BIOSTATISTICS Phd PROGRAM COURSES
Code
Name
Biostatistics
Local Credit : 4
ECTS Credit: 6
BIS 801 Frequency distributions and descriptive statistics, table and graph methods,
sampling, theoretical distributions, hypothesis tests, simple linear correlation and
regression, statistical methods in biomedical experiments, critics of scientific
papers, statistical consultation.
Research Methods in Health Science
Local Credit : 4
ECTS Credit: 6
BIS 802
Scientific method, data, measurement methods and scale, casual relations, research
planning, types of research, research methods in epidemiology, sampling,
experimental design, survey methods, clinical experiments, blinding, possible
sources of error in researches, ethic rules in researches, preparing data for
analysis, report writing methods.
Sampling
Local Credit : 3
ECTS Credit: 6
BIS 803
Definition of sampling, sampling units and frame, simple random sampling,
stratified random sampling, cluster sampling, systematic sampling, probability
proportional to size sampling, multi-stage sampling, sample size.
Experimental Design
Local Credit : 3
ECTS Credit: 6
BIS 804 Principles of experimental designs, experimental error and replication, general block
designs, randomized incomplete designs, partial randomized designs, Latin-square
and high order Latin square designs, factorial designs, split-plot designs, general
rules in comparison of effects, fractional replications.
Statistical Methods Specific to Health Sciences
Local Credit : 3
ECTS Credit: 6
BIS 805
Vital, demographic and hospital statistics, measures of health levels, health
information systems, international classification of diseases.
BIS 806 Multivariate Analysis
Local Credit : 3
ECTS Credit: 6
Data matrix and descriptive statistics in multivariate analysis, standardization of
the rates and ratios, multivariate normal distribution, multivariate hypothesis tests,
principle component analysis, factor analysis, cluster analysis, discriminant
analysis, covariance analysis, canonic correlation.
Non-parametric Statistical Methods
Local Credit : 3
ECTS Credit: 6
BIS 807
Distribution free test statistics, Chi-square test, Kruskall Wallis test, Cohran Q test,
Friedman test, rank statistics, symmetry, independence and randomness tests, test
of goodness of fit, tests of relationship.
Data Analysis Using Statistical Package Software Programs
Local Credit : 3
ECTS Credit: 6
BIS 808 Data analysis witk package software programs, data entry, descriptive statistics,
examining properties of distribution, frequency tables, graphics drawing,
hypothesis tests, correlation and regression analysis.
Assessment of Hospital Patient Care
Local Credit : 3
ECTS Credit: 6
BIS 809 Definition of terms in hospital statistics, forms in hospital, hospital information
system, data for hospital statistics and data sources, assessment of hospital
patient care quality, policlinic statistics.
Multiple Regression Analysis
Local Credit : 3
ECTS Credit: 6
BIS 810 Multiple regression models, dependent and independent variables, correlation
matrix, proficiency in regression, multicollinearity, backward elimination method,
forward selection method, stepwise regression, principle components regression.
BIS 811 Rate, Proportions and Risk Analysis
Local Credit : 3
ECTS Credit: 6
Description of rate, ratio and proportion, comparison of ratios, standardization of
rates, descriptions of risk, risk measures.
Survival Analysis
Local Credit : 3
ECTS Credit: 6
BIS 812 The factors affecting survival, life tables, Kaplan-Meier method, Cox regression
analysis, logrank test, life table techniques to measurements of contraceptive
effectiveness, person-year method.
Epidemiology
Local Credit : 3
ECTS Credit: 6
Definition of epidemiology, historical development, application areas and
BIS 813 classification of research techniques, descriptive epidemiology, case-control
studies, cross-sectional study and population screening, cohort research,
intervention research, methodological research, the term “cause” in epidemiology,
error source in epidemiology, use of epidemiology in infectious disease and
epidemic, sampling methods, research planning and research report writing.
Logistic Regression
Local Credit : 3
ECTS Credit: 6
Definitions of logistic regression, logistic regression assumptions, multiple logistic
BIS 814 regression model, interpreting logistic regression coefficients, model building
strategies and methods, assessing model fitting, application of logistic regression
for different types of sampling methods, logistic regression in case-control
studies, polytomous logistic regression.
BIS 815 Advanced Analysis Using Statistical Package Software Programs
Local Credit : 3
ECTS Credit: 6
Data analysis using statistical package software programs and statistical
calculations (transforms,multiple correlation and regression analysis, principle
components method, covariance analysis, factor analysis, cluster analysis,
discriminant analysis, logistic regression).
Some Mathematical Models in Biology
Local Credit : 3
ECTS Credit: 6
BIS 816
Well Posed Problems in Tikhonov and Hadamard Sense, exercises, theoretical
and practical applications.
Health Information Systems
Local Credit : 3
ECTS Credit: 6
BIS 817
Historical development of information systems, science of management and
information, decision making and problem solving, system concept and
properties, information systems, management information systems, structuring
information systems, education strategy and staff training, health information
systems in Turkey.
Clinical Biostatistics
Local Credit : 3
ECTS Credit: 6
BIS 818
Planning and performing clinical researches, clinical experimental designs
(parallel, cross-over, serial and sequential designs), bioequivalence and phase
studies, error and bias sources, ethic rules, international norms, randomization
and blinding.
Time Series
Local Credit : 3
ECTS Credit: 6
BIS 819
Variations in time units, autocorrelation functions, static linear models, non static
linear models, moving averages, seasonal models, mixed models, multivariate
time series.
Advanced Mathematical Models in Biology
Local Credit : 3
ECTS Credit: 6
BIS 820 Dimensional analysis in mathematical biology, some dynamical systems in
biology, diffusion equations, biology of population, some models in epidemiology
and pharmacology, neurotransmission equations, Hodgkin & Huxley equations.
Harmonic Analysis I
Local Credit : 3
ECTS Credit: 6
BIS 821
Subgroup, class group, factorial group, projective limit, half metric, separation
axioms, compact and local compact Abel groups, integral in local compact
spaces, extend the linear functions, measurement composition space, integral in
product spaces, Haar integral.
Harmonic Analysis II
Local Credit : 3
BIS 822
ECTS Credit: 6
Convolution, convolution of functions, convolution of measurement,
representation theory, character group, the dual theory.
Health Knowledge
Local Credit : 3
ECTS Credit: 6
BIS 831
Cell and tissue, movement system, circulatory system and blood, respiratory
system, digestive system, cardiovascular system, urinary system, structure and
functions of nervous system, developments about health, care of various organs,
prevention of diseases.
Diseases Knowledge
Local Credit : 3
ECTS Credit: 6
BIS 832
Overall instructions about diseases, digestive system diseases, respiratory
system diseases, cardiovascular system and blood diseases, urinary system
diseases, endocrine system diseases, allergic diseases, joint diseases, surgical
diseases.
Medical Terminology
Local Credit : 3
ECTS Credit: 6
BIS 833
Overall instructions about terminology, historical development of medical
terminology, place of Greek and Latin languages in medicine terminology, basic
properties and Latin language and grammar rules, noun and noun clauses in
Latin language, prefix and suffixes in Latin language, terms about position and
direction, terms about human structure defining, eponym terms in medicine
terminology, effects of Greek language on medical terminology, usage of
terminology in clinical units.
Probability Theory
Local Credit : 3
BIS 841
ECTS Credit: 6
Description of probability and sample space, permutation and combination,
discrete random variables, continuous random variables, expected value,
variance and moments, discrete probability distributions, continuous probability
distributions, joint probability functions, conditional distributions.
Matrix Algebra
Local Credit : 3
ECTS Credit: 6
BIS 842
Definition of matrices, specific matrix types, basic arithmetical operations,
determinant, inverse and transpose, eigenvalue and eigenvectors, use of
matrices in statistical calculations.
Mathematical Statistics
Local Credit : 4
ECTS Credit: 6
BIS 843
Sum of random variables, stochastic inequality and limit laws, sample
distributions, order statistics, point estimation, best unbiased estimation,
efficiency, interval estimation.
Fundamental Biostatistics
Local Credit : 4
ECTS Credit: 6
Frequency distributions and descriptive statistics, table and graph methods,
sampling, theoretical distributions, hypothesis tests, simple linear correlation and
regression, statistical methods in biomedical experiments.
BIS 851
08.06.2011
Vildan SUMBULOGLU, MD,Phd, Prof.
Chairman of the Department of Biostatistics