Administrative Office St. Joseph's Hospital Site, L301-10 50 Charlton Avenue East HAMILTON, Ontario, CANADA L8N 4A6 PHONE: (905) 521-6141 FAX: (905) 521-6142 http://www.fhs.mcmaster.ca/hrlmp/ Issue No. 69 QUARTERLY NEWSLETTER June 2003 Perioperative Blood Conservation Program Many examples of Perioperative Blood Conservation programs exist in Canada. Each program may differ in terms of composition, but all are similar in the ability to provide benefits to key healthcare stakeholders. Perioperative Conservation programs can be seen as threads that tie different stakeholder interests together, with the common goal of better patient care. The move towards alternatives to allogeneic blood transfusion has in part been driven by greater public awareness of inherent risks of donated blood and public fear, still prevalent despite considerable measures to increase safety of the blood supply system. Hamilton Health Sciences (HHS) is one of 23 sites participating in a Government of Ontario sponsored program, ONTraC (Ontario Nurse Transfusion Co-ordinators), designed by Dr. John Freedman, Chief Hematologist for St. Michael’s Hospital, Toronto. It is managed at each site by a Blood Transfusion Co-ordinator who plays an integral role in the implementation of hospital blood conservation strategies, evaluation of practices and problem solving. The program uses the principles of evidence-based practice and patient centred care. The program was established at HHS 18 months ago and is designed to restore confidence to patients and physicians concerned with transfusion transmitted diseases (e.g. HIV, Hepatitis, West Nile Virus, etc.), and has three goals: Through education, reduce the number of allogeneic transfusions; Make information available that will inform patients about non-blood products; Improve general awareness regarding blood/blood products. Benefits for both Patient and Health Care Professionals The program offers numerous benefits to patients who require a blood transfusion and the health care professionals who look after them. The program expects to benefit patients through: Receiving appropriate information regarding blood, blood products and alternatives. Having sufficient lead-time to make informed and viable decisions (with health care professionals). Anemia is managed without unnecessary exposure to donated blood. Recovery time from surgery, treatment, or illness is reduced, leading to better outcomes. Better quality of life, including resumption of daily activities, increased “vigor” for rehabilitation. Lack of exposure to risks of allogeneic blood, including, iatrogenic diseases, hemolytic reactions and decreased risk of immunosuppression. By collecting evidence it is hoped that health care professionals will benefit through: Performing continual prospective tracking of utilization of blood, blood products and alternatives for the purpose of making knowledgeable recommendations for use. Establishing policies and procedures aimed at minimizing exposure to allogeneic blood, preventing postponements and cancellations of surgeries at times of blood shortages. Assessing new therapies and alternatives as they become available and recommend use. Use of evidence-based principles and cost/benefit analysis where appropriate. Education forum for healthcare professionals on blood, blood products and alternatives. Establish informed consent as part of standard perioperative protocol. The Hospital should see benefits that include less unnecessary use of blood resources with blood saved for emergencies and other uses, fewer co-morbidities and complications resulting in less of a need for follow-up and reduced average length of hospital stay. What’s Happened at Hamilton Health Sciences? Following a review by the transfusion co-ordinator, new flow sheets and patient education materials have been developed for the use of blood and blood products that better represent the term “informed consent”. Two pamphlets about autologous donation and decreasing a patient’s need for a blood transfusion have been developed to help patients education and to provide answers to some of their more common questions. In order to provide a better service to patients a process is currently being designed that will take the program into the community. Retrospective Audit The biggest challenge/success was the results of the retrospective audit carried out in the fall of 2001. A prospective audit was undertaken in March, 2003, confirming the findings of the original audit and was presented at the recent Canadian Society of Transfusion Medicine Conference in Halifax. In the audit six surgeons who performed primary coronary artery bypass surgery were followed. The results found are below. Blood Utilization: Number of patients Retrospective Audit Prospective Audit October 2001 March 2003 70 60 72.5% 63% 7.7% 7.8% Average Hb on admission 137.2 g/L 137 g/L Average Hb on discharge 99.7 g/L 99.5 g/L Average transfusion trigger 80 g/L 80 g/L Utilization by individual surgeon utilization Autologous utilization 80 g/L 80 g/L <8% <8% Percentage patients transfused Autologous utilization Conclusion In this CABG cohort there appears to have been a transfusion trigger of 80 g/L. Very few RBC transfusions occurred in the absence of a low Hgb (<80 g/L) or hypotension. Autologous use was minimal (approx. <8%) and its use appeared not to be based on clinical grounds (low Hgb and/or low blood pressure). Variance amongst surgeons was minimal. Petra Cooke, RN BScN, Transfusion Coordinator, Hamilton General Hospital Site Hamilton Regional Laboratory Medicine