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MORPHOLOGICAL PREDICTORS OF ADVERSE OUTCOME Publication Predictor Early Late Overall events events events Event definition (<2wks) Kunishige Patent FL Significant 2006 [70] Sakakura Dissection-related event (p=0.018) Patent FL 2007 [77] Non- In-hospital events: death, Significant need for (p=0.14) emergent surgery for (impending) rupture, organ malperfusion Kitada 2008 [12] Patent FL Non- Dissection-related aortic Significant events: (p=0.537) deaths from aortic rupture, perioperative death, death from organ ischemia, aortic (impending) rupture, recurrence of dissection, aortic expansion ≥60mm, expansion of dissected aorta ≥ 10mm/yr, visceral/limb ischemia Publication Predictor Early Late Overall events events events Event definition (<2wks) Takahashi Patent FL Non- 2008 [71] Significant (p=0.22) Dissection-related event: need for aortic surgery, aortic rupture, dissection-related death, mean aortic enlargement >5mm in diameter/year Suyeoshi Patent FL Non- 2009 [72] Increased diameter Significant (p=0.6486) Stanley 2011 Patent FL [78] Significant Smaller expansion of true (p=0.02) lumen volume after stentgraft Mani 2012 Patent FL [63 ] significant Significant Smaller Remodeling (>0.5 (p=0.01) cm reduction in maximum descending Ø) Tsai 2007 [73] Partial FL Significant Thrombosed (p=0.002) Death Publication Predictor Early Late Overall events events events Event definition (<2wks) Song 2007 [74] FL Ø ≥22mm at Significant upper (p<0.005) Late aneurysm change descending Winnerkwist Max aorta Significant 2006 Ø≥ 40mm (p=0.02) Aortic events: Dissection related [7] death, rupture, new Type A aortic dissection, aneurysm formation Hata 2007 Max aorta Significant [8] Ø≥ 40mm (p=0.0003) Kitada 2008 Max aorta Non- [12] Ø≥ 40mm Significant Elective Surgery See Kitada (p=0.068) Takahashi Max aorta Significant 2008 [71] Ø≥ 40mm (p=0.032) Kunishige Max aorta Significant 2006 Ø≥ 45mm (p=0.004) See Takahashi Dissection-related event [70] Sakakura Max aorta Significant See Sakakura Publication Predictor Early Late Overall events events events Event definition (<2wks) 2007 Ø≥ 60mm (p=0.03) [77] Song 2007 Large aorta Ø at [74] upper Significant See Song (p<0.05) descending thoracic aorta Chang 2008 Max aortic Ø [75] Non- In-hospital complications: Significant Compromised renal artery, (p=UNK) limb/mesenteric ischemia, (impending) rupture/progression of dissection Kitai 2010 [76] Max aortic Ø Significant Aorta-related events: (per 10 mm (p<0.001) rupture, increment) lower limb/visceral ischemia, aortic enlargement ≥ 60 mm Andache Dissection Non 2012 extended to significant Aortic volume (p=0.81) and diameter p=0.18) Publication Predictor Early Late Overall events events events Event definition (<2wks) [62] Chang 2008 [75] Winnerkvist 2006 infrarenal aorta increase at 1 year Max FL Area Significant ≥ 922 mm2 (p=0.02) See Chang Development Significant ULPs (p=0.005) See Winnerkvist [7] Kunishige 2006 Development Non- ULPs significant [70] Kitai 2010 See Kunishige (p=0.387) Development Significant ULPs (p=0.001) Miyahara Development of Significant rupture and expansion or 2011 [18] ULPs/ Patent FL (p=0.009) malperfusion with need for [76] See Kitai open surgery or thoracic endovascular repair (p=0.009) Sueyoshi Location of Significant 2009 entry site in arch (p=0.0431) See Sueyoshi [72] Mani 2012 Aortic significant Significant Mid term survival Publication Predictor Early Late Overall events events events Event definition (<2wks) [63 ] remodeling (>0.5mm reduction Ø descending) FL: False lumen; ULP: Ulcer like projections (p=0.005) (p=0.005)