CURRICULUM VITAE
Richard Harrison Rothman, M.D., Ph.D.
Education:
University of Pennsylvania
College of Arts and Sciences
B.A. (Major, History) 1958
University of Pennsylvania
School of Medicine
M.D. 1962
Jefferson Medical College
Department of Anatomy
Ph.D. 1965
Postgraduate Training and Fellowship Appointments:
Internship – Philadelphia General Hospital, 1963
Residency – Jefferson Medical College Hospital, Orthopaedic Surgery, 1963-68
Military Service:
Captain, M.D., USAR, 348th General Hospital
Faculty Appointments:
James Edwards Professor and Chairman of the Department of Orthopaedic Surgery
Jefferson Medical College of Thomas Jefferson University, 1986 – 2006.
Director of Orthopaedic Surgery
Pennsylvania Hospital, 1970
Professor of Orthopaedic Surgery
University of Pennsylvania School of Medicine, 1979
Administrative Appointments:
Director, Orthopaedic Research Laboratory, Jefferson Medical College 1969-70
Vice President, Philadelphia Orthopaedic Society, 1973
President, Cervical Spine Research Society, 1977
President, Jefferson Orthopaedic Society, 1976
Executive Committee, International Society for Study of the Lumbar Spine, 1974-1976
1
American Academy of Orthopaedic Surgeons:
Regional Admissions Committee
Committee on the Spine
Board of Directors
Committee on Examinations
Committee on Outcome Studies
Examiner, American Board of Orthopaedic Surgery
Board Member, Annenberg Institute
President, Professional Staff, Pennsylvania Hospital, 1986
Overseer, College of Arts and Sciences, University of Pennsylvania
Associate Trustee, University of Pennsylvania
Trustee, Brandywine Museum
Board Member, First Health, Inc.
Board Member, Orthopaedic Research and Education Foundation
Trustee, Pennsylvania Hospital
Board Chairman, Specialty Care Network
Board Chairman, STRIVE
President, American Association of Hip and Knee Surgeons
Specialty Certification:
Diplomat, American Board of Orthopaedic Surgery, 1970
Fellow American Academy of Orthopaedic Surgeons
Licensure:
Pennsylvania, New Jersey, and Colorado
Awards, Honors and Membership in Honorary Societies:
Post-Doctoral Fellow, National Institutes of Health
Andry Award, Association of Bone and Joint Surgeons for research in orthopaedic
surgery
2
Creskoff Award, University of Pennsylvania for research in hematology, 1958
C.W. LaBelle Award for Research, 1963
Member:
Phi Beta Kappa
Alpha Omega Alpha
Siga XI
Award for best scientific paper, Association of Bone and Joint Surgeons, 1983
Volvo Award for scientific research in the area of the spine, 1984
Distinguished Alumni Award, Thomas Jefferson University, 1988
Sir John Charnley Award, 2000
Insall Award (Knee Society) – Why are Total Knee Arthroplasties Failing Today?, 2002
Named in:
Best Doctors in USA, 1979
Best Doctors in America, 1993
Best Doctors in America, American Health, 1996
Easter Seals Award, 1997
Frank Stinchfield Award – Hip Society, 2004.
Distinguished Basic Science Paper Award (Musculoskeletal Infection Society) 2004.
Vernon Nickel Aware (PM&R), 2004.
Corporate Boards
Cross Current
Medical Society Memberships:
Philadelphia County Medical Society
Pennsylvania Medical Society
American Medical Association
American Association for Advancement of Science
American Association of University Professors
American College of Surgeons
3
Orthopaedic Research Society
Eastern Orthopaedic Association
Canadian Orthopaedic Association
Cervical Spine Research Society, President, 1977
American Academy of Orthopaedic Surgeons:
Regional Admissions Committee
Committee on the Spine
Board of Directors
Committee on Examinations
International Society for Study of the Lumbar Spine, Executive Committee 1974-1976
Medical Club of Philadelphia
Philadelphia Regional Committee on Trauma (ACS)
New York Academy of Sciences
Association of Bone and Joint Surgeons
American Orthopaedic Association
Fellow, Philadelphia College of Physicians
Hip Society
American Association of Hip and Knee Surgeons
Editorial Positions:
Clinical Orthopaedics and Related Research, Editor
The Spine, Editor
Seminars in Arthroplasty, Editor-in-Chief
Operative Techniques in Orthopaedics, Editor
The Journal of Arthroplasty, Editor-in-Chief
Visiting Professorships:
Gorgas Hospital, 1974
4
Harvard Medical School, 1975
William Beaumont Army Medical Center, 1975
University of Miami, 1975
Thomas Jefferson University, 1976
Harvard Medical School, 1976
Baylor University, 1976
St. Luke’s Hospital, 1976
University of Southern California, 1976
Hospital for Joint Disease, 1976
Mayo Clinic, 1977
University of Washington, 1977
Henry Ford Hospital, 1978
University of Chicago, 1980
University of Georgia, 1981
Cleveland Clinic, 1982
Harvard Medical School, 1982
UCLA, 1982
Harvard Medical School, 1984
University of California, San Diego, 1984
University of Miami, 1985
University of Texas, 1986
Hospital for Joint Diseases, New York, 1986
New England Baptist Hospital, Boston, 1987
Albert Einstein College of Medicine, 1991
Louisiana State University, 1991
Johns Hopkins, 1993
University of Virginia, 1993
New England Baptist Hospital, 2001
Harvard Medical School, 2001
University of Pittsburgh Medical Center, 2002
University of Texas, 2005
University of Chicago, 2005
Lennox Hill Hospital, 2005
Bibliography:
Original Papers:
1.
Rothman, Richard H. and Machella, T.: The Effect of Glycopyrrolate on Gastric
Secretion. The Journal of New Drugs 3:106-109, March 1963.
2.
Rothman, Richard H.: The Anatomy of the Human Rotator Cuff. The Anatomical
Record 148:329, February 1964.
5
3.
Rothman, Richard H., Depalma, A.F., and Parke, W.W.: Congenital Abnormality of the
Radio-Ulnar Syndesmosis. Clin Orthop 36:156-158, December 1964.
4.
Rothman, Richard H.: The Effect of Aging on Tendon Capillary Bed. The Anatomical
Record 151:3, 1965.
5.
Rothman, Richard H. and Parke, W.W.: The Vascular Anatomy of the Rotator Cuff, Clin
Orthop 41:176-186. July, 1965.
6.
Rothman, Richard H. and Slogoff, S: The Effect of Immobilization on the Vascular Bed
of Tendon. Surgery, G. & O. 124:1064-1067, May 1967.
7.
Rothman, Richard H.: Electrical and Mechanical Principals in Bone Bio-dynamics.
Chapter in Engineering in the Practice of Medicine, edited by Segal and Kilpatrick,
Williams and Wilkins, Baltimore, 1967.
8.
Rothman, Richard H. and Rubin M.: Tendon Calcifications and Vascularity. Surgery, G.
& O. 125-577-580, 1967.
9.
Rothman, Richard H. and DePalma, Anthony F.: The Nature of Pseudarthrosis, Clin
Orthop 59:113-118, 1968.
10.
Rothman, Richard H. and Judson, James: The Vascular Response of Connective Tissue
to Immobilization. The Anatomical Record 160.2, p. 418, 1968.
11.
Rothman, Richard H. and DePalma, Anthony F.: Surgery of the Lumbar Spine. Clin
Orthop 63:162-170, 1969.
12.
Rothman, Richard H.: Effect of Anemia on Fracture Healing. Surgical Forum Vol. 19,
1968.
13.
Rothman, Richard H. and DePalma, Anthony F.: Osteotomy of the Hip. Clin Orthop
73:109-115, 1970.
14.
Rothman, Richard H.: The Clinical Syndrome of Lumbar Disc Disease. Orthop Clin N
Am 2:463-475, 1971.
15.
Rothman, Richard H.: The Conservative Treatment of Cervical Disc Disease. Orthop
Clin N Am 2:435-441, 1971.
16.
Rothman, Richard H.: The Effect of Hypoferremia on Fracture Healing. Clin Orthop 76,
1971.
17.
Rothman, Richard H. and Campbell, R.: Total Hip Replacement. Am J Roent 113:4
634-41. December, 1971.
6
18.
Rothman, Richard H. et al: Anterior Interbody Fusion for Severe Cervical Disc
Degeneration. Surg. G. & O. 134:755-758, 1972.
19.
Rothman, Richard H. et al: Cervical Disc Degeneration, Natural History. Acta Orthop
Scand Vol. 43, 392-396, 1972.
20.
Rothman, Richard H.: Indications for Lumbar Fusion. Clinical Neurosurgery. Chapter
17, 215-219, 1973.
21.
Rothman, Richard H.: The Pathophysiology of Disc Degeneration. Clinical
Neurosurgery . Chapter 12, 174-182, 1973.
22.
Rothman, Richard H. et al: Infection of the Cervical Spine – Chapter in the Cervical
Spine – edited by Robert Bailey, M.D., Lea and Febiger, 1974.
23.
Rothman, Richard H. et al: Current Concepts in Osteomyelitis – Chapter in Diagnosis of
Treatable Disease edited by Orville Horwitz, Lea and Febiger, 1973.
24.
Rothman, Richard H. et al: The Aging Spine. The Anatomical Record 175:430-431,
1973.
25.
Rothman, Richard H.: New Developments in Lumbar Disc Surgery. Orthop Review 4,
23-30, 1975.
26.
Rothman, Richard H. et al: Myelographic Patterns in Lumbar Disc Degeneration, Clin
Orthop 99:18-29, 1974.
27.
Rothman, Richard H.: The Acute Cervical Disc. Clin Orthop 109:59-68, 1975.
28.
Rothman, Richard H., Booth, R.: Failures of Spinal Fusion. Orthop Clin N Am 6:299304, 1975.
29.
Rothman, Richard H. et al: Anatomic Considerations in the Gleno-Humeral Joint.
Orthop Clin N Am 6:341-352, 1975.
30.
Rothman, Richard H., Marvel, James P. Jr., Heppenstal, R. Bruce: Recurrent Anterior
Dislocation of the Shoulder. Orthop Clin N Am Vol. 6, No. 2:415-422, 1975.
31.
Rothman, Richard H. et al: The Painful Charnley Total Hip. Am J Radiology 121:61-68,
1974.
32.
Rothman, Richard H. et al: The Facet Joint: Another Look. Bulletin of the N.Y.
Academy of Science 51:1294-1311, 1975.
33.
Rothman, Richard H. and Booth, R.: Cervical Angina. The Spine 1:28-32, 1976.
7
34.
Rothman, Richard H. et al: Intra-dural Neurofibromas Simulating Lumbar Disc Disease.
J. Boint Surg 58-A:1040, 1976.
35.
Rothman, Richard H.: Salvage Spine Surgery. Clin Orthop 119:281, 1976.
36.
Rothman, Richard H. and Parke, W.W.: Dorsal Sacro-Dural Ligaments in the Human
Fetus. Anal Record 187:676-677, 1977.
37.
Rothman, Richard H. et al: Diagnosis and Treatment of Low Back Pain. Dallas Medical
Journal 1977.
38.
Rothman, Richard H. et al: Salvage Spine Surgery. Orthop Transactions 1:41, 1977
39.
Rothman, Richard H.: Lesions de la Columna Cervical. Third Symposium International
de Traumatologia 3:110-119, 1977
40.
Rothman, Richard H.: La Fisiopatologia de la Degenervacion Discal. Third
Symposium International de Traumatologia 3:312-323, 1977.
41.
Rothman, Richard H.: Tecnica y Resultados de la Laminetecvia Lumbar. 3:342-350,
1977.
42.
Rothman, Richard H. and Parke, W.W.: Comparative Arterial Vascularization of Cervical
Spinal Nerve Roots. Orthop Transactions 2:30, 1978.
43.
Rothman, Richard H. et al: Pathogenesis of Signs and Symptoms of Cervical Disc
Degeneration. AAOS Instructional Course Lectures XXVII, Chapter 14, 203-215, 1978.
44.
Rothman, Richard H. et al: Atlanto-Occipital Hypermobility. Orthop Clin N Am 9:969972 1978.
45.
Rothman, Richard H. et al: New Concepts in the Diagnosis and Treatment of Infections
of the Cervical Spine. Orthop Clin N Am 9:1039-1051, 1978.
46.
Rothman, Richard H. and Parke, W. W.: The Venous Relations of the Median AtlantoAxial Articulation. Anatomic Record.
47.
Rothman, Richard H. and Holmes, Hamilton E.: The Pennsylvania Plan: An Algorithm
for the Management of Lumbar Degenerative Disc Disease. Advances in Pain Research
and Therapy, Vol. 3 edited by John J. Bonica, Raven Press, New York, 1979, p. 699-711.
48.
Rothman, Richard H. and Wiesel, Sam W.: Occipitoatlantal Hypermobility, Spine 4:178191, 1979.
49.
Rothman, Richard H.: Microsurgery and the Technique of Lumbar Laminectomy. AAOS
Symposium on Microsurgery. Ch. 12, 153-169, 1979.
8
50.
Rothman, Richard H. and Holmes, Hamilton E.: The Pennsylvania Plan: An Algorithm
for the Management of Lumbar Degenerative Disc Disease. AAOS Instructional Course
Lectures Volume XXVIII 1979, pp. 193-200.
51.
Rothman, Richard H. and Holmes, Hamilton E.: Technique of Lumbar Laminectomy.
AAOS Instructional Course Lectures Volume XXVIII 1979, pp. 200-207.
52.
Rothman, Richard H. et al: Results of Surgical Intervention in the Symptomatic MultiplyOperated Back Patient. J Bone Joint Surg 61 -A, October 1979, pp. 1077-1082.
53.
Rothman, Richard H. and Marvel, James P.: Orthopedic Surgery Chapter in Outpatient
Surgery, edited by R. C. Schultz, pp. 290-319. Lea and Febiger, 1979. Philadelphia.
54.
Rothman, Richard H. and Wiesel, Sam W.: Acute Low Back Pain - An Objective
Analysis of Conservative Therapy. Clin Orthop 143:290, 1979.
55.
Rothman, Richard H. and Wiesel, Sam W.: Cauda Equina Syndrome. Clin Orthop
147:234-237, 1980.
56.
Rothman, Richard H. and Wiesel, Sam W.: Acute Low Back Pain. Spine 5:6-13, 1980.
57.
Rothman, Richard H. et al: Low Back Pain and Sciatica Following Total Hip
Replacement. Spine 5:292, 1980.
58.
Rothman, Richard H. et al: An Algorithm for the Radiographic Evaluation of Low Back
Pain in Radiographic Evaluation of the Spine edited by J. D. Post. pp. 680-685, 1980.
59.
Rothman, Richard H. et al: Metrizamide Myelography and the Identification of
Anomalous Lumbosacral Nerve Roots. J Bone Joint Surg 62-A, 1203-1208, 1980.
60.
Rothman, Richard H. et al: Arterial Vascularization of the Cauda Equina. J Bone Joint
Surg 63-A, 53-62, 1981.
61.
Rothman, Richard H. et al: Algorithm for Salvage Surgery. Clin Orthop 154:14-17, 1981.
62.
Rothman, Richard H.: The Role of Spine Fusion. Spine 6:7-8. 1981.
63.
Rothman, Richard H. et al: Lumbar Disc Disease and Spinal Stenosis in Surgery of the
Musculoskeletal System. Ed. C. M. Evarts, Churchill Livingston, 1983.
64.
Rothman, Richard H. et al: Fibrous Dysplasia. Skeletal Radiology. (In Press).
65.
Rothman, Richard H. et al: Treatment of Dural Tears. J Bone Joint Surg 63-A, 11321137, 1981.
9
66.
Rothman, Richard H.: Failures of Spinal Surgery. Clin Orthop Surgery Japan. 16, 343348, 1981.
67.
Rothman, Richard H.: Metrizamide Myelography and Epidural Venography. Spine 7:5564, 1982.
68.
Rothman, Richard H. and Holmes, H.E.: The Treatment of the Young Person with a
Herniated Disc. Controversies in Orthopaedic Surgery, Chapter XV. Edited by Leach et
al, W. B. Saunders, 1982.
69.
Rothman, Richard H. et al: Diagnosis and Management of Cervical Spine Injuries.
Athletic Injuries to the Head, Neck and Face, Chapter XIII. Edited by J. S. Torg, Lea and
Febiger, 1982.
70.
Rothman, Richard H. et al: The Detection and Prevention of Pulmonary Embolism in
Total Hip Replacement. J Bone Joint Surg 64-A, 1040-1044, 1982.
71.
Rothman, Richard H. and Bell, G.: The Conservative Treatment of Sciatica. Spine 9:5456, 1984.
72.
Rothman, Richard H. and Holmes, H.: Lumbar Disc Disease - Clinical and CT
Evaluation.
73.
Rothman, Richard H. et al: The Effect of Thermal Therapy upon Rehabilitation of Total
Knee Arthroplasty. Clin Orthop 178:198-201, 1983.
74.
Rothman, Richard H. and Garfin, S.: Traumatic Spondylolisthesis of the Axis. The
Cervical Spine edited by Bailey, p. 223-232. J. B. Lippincott, 1983.
75.
Rothman, Richard H. and Parke, W. W.: The Pharyngovertebral Veins: An Anatomic
Rational for Grisel's Syndrome. J Bone Joint Surg 66-A: 568-574, 1984.
76.
Rothman, Richard H. and Simeone, F.: Clinical Usefulness of CT Scanning in the
Diagnosis and Treatment of Lumbar Spine Disease. Radiol Cl N Am 21, 2:197-200,
1983.
77.
Rothman, Richard H. and Booth, R.: Spinal Stenosis in Modem Trends in Orthopaedic
Surgery. E. M. Campanacci, 1983.
78.
Rothman, Richard H., Wiesel, Sam W. and Feffer, Henry, L.: Industrial Low Back Pain.
Spine 9:199-203, 1984.
79.
Rothman, Richard H. and Herkowitz, H.: Subacute Instability of the Cervical Spine.
Spine 9:348-357, 1984.
10
80.
Rothman, Richard H., Booth, R.E. and Stambough, J.L.: Transient Hypercorticism after
Epidural Steroid Injection. J Bone Joint Surg 66-A: 1115-1116, 1984.
81.
Rothman, Richard H. et al: A Study of Computer Assisted Tomography. Spine
9:552-556, 1984.
82.
Rothman, Richard H. and Cuckler, J.M.: Lumbar Spondylolisthesis in
Neurosurgery. Edited by Wilkens and Rangachari. McGraw-Hill, New York, 1985.
83.
Rothman, Richard H. et al: The Use of Epidural Steroids in the Treatment of Lumbar
Radicular Pain. J Bone Joint Surg 67-A, 63-66, 1985.
84.
Rothman, Richard H.; Wiesel, Sam W. et al: The Development of a Cervical Spine
Algorithm and its Prospective Application to Industrial Patients. J Occ Med 27:272-276,
1985.
85.
Rothman, Richard H. et al: Degenerative Spondylolisthesis. Spine 10:287-289, 1985.
86.
Rothman, Richard H. et al: The Incidence, Clinical Significance & Etiologic Factors
Influencing Aseptic Loosening after Charnley Total Hip Arthroplasty. Univ of Pa Orth
Journal 1:61, 1985.
87.
Rothman, Richard H. et al: Instrapinal Synovial Cysts. J Bone Joint Surg 67-A, 865-871,
1985.
88.
Rothman, Richard H.; Wisneski, R. J.: The Pennsylvania Plan II: An Algorithm for the
Management of Lumbar Degenerative Disease. Chapter 3 in AAOS Instructional Course
Lectures. 17-36, C. V. Mosby, 1985.
89.
Rothman, Richard H. et al: Editorial: CT Scanning and Metrizamide Myelography. Spine
11: 1, p. 1, 1986.
90.
Rothman, Richard H. et al: Aseptic Loosening after Total Hip Arthroplasty. J
Arthroplasty 1:99-107, 1986.
91.
Stambough, Jeffery L.; Rothman, Richard H.; Balderston, Richard A.; Booth, Robert E.
and Cohn, Joy C.: Conversion Total Hip Replacement: A Review of 140 Hips With Over
6 Years Followup. J Arthroplasty 1: 261-269, 1986.
92.
Rothman, Richard H. et al: Sciatica from a Sciatic Neurilemoma. J Bone Joint Surg 68A,
9, 1456-1457, 1986.
93.
Rothman, Richard H.; Wong, R.Y.; and Lotke, P.A.: Bilateral Total Knee
Arthroplasty: A Comparison of Paired Total Condylar and Posterior Stabilized Prosthesis
in Total Arthroplasty of the Knee. p. 274-278. Ed. J. A. Rand and L. D. Dorr, 1987.
11
94.
Rothman, Richard H.: Decision Making in Low Back Surgery. Bul Hosp Joint Diseases
46:93-107, 1986.
95.
Rothman, Richard H. et al: Who Should Receive a Prosthetic Hip? Diagnosis 49-58,
1987.
96.
Rothman, Richard H.; Herkowitz, H. et al: The Use of Computerized Tomography in
Evaluating Non-Visualized Vertebral Levels.... J Bone Joint Surg 69-A, 218-224, 1987.
97.
Rothman, Richard H., et al: Antibiotic Penetration into Rabbit Nucleus Pulposus. Spine
12:254-256, 1987.
98.
Rothman, Richard H. et al: Treatment of the Septic Hip with Total Hip Arthroplasty. Clin
Orthop 221: 231-237, 1987.
99.
Rothman, Richard H.: Cost Control: A Surgeon's Perspective. Trans of College of Phys
of Phila 5:164, 1987.
100.
Rothman, Richard H. et al: The Treatment of Patellar Fractures after Total Knee
Arthroplasty. Jeff Orthop J 16:36-40, 1987.
101.
Rothman, Richard H. et al: Dislocated Total Knee Arthroplasty. Jeff Orthop J 16:77-79,
1987.
102.
Rothman, Richard H. et a]: Posttraumatic Gluteal Compartment Syndrome. Clin Orthop
231:127-129,1988.
103.
Rothman, Richard H.: The Replacement Surgery Option (Editorial) AIM, p. 26, 1988.
104.
Rothman, Richard H. et al: Development and Five Year Prospective Application of a
Computerized Quality Based Diagnostic and Treatment Protocol. J Spinal Disorders
1:50-59, 1988.
105.
Rothman, Richard H. et al: Pulmonary Embolism After Hip or Knee Replacement;
Postoperative Changes on Pulmonary Scintograms in Asymptomatic Patients. Radiology
172 172:481-485, 1989.
106.
Rothman, Richard H. et al: The Prevention of Pulmonary Emboli in Total Hip
Arthroplasty; Ten Year Experience with Low Dose Warfarin Therapy. J Arthroplasty
4:217-221, 1989.
107.
Rothman, Richard H.; Hozack, W.H. et al: Survivorship Analysis of 1,041 Charnley Low
Friction Arthroplasties. J Arthroplasty 5:1, 41-47, 1990.
108.
Rothman, Richard H.; Vemace, J. et al: The Results of Chamley Low Friction
Arthroplasty for Avascular Necrosis. Acta Orthop Scand.
12
109.
Rothman, Richard H. et al: The Treatment of Patellar Fractures after Total Knee
Arthroplasty. Clin Orthop 236:123-128, 1988.
110.
Rothman, Richard H. et al: Laminectomy: A Review of the Pennsylvania Hospital
Experience. J. Spinal Disorders. 1:116-133,1988.
111.
Rothman, Richard H. et al: Dislocation of the Posterior Stabilized Total Knee
Arthroplasty. J. of Arthroplasty 3:363-367, 1988.
112.
Rothman, Richard H. and Garfin, S.R.: Traumatic Spondylolisthesis of the Axis.
Chapter in The Cervical Spine, p. 344-354, J. B. Lippincott, 1989.
113.
Rothman, Richard H. and Wisneski, R.: Microdiscectomy Techniques. Seminars in Spine
Surgery 1:54-59, 1989.
114.
Rothman, Richard H. et al: Long Term Results of Lumbar Spine Surgery Complicated by
Unintended Incidental Durotomy. Spine 14:443-446, 1989.
115.
Rothman, Richard H. et al: The Patellar Clunk Syndrome. Clin Orthop 241:203208,1989.
116.
Rothman, Richard H. et al: Arthroscopic Management of the Patellar Clunk
Syndrome following Posterior Stabilized Total Knee Arthroplasty. J Arthroplasty
4:179-182,1989.
117.
Rothman, Richard H. et al: Errors in Decision Making as a Cause for Failure of Lumbar
Surgery, Chapter in Complications of Spine Surgery. Edited by S. Garfin, M. D.,
Williams and Wilkins, Baltimore, 1989.
118.
Rothman, Richard et al: Microdiscectomy: A Critique in Microdiscectomy of the
Lumbar Spine. Edited by Williams, McCullough and Young, Aspen, Baltimore, 1990.
119.
Rothman, Richard H. and Cohn, J.: Cemented Versus Cementless Total Hip
Arthroplasty. Clin Orthop 254:153-169, 1990.
120.
Rothman, Richard H. et al: Lumbar Spine Algorithm in the Lumbar Spine. Edited by
Weinstein and Wiesel. W. B. Saunders, Philadelphia, PA 1990.
121.
Rothman, Richard H.; Lotke, P., et al: Bilateral Total Knee Arthroplasty: A comparison
of Paired Total Condylar and Posterior Stabilized Prostheses. Chapter 21 in Proceedings
of the Knee Society, 1985, J. Rand Ed., Aspen and Baltimore, 1987.
122.
Rothman, Richard H. et al: Long Term Survival of the Charnley Low Friction Total Hip
Arthroplasty. Seminars in Arthroplasty 1:3-7, 1990.
13
123.
Rothman, Richard H., et al; Initial Stability of a Collarless Wedge Shaped Prosthesis in
the Femoral Canal. Seminars in Arthroplasty 1:87-91, 1990.
124.
Rothman, Richard H. et al Insertional Femoral Fracture: A Biomechanical Study of
Femoral Component Stability. Seminars in Arthroplasty 1:91-95, 1990.
125.
Rothman, Richard H. et al: Radiographic Demarcation of the Acetabular Bone-Cement
Interface. J Arthroplasty 5:1-4, 1990.
126.
Rothman, Richard H. et al: Total Knee Arthroplasty After Tibial Osteotomy. Seminars in
Arthroplasty 2:53-59, 1990.
127.
Rothman, Richard H. et al: Total Hip Arthroplasty for Osteonecrosis. Seminars in
Arthroplasty 2:3, 234-240, 1991.
128.
Rothman, Richard H. et al: The Technique of Cemented Total Hip Arthroplasty.
Techniques Orthop 6:26-33, 1991.
129.
Rothman, Richard H. et al: Evaluation of the Painful Prosthetic Joint. J Arthroplasty
6:237-244, 1991.
130.
Rothman, Richard H. et al: Clinical and Roentgenographic Evaluation of HydroxyapatiteCoated and Uncoated Porous Total Hip Arthroplasty. Seminars in Arthroplasty 2:280288, 1991.
131.
Rothman, Richard H. et al: Rotation Affects Apparent Radiographic Position of Femoral
Components in Total Hip Arthroplasty. J Arthroplasty 6:567-571, 1991.
132.
Rothman, Richard H. et a]: Patient Controlled Analgesia in a Postoperative Total Joint
Arthroplasty Population. J Arthroplasty 6:523-528, 1991.
133.
Rothman, Richard H. et al: Femoral Neuropathy Following Total Hip Arthroplasty. J
Arthroplasty 6:559-566, 1991.
134.
Rothman, Richard H. et al: A Prospective Comparative Study of Cemented vs.
Cementless Total Hip Arthroplasty. Jeff Orthop J 20:25-34, 1991.
135.
Rothman, Richard H. et al: Trochanteric Non-unions. Jeff Orthop J 20:35-38, 1991.
136.
Rothman, Richard H. et al: Operative Technique for Primary Total Hip Replacement Chapter in The Hip, Lea and Febiger, 199 1.
137.
Rothman, Richard H. et al: Uncemented Total Hip Arthroplasty. Chapter in The Hip, Lea
& Febiger, 1991.
14
138.
Rothman, Richard H. et al: Infections in Total Hip Replacement. Chapter in The Hip,
Lea & Febiger, 1991.
139.
Rothman, Richard H. et al: Total Knee Replacement, Arterial Complications. Am J Surg
164:237-240, 1992.
140.
Rothman, Richard H. et al: Exclusion of Type 11 and Type VI Pro Collagen Gene
Mutatons in a Five Generation Family with MED.
141.
Rothman, Richard H. et al: Primary Total Knee Arthroplasty for Displaced Acute Intraarticular Knee Fractures. Clin Orthop 276:229-237, 1992.
142.
Rothman, Richard H. et al: Intraoperative Femoral Fractures in Cementless Total Hip
Arthroplasty. Orthop Review 21:337-342, 1992.
143.
Rothman, Richard H. et al: Posterior Dislocation of Total Knee Arthroplasty. Clin Orthop
278:128-133, 1992.
144.
Rothman, Richard H. et al: Pulmonary Embolism in Total Hip and Knee Arthroplasty.
Clin Orthop 282:158-163, 1992.
145.
Rothman, Richard H. et al: A Prospective Randomized Comparison of Two Surgical
Approaches to Total Hip Arthroplasty. Clin Orthop 288:102-111, 1993.
146.
Rothman, Richard H. et al: Pulmonary Embolism - Incidence in Primary Cemented and
Uncemented Total Hip Arthroplasty. J Arthroplasty 7:465-470, 1992.
147.
Rothman, Richard H. et al: Incidence of Pulmonary Embolism after Total Knee
Arthroplasty...Clin Orthop 286:27-31, 1993.
148.
Rothman, Richard H. et al: TGF Enhances Osseointegration In Vivo. Proceedings of the
6th International Symposium on Ceramics in Medicine. P. Duchenne, Ed. 1993.
149.
Rothman, Richard H. et al: Porous Coating Methods: The Pros and Cons. Contemp
Orthop 27:269-278, 1993.
150.
Rothman, Richard H. et al: Cemented vs. Cementless Total Hip Replacement - A
Comparative Study of Equivalent Patient Populations. Clin Orthop 289:161-165, 1993.
151.
Rothman, Richard H. et al: Establishing a Home Care Protocol for Early Discharge of
Patients with Hip and Knee Arthroplasties. Home Healthcare 12:24-30, 1994.
152.
Rothman, Richard H. et al: Radiographic Assessment of Cementless Femoral
Components. J Arthroplasty 9:137-141, 1994.
15
153.
Rothman, Richard H. et al: Hip Arthroplasty: Fit and Fill, Fact or Fiction? Orthop 17:803,
1994.
154.
Rothman, Richard H. et al: Establishing a Home Care Protocol for Early Discharge of
Patients with Hip and Knee Arthroplasties. Home Healthcare 12:24-30, 1994.
155.
Rothman, Richard H. et al: Acute Arterial Thrombosis Associated with Total Knee
Arthroplasty. Journal of Vascular Surgery, 20, 927-932, 1994.
156.
Rothman, Richard H. et al: Post-operative Blood Salvage in Total Knee Arthroplasty
Using the Solcotrans Autotransfusion System. J. Arthroplasty 10:433-437, 1995.
157.
Rothman, Richard H. et al: Prospective Randomized Evaluation of Blood Salvage
Techniques for Primary Total Hip Arthroplasty. J. Arthroplasty 10:532-539, 1995.
158.
Rothman, Richard H. et al: Comparison of Cemented and Cementless Total Hip
Arthroplasty in Patients with Bilateral Hip Arthroplasties. J. Arthroplasty 10:603-608,
1995.
159.
Rothman, Richard H. et al: Continuous Passive Motion After Total Knee Arthroplasty.
Clin Orthop 321:208-215, 1995.
160.
Rothman, Richard H. et al: Catastrophic Failure of Modular Zirconia Ceramic Femoral
Head Components after Total Hip Arthroplasty: A Report of Two Cases. J Arthroplasty
10:848-850, 1995.
161.
Rothman, Richard H. et al: Predicting Quality of Life Outcomes Following Total Joint
Arthroplasty: Limitations of the SF-36. J Arthroplasty 10:742-747, 1995.
162.
Rothman, Richard H. et al: Thiazide Induced Hyponatremia in the Postoperative Total
Joint Replacement Patient. Contemp Orthop 1995 (in press.).
163.
Rothman, Richard H. et al: The Incidence of Thigh Pain After Uncemented Femoral
Prosthesis as a Function of Femoral Stem Size. J Arthroplasty 11:304-311, 1996.
164.
Rothman, Richard H. et al: Radiographic Cost Reduction Strategy in Total Joint
Arthroplasty: A Prospective Analysis. J Arthroplasty 1 1:277-280, 1996.
165.
Rothman, Richard H. et al: Hydroxyapatite-Coated Femoral Stems: A Matched Pair
Analysis. J Bone Joint Surg 78-8, 319-324, 1996.
166.
Rothman, Richard H. et al: Heterotopic Ossification: Incidence in Cemented vs.
Cementless Total Hip Arthroplasty. J Arthroplasty 11:58-63, 1996.
16
167.
Rothman, Richard H. et al: Comparative Risk of Early Pulmonary Embolism after
Cemented Total Knee Versus Total Hip Arthroplasty with Low Dose Coumadin
Prophylaxis. Am J Knee Surg 9:2-6, 1996.
168.
Rothman, Richard H. et al: Head Neck Modularity for Total Hip Arthroplasty. J
Arthroplasty 11:397-399, 1996.
169.
Rothman, Richard H. et al: The Treatment of Early Symptomatic Pulmonary Embolism
After Total Joint Replacement. J Arthroplasty 11: 522-525, 1996.
170.
Rothman, Richard H. et al: Osteoarthritis of the Hip - A Surgical Approach. Am J.
Managed Care 2:1111-1114, 1996.
171.
Rothman, Richard H. et al: Relationship Between Polyethylene Wear, Pelvic Osteolysis
and Clinical Symptomatology. J. Arthroplasty 11:769-772, 1996.
172.
Rothman, Richard H. et al: Primary Cementless Hip Arthroplasty with Titanium Plasma
Sprayed Prosthesis. Clin Orthop 333:217-225, 1996.
173.
Rothman, Richard H. et al: Relationship of Total Hip Outcome Studies to Other
Orthopedic Procedures. Clin Orthop 344:88-93, 1997.
174.
Rothman, Richard H. et al: Simultaneous Bilateral Versus Unilateral Total Knee
Arthroplasty: Outcomes Analysis. Clin Ortho 345:106-112, 1997.
175.
Rothman, Richard H. Editoral - All Change is Not Progress. J. Arthroplasty 13:121-122,
1998.
176.
Rothman, Richard H.: Can Groin Pain Be Eliminated in a Conversion Arthroplasty. J.
Arthroplasty 13:627-630, 1998.
177.
Rothman, Richard H.: Treatment of Failed Cementless Components.
178.
Rothman, Richard H., et al.: Immediate Weight Bearing After Uncemented Total Hip
Arthroplasty. Clin. Orth 349:156-162, 1998.
179.
Rothman, Richard H. et al.: Minimum 10 Year Results of a Tapered Cementless Total
Hip Replacement. Accepted for Clinical Orthopaedics, 1998.
180.
Rothman, Richard H. et al: Factors Influencing Choice of Implants in Total Hip
Arthroplasty and Total Knee. J Arthroplasty 14:281-287, 1999.
181.
Rothman, Richard H. et al: Total Hip Arthroplasty in Patients on Long Term Renal
Dialysis. J Arthroplasty 14, 1999.
17
182.
Rothman, Richard H. et al: Uncemented Total Hip Arthroplasty in Pagets Disease of the
Hip. J. Arthroplasty 14: 872-875, 1999.
183.
Rothman, Richard H. et al: Disability Related to Disorders of the Foot and Ankle. J. Of
Disability 8:19-24, August 1999.
184.
Rothman, Richard H. et al: Femoral Revision Hip Arthroplasty. Operative Techniques
in Orth, 10:133-137, 2000.
185.
Rothman, Richard H. et al: Effects of Femoral Component Offset on Polyethylene Wear
in Total Hip Arthroplasty. Clinical Orthopaedics and Related Research 387: 000-000,
2001.
186.
Rothman, Richard H. et al: Pseudoaneurysm of the Femoral Artery. J Arthroplasty
15:531-534, 2000.
187.
Rothman, Richard H. et al: Primary Cementless Total Hip Arthroplasty in
Octogenarians. J Bone Joint Surg 83-A:359-363, 2001.
188.
Rothman, Richard H. et al: Cementless Femoral Fixation in the Rheumatoid Patient. J
Arthroplasty 16:415-421, 2001.
189.
Rothman, Richard H. et al: Total Hip Arthroplasty Using Two Different Cementless
Tapered Stems. Clin Orthop Related Research, 393:121-127, 2001.
190.
Rothman, Richard H. et al: Fixed Minidose Versus Adjusted Low Dose Warfarin after
Total Joint Arthroplasty. J. Arthroplasty 16: 1030-1037, 2001.
191.
Rothman, Richard H. et al:. Why are Total Knee Arthroplasties Failing Today? Insall
Award Paper. Clin Orthop Rel Research 404:7-13, 2002.
192.
Rothman, Richard H. et al.: Ten to Fifteen-Year Follow-up After Total Hip Arthroplasty
with a Tapered Cobalt-Chromium Femoral Component (Tri-Lock) Inserted without
Cement. J Bone Joint Surg 84A(12):2140-2144, 2002.
193.
Rothman, Richard H. et al: Stability and Leg Length Equality in Total Hip Arthroplasty.
J. Arthroplasty, 18, 88-90, 2003.
194.
Rothman, Richard H. et al: Early Failure Mechanisms of Constrained Acetabular
Sockets. J. Arthroplasty, 18: 827-833, 2003.
195.
Parvizi J, Martel JM, Shubert MA, Sharkey PF, Hozack WJ, Rothman RH. Ear
Performance of Highly Cross-Linked Polyethylene Liner Versus Standard Polyethylene
Liner in Bilateral Total Hip Arthroplasty. Submitted to J Bone Joint Surg October 2003.
18
196.
Parvizi J, Bissett G, Hozack WJ, Sharkey PF, Rothman RH: Surgical Treatment of Limb
Length Discrepancy Following Total Hip Arthroplasty. J Bone and Joint Surg,85A:12pp
2310-2317, 2003.
197.
Parvizi J, Keisu KS, Hozack WJ, Sharkey PF, Rothman RH. Primary Total Hip
Arthroplasty with An Uncemented Femoral Component: A Long Term Study of the
Taperloc Stem. J Arthroplasty 19(2):151-156, 2004.
198.
Austin MS, Sharkey PF, Hozack WJ, Rothman RH. Knee Failure Mechanisms after
Total Knee Arthroplasty. Techniques in Knee Surgery, 3(1):55-59, 2004.
199.
Pavizi J, Sharkey PF, Hozack WJ, Orzoco F, Bissett GA, Rothman RH. Prospective
Matched-Pair Analysis of Hydroxyapatite-Coated and Uncoated Femoral Stems in Total
Hip Arthroplasty. A Concise Follow-up of a Previous Report. J Bone Joint Surg
86A(4):783-786, 2004.
200.
Rothman RH, et al. Prospective Matched Pair Analysis of Hydroxyapatite-coated and
Uncoated Femoral Stems in Total Hip Arthroplasty. JBJS 86-A, 783-786, 2004.
201.
Peter F. Sharkey MD, H. David Homesley MD, Shani Shastri MD, Sidney M. Jacoby
BA, William J. Hozack MD, Richard H. Rothman, MD, PhD. Results of Revision Total
Knee Arthroplasty After Exposure of the Knee with Extensor Mechanism Tenolysis. J.
Arthroplasty, Volume 19, Issue 6, Pages 751-756, September 2004.
202.
Matthew S. Austin MD, Gregg R. Klein MD, Peter F Sharkey MD, William J. Hozack
MD, Richard H. Rothman MD, PhD. Late Sciatic Nerve Palsy Caused by Hematoma
After Primary Total Hip Arthroplasty. J. Arthroplasty, Volume 19, Issue 6, Pages 790792, September 2004.
203.
Peter F. Sharkey MD, Shani Shastri MD, Marco A. Teloken MD, Javad Parvizi MD,
William J. Hozack MD, Richard H. Rothman MD, Ph.D. Relationship Between Surgical
Volume and Early Outcomes of Total Hip Arthroplasty. J. Arthroplasty, Volume 19,
Issue 6, Pages 694-699, September 2004.
204.
Klein GR, Parvizi J, Sharkey PF, Rothman RH, Hozack WJ: Minimally Invasive Total
Hip Arthroplasty Internet Claims Made by Hip Society Members. The Hip Society,
October 2004, Santa Fe, NM.
205.
Parvizi J, Wickstrom E, Zeiger AR, Adams CS, Shapiro IM, Purtill JJ, Sharkey PF,
Hozack WJ, Rothman RH, Hickok NJ. Frank Stinchfield Award. Titanium Surface with
Biologic Activity Against Infection. Clin Orthop Rel Research 429:33-38, 2004.
206.
Parvizi J, Rapuri VR, Purtill JJ, Sharkey PF, Rothman RH, Hozack WM. Treatment
Protocol for Proximal Femoral Periprosthetic Fractures. J Bone Joint Surg, 86A: 8-16,
2004.
19
206.
Parvizi J, Sharkey PF, Hozack WJ, Orzoco F, Bissett GA, Rothman RH. Outcome of
Hydroxyapatite-Coated Femoral Stems. A Prospective Matched-Pair Analysis of Coated
and Uncoated Implants. J. Bone Joint Surg (A). 86-A(4): 783-786, 2004.
207.
Peak EL, Parvizi J, Ciminello M, Purtill JJ, Sharkey PF, Hozack WJ, Rothman RH. The
Role of Patient Restrictions in Reducing the Prevalence of Early Dislocation following
Total Hip Arthroplasty. J. Bone Joint Surg 87-A(2) 247-253, 2005.
207.
Peak EL, Hozack WJ, Sharkey PF, Parvizi J, Rothman RH. One-Stage Bilateral Total
Hip Arthroplasty: A Prospective and Comparative Study Between Total Hip and Total
Knee Replacement. Accepted to Orthopaedics March 2005.
208.
Kurtz SM, Hozack WJ, Turner J, Purtill JJ, MacDonald D, Sharkey PF, Parvizi J, Manley
R, Rothman RH. Mechanical Properties of Retrieved Highly Cross-Linked Crossfire
Liners After Short-Term Implantation. J. Arthroplasty, 20(7): 840-849, 2005.
209.
Rothman RH, et al. Total Hip Arthroplasty in Patients With Developmental Dysphasia.
Seminars in Arthroplasty (In Press).
210.
Rothman RH, et al. How To Write a Successful Manuscript. China Orthopaedics, 2:49,
2005.
211.
Klein GR, Parvizi J, Sharkey PF, Rothman RH, HozackWJ: Minimally Invasive Total
Hip Arthroplasty: Internet Claims Made by Members of the Hip Society. Clin Orthop
Rel Research 441:68-70, 2005.
212.
Rothman RH, et al: Management of Arthritis of the Hip in The Young Adult. JBJS
88-B, 1279-1285, 2006.
213.
Rothman RH, et al: Bilateral Total Hip Arthroplasty – Clinical Orthopaedics,
453, 137-141, 2006.
214.
Rothman RH, et al: Total Hip Arthroplasty for Acute Femoral Neck Fractures. Journal
of Arthroplasty, 21:1134-1140, 2006.
215.
Rothman RH, et al: Total Joint Arthroplasty: When do Fatal or Near Fatal Complications
Occur? JBJS 89A:27-32, 2007.
216.
Rothman RH, et al: Clinical Experience Using a Minimally Invasive Approach for Total
Knee Arthroplasty. Journal of Arthroplasty 22:8-13, 2007.
21.7
Rothman RH, et al: Can Epidural Anesthesia and Warfarin be Co-Administered? Clin
Orthop Rel Research 456:133-137, 2007.
218.
Rothman RH, et al: The Role of Minimally Invasive Hip Surgery in Reducing Pain.
AAOS Inst. Course Lect. 56: 121-124, 2007.
20
219.
Rothman RH, et al: Uncemented Total Hip Arthroplasty in Patients with a History of
Pelvic Irradiation…JBJS 89:798-805, 2007.
220.
Rothman RH, et al: Diet, Obesity, Nutrition and their Role in Arthritis. Seminars in
Arthroplasty, 117-121, 2007.
221.
Rothman RH, et al: The Inferior Vena Cave Filter is Effective in Preventing Fatal
Pulmonary Embolism. Journal of Arthroplasty 22:343-348, 2007.
222.
Rothman RH, et al: Minimally Invasive Hip Arthroplasty: What Role Does Patient
Preconditioning Play? JBJS Volume 89-A No. 9 Pgs. 1920-1927 – September, 2007.
223.
Rothman RH, et al: Does Excessive Anticoagulation Pre-dispose to Periprosthetic
Infection? Journal of Arthroplasty 22, Sup. 2, 24-28, 2007.
224.
Rothman RH, et al: The Rise in the Incidence of Pulmonary Embolism after Total Joint
Arthroplasty. Clinical Orthopaedics 463, 107-113, 2007.
225.
Rothman RH, et al: Primary Total Hip Arthroplasty with an Uncemented Femoral
Component: Two-to Seven-Year Results. Journal of Arthroplasty Vol. 22, No. 7,
Suppl. 3 – Pgs. 43-46, 2007.
226.
Rothman RH, et al: Post-Operative Ileus After Total Joint Arthroplasty. Journal of
Arthroplasty, 23:360-365, 2008.
227.
Rothman RH, et al: The Noisy Ceramic Hip: Is Component Malpositioning the Cause?
Journal of Arthroplasty, 23, 643-649, 2008.
228.
Rothman RH, et al: Deep Venous Thromboses Prophylaxis for Total Joint Arthroplasty.
Journal of Arthroplasty, 23: 2-5, 2008.
229.
Rothman RH, et al: Hypoxemia After Total Joint Arthroplasty. Journal of Arthroplasty,
23: 1016-1021, 2008. Journal of Arthroplasty, 23: 1016-1021, 2008.
230.
Rothman RH, et al: Vascular Injuries after Total Joint Arthroplasty. Journal of
Arthroplasty. 23: 1115-1121, 2008.
Text Books:
1.
The Intervertebral Disc: co-authored with DePalma, Anthony, F., W. B. Saunders, 1970.
2.
The Spine: Volumes I and II co-authored with Simeone, F. A., W. B. Saunders, 1975.
3.
The Aging Spine: co-authored with Wiesel, Sam W. and Bemini, Philip M., W.B.
Saunders, 1982.
4.
The Spine: Second Edition Volumes I and II co-authored with Simeone, F.A., W. B.
Saunders, 1982.
21
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
Industrial Low Back Pain: co-authored with Wiesel, S. W.and Feffer, H. L. Michie Co.,
1985.
Lumbar Spine Surgery - Techniques and Complications: White, Rothman and Ray, C. V.
Mosby,1988.
Total Hip Arthroplasty: Rothman, Richard H. et al. W. B. Saunders, 1988.
Complications of Total Hip Arthroplasty: Rothman, Richard H. et al, W. B. Saunders,
1988.
Neck Pain: Rothman, R.H. et al. Michie Co., 1986.
The Hip: Balderston, R.A., Rothman, R.H., and Booth, R. E. Lea and Febiger, 1991.
Low Back Pain, Second Ed.: Rothman, R. H. et al. Michie Publishing Co., 1989.
The Aging Spine. Rothman, R. H. et al. W. B. Saunders, 1991.
The Spine: Third Edition, Vol. I & II, W. B. Saunders, 1991.
Low Back Pain: Second Edition, Michie Publishing Co., 1996.
Low Back Pain, Lexis Publishing, 1997.
Symposia.
Diseases of the Intervertebral Disc: Rothman, Richard H., W. B. Saunders, 1971.
The Shoulder: Rothman, Richard H., W. B. Saunders, 1975.
The Lumbar Spine: Rothman, Richard H., W. B. Saunders, 1977.
Audio-Visual Programs:
Sound-Slide Program for the American Academy of Orthopaedic Surgeons
Myelographic Patterns in Lumbar Disc Degeneration, 1975.
Operative Treatment of Lumbar Disc Disease, Orthopedic Audio-Synopsis Foundation,
1977.
American College of Surgeons Clinitapes,
Current Concepts in the Treatment of Low Back Pain, 1977.
Research Grants:
The Effect of Anemia on Fracture Healing, AM12978.
Richard H. Rothman - Principle Investigator, National Institutes of Health.
Training Grants:
Post-Graduate Training Grant in Orthopaedic Surgery AM05518.
Richard H. Rothman, Co-Director National Institutes of Health.
Present Research Activities:
This investigator has had his primary basic research training and experience in the study
of degenerative changes in connective tissue. The relationship of these changes to blood
22
flow has been studied in bone, tendon, and articular cartilage with aging and
osteoarthritis. Use has been made of both laboratory models and human clinical material.
In the realm of clinical research his major emphasis has been on the study of degenerative
disease of the spine as well as degenerative arthritis of the hip and knee. Anatomic and
pathologic studies have been performed to expand the body of knowledge in these areas
of the skeleton in normal and diseased states. This knowledge has then been related to
new methods of surgical treatment of the age-related disorders of the spine, hip and knee.
A continuum of research has also been established on the new and evolutionary
diagnostic modalities used to study the spine, hip and knee with clinical pathologic
correlations.
Current Basic Science Research Proiects:
Studies are being performed on the changes in connective tissue, biochemical
composition of the intervertebral disc and articular cartilage with aging and variational
stress.
Anatomic studies are being conducted on the gross and microvasculature supplying the
spinal cord and Cauda Equina. The relationship of this blood supply to pathologic
disease states is also being evaluated.
A laboratory model of osteoarthritis has been produced in the canine and rabbit knee with
subsequent evaluation of the changes in vascular bed and blood flow.
A major bioengineering project is currently being conducted on the initial fixation of
uncemented hip implants in cadaver femora. Using an Instron testing device both axial
and rotational fixation is being evaluated with a variety of hip implants as a measure of
fixation strength and safe parameters for fixation forces. Instrumentation is being
developed to allow In vivo measurements of both torque and axial fixation to improve the
degree of operative stability achieved.
A series of experiments are being conducted to study the cellular function at the interface
between uncemented implants and adjacent bone in laboratory animals. A variety of
stimuli are being evaluated to better understand the processes related to bony ingrowth.
The effect of a variety of anticoagulants including aspirin, Coumadin, and Heparin are
also being studied in regard to porous ingrowth.
Current Clinical Research Projects:
A randomized prospective evaluation of lumbar spine surgery for degenerative diseases
of the spine to evaluate decompression, fusion, and the use of interposition membranes is
being conducted.
A correlative study of MRI and CT scanning is being conducted in terms of evaluation of
lumbar spinal stenosis and lumbar disc herniation in conjunction with the Department of
Radiology.
23
The effectiveness of low dose Coumadin is being evaluated to prevent thromboembolic
complications of hip reconstruction.
An FDA approved investigational study is being conducted on the use of Gentamicin
impregnated methylmethacrylate in the treatment of infected total hip replacements.
An FDA approved study is being performed evaluating uncemented femoral prostheses
and their effectiveness in the treatment of degenerative arthritis of the hip.
A major long term prospective study of all total hip and Knee replacements performed at
Pennsylvania Hospital and Thomas Jefferson University Hospital is being performed.
A series of studies is being conducted in regard to the factors affecting long term
loosening in cemented hip implants. These include femoral head size, cement technique
about the socket, and extreme age. Survivorship analysis is being studied in regard to all
of these parameters in an effort to ascertain their effect.
Intensive review of all of those patients who have developed either symptomatic or
asymptomatic pulmonary emboli is being conducted to isolate those factors prejudicing
their development of this complication as compared to the large population sub-group
free of thromboembolic disease.
PCA - patient controlled analgesia is being evaluated as a method of pain relief in the
immediate postoperative course after hip replacement surgery.
A prospective randomized study is being conducted to compare the Hardinge approach
versus trochanteric osteotomy. Pain, surgical technique as evaluated by x-ray, and blood
loss are being evaluated. Muscle strength postoperatively is also being evaluated
utilizing Cybex.
A series of outcome studies are being conducted measuring effectiveness of joint
reconstruction on patient independence, emotional well being and social independence.
24