Gabby Badurek and Stef Amedrano
Period 6/7
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Albinism is a disorder that affects the skin, hair, and eyes.
The hair, eyes, and skin usually have no pigment(color).
Symptoms:
• No color in hair, skin, or iris of the eyes.
• Lighter hair color and skin.
• Patch, or missing skin color.
Interesting Facts:
• Sometimes the eye color can change
• People with albinism are sensitive to light (photophobic)
• Other forms of Albinism are involved with symptoms of other disease
 OCA1
is located in Chromosome 11
.
Chromosome 11
Location of OCA1 on Chromosome 11
Albinism
is Autosomal Recessive
Autosomal Recessive- Two copies of the abnormal
gene must be present in order for the disease or
trait to develop.
 Allele-
Alternative forms of a gene for each variation of a trait of an
organism.
 One from mother, One from Father.
 Recessive- aa
-Trait that can be masked by the dominant form of a trait.
 Dominant- AA
• Observed trait that masks the recessive form of a trait.
 Carrier- Aa
• Trait that has both a good gene and bad gene, but doesn’t have the bad
gene effect.
A
a
A AA
Aa
Aa
aa
a
a
A
A
a
Aa
Aa
Aa
Aa
A
a
AA
A
Aa
Aa
aa
a
Ratios1 2 1
AA | Aa | aa
Percentages25% 50% 25%
AA | Aa | aa
A AA
a
Aa
A
Aa
a
aa
Phenotype:
AA= Not albino
Aa = Not Albino but Gene Carrier
aa= No Melanin/Albino
A = Dominant Allele
a = Recessive Allele
Genotype: In Gene
AA = Homozygous
Dominant(not albino)
Aa = Heterozygous dominant(not
albino)
aa = Homozygous recessive(albino)
A
A AA
Aa
Aa
aa
a
a
Genotype- Genes (Genetic)
Ratios:
1AA : 2Aa : 1aa
Percentages:
25%AA: 50%Aa: 25%aa
Phenotype- Physical (Seen)
Ratios:
1 Albino ; 3 Not Albino
Percentages:
25% Albino ; 75% Not Albino
a Aa
Aa
a
A
aa
aa
a
Genotype:
Ratio:
Percentage:
Phenotype:
Ratio:
1:1:2
AA : Aa : aa
25% : 25% : 50%
AA : Aa : aa
2 NO Albinism; 2 Albinism
Percentage:
50% No Albinism; 50% Albinism
Gabby
Ventura
Jeff
Jessica
Emma
Tyler
Steph
Yvenson
Purple- Fine. NO ALBINISM!
Pink- Not fine. ALBINISM PRESENT!
Rectangle- Male
Oval- Female
Kevin
Stef
Key
Circle: Female
Square: Male
Pink: Albinism
Purple: Non-Albinism
Ventura
Jeff
Gabby
Jessica
Emma
Tyler
Steph
Yvenson
Questions:
1. What will happen to the child if both of the parents have recessive
genes?
2. What would 2 results be if Emma(aa) and a male carrier(Aa) had
children?
3. Would the child have a possibility of albinism or not?
Kevin
Stef
THE END 