Eighth Annual David Fromm Research and Wayne State Surgical Alumni Day Thursday, October 24, 2013 Margherio Family Conference Center, Wayne State University School of Medicine Conference Chair: Scott A. Gruber, M.D., Ph.D., MBA 7:30 – 8:00 AM Continental Breakfast 7:45 – 8:00 AM Welcome and Introductions: Scott A. Gruber, M.D., Chief of Staff, John D. Dingell VA Medical Center Associate Dean for Veterans Affairs & Professor of Surgery Donald W. Weaver, M.D., Penberthy Professor and Chairman, Department of Surgery All presentations will be 15 minutes in length with 5 minutes for Q & A 8:00 – 10:00 AM - First Session: Basic Research Moderator: Donald W. Weaver, M.D. (1) David H. Gorski, M.D., Ph.D., Medical Director, Alexander J. Walt Comprehensive Breast Center, Barbara Ann Karmanos Cancer Institute and Associate Professor of Surgery: “Riluzole as a Treatment for Breast Cancer” (2) M. Salik Jahania, M.D., Associate Professor of Surgery: “Use of intra-arterial supersaturated aqueous oxygen in a swine model of acute normovolemic anemia”. Coauthors: L Muthukumar, P Percvsky, JR Spears. (3) M. Salik Jahania, M.D., Associate Professor of Surgery: “Effects of ischemiareperfusion on authophagy in the human heart”. Co-author: RM Mentzer, Jr. (4) Oksana Gruzdyn, B.S., Graduate Student in Laboratory of Scott A. Gruber, Donald W. Weaver, and Ramesh Babu Batchu, Ph.D., Assistant Professor of Surgery and Associate Professor of Microbiology: “Enhancer of zeste homolog 2 silencing downmodulates mutant p53 with increased chemosensitivity in epithelial ovarian cancer” (5) Shu T. Kung, B.S., Medical Student in Laboratory of Scott A. Gruber, Donald W. Weaver, and Ramesh Babu Batchu, Ph.D., Assistant Professor of Surgery and Associate Professor of Microbiology: “Novel AAV-DJ capsid tyrosine mutants with enhanced transgene expression” (6) Oksana Gruzdyn, B.S., Graduate Student in Laboratory of Scott A. Gruber, Donald W. Weaver, and Ramesh Babu Batchu, Ph.D., Assistant Professor of Surgery and Associate Professor of Microbiology: “MAGE-A3 with cell-penetrating domain as an efficient therapeutic cancer vaccine” 10:00 – 10:20 AM Coffee Break 10:20 AM – 12:00 PM Second Session: Translational/Clinical Research and Surgical Education Moderator: Scott A. Gruber, M.D., Ph.D., MBA (7) Michelle Veenstra and Brady King, Researchers in Laboratory of Michael Klein, M.D., Professor of Surgery, Al Philippart Chair, Pediatric Surgical Research: “Raman Spectroscopy in the Diagnosis of Hirschsprung's Disease” and “Automated Horizon Stabilization in Laparoscopic and Robotic Surgery” (8) Rachel Kast, Assistant Professor-Research, Smart Sensors and Integrated Microsystems group of Gregory Auner Ph.D.: “Characterization of Adipose Tissue from Bariatric Surgery Patients as a Potential Disease Risk Indicator Using Raman Spectroscopy”. Co-authors: M Wood, B Seyoum, S Tucker, K Honn, S Yurgelevic, G Auner. (9) Arlene Rozzelle, M.D., Associate Professor of Surgery, Division of Plastic Surgery: "Interesting vascular anomalies cases". Co-author: K Pappas (10) Asra Hashmi, M.D., Resident in Laboratory of Frank A. Baciewicz, M.D., Professor of Surgery, Division of Cardiothoracic Surgery: “Does Preoperative Pulmonary Rehabilitation Affect Outcomes in Low FEV1 Patients Undergoing Lung Cancer Resection” (11) David Bouwman, M.D., Former Professor of Surgery and Walt Chair in Surgical Education: “Simulation Now for Surgical Skill Acquisition” 12:00– 1:00 PM Lunch Brief address by: David Fromm, M.D., formerly Penberthy Professor and Chairman, Department. of Surgery Presentation of Wayne State Surgical Alumnus of the Year Award to Hubert Huebl, M.D. 1:00 – 2:00 PM - 4th Annual Scott Woods Lecture: Herbert Chen, M.D., FACS Chairman, General Surgery, Professor of Surgery & Vice-Chair for Research Layton F. Rikkers, M.D. Chair in Surgical Leadership University of Wisconsin School of Medicine and Public Health "Advances in Parathyroid Surgery and Intraoperative PTH Monitoring” ______________________________________________ “The Wayne State University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Wayne State University School of Medicine designates this live activity for a maximum of 5.00 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.”