d is the average change, and sd the standard deviation of the changes, and where y1, A and y 2 , A are the observed means of scale A before and after intervention, and s12, A and s22, A the observed variances of scale A before and after intervention, and s12,A the covariance between the observed scale-scores. Obviously, expectation of the numerator of the SRMA equals 1-2, and the same is the case for the numerator of SRMB. Hence, any difference between SRMA and SRMB must be due to their denominators. The expected variances s12, A and s22, A are, off course, equal to s12, A = 12 + 12, A , and s22, A = 22 + 22, A . The expected covariance s12,A equals S12,A= 12 + cov(1,e1,A) + cov(2,e2,A) + cov(e1,A,e2,A). Since e1,A and e2,A are measurement-error terms (before and after intervention), they will have zero covariance, both with and with each other. Hence, the denominator of SRMA equals ( 12 + 22 -212)+ 12, A + 22, A , and using similar arguments the denominator of SRMB equals ( 12 + 22 -212)+ 12,B + 22,B . Inspection of the denominators of SRMA and SRMB shows that SRMA can only be larger than SRMB, when the measurement-error variance of scale A after intervention is smaller than that of scale B: 22, A << 22, B . Although this is not impossible, the occurrence is unlikely, especially when the reverse is the case before intervention. It is clear moreover that the difference in responsiveness is only a reflection of a difference in reliability between the two scales, since 22, A << 22, B implies that the reliability of scale B after intervention is lower than of scale A.