RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES KARNATAKA, BANGALORE ANNEXURE-11 PROFORMA FOR REGISTRATION OF SUBJECTS FOR DISSERTATION 1. NAME OF THE CANDIDATE AND ADDRESS (IN BLOCK LETTERS) Dr. PALLAVI.G I M.D (Ayu) DEPARTMENT OF POST GRADUATE STUDIES IN AYURVEDA SIDDHANTA GOVERNMENT AYURVEDA MEDICAL COLLEGE MYSORE- 570021 D/O G.RAMA MOHAN #14/206 SAI RESIDENCY IST CROSS, DEVENDRA MUNIREDDY LAYOUT, CHIKKALASANDRA BANGALORE-560070 2. NAME OF THE INSTITUTION GOVERNMENT AYURVEDA MEDICAL COLLEGE MYSORE-570021 3. COURSE OF THE STUDY AND SUBJECT M.D (AYU) IN AYURVEDA SIDDHANTA 4. DATE OF ADMISSION OF COURSE 25-11-2009 5. TITLE OF THE TOPIC “A STUDY ON THE CONCEPT OF VARNYA VIS-A-VIS CLINICAL EVALUATION OF EFFICACY OF VARNYA GANA LEPA IN VYANGA.” 6. BRIEF RESUME OF THE INTENDED WORK 6.1) Need for the study The concept of beauty has an age old origin and it is as old as mankind and civilization. One of the ways of expression of this beauty is through the skin as beauty manifests through the appearance of the complexion of the skin. Ayurveda refers it as Varna. It is incorporated among the signs of health as it reflects the equilibrium of all the dhatus. It includes most of the parameters of healthy and radiant skin. Thus it acts as a barometer of individual’s health. In present society, complexion has become a great cause of concern to majority of individuals irrespective of their age group especially while presenting oneself in the society. This illustrates the social aspect of preference attitude of the society. Complexion which is the manifest form of beauty is enhanced by various means. This task of enhancement of complexion itself is termed as Varnya. Various treatment modalities such as Nasya ,Raktamokshana and Lepas have been mentioned by different Acharyas which are attributed to the Varnya Karma. Though Ayurveda has its own detail and deeper sense regarding the subject but all the literature concerned with Varna and Varnya is scattered throughout. So an attempt will be made in this study to systematically compile and review the relevant literature. Among the various Varna Vikaaras the prevalent and representative disorder considered in this study is Vyanga. Though it is painless but if affects the person psychologically. Any unhealthy state of physique or the psyche is reflected by the skin. There are not many statistics to prove the exact frequency of skin diseases in this country but the general impression is 10-20 percent of patients seek medical advise for skin diseases1. Hyper pigmentation is one among them which accounts for a great deal of anxiety and stress. Treatment modalities for hyper pigmentation are usually unsatisfactory as it shows exacerbation and remissions from time to time. It has various side effects such as contact dermatitis and complete depigmentation2. Therefore, there is need for evaluation of the problems of the society through the Ayurvedic perspectives and to find out some effective steps of management. Thus the study is designed with the hypothesis to evaluate the concept of and Varnya and to evaluate the effect of Charakokta Varnya Gana Lepa in the disease Vyanga. 6.2) Review of Literature The word Varna in general means colour of any substance. According to Sir Monier Williams:-The word Varna means the “outward appearance, exterior form, figure, shape, colour”, “colour of the face”, “good colour or complexion, lustre, beauty” 3. Kashyapa Samhita describes the equilibrium of all the dhatus as the root cause for vriddhi, bala, Varna, oja, agni, medha, ayu and sukha4. Sushruta Samhita explains the Varna Utpatti where in Tejo mahabhuta plays a major role in the formation of Varna5 and Four varieties of Prakrita Varna ie Goura, Krishna, Goura Shyama, Krishna Shyama have been explained.6 Charaka Samhita defines the word Varna as all those qualities which can be recognized by Chakşurīndriya 7 .Varna is not just colour but it includes all the parameters of healthy and radiant skin8. And mainly Four varieties of Prakrita Varna ie Krishna, Shyama, Shyaamaavadata and Avadata have been explained9. Ayurveda Shabda Kosha describes Varnya as Varnaaya hitam iti Varnyam-That which is hita for Varna is called Varnya10. Sharangadhara Samhita describes Varnya as Mukhavyangadi Varnakara ie that which normalises the mukha Vyanga11. Charaka Samhita includes Varnya Gana in 50 Mahakashaya in the Chapter Shadvirechana shatashriteeya Adhyaya. It includes 10drugs- Chandana, Tunga ,Padmaka, Ushira, Madhuka, Manjishta,Sariva, Payasya, Sita, Lata12. Charucharya describes Snana as the one which imparts Varna13. Various Ahara Dravyas have been attributed to Varnya Karma such as Kurma mamsa in Mamsa Varga14 and Pakva Rasa in Madhya Varga15. Sushruta Samhita considers Vyanga among the Kshudra Rogas. Vyanga is one of the diseases mainly characterized by Neeruja, tanu, shyaava, mandala16. Astanga Hrudaya also considers Vyanga as one among the Kshudra Rogas. Four varieties of Vyanga ie Vataja, Pittaja, Kaphaja, Raktaja have been described17. Charaka Samhita includes Vyanga among Rakta doshaja vikara in Vividhaashitapeetiya adhyaaya18 and Trishotheeya adhyaaya19. Sushruta Samhita includes Vyanga as one among the Rakta Dhatu Vikara in Vyadhisamuddesheeya adhyaaya20. Astanga Hrudaya describes Nasya with Kumkumaadi dravyas for Vyanga21. Sushruta samhita describes Siramokshana for Vyanga22. Sharangadhara Samhita describes Varnya lepa for Vyanga. Its dimension is said to be as half angula23..Duration upto which lepa has to be retained is also been described24. In order to prevent Vyanga Pidaka Mukhalepa has been included as a part of Dinacharya25. 6.3) Previous Research works 1. Prakash -Effect of Nasya karma in Vyanga Department of Kaya chikitsa 1994 Government Ayurveda Medical College Mysore. 2. Goyal R.K -Charakokta varnya mahakashaya ki vividha kalpanaae evam varnya prabhaavaatmaka adhyayana, Department of Rasashastra 1998 Udaipur. 3. Angadi Savita.S -Evaluation of efficacy of mukha lepa in vyanga vis a vis arjuna twak lepa and Pancha nimba churna internally. Department of Dravya Guna 2001 Bangalore 4. Shilpa Sawalia -Process and principles of Varnotpatti and Assessment of the Varna Prasadana in twak vaivarnya, Department of Basic Principles 2008 Jamnagar. 6.4) Objectives of the Study 1. To systematically compile and review the literature on the concept of Varna, Varnya and Vyanga . 2. To clinically evaluate the efficacy of Charakokta Varnya Gana Lepa in Vyanga. 7. MATERIALS AND METHODS 7.1) Source of data a. Literary sources- All the available data on Varna Varnya and Vyanga collected from Ayurvedic Classics, Vedas, Upanishads, Epics, Western medical texts and other allied texts. Other sources will include various journals and research works, retrospective studies carried out at different universities, and information from internet will be included to carry out the present work. b. Sample- A minimum of 30 individuals coming under inclusion criteria will be selected for the study. 7.2) Method of Collection of Data 1 Patients who are fulfilling the diagnostic criteria with respect to age, irrespective of sex, cast, religion and socio-economic status will be selected. 2 A minimum of 30 individuals coming under inclusion criteria approaching the IPD and OPD of Government Ayurveda Medical College and hospital, Mysore and special camps conducted will be selected for the study. 3. The study design will be Clinical Observational with a pre and post test assessment. 4. Patients will be assigned to a single group. 5. The results of the present study will be analyzed statistically using Descriptive Statistics, Frequencies and Percentages, Cross tabulation (Contingency Table Analysis), Chi-Square test using SPSS for windows (version 18.0 ). Inclusion Criteria 1. Patients with clinical signs of the disease Vyanga as per ayurvedic classics will be included. 2. Patients between age group of 16-60 years will be selected for the study. 3 Patients irrespective of sex, religion, occupation, and chronicity will be selected for the study. Exclusion criteria 1 Hyperpigmentation caused due to any systematic disease like Addisons disease, Cushings syndrome and SLE. 2 Hyperpigmentation since birth like Neavus 3. Hyperpigmentation caused by tumor like malignant melanoma. Diagnostic Criteria Objective parameters 1. Shyaava 2. Mandala 3. Tanu Assessment criteria The improvement provided by the therapy will be assessed on the basis of following parameters. 1. Texture (Dry /Oily) 2. Skin Luster (Depends on the oil content of the skin) 3. Skin color 7.3 DOES THE STUDY REQUIRE ANY INVESTIGATIONS OR INTERVENTIONS TO BE CONDUCTED ON THE PATIENTS OR OTHER HUMANS OR ANIMALS? IF SO PLEASE DESCRIBE BRIEFLY YES No specific investigations are done for the study. The study requires interventions to be conducted on patients. INTERVENTION 1. Initially the patient will be advised to clean the face with water. 2. Content of the Lepa- Consists of 10 drugs Chandana ,Tunga(Punnaga), Padmaka, Ushira Madhuka, Manjishta, Sariva, Payasya, Sita (Shweta Durva) Lata (Shyama Durva).Sukshma churna of all these drugs in equal quantity are mixed with water to form thich paste and is given for application on the affected areas. 3. Thickness of the lepa- 0.5-0.8mm 4. Dose- Quantity sufficient 5. Duration of each application-Retained until it gets dried and once it dries the patient is asked to wash the face with water. 6. Duration - For 15 days once daily in the morning. 7.4) HAS THE ETHICAL CLEARANCE BEEN OBTAINED FROM YOUR INSTITUTION IN CASE OF 7.3? YES 7. LIST OF REFERENCES 1. P.N.Behl,A.Aggarwal, Govind Srivastav, Practice of Dermatology. 9th Edition New Delhi CBS Publishers and Distributors 2002 PP-1 2. P.N.Behl,A.Aggarwal, Govind Srivastav, Practice of Dermatology. 9th Edition New Delhi CBS Publishers and Distributors 2002 PP-300 3. M.Monier- Williams-A Sanskrit English Dictionary- Reprint-2005 Delhi Motilal Banarasidars Publishers PP -924 4. Pandit Hemarajasharma Sharma Kashyapa Samhita Varanasi Chaukambha Sanskrit Samsthan Reprint 2009 PP-41 5. Acharya Yadavji Trikamji Sushruta Samhita 8th Edition Varanasi, Chaukhamba Orientalia, 2005 PP-348 6. Acharya Yadavji Trikamji Sushruta Samhita 8th Edition Varanasi Chaukhamba Orientalia, 2005 PP-348 7. Acharya Yadavji Trikamji Charaka Samhita 5th Edition Varanasi Chaukhamba Sanskrit Samsthan 2001 PP-353 8. Acharya Yadavji Trikamji Charaka Samhita 5th Edition Varanasi Chaukhamba Sanskrit Samsthan 2001 PP-353 9. Acharya Yadavji Trikamji Charaka Samhita 5th EditionVaranasi Chaukhamba Sanskrit Samsthan 2001 PP-355 10. Venimadhav Shastri Joshi, Narayan Hari Joshi Ayurvedeeya Shabda Kosha Prathama Khanda Nirnay Sagar Press PP- 725 11. Parashuram Shastri Vidyasagar, Sharangadhara Samhita 6th Edition Varanasi Chaukhamba Orientalia 2005 PP-356 12. Acharya Yadavji.Trikamji Charaka Samhita 5th Edition Varanasi Chaukhamba Sanskrit Samsthan 2001 PP-32 13. Bhojaraja Charucharya Central Council of Research in Ayurveda and Siddha Translated in 2000 PP-19 14. Acharya Yadavji Trikamji Charaka Samhita 5th EditionVaranasi Chaukhamba Sanskrit Samsthan 2001 PP-158 15. Acharya Yadavji Trikamji Charaka Samhita 5th EditionVaranasi Chaukhamba Sanskrit Samsthan 2001 PP-161 16. Acharya Yadavji.Trikamji Sushruta Samhita 8th Edition Varanasi Chaukhamba Orientalia, 2005 PP-324 17. Pandit Hari Sadashiva Sastri Paradakara- Astanga Hrudaya 9th Edition Varanasi Chaukhamba Surabharati Prakashan 2005 PP-889 18. Acharya Yadavji Trikamji Charaka Samhita 5th Edition Varanasi Chaukhamba Sanskrit Samsthan 2001 PP-179 19. Acharya Yadavji.Trikamji Charaka Samhita 5th Edition Varanasi Chaukhamba Sanskrit Samsthan 2001 PP-107 20. Acharya Yadavji Trikamji Sushruta Samhita 8th Edition Varanasi Chaukhamba Orientalia, 2005 PP-116 21. Pandit Hari Sadashiva Sastri Paradakara- Astanga Hrudaya 9th Edition Varanasi Chaukhamba Surabharati Prakashan 2005 PP-892 22. Acharya Yadavji Trikamji Sushruta Samhita 8th Edition Varanasi Chaukhamba Orientalia, 2005 PP-480