NIH Institutional Training Programs: Preparing a Successful T32 Application Alison K. Hall, Ph.D. Deputy Director Division of Training, Workforce Development and Diversity National Institute of General Medical Sciences National Institutes of Health June 28, 2013 PhD Training Continues to Evolve NIH has supported research training since 1930s fellowships thru the 1950s National Research Service Award 1975 (i.e. T32, F30/31, F32; MARC) Ruth L. Kirschstein -funding to scientists, not health professionals -to enhance research training -in scientific areas with need for researchers -good curricula, facilities, program in add’n to research -dedication to developing talent 2 NIH Regional Seminar June 28, 2013 PhD support is largely on research grants Consider differences in apprenticeship vs a program Source: Graduate Student Survey, NSF 3 Training In light of Multiple Career Outcomes Employment of Biomedical Science PhDs by Sector Number 140,000 120,000 Other Government 100,000 Industrial All Academic 80,000 60,000 40,000 20,000 - 1973 1977 1981 1985 1989 1991 1993 1993 1995 1997 1999 2001 2003 2006 2008 NEW Source: http://sestat.nsf.gov/ 4 Training in light of limited diversity in workforce Biomedical Workforce US Population 100% 100% 90% 90% 80% 80% 70% 70% 60% 60% 50% 50% 40% 40% 30% 30% 20% 20% 10% 10% 0% 0% 2008 2050 Source: US Census; NSF, 2007 5 Temp. Res. non-URM URM Snapshot of the PhD Biomedical Workforce http://acd.od.nih.gov/Biomedical_research_wgreport.pdf NOTE: The color of College Graduates the numbers reflects the confidence in the accuracy of the data. 16,000 in 2009 Graduate Education & Training Of graduates who stay in the US 4,000 in 2009 2009 Total: 83,000 Time to Degree :5.5-7yrs 2009 Graduates: 9,000 skip a postdoc 8% of International graduates leave the US 5,800 in 2009 Postdoctoral Training do a postdoc 2009 Total: 37,000 to 1,900 to 3,900 68,000 in 2009 Median Length: 4 years Post-Training Workforce Science Related NonResearch 6 Governmen t Research 18% 6% Biomedical US- trained PhD 2008 Biomedical US- trained PhD 2008 ~24,000 ~7,000 Academic Research or Teaching 43% (23% tenured) Biomedical US- trained PhD 2008 ~55,000 Industrial Research Total of ~150,000 Biomedical US-trained (128,000 Biomedical US-trained PhDs)PhD’s NonUnemployed Science Related 18% 13% 2% Biomedical US- trained PhD 2008 Biomedical US- trained PhD 2008 Biomedical US- trained PhD 2008 ~22,500 ~17,000 ~2,500 Institutional Training Programs • Enhance research training through a coordinated programmatic approach • Involve many faculty, multiple departments • Trainees are selected by the institution • Parent Announcement Update T32 FOA updates expected July appl due January 2014 7 Strategies to Develop a Strong Proposal 1. Start Early 2. Consider why a TG is important for your program 3. Be very sure there is a PROGRAM 4. Complete tables before finalizing narrative 5. Review the review criteria 6. Explain, explain, explain. Remember reviewers are expert faculty familiar with training 8 Institutional Training Review Criteria ~750 Electronic TG Submissions (May; Sept, Jan) Center for Scientific Review to Institute/Center Study Section—Initial Review Group 3-4 reviewers Established scientists, many with training experience Program merit Scored Review Criteria: 1. Training Program and Environment 2. Training Program Director/Principal Investigator 3. Preceptors/Mentors 4. Trainees 5. Training Record Overall Impact Score: 1-9 Institute or Center Council Program relevance, guidance to program staff 9 Hallmarks of Good Training Programs Student development for biomedical team experience, contributions, growth, project Contemporary, mentored research education broad and deep academic curriculum research skills and knowledge conceptual judgment, right questions communication skills Career development for multiple outcomes as a scientist (fellowships, mtgs, papers) teaching activity? Leadership? Mgmt? externships? Policy? Workshops? Responsible Conduct 10 Training Programs are Developmental, not Selection Potential Trainees How select for TG and why Matriculant UG major Research Interest Courses taken Lab affiliation PhD Program Pilot research 11 Program Activities Planned interventions Milestone/ Outcomes Intended changes Mentored Research PI, advisory comm research design new techniques Planned Curriculum knowledge teaching Skill building oral communication writing workshops new collaborations Contemporary science meet new scientists Career Exposure know next steps Short term Research publications Poster, meeting Fellowship Longer term Next position Biomedical career Research grants Mentoring others Active Program Beyond Research in PI lab “value added” PROGRAM IS MORE THAN WORK IN A LAB Active nomination, selection of candidates from pool Planned academics with flexibility Seminars, enhancement activities Longitudinal program beyond funding Faculty trainer responsibilities make program strong Intentional activities to achieve outcomes 12 1. Training Program and Environment • Are the research facilities and training environment conducive to prepare trainees for successful careers as biomedical scientists? • Do the objectives, design and direction of the proposed research program ensure effective training? • Is the proposed program of training likely to ensure that trainees will be prepared for successful and productive scientific careers? • Do the courses, where relevant, and research training experiences address state-of-the-art science relevant to the aims of the program? • Does the program provide training in inter- or multidisciplinary research and/or provide training in state-ofthe-art or novel methodologies and techniques? • Is a significant level of institutional commitment to the program evident? 13 2. Training Program Director/Principal Investigator Does the Training PD/PI have the scientific background, expertise, and experience to provide strong leadership, direction, management, and administration to the program? His/her trainees, outcomes Does the PD/PI plan to commit sufficient time to the program to ensure its success? Is sufficient administrative and research training support provided for the program? Is a strong justification provided that the multiple PD/PI leadership approach will benefit the training program and the trainees? roles and responsibilities, governance, and organizational structure consistent with and justified by training program and with the complementary expertise of PD/PIs? 14 3. Preceptors/Mentors Are sufficient numbers of experienced preceptors/mentors with appropriate expertise and funding available to support the number and level of trainees proposed in the application? 3-4x faculty available to student, not all one lab… Do the preceptors/mentors have strong records as researchers, including successful competition for research support in areas directly related to the proposed research training program? How diverse are faculty? Do the preceptors/mentors have strong records of training preand/or postdoctorates? 15 4. Trainees Is a recruitment plan proposed with strategies to attract high quality, diverse, trainees? Are there well-defined and justified selection criteria and retention strategies? Nomination, re-appointment criteria, process Is there evidence of a competitive applicant pool in sufficient numbers to warrant the proposed size and levels? TG is catalytic, supports a third(?) of relevant TGE students 16 4. Trainees (cont) For renewal applications, how successful has program been in attracting and retaining individuals from diverse populations, including populations underrepresented in science? Report Trainees Training Grant Eligible Students from groups underrepresented in biomedical science Students with disabilities, defined as physical or mental impairment that substantially limits one or more major life activities. 17 Once in program, students change minds …and make choices about careers Graduate students in basic biomedical sciences • Many initially have goal of academic research • Midway thru PhD are considering multiple careers What does the change in attitude mean? didn’t know possibilities when began grad school perhaps worried about academic path learned more about what’s enjoyable identified next steps for careers Fuhrmann et al 2011 CBE Life Sci Educn 10: 239-249 18 How Assess Skills and Interests? Individual Development Plan To be used in training, fellowships, RPGs… 19 The IDP involves The scholar The mentor self assessment Survey opportunities Write IDP Implement plan familiarity with opportunities discuss opportunities review IDP, help revise assess new tasks, progress in light of the plan 1.Skills assessment-strengths and weaknesses 2.Career match- do goals match skills and interest 3.Do it again next year 20 5. Training Record How successful are the trainees in completing the program? How productive are trainees in terms of research accomplishments and publications? How successful are trainees in obtaining further training appointments, fellowships, and/or career development awards? How successful are the trainees in achieving productive scientific careers, as evidenced by successful competition for research grants, receipt of honors or awards, high-impact publications, receipt of patents, promotion to scientific leadership positions, and/or other such measures of success? 21 5. Training Record For programs that provide research training to healthprofessional doctorates, is there a record of retaining health professionals in research training or other research activities for at least two years? Does the program have a rigorous evaluation plan to assess the quality and effectiveness of the training? Annually assess outcomes? Adapt to changes? Test intervention hypothesis? Are effective mechanisms in place for obtaining feedback from current and former trainees and monitoring trainees’ subsequent career development? 22 Institutional Training Additional Review Criteria & Considerations Additional Review Criteria Protection for Human Subjects Inclusion of Women, Minorities, and Children Vertebrate Animals Biohazards Resubmission, Renewal, Revision factors Additional Review Considerations: Diversity Recruitment Plan Training in Responsible Conduct of Research Select Agent Research Budget and Period of Support 23 Table 1. Participating Departments (Finish this table last…complicated) Table 1. Membership of Participating Departments/Programs (Alphabetically) For Renewal For Renewal Applications, Postdoctoral Applications, Predoctoral Trainees in Postdoctoral Postdoctoral Trainees Department / Trainees Trainees Supported by Program With Supported by This Training (Supported Participating This Training Grant Grant by Any NIH Faculty (TGE) Training (TGE) (TGE) A/B/C Grant) A/B/C A/B/C Faculty Members in Department / Program Faculty Members Participating in This Application Predoctoral Trainees in Department / Program (Supported by Any NIH Training Grant) Dept. of Biology 45 14 38 (15) 12 (6) 1/1/0 2 (2) 1/0/0 50 (5) 15 (7) 1/0/0 2 (2) 0/0/0 Neuroscience Program 32 20 31 (20) 14 (7) 2/0/1 4 (4) 0/1/0 40 (7) 23 (10) 0/0/1 2(2) 1/0/0 Dept. of Pharmacology (Medical School) 25 5 30 (10) 5 (3) 1/0/0 3 (3) 0/0/0 28 (0) 12 (6) 0/0/1 0 (0) 0/0/0 Totals N/A N/A 99 (45) 31 (16) 4/1/1 9 (9) 1/1/0 108 (12) 50 (23) 4 (4) 1/0/0 Participating Department / Program Predoctoral Trainees With Participating Faculty (TGE) A/B/C Table 1 Instructions: Provide the total number of current faculty members, predoctoral trainees, and postdoctoral trainees in each participating department/program. Indicate the number of faculty members participating in this training grant application, the numbers of predoctoral and postdoctoral trainees with the participating faculty, and in parenthesis put the number of these trainees who are training grant eligible (TGE). For renewal applications, include the number of trainees currently supported by the training grant. Faculty members may count as part of both their primary department and an interdepartmental program(s). Predoctoral and postdoctoral trainees count only once and should be associated with a single department or program. underrepresented minorities (Group A), who are individuals with disabilities (Group B), or who are individuals from disadvantaged backgrounds (Group C). Rationale: This table provides insight into the environment in which training will take place. It allows reviewers to assess whether the program has the "critical mass" (trainees, faculty and other research personnel, and representation/distribution of scientific disciplines) to be successful. 24 24 Table 2. Participating Faculty Members (Easy, easy to modify as program shapes up. Start here) Table 2. Participating Faculty Members (Alphabetically by Faculty Member) Name/Degree(s) Rank Primary (& Secondary) Appointment(s) Role in Program Research Interest Abrams-Johnson, Jane, PhD Asst. Prof. Pharmacology; (Biochemistry-Medical School) Mentor Regulation of Synthesis of Biogenic Amines Jones, Lisa S., MD Res. Asst. Prof. Microbiology and Immunology (Neuroscience Program) Mentor Exec Com Protein Structure, Folding, and Immunogenicity Sandoz, J. Miguel, MD, PhD Assoc. Prof. Neuroscience Program Mentor Developmental Genetics in Drosophila Thomas, C. James, III, PhD Prof. & Chr. Biochemistry and Molecular Biophysics Program Director Molecular and Genetic Analysis of RNA Viruses Table 2 Instructions: List each training faculty member with his/her degree(s), academic rank, primary departmental affiliation and secondary appointments, role in the proposed training grant program, and research interests that are relevant to this program. Rationale: This information allows reviewers to assess the distribution of junior versus senior faculty and clinical versus basic scientists participating in the training program, as well as their distribution by department. The data concisely summarize the scientific areas of the training faculty. 25 Table 3. Existing Institutional Training Grants Table 3. Institutional Training Grant Support Available to Participating Faculty Members, Department(s), or Program(s) Title of Training Grant Funding Source Including Identifying Number Active or Pending Project Period Program Director (Department) ShortPredoctoral Postdoctoral Term Trainees Trainees Trainees Total No. of Supported Supported Supported Participating This Year This Year This Year Faculty Names of Overlapping Faculty Bioimmunotherapy Training Grant T32 CA05964-11 06/02-07/07 Baker, A. (Pathology) 12 25 Abelson Brown Fields Johnson Sung Watson Pharmacological Sciences T32 GM04823-01 Pending 10 19 Jones Jenson Watson Genetic Basis of Mental Illness T32 MH02708-07 06/03-07/08 Johnson, A. (Psychiatry) 7 Johnson Watson Totals N/A N/A James, C. (Pharmacology) N/A 4 4 26 4 0 51 N/A Table 3 Instructions: List all current and pending training support available to the participating faculty members, department(s) or programs(s). For each grant, include the title of the training grant; funding source and complete identifying number; status (active or pending) and dates of the entire project period; name of the program director and department; number(s) of training positions (predoctoral, postdoctoral, and short term), number of participating faculty members; and list overlapping participating faculty members, who are also named in this application. Rationale: This table will permit an evaluation of the level of support for training available to each of the participating departments/programs and the extent to which the proposed training grant overlaps with or duplicates available training grant support. It is useful in determining the number of training positions to be awarded. Explain overlapping faculty! 26 Table 4. Grant Support of Faculty Table 4. Grant and Contract Support of the Participating Faculty Members (Alphabetically by Faculty Member) Faculty Member Source of Support, Grant Number and Status Faculty Member Role on Project and Grant Title Project Period Active Current Year Direct Costs Awarded (Total Direct Costs for Awards With Substantial Future Changes) Jones, J. NIH 1 R01 CA76259-01 * PI - Structure and Function of Acetylcholine Receptors 05/09-05/014 * $190,000 Jones, J. NIH 5 K08 AI00091-03 PI - Purification & Identification of Receptors 11/03-11/08 $140,000 Mack, T. American Heart Assoc. PI - Control of Angiogenesis 03/05-03/08 $185,000 Mack, T. NSF PCM 80-12935 (D. Stockton, PD/PI) Co-PI - Cell Culture Center 12/06-12/09 $180,000 Mack, T. NIH 1 P01 CA71802-02 (D. Stockton, PD/PI) Project Leader of Subproject 4: "Genetic Control of Cell Division" 10/05-10/09 $165,000 Smith, J. None Zachary, A. NIH 1 U01 AI-28507-01 * PI – Human Monoclonal Antibodies as a Therapy for Staphyloccal Enterotoxin 07/09-07/14 * $200,000 ($3 million) Table 4 Instructions: For each participating faculty member, list active and pending research grant and contract support from all sources (including Federal, non-Federal, and institutional research grant and contract support) that will provide the context for research training experiences, but excluding research training grants. If none, state "None." Include the source of support and grant number; role of the participating faculty member (PD/PI, co-PD/PI, etc.) in the grant; title, status (use an asterisk (*) to indicate pending sources of support) and dates of the entire project period; and the current year annual direct costs. If the source of support is part of a multiple project grant (for example, a P01), additionally identify the PD/PI of the overall project, and provide the above information for that component of the grant with which the faculty member is associated. For grants with major budget changes in future years such as clinical trials, include the total direct costs of the award in parentheses. Rationale: This table provides evidence of the strength of the research environment, the availability of funds to support research conducted by the trainees, and the appropriateness of the participating faculty members in terms of their active research support. 27 Table 5. Training Record of Faculty 28 Table 5B. Training Record of Faculty 29 Table 6. Publications of Trainees 30 Table 7A. Admissions and Completion Records for Participating Departments and Programs Table 7A. Admissions and Completion Records for the Participating Departments and Programs During the Past Five Years (Predoctoral Applicants) Department / Program 31 Applicants Applicants Applicants Applied Accepted Enrolled Entering (TGE) (TGE) (TGE) Year A A A/B/C Trainees Still in Program (TGE) A/B/C Trainees Trainees Completed Completed Program Program Trainees Earned PhD or Earned Other Left MD/PhD Degree Program (TGE) (TGE) (TGE) A/B/C A/B/C A/B/C Reason for Leaving Program (if training was not completed) Department of Biochemistry 2003 8 (5) 0 6 (4) 0 4 (3) 0/3/1 2 (1) 0/0/0 1 (1) 0/0/0 0 (0) 0/0/0 1 (1) 0/0/0 Changed career interests Department of Biochemistry 2004 9 (7) 1 6 (4) 10 5 (3) 0/0/0 4 (3) 0/0/0 1 (1) 0/0/0 0(0) 0/0/0 0 (0) 0/0/0 Department of Biochemistry 2005 10 (6) 2 8 (5) 1 5 (3) 1/0/0 4 (3) 0/0/0 0 (0) 0/0/0 MS 1 1/0/0 0 (0) 0/0/0 Went to medical school Department of Biochemistry 2006 12 (9) 3 10 (6) 1 8 (5) 1/0/0 6 (4) 0/0/0 0 (0) 0/0/0 0 (0) 0/0/0 2 (1) 0/0/0 1 left for a job in industry; 1 left for reasons unknown Department of Biochemistry 2007 15 (12) 4 10 (8) 2 8 (6) 2/1/0 8 (6) 2/1/0 0 (0) 0/0/0 0 (0) 0/0/0 0 (0) 0/0/0 Interdepartmental Graduate Program in Genetics 2003 125 (9) 5 24 (18) 0 18 (15) 0/0/0 5 (4) 00/0 12 (11) 0/0/0 0 (0) 0/0/0 1 (0) 0/0/0 Transferred to Bioengineering PhD program Interdepartmental Graduate Program in Genetics 2004 123 (91) 3 22 (17 1 16 (16) 1/0/0 10 (10) 0/0/0 4 (4) 0/0/0 0 (0) 0/0/0 2 (2) 1/0/0 1 transferred to another institution; 1 enrolled in medical school Interdepartmental Graduate Program in Genetics 2005 122 (85) 5 21 (19) 0 17 (16) 0/0/0 14 (14) 0/0/0 0 (0) 0/0/0 MS 1 0/0/0 2 (1) 0/0/0 1 left for job in industry; 1 enrolled in dental school Interdepartmental Graduate Program in Genetics 2006 130 (83) 5 35 (22) 4 20 (19) 3/0/0 18 (17) 2/0/0 0 (0) 0/0/0 0 (0) 0/0/0 2 (2) 1/0/0 1 transferred to neuroscience training program; 1 teaching science in high school Table 8A. Qualifications of Recent Predoctoral Applicants Table 8A. Qualifications of Recent Predoctoral Applicants Department / Program Year Applicant (List by Number) Previous Institution(s) Degree(s) & Year(s) GRE Scores V, Q, Adv (Percentiles) and/or MCAT Scores Support from this Undergrad Interviewed Accepted Enrolled Grant GPA (Y/N) (Y/N) (Y/N) (Y/N) 2007 Medical Scientist Training Program 1* U. of WI BSN '06 12, 11, Q, 10 3.63 Y Y Y Y 2007 Medical Scientist Training Program 2* Stanford BS '06 11, 13, N, 11 3.72 Y Y N JHU N 2007 Medical Scientist Training Program 3 Yale U. Wash. U. BA '05 MS '06 10, 9, O, 11 660 680 740 3.78 Y N N N 2007 Molecular Biophysics Program 1* U. of IL BS '06 700 730 720 4.0 Y Y Y Y 2007 Molecular Biophysics Program 2* Rutgers BS '07 710 690 680 3.36 Y Y Y Y 2007 Molecular Biophysics Program 3 Berkeley BS '07 680 710 720 3.68 Y Y N UCSF N 2007 Molecular Biophysics Program 4* U. of TX BS '07 720 690 750 (97%) (79%) (85%) 3.73 Y Y N JHU N 2007 Molecular Biophysics Program 5* Tufts U. BS '06 650 670 630 3.32 N N N N 2007 Molecular Biophysics Program 6 U. of Kyoto BS '05 480 710 720 N/A N N N N Program Statistics 32 Total Number of Applicants Number of TGE Applicants Applicants Interviewed Applicants Accepted Applicants Enrolled Applicants Supported By This Grant 9 6 7 6 3 3 Average GRE / MCAT Scores 11, 11,11 702 705 718 Average GPA 3.65 Table 9A. Qualifications of Current Predoctoral Trainees Table 9A. Qualifications of the Current Predoctoral Trainees Clearly Associated with the Training Program Department / Program Undergraduate GPA Current Research Mentor Years in Program Calendar Years Appointed to This Grant 3.63 Jones, J. '07-present None 12, 12, R, 14 3.72 Huerta, X. '05-present '06-'07 BA '05 MS '07 700 710 640 (96% 82% 84%) 3.75 Felman, R. '07-present '06-present BA '07 650 710 630 (80% 92% 83%) 3.34 TBN '07-present None Trainee (List by Number) Previous Institution(s) Degree(s) & Year(s) Biochem 1* U. of WI BSN '06 Genetics 2* MIT BS '06 Genetics 3* U. Penn. Wash. U. Genetics 4 U. Mich. GRE Scores / (Percentiles) V, Q, Adv and/or MCAT Scores 680 Program Statistics 33 Total Number of Trainees Number of TGE Trainees Average GRE / MCAT Scores 4 3 690, 705, 695 12, 12, R, 14 Average GPA 3.61 720 750 Table 10. Admissions and Completion Records of Underrepresented Individuals Table 10: Admissions and Completion Records for Underrepresented Minority (URM) Trainees, Trainees with Disabilities, and Trainees from Disadvantaged Backgrounds Clearly Associated With the Training Program Diversity Recruitment Group Trainee (List by Number) Entering Year (Pre/Post) URM Trainees 1* 2006 (Pre) Genetics T32 GM001122 F31 URM Trainees 1* 2007 (Post) Cell Biology University Fellowship Research URM Trainees 1* 2007 (Post) Chemistry Lectureship Trainees With Disabilities 1* 2004 (Pre) Pharmacology T32 GM001144 F31 Trainees With Disabilities 2* 2006 (Post) Cell Biology R01 Trainees With Disabilities 3 2007 (Post) Medicine Research Associate Trainees From Disadvantaged Backgrounds 1* 2005 (Pre) Genetics T32 GM001155 F31 34 Department / Program Source of Support and if Support by NRSA Grant In Training Completed Training Left Without Completing Training Y Current Status Career or Employment Postdoctoral Trainee UCSF Y Mentor and student both moved to another institution Y Y Postdoctoral Trainee NYU Y Career Change Y Y Postdoctoral Trainee U. Chicago Table 11. Appointments to the Training Grant for each Year of Past Award Table 11. Appointments to the Training Grant For Each Year of the Past Award (Renewal Applications Only) Grant Year 2003-2004 2004-2005 2005-2006 2006-2007 2007-2008 Predoctoral Positions Awarded (Months of Support) 10 (120) 12 (144) 14 (168) 14 (168) 14 (168) Predoctoral Trainees Appointed (Months of Support Used) 10 (120) 131 (144) 14 (168) 132 (156) 14 (168) Predoctoral URM Trainees Appointed (Months of Support) 1 (12) 2 (24) (0) 1 (12) 1 (12) Predoctoral Trainees with Disabilities Appointed (Months of Support) 1 (12) 0 (0) 1 (12) 2 (12) 0 (0) Predoctoral Trainees from Disadvantaged Background Appointed (Months of Support) 0 (0) 0 (0) 0 (0) 0 (0) 1 (12) Postdoctoral Positions Awarded (Months of Support) 4 (48) 4 (48) 4 (48) 4 (48) 4 (48) Postdoctoral Trainees With MD Appointed 1 1 2 1 2 Postdoctoral Trainees With MD/PhD Appointed 2 1 1 0 0 Postdoctoral Trainees With PhD Appointed 1 1 0 1 2 Postdoctoral Trainees With Other Degree Appointed 0 DrPH DrPH PharmD 0 Postdoctoral Trainees Appointed (Months of Support Used) 4 (48) 4 (48) 4 (48) 3 (38)3 4 (48) Postdoctoral URM Trainees Appointed (Months of Support) 1 (12) 2 (24) 0 (0) 1 (12) 1 (12) Postdoctoral Trainees with Disabilities Appointed (Months of Support) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) Postdoctoral Trainees from Disadvantaged Background Appointed (Months of Support) 0 (0) 0 (0 0 (0) 0 (0) 1 (12) 1 One trainee left after 6 months and a second trainee was appointed for the remainder of the year. One position was not filled. 3 A fourth trainee was appointed, but fell ill and dropped out after 2 months. It was then too late to recruit a replacement trainee. 2 35 Table 12A. Predoctoral Trainees Supported by this Training Grant Table 12A. Predoctoral Trainees Supported by This Training Grant (Renewal Applications Only) Predoctoral (and MSTP) Trainees (Listed Sequentially by Entering Class) Enter Source(s) of Support and Academic Year for Each Grant Year Trainee, Year of Entry Prior Degree & Grant Grant Grant Grant Grant Grant Grant Grant Grant Grant Institution (Mentor – Year Year Year Year Year Year Year Year Year Year Department / -01 -02 -03 -04 -05 -06 -07 -08 -09 -10 Program) 95-99 99-00 00-01 01-02 02-03 03-04 04-05 05-06 06-07 07-08 Cox, C., 1994 BA, Cornell Univ. (Jones-Biochem.) TG TG RG Smith, J. G., 1995 BS, Iowa State U. (Gordon-MCB) TG TG RG Johnson, J., 2002 BPharm, Duquesne (Jacobs-Virology) TG2 Smolock, Y., 2005 BS, UCLA (Rifkind-Genetics) Thomas, G., 2007 DVM, U. Penn (unassigned) RG/ TG3 TG TG RG RG UF UF TG Title of Research Project or Research Topic Current Position and Institution Degree(s) Received (Grant Support (Year) Obtained) Cloning of Human Globin Genes MD, PhD (2002) Asst. Prof. Hematology, Rutgers (50% clinical, 50% research, NIH K11) Structural Studies of MembraneBound Proteins M.S. (2001) Parke-Davis (Lab. Technician) Regulation of EBV Gene Expression PhD (2007) Postdoctoral Trainee w/C. Chen, Univ. of CA, Davis Purine Synthesis Mutants in Mammalian Cells TG TG1, TG2...Early, late…Explain use of slots! 36 In Training In Training Table 12A. Predoctoral Trainees Supported by this Training Grant (cont) Program Statistics 37 Percentage of Trainees Entering 10 Years Ago That Completed Ph.D.s Average Time to Ph.D. for Students in the Last 10 Years (not including leaves of absence) 50% 6.5 years The Narrative Background Describe data in Tables 1, 2, 3: Departmental Membership, Participating Faculty Members, Other TG Support Program Plan What students will do & why timeline? Course structure? Expectations? •Program Faculty Describe data in Tables 4, 5, 6: Faculty Grant Support, Trainees, Publication of Trainees 38 The Narrative (cont) • • • • • Proposed Training Training Program Evaluation Trainee Candidates-Recruitment Institutional Environment and Commitment Admissions and Completion Records of Trainees (Tables 7A and/or 7B) • Qualifications of Applicants (Tables 8A and/or 8B) 39 The Narrative (cont) • Current Trainee Qualifications (Tables 9A and/or 9B) • Recruitment and Retention Plan to Enhance Diversity (Tables 1, 7 A/B, Renewal Apps Table 10) • Plan for Instruction in Responsible Conduct of Research • For Renewal Applications—Progress Report (Tables 11, 12 A and/orB) 40 Narrative (cont) Human Subjects Vertebrate Animals Select Reagent Research Multiple PD/PI leadership plan Consortium/Contractural Agreements Faculty biosketches Appendix 41 The Narrative (cont) Human Subjects Vertebrate Animals Select Reagent Research Multiple PD/PI Leadership Plan Consortium/Contractual Agreements FACULTY BIOSKETCHES Appendix 42 Thank You For more info contact: Alison Hall PhD alison.hall@nih.gov