What Determines University Patent Commercialization? Empirical Evidence on the Role of University IPR ownership Paola Giuri, Federico Munari, Martina Pasquini Department of Management, University of Bologna • Financial support from the EC project 217299 InnoS&T and from the EIBURS programme of the EIB (FinKT project) is gratefully acknowledged. Federico Munari – University of Bologna 1 Objectives of the paper 1) Understand whether and how the ownership of IPRs by universities and PROs affects their subsequent commercialization 2) Identify other relevant factors influencing the commercialization of university and PRO patents by considering three exploitation routes: • Patent sale • Licensing • Spin-off formation Empirical evidence from a sample of 858 EPO patents with inventors employed by universities and PROs in 23 countries Federico Munari – University of Bologna 2 Motivations of the study • The need to enhance patent valorization for growth and jobs (EC working document, 2012). • The “Innovation Union” initiative emphasizes the need to improve the economic exploitation of unused IPRs (Europe 2020). • With specific regards to universities and PROs, several reforms over the last two decades have tried to foster the commercialization of research results (Henderson et al., 1998; Wright et al., 2003; Coupe, 2003; Mowery and Ziedonis, 2002; Sapsalis et al. 2006). • Implementation of Bay-Dole like reforms in various European countries moving towards institutional ownership of academic inventions (Rossi and Geuna, 2011) • However, there is little or no empirical evidence assessing the effects of such reforms on the commercial exploitation of university and PRO inventions. Federico Munari – University of Bologna 3 Background Literature: The reforms of University IPRs regimes • In the US, the turning point was the Bayh-Dole Act (1980) • In Europe, several reforms have been introduced since the late 1990s. Most European countries moved towards a system of institutional ownership (e.g. Baldini, 2006; Della Malva et al., 2008; Meyer and Tang, 2007; Geuna and Rossi, 2011) • Significant heterogeneity remains across and within European countries, also due to specific university bylaws. Institutional ownership regime Professors’ privilege regime • The university maintains the ownership of patents resulting from publiclyfunded research • The researcher maintains the ownership of patents resulting from publiclyfunded research • i.e Most European countries • i.e. Italy, Sweden Federico Munari – University of Bologna 4 Literature: university IPR ownership and impact on TT activities Empirical evidence on the consequences of university IPR ownership patterns on the success of technology transfer activities is still limited (Shane, 2001; Crespi et al., 2010). Universityowned patents • Patents generated by an academic inventor and owned by the university employing the academic inventor Universityinvented patents • Patents generated by an academic inventor and not owned by the university employing the academic inventor Federico Munari – University of Bologna 5 Literature: university IPR ownership and the efficacy of TT activities • Both university-invented and university-owned patents have increased (e.g. Baldini, 2006; Della Malva et al., 2008; Meyer and Tang, 2007; Tang, 2008) • A high percentage of academic patents still remained owned by private businesses (Geuna and Rossi, 2011; Lissoni, 2012) • Mixed evidence on the number of forward citations per universityowned patent as compared to company-owned academic patents (Czarnitzki et al., 2011; Lissoni et al., 2010) • The study by Crespi et al. (2010) on a sample of European university and PRO patents from the period 1993-1997 does not find significant evidence of a university ownership effect on the commercialization of patents Federico Munari – University of Bologna 6 Our study: research questions and intended contributions 1) Does the ownership of patents on university or PRO research (university-owned vs. university-invented) impact on the final commercialization outcome? 2) Are there significant differences depending on the type of exploitation route adopted (sale, license, spin-off formation)? 3) Is the relationship between university IPR ownership and commercial exploitation influenced by the type of national IPR legislation on university patents (institutional ownership regime vs. professors’ privilege)? 4) Which other factors (scientific background of the invention, incentive systems, funding sources) affect the commercialization outcome? Federico Munari – University of Bologna 7 Sample • We used data from the PatVal-EU II survey of inventors of EPO patents with priority dates in 2003-2005 in 20 European countries, US, Japan and Israel. • 22,533 responses by the inventors in all surveyed countries in the PatVal-EU II dataset, corresponding to a corrected response rate of 20%. • Of these, 1310 patents (6% of the total) refer to inventors employed in universities or PROs at the time of the invention. • Our final sample is represented by 858 patents (out of 1310) from university and PRO inventors, due to missing information on some covariates. Federico Munari – University of Bologna 8 Sample Distribution of sample patents by affiliation of the inventor Distribution of sample patents by country Affiliation of the inventor University PRO % 63.4 36.6 Total 100% Distribution of sample patents across OST 6 technological sectors Sector Electrical engineering Instruments Chemistry, Pharma Process Engineering, Special Equipment Mechanical Engineering Consumption (Consumer goods, Construction) Total % 17.45 24.06 39.98 9.2 6.13 3.18 Country AT BE CH CZ DE DK ES FI FR GB GR HU IE IL IT JP NL NO PL SE SI US % 0.94% 2.12% 2.36% 0.71% 18.63% 0.94% 2.59% 0.94% 14.98% 6.37% 0.47% 0.24% 1.18% 1.77% 8.37% 15.80% 4.60% 0.35% 0.83% 1.89% 0.94% 12.97% Total 100.00% 100 Federico Munari – University of Bologna 9 Dependent and Explanatory Variables DEPENDENT VARIABLES DEFINITIONS Patent Sale Dummy variable equal 1if the patent has been sold at the time of the survey, and 0 otherwise Patent Licensing Dummy variable equal 1 if the patent has been licensed, and 0 otherwise Spin-off Formation Dummy variable equal 1 if the patent has been used to form a spin-off, and 0 otherwise External Use A dummy variable equal to 1 if the patent has been externally used (sale or license or spin-off), 0 if it was not used EXPLANATORY VARIABLES University-owned patent Dummy variable equal to 1 if the patent was owned by the university that employed the inventor, and 0 otherwise PRO-owned patent Dummy variable equal to 1 if the patent was owned by PRO that employed the inventor, and 0 otherwise PRO-invented patent Dummy variable equal to 1 if the patent was not owned by PRO that employed the inventor, and 0 otherwise Institutional ownership regime Dummy variable equal to 1 if the inventor’s country adopted the institutional ownership regime of university patents, and 0 otherwise Federico Munari – University of Bologna 10 Control Variables -- Inventors’ characteristics: age, experience, number of scientific publications related to the inventions -- Financing resources used to generate the invention: internal resources, EU, VCs, bank loan, suppliers, customers -- Available incentive systems for inventions: influence for promotion, salary increase, one-lump payment. -- Country and technology dummies (5 OST macro sectors) Sources of data: PatVal II survey Federico Munari – University of Bologna 11 Descriptive statistics: main findings • Our descriptive analyses suggest that the share of university/PRO owned patents, as compared to university/PRO invented patents, has significantly increased over the last decade. • However, a large share of university patents in our sample are still not owned by universities (46%). • There is not a large difference between university/PRO owned patens vs. university/PRO invented patents in the overall likelihood of external commercialization (via sale or license or spin-off). • However, the results suggest the need to distinguish the different modes of commercialization in order to more clearly understand the impact of university ownership. In particular, university/PRO ownership seems to be positively associated to licensing. Federico Munari – University of Bologna 12 Descriptive statistics: main findings • Moreover, the analyses suggest that it is important to distinguish universities and PROs, since they seem characterized by different commercialization patterns. • The positive impact of the direct ownership of patents is particularly pronounced in the case of universities. In the subsample of university patents, the commercialization of university-owned patents seems more frequent than for university-invented patents (expecially for what concern the licensing route). Federico Munari – University of Bologna 13 Descriptive results: the ownership patterns of university and PRO patents Patval II Patval II Patval I (Crespi et al., 2010) N. Countries 22 6 6 Priority dates 2003-2005 2003-2005 1993-1997 54% 55% 18% 46% 45% 82% PRO-owned 79% 81% 42% PRO-invented 21% 19% 58% Universityowned Universityinvented Federico Munari – University of Bologna 14 Descriptive statistics: the commercialization of university/PRO patents according to the type of owners All patents (n=858) University/PRO-owned University/PRO-invented University patents (n=521) University-owned University-invented PRO patents (n=337) PRO-owned PRO-invented Non-commercialized Patents Commercialized Patents Sale Licensing Spin-off 66.67% 33.33% 7.65% 25.95% 14.75% 26.86% 11.33% 11.97% 14.89% Commercialized Patents Sale Licensing Spin-off 46.07% 13.21% 34.29% 21.79% 72.71% 27.39% 12.45% 11.62% 14.52% Non-commercialized Patents Commercialized Patents Sale Licensing Spin-off 20.07% 1.90% 15.24% 7.43% 25.00% 7.35% 13.23% 16.17% 73.14% Non-commercialized Patents 53.93% 79.93% 75.00% Multiple answers on type of use were possible. Federico Munari – University of Bologna 15 University IPR ownership regimes in the different countries in the period of the study (2003-2005) Professor’s Privilege Finland Italy Sweden Slovenia Hungary Institutional IPR regime Austria Belgium Czec Republic Denmark France Ireland Israel Japan Poland Switzerland Spain United Kingdom United States Germany Greece Netherlands Source: Geuna and Rossi (2011) Federico Munari – University of Bologna 16 Descriptive statistics: the commercialization of university/PRO patents according to the national regime on university IPRs Non-commercialized Commercialized Patents Patents Institutional Ownership 69.19% Professor’s Privilege All patents (n=858) 30.81% Sale 7.96% Licensing 21.11% Spinoff 14.47% 67.62% 32.38% 16.19% 14.28% 17.14% Institutional Ownership 62.16% 37.84% 11.93% 25.67% 18.01% Professor’s Privilege 64.94% 35.06% 18.18% 13.00% 20.78% Institutional Ownership 79.29% 20.71% 2.27% 14.56% 9.38% Professor’s Privilege 75.00% 25.00% 10.71% 17.85% 7.15% University patents (n=521) PRO patents (n=337) Multiple answers on type of use were possible. * External use = sale or license or spin-off. Federico Munari – University of Bologna 17 Regression results: main findings • We estimate multivariate probit regression models in order to control for the influence of other factors which might impact on patent commercialization. • The results of regression analyses on the whole sample of university/PRO patents confirm that patents owned by universities are more likely to be licensed. • However, once controlling for other factors, PRO owned patents are less likely to be exploited through direct sale or spin-off formation. • Institutional ownership regime has only a negative and significant effect on the probability of selling the patent Federico Munari – University of Bologna 18 Regression results: main findings • The number of scientific articles at the basis of the patent is positively associated to licensing or spin-off formation. • The existence of an incentive system based on ad hoc payments is positively associated to all types of commercialization. • The funding sources exploited for the patented invention have a significant impact: the use of funding from external sources (external firms, customers, suppliers) and the receipt of VC funding are associated to a higher likelihood of sale of spin-off formation. Federico Munari – University of Bologna 19 Policy implications • Our analyses suggest that the share of university owned patents (as compared to university invented patents) has significantly increased over the last decade. The reforms towards institutional ownership regimes seem to had an impact in this respect. • A large share of university and PRO patents still remain commercially unexploited. Need to understand in more depth the barriers to commercialization. • In our data, PRO patents tend to have significantly different commercialization rates as compared to university patents. Further evidence is needed on this point. Most of the attention of academic research has been devoted to universities, less to PROs. • Further analyses (not reported here) show that US patents in our sample tend to have significantly higher licensing rates than European patents (differences in terms of sale and spin-off formation are less pronounced), suggesting the existence of a gap in this respect. Federico Munari – University of Bologna 20 Policy implications • We provide evidence-based support for a positive impact of university ownership on licensing, less for the other two forms of commercialization. • Our results thus suggest the need to disentangle the different forms of exploitation. • Our results suggest that inventions more intensively rooted in science tend to have higher commercialization outcomes. Need to strengthen the university/PRO position in science in order to promote technology transfer. • The financial sources adopted to generate the patented invention do affect commercialization results. Importance of implementing adequate financial instruments to support technology transfer and address the existence of funding gaps. Federico Munari – University of Bologna 21 The FinKT project: objectives • Overall goal: to map and analyse the financial instruments and the forms of partnerships between financial investors and universities/PROs that can facilitate technology transfer in Europe • The project is undertaken by the Department of Management of the University of Bologna, in collaboration with Bocconi University (Duration: Mar 2012-Feb 2015) • The project is funded by the European Investment Bank, under the EIBURS measure • Project website: finkt.unibo.it Federico Munari – University of Bologna 22 Contacts and project website Project website: finkt.unibo.it Federico Munari, federico.munari@unibo.it Federico Munari – University of Bologna 23