DIMET OPEN DAYS
MONDAY, SEPTEMBER 22nd, 2014
UNIVERSITY’ OF MILANO-BICOCCA, VILLA DI BREME FORNO, Building U46, Via Martinelli 23, Cinisello Balsamo (MI)
09.30 – 9.45: Introduction – Andrea
Biondi/Sergio Ottolenghi
ORAL PRESENTAIONS
10.30-10.45: “Antitumor activity of Laspariginase in a preclinical model of mature
T-cell non Hodgkin Lymphoma” Giuseppe
GRITTI- Tutor: Martino Introna (AO Papa
Giovanni XXIII, BG)
Oncology and Hematology
09.45-10.00:
“Role
of
the
human
hematopoietic niche in inducing and
supporting Myelodysplastic Syndrome
and/or leukemia evolution in ShwachmanDiamond Syndrome patients” Bardelli
DONATELLA – Tutor: Andrea Biondi
(UNIMIB), Co-Tutor Giovanna D’Amico
(Fondazione M. Tettamanti)
10.45-11.00: “BAFF Receptor is a potential
target for the CAR-mediated treatment of
B-cell Acute Lymphoblastic Leukemia (BALL)” Nice TURAZZI - Tutor: Ettore Biagi
(UNIMIB)
10.15-10.30: “Emergence of a CXCL13+
stromal cell niche during B-cell chronic
lymphocytic leukemia development involves
activation of Retinoic Acid Pathway” Diego
FARINELLO - Tutor:
Silvia Brunelli
(UNIMIB), Co-Tutor: Andrea Brendolan
(HSR)
ORAL PRESENTAIONS
Pulmonary
POSTER SESSION
1. “Characterization of transcriptional targets and
signal transduction pathways downstream to Sox6 in
human hematopoietic cell lines” Gloria BARBARANI Tutor: Antonella Ronchi (UNIMIB)
11.30-14.15: POSTER SESSION
Cardiovascular,
Diseases
15.45-16.00: “Role of RAGE in cardiac aging” Filippo
ZENI – Tutor: Giulio Pompilio (Centro Cardiologico
Monzino)
Cellular and Molecular Mechanisms
11-11.30: Coffee Break
14.15: Lunch
10.00-10.15: : “Redox homeostasis in the
multiple
myeloma
niche”
Stefano
BESTETTI - Tutor:
Andrea Biondi
(UNIMIB), Co-Tutor: Roberto Sitia (HSR)
15.30-15.45: “Heteromeric Nicotinic Receptors in brain
development and implications for sleep-related
epilepsy” Simone BRUSCO Tutor: Andrea Becchetti
(UNIMIB)
and
Neural
15.00-15.15: “Gene-modifiers in the LQT1
syndrome: mechanistic analysis of NOS1-AP
polymorphism” Joyce BERNARDI - Tutor:
Antonio Zaza (UNIMIB)
15.15-15.30: “Relevance of electrolytic
balance in channelopathies” Anna BINDA –
Tutor: Ilaria Rivolta (UNIMIB)
2. “Next-generation sequencing analysis of miRNA
expression in control and FSHD myogenesis” Veronica
COLANGELO - Tutor: Raffaella Meneveri (UNIMIB)
3. “Genetic correction of endogenous mutations and
reprogramming of patient-derived cells to develop new
strategies for hematopoietic cell gene therapy” Claudia
FIRRITO- Tutor: Giuliana Ferrari/Luigi Naldini (HSR)
DIMET OPEN DAYS
MONDAY, SEPTEMBER 22nd, 2014
UNIVERSITY’ OF MILANO-BICOCCA, VILLA DI BREME FORNO, Building U46, Via Martinelli 23, Cinisello Balsamo (MI)
4. “Role of MYC in the regulation of stem
cell features in human mammary epithelial
cells through activation of the WNT
pathway” Vittoria POLI – Tutor: Alessio
Zippo (INGM)
9. “TGFb signaling pathway impairment is
involved in the reversion of chemioresistance
of colon cancer cells in in vivo and in vitro
models” Gabriele ROMANO – Tutor: Roberto
Giovannoni (UNIMIB)
5. “Characterization of two different
protein isoforms of SMARCA2 gene”
Aurora RIGAMONTI - Tutor: Silvia
Barabino (UNIMIB)
Cardiovascular, cerebral and neuromuscular
pathology
Oncology and Immunology
6. “Targeting the CD123 antigen in
pediatric Acute Myeloid Leukaemia with a
spectrum of Chimeric Antigen Receptors
affinity mutants for the evaluation of the
ideal CAR in cancer treatment ” Silvia
ARCANGELI – Tutor: Ettore Biagi
(UNIMIB)
7. “Modulation of CD8+ T Cell Responses
by HLA-G-expressing DC-10” Michela
COMI - Tutor: Francesca Granucci
(UNIMIB), Co-Tutor: Silvia Gregori (HSR)
8. “Chemotherapy and radiotherapy impact
on glioblastoma immunogenicity” Sara
PESSINA - Tutor: Gaetano Finocchiaro
(Istituto Neurologico C. Besta), Co-Tutor:
Serena Pellegatta (Istituto Neurologico C.
Besta)
10. “Expression of complement and ischemic
tolerance biomarkers in patients with
aneurysmal
subarachnoid
haemorrhage.”
Maria Giulia ABATE – Tutor: Antonio Pesenti
(UNIMIB)
11. “Molecular Hallmarks in Myasthenia
gravis” Claudia BARZAGO - Tutor: Renato
Mantegazza (Istituto Neurologico C. Besta)
(SIgN/A*STAR, Singapore)
14. “Cardiac specific ablation of Palladin induces systolic
disfunction” Giuseppina MASTROTOTARO – Tutor:
Marialuisa Lavitrano (UNIMIB), Co-Tutor: Gianluigi
Condorelli (UNIMI)
15. “Cholinergic transmission in the cerebral cortex of a
murine model of ADNFLE.” Simone MENEGHINI –
Tutor: Andrea Becchetti (UNIMIB)
16. “The Hurler syndrome: a better understanding of
skeletal development through the use of patientspecific induced pluripotent stem cells (iPSCs)” Anna
MONTAGNA - Tutor: Marta Serafini (Telethon)
17. “Characterisation of TTC19 knockout mouse, a model
of mitochondrial encephalopathy disease” Emanuela
BOTTANI – Tutor: Massimo Zeviani, (Istituto
Neurologico C. Besta)
12. “Role of HMGB1 redox state on cardiac
fibroblasts function” Stefania DI MAGGIO –
Tutor: Giulio Pompilio, Co-Tutor:
Angela
Raucci (Centro Card. Monzino)
18. “Mutations of C19orf12, coding for a novel
mitochondrial protein responsible for NBIA syndrome,
cause mis-localization of the protein and insensitivity to
oxidative stress” Paola VENCO - Tutor: Valeria Tiranti
(Istituto Neurologico C. Besta)
13. “Characterisation of muscle fibrosis in a
mouse model and In Vivo Test of anti-fibrotic
molecules” Sara GIBERTINI – Tutor: Renato
Mantegazza, (Istituto Neurologico C. Besta)
19. “Functional characterization of a longevityassociated BPIFB4 variant improving endothelial
function” Francesco VILLA – Tutor: Silvia Brunelli
(UNIMIB), Co-Tutor: Annibale Puca (CNR)