MODULE 6 1. Fajans titration uses _______ indicator. A. Acid-base B. Adsorption C. Metal- ion D. NOTA 2. Other name of ferric ammonium sulphate A. B. C. D. Ferric alum Fe NH4 (SO4)2 Fe (NH4)2 (SO4)2 A and B 3. These are straight filaments arising from the bacterial cell wall, making the bacterium look like porcupine. A. B. C. D. Capsule Endospores Fimbriae Flagella 4. Standard solutions are also known as: A. B. C. D. Test solutions Volumetric solutions Saturated solutions NOTA 5. The end point in using ferric ammonium sulphate is: A. B. C. D. White precipitate Red-brown color Pink color Blue color 6. A structural component of the cell that may enhance virulence of the bacterium include A. B. C. D. Capsule Hyalauronidase Flagella Lecitinase 7. Indicator in the Iodometric method of analysis: A. B. C. D. KMnO4 Methyl red TS Methyl orange TS Starch TS 8. Assay of diluted HCl is expressed in: A. B. C. D. %w/w %w/v Both A and B NOTA 9. The source of H antigen A. B. C. D. Flagella Cell wall Pilus Plasmid 10. Residue on Ignition is also called: A. B. C. D. Loss on Ignition Loss on Drying Acid-insoluble ash Sulfated ash 11. Limit of moisture in non-aqueous titrimetric analysis is less than: A. B. C. D. 0.5 % 0.05% 0.2% 0.02% 12. A vaccine antigen that primarily induces opsonizing antibody is A. B. C. D. Hepatitis B virus vaccine MMR vaccine Rabies vaccine H. influenzae type b vaccine 13. Method II of determining Iodine value is also known as: A. B. C. D. Hubl’s method Wij’s method Hanus method AOTA 14. Standard Operating Procedure (SOP): A. Concerned with record keeping B. Done to facilitate recall C. Step by step method on how to go about a job D. AOTA 17. The maximal reaction time for tuberculin reaction A. B. C. D. 2-5 hours 6-10 hours 12-20 hours 48-72 hours 16. To determine the total ash, the sample is incinerated at a temperature of 675 + 25°C. This temperature is represented by: A. B. C. D. Very dull red heat Dull red heat White red heat Bright red heat Very dull red heat 500-550°C Dull red heat 550-700°C Bright red heat 800-1000°C Yellow red heat 1000-1200°C White red heat 1200-1600°C 17. A critical defect that would stop the packaging line operation: A. B. C. D. Wrong labels Inverted labels Misaligned labels Smeared 18. Streptomycin is known for A. B. C. D. Erythema nododum leprosum Bone marrow depression Discoloration of the teeth Vestibular damage 19. Hydrolysis products of ASA: A. B. C. D. Acetic acid + sodium hydroxide Acetic acid + salicylic acid Salicylic acid + sodium hydroxide Sodium salicylate + water C6H4OCOCH3COOH + H2O C6H4OHCOOH + CH3COOH 20. Pyrogen test in vitro: A. B. C. D. Colorimeter Fluorophotometer Cylinder-plate method LAL method 21. A spinal fluid specimen from a 28 year old man shows N. meningitides. The DOC is A. Pen G B. Amikacin C. Kanamycin D. Ethambutol 22. The type of glass most suitable for parenteral preparation is: A. B. C. D. Type I Type II Type III NP 23. A firm’s removal or correction of a distributed product which involves no violation A. B. C. D. Drug recall Stock recovery Market withdrawal NOTA 24. Tetracycline may be the DOC for all except: A. B. C. D. LGV Inclusion conjunctivitis Hospital acquired PNX due to klebsiella Psittacosis 25. A small volume intravenous solution has a maximum volume of: A. B. C. D. 1000 ml 200 ml 500 ml NOTA 26. A dye used in the leaker test: A. B. C. D. Methylene blue Phenolphthalein Thymol blue NOTA 27. Sulfamic acid (H3NSO3) is a primary standard that can be used to standardize sodium hydroxide. What is the molarity if 34.26mL reacts with 0.3337g of sulfamic acid MW=97 A. B. C. D. 0.304 0.1004 0.1005 0.403 28. The human papilloma virus is the causative agent of: A. B. C. D. Measles Chancre Warts Herpes 29. Bleeding is a main stability problem seen in: A. B. C. D. Capsules Ointments Emulsions Tablets 30. This expensive drug is given for dapsone-resistancy M.leprae A. B. C. D. Thalidomide Para-aminosalicylic acid Clofazime Rifampicin 31. A spinal fluid specimen from a 28 year old man shows N. meningitides. The DOC is A. Pen G B. Amikacin C. Kanamycin D. Ethambutol 32. A sterilizing filter has a pore size of A. B. C. D. 0.5 µm 0.2 µm 1 µm NOTA 33. This is an antifungal that acts as by inhibiting lansosterol C14- demethylase, an important enzyme in sterol synthesis A. B. C. D. Griseofulvin Miconazole Flucytosine Ampothericin 34. The human papilloma virus is the causative agent of: A. B. C. D. Measles Chancre Warts Herpes 35. Clean room classifications are specified in Federal Standard A. B. C. D. 211E 210E 209E NOTA 36. Use to prevent one element from interfering in the analysis of another element A. B. C. D. Masking agent Demasking agent Both a and b NOTA 37. A type of relationship in which one species of organism uses the body of a larger species as its physical environment and makes use of that environment to acquire nutrients. A. Commensalism B. Mutualism C. Parasitism D. Symbiosis 38. The Philippines belongs to what climactic zone: A. B. C. D. I II III IV 39. Describe how close a measure value is to the true value A. B. C. D. Accuracy Precision Range Standard deviation 40. The minimum time period covered by the data for accelerated stability studies is: A. 6 months B. 12 months C. 18 months D. NOTA 41. Disintegration is an essential attribute of this dosage form: A. B. C. D. Plain coated tablet Hard gelatin capsule Chewable tablet AOTA 42. Tetanus, botulism, diphtheria A. B. C. D. E. Immediate hypersensitivity Cytotoxic antibody Immune complex Delayed hypersensitivity NOTA 43. Which is not a biological indicator in the validation of a moist heat sterilizer? A. B. C. D. Bacillus stearothermophilus Bacillus subtilis Bacillus coagulans NOTA 44. The acceptable pH level of water used for pharmaceutical compounding is A. B. C. D. Between 6.0 and 7.0 Between 5.0 and 7.0 Between 7.0 and 8.0 NOTA 45. Treatment of herpectic conjunctivitis A. B. C. D. Streptomycin Iododeoxyuridine Rifampicin Nalidixic acid 46. This is given together with Isoniazid for patients with TB to prevent neurologic side effects: A. B. C. D. Rifampicin Ethambutol Pyridoxine Pyrazinamide 47. The type of glass most suitable for parenteral preparations is A. B. C. D. Type I Type II Type III NP 48. What is the titer value 0.05M calcium chloride with 2 moles of water? MW=142.9 A. B. C. D. • 3.57mg 7.15mg 73.5mg 53.7mg 49. This is the smallest tapeworm that infects humans: A. B. C. D. Taenia solium Taenia saginata Hymenolepsis nana Echinococcus granulosus 50. Safety and Toxicity tests are conducted using: A. B. C. D. Rabbits Dogs White mice Guinea pig 51. The process in which the exact concentration of solution is determined A. B. C. D. Neutralization Standardization Titration Complexation 52. This is also known as the Giant intestinal fluke: A. B. C. D. Fasciola hepatica Clonorchis sinensis Fasciolopsis buski Schistosoma japonicum 53. A spectrophotometer differs from a colorimeter is that it is consists of: A. B. C. D. Prism Lamp house Cell compartment B and C 54. The crude fiber of a drug usually consist of: A. B. C. D. Cellulose Cholesterol Phytosterol Lard 55. This is the diagnostic test for the presence of Enterobius vermicularis: A. B. C. D. Kato thick method Kato-katz method Scotch tape swab method Brine flotation technique 56. The primary staining reagent of the gram procedure is: A. B. C. D. Methyl red Carbol fuchsin Crystal violet Saffranin 57. Twenty tablets of ascorbic acid weighed 4.250g and a powdered sample of 0.3075g used up 21.5mL of 0.1085N iodine solution. What was the amount of Ascorbic acid per dose of 2 tablets? Each mL of 0.1N iodine is equivalent to 8.80mg of C6H6O6 (Ascorbic acid). The amount is: A. 283.7mg B. 141.86mg C. 0.2837g D. A & C 58. This is the form of malarial parasite that is taken up by the mosquito as it bites on humans: A. B. C. D. Gametocytes are the cells taken by a biting anopheles Sporozoites mosquito from man. The Merozoites male and female Trophozoites gametocyte will fuse in the Gametocytes mosquito’s stomach into an Oocyst that will give rise to the sporozoites. 59. Adsorption indicators are used in: A. B. C. D. Complexation reaction Acidimetry Volumetric precipitation Alkalimetry 60. Iodimetry is what type of titration A. B. C. D. Direct Indirect Residual A&C 61. This is the malarial species that causes the so called “Quartan Malaria” A. B. C. D. P. ovale P. vivax P. malariae P. falciparum P. malariae produces fever every 72 hours or three days which is the so called Quartan malaria, P. Vivax and P. ovale produces fever every 48 hours hence called the Tertian malaria, P. falciparum produces fever every 36-48 hours which is also known as Malignant tertian malaria. 62. To measure the optical activity of a sample, the instrument used is: A. B. C. D. Polarimeter Refractometer Spectrometer Flame photometer 63. The type of alkaloidal assay where the total alkaloids are determine is: A. B. C. D. Ultimate Specific Proximate Precision 64. This is the ingested infective form of protozoan parasites in humans: A. B. C. D. Cysts Merozoites Trophozoites Cytostomes Trophozoites are the motile form (juvenile), Cytostome is the mouth from which pieces of food is ingested. 65. The unsaponifiable matter present in animal fats is: A. B. C. D. Cholesterol Phytosterol Lard Wax 66. The infrared region of the spectrometer used to identify a substance uses a wavelength range of: A. B. C. D. 3-15μm 380-780μm 200-380μm 15-300μm 67. This organism causes a non-bloody diarrhea: A. B. C. D. Entamoeba histolytica Giardia lamblia Isospora belli Strongyloides stercolaris 68. What is the other name of Koettsdorfer number? A. B. C. D. Acid value Saponification value Ester value Iodine value 69. Using a spectrophotometer to measure the concentration of a sample, the following data were obtained absorbance (A) of the standard solution was 0.55 A of the sample was 0.58 The concentration of the standard used was 16.5mcg The concentration of the sample was: A. 15.5mcg B. 17.55mcg C. 17.40mcg D. 15.9mcg 70. Koplik’s spots seen among patients with measles are usually localized in the: A. B. C. D. Upper extremities Lower extremities Mouth Scalp 71. Body louse is the vector for A. B. C. D. Leptospirosis Pinta Epidemic relapsing fever Meningitis 73. Aside from Praziquatel, this is also given for tapeworm A. B. C. D. Diethylcarbamazine Ivermectin Mebendazole Niclosamide 73. A defect that may affect the function of an object and therefore, may render the product useless A. B. C. D. Major defect Minor defect Critical defect Ocular defect 74. Given a tablet thickness of 0.47cm, what should be the acceptable tablet range? A. B. C. D. 0.4465-0.4935cm 0.4230-0.5170cm 0.4348-0.5050cm 0.3225-0.5875cm 75. The oxidation number of Mn in KMnO4 A. B. C. D. +2 +1 +5 +7 76. If a sample of white wax is found to have an ester value of 65.7 and a saponification value 74.2, what is the acid value of the sample? A. B. C. D. 8.5 86.5 186.5 56.5 77. Also known as Eosin Y A. B. C. D. Dichlorofluorescein Tetrabromophenolpthalein Tetrabromofluorescein Xylenol Orange 78. Calculate the weight of oxalic acid required to prepare 1000mL of 0.5N of the solution. MW=126 A. B. C. D. 36.5g 63.5g 31.5g 23.5g 79. Determine the iodine value of an unknown sample of oil weighed 0.21g if 26mL and 12mLof 0.1100N of sodium thiosulfate are required for the blank and residual titration respectively A. 90 B. 93 C. 108 D. 200 80. Titer is an expression of concentration in terms of: A. B. C. D. Grams of solute per 100mL Grams or mg of solute per mL Grams per liter A&C 81. The molecular weight of sulfuric acid is 98. Its equivalent weight is: A. B. C. D. 98 49 0.098 0.049 82. The oil from peppermint spirit can be determined by using: A. B. C. D. Cassia flask Bobcock bottle Pycnometer Titration 83. Which of the following is an example of aerobic organism? A. B. C. D. Listeria monocytogenes Chlamydia trachomatis Staphylococcus aureus Mycoplasma pneumonia 84. This spirochete is tightly coiled, thin, and has a hook at its end A. B. C. D. • Vibrio Borrelia Leptospira Treponema 85. A 4-year old kid complains of itchiness in his anal area. Anal swab from this patient will reveal larvae of which of the following? • • • • Leptospira interogans Chlamydia trachomatis Helicobacter pylori Enterobius vermicularis 86. This species of Shigella is responsible for the most infection on the milder side of the spectrum of Shigellosis. A. S. dysenteriae B. S. sonnei C. S. boydii D. S. flexneri 87. Beer’s plot in spectrophotometry is prepared to determine: A. B. C. D. Absorbance of the sample Wavelength to be used Blank Concentration of the drug substance 88. One of the following is NOT an in process for tablet A. B. C. D. Bioavailability Weight variation Hardness and thickness Disintegration 89. The temperature used for ignition to constant weight is: A. 725 + 25˚C B. 825 + 25˚C C. 800 + 25˚C D. 750 + 25˚C 90. Potency of a 100mg tablet at expiry date A. B. C. D. 95mg 105mg 90mg 110mg 91. The ester value determination of substance is applicable to the following, EXCEPT: A. B. C. D. Fats Volatile oils Alcohol Fatty oil 92. To keep samples moisture free the apparatus used is: A. B. C. D. Dessicator Furnace Incubator Oven 93. The indicator for EDTA titration against CaCO3 is: A. B. C. D. • Thymol blue Hydroxynaphthol blue Methyl red Methylene blue 94. Adsorption indicators are used in: A. B. C. D. Complexation reaction Acidimetry Volumetric precipitation Alkalimetry 95. Analysis where separation of the constituents from the sample is done by weighing the product is: A. B. C. D. Volumetric Gravimetric Special Gasometric method 96. The primary staining reagent of the Gram procedure is: A. B. C. D. Methyl red Carbol fuchsin Crystal violet Saffranin 97. Which organism is suspected to have infected a goat farmer who had complained a fever of unknown cause? A. B. C. D. Brucella militensis Brucella abortus Brucella suis Bacillus cereus 98. Diphyllobotrium latum infection may lead to the deficiency of which vitamin? A. B. C. D. Vit A Vit B6 Vit B1 Vit B12 99. All are extracellular parasite, except; A. B. C. D. Enterobius Trichinella Strongyoloides Ascaris 100. This sexually transmitted protozoan is common among male homosexual A. B. C. D. Giardia lamblia Entamoeba histolytica Faciola hepatica Ascaris lumbricoides