Chapter 9 Cellular Reproduction
Section 2: Mitosis and Cytokinesis
Section 3: Cell Cycle Regulation
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Chapter 9 Cellular Reproduction
9.1 Cellular Growth
Ratio of Surface Area to Volume
Chapter 9 Cellular Reproduction
9.1 Cellular Growth
As the cell grows, its volume increases much more rapidly than the surface area.
The cell might have difficulty supplying nutrients and expelling enough waste products.
Chapter 9 Cellular Reproduction
9.1 Cellular Growth
Transport of Substances
Substances move by diffusion or by motor proteins.
Diffusion over large distances is slow and inefficient.
Small cells maintain more efficient transport systems.
Chapter 9 Cellular Reproduction
9.1 Cellular Growth
Cellular Communications
The need for signaling proteins to move throughout the cell also limits cell size.
Cell size affects the ability of the cell to communicate instructions for cellular functions.
Chapter 9 Cellular Reproduction
9.1 Cellular Growth
The Cell Cycle
Cell division prevents the cell from becoming too large.
It also is the way the cell reproduces so that you grow and heal certain injuries.
Cells reproduce by a cycle of growing and dividing called the cell cycle .
Chapter 9 Cellular Reproduction
9.1 Cellular Growth
Interphase is the stage during which the cell grows, carries out cellular functions, and replicates.
Mitosis is the stage of the cell cycle during which the cell’s nucleus and nuclear material divide.
Cytokinesis is the method by which a cell’s cytoplasm divides, creating a new cell.
Chapter 9 Cellular Reproduction
9.1 Cellular Growth
The Stages of Interphase
The first stage of interphase, G
1
The cell is growing, carrying out normal cell functions, and preparing to replicate DNA.
Chapter 9 Cellular Reproduction
9.1 Cellular Growth
The Second Stage of Interphase, S
The cell copies its DNA in preparation for cell division.
Chapter 9 Cellular Reproduction
9.1 Cellular Growth
The Third Stage of Interphase, G
2
The cell prepares for the division of its nucleus.
Chapter 9 Cellular Reproduction
9.2 Mitosis and Cytokinesis
The Stages of Mitosis
Prophase
The cell’s chromatin tightens.
Sister chromatids are attached at the centromere .
Spindle fibers form in the cytoplasm.
Chapter 9 Cellular Reproduction
9.2 Mitosis and Cytokinesis
The nuclear envelope seems to disappear.
Spindle fibers attach to the sister chromatids.
Chapter 9 Cellular Reproduction
9.2 Mitosis and Cytokinesis
Metaphase
Sister chromatids are pulled along the spindle apparatus toward the center of the cell.
They line up in the middle of the cell.
Chapter 9 Cellular Reproduction
9.2 Mitosis and Cytokinesis
Anaphase
The microtubules of the spindle apparatus begin to shorten.
The sister chromatids separate.
The chromosomes move toward the poles of the cell.
Chapter 9 Cellular Reproduction
9.2 Mitosis and Cytokinesis
Telophase
The chromosomes arrive at the poles and begin to relax.
Two new nuclear membranes begin to form and the nucleoli reappear.
The spindle apparatus disassembles.
Chapter 9 Cellular Reproduction
9.2 Mitosis and Cytokinesis
Cytokinesis
In animal cells, microfilaments constrict, or pinch, the cytoplasm.
In plant cells, a new structure, called a cell plate, forms.
Chapter 9 Cellular Reproduction
Chapter 9 Cellular Reproduction
9.3 Cell Cycle Regulation
Normal Cell Cycle
Different cyclin/CDK combinations signal other activities, including DNA replication, protein synthesis, and nuclear division throughout the cell cycle.
Chapter 9 Cellular Reproduction
9.3 Cell Cycle Regulation
Quality Control Checkpoints
The cell cycle has built-in checkpoints that monitor the cycle and can stop it if something goes wrong.
Spindle checkpoints also have been identified in mitosis.
Chapter 9 Cellular Reproduction
9.3 Cell Cycle Regulation
Abnormal Cell Cycle: Cancer
Cancer is the uncontrolled growth and division of cells.
Cancer cells can kill an organism by crowding out normal cells, resulting in the loss of tissue function.
Chapter 9 Cellular Reproduction
9.3 Cell Cycle Regulation
Causes of Cancer
The changes that occur in the regulation of cell growth and division of cancer cells are due to mutations.
Various environmental factors can affect the occurrence of cancer cells.
Chapter 9 Cellular Reproduction
9.3 Cell Cycle Regulation
Apoptosis
Programmed cell death
Cells going through apoptosis actually shrink and shrivel in a controlled process.
Chapter 9 Cellular Reproduction
9.3 Cell Cycle Regulation
Stem Cells
Unspecialized cells that can develop into specialized cells when under the right conditions
Chapter 9 Cellular Reproduction
9.3 Cell Cycle Regulation
Embryonic Stem Cells
After fertilization, the resulting mass of cells divides repeatedly until there are about
100 –150 cells. These cells have not become specialized.
Chapter 9 Cellular Reproduction
9.3 Cell Cycle Regulation
Adult Stem Cells
Found in various tissues in the body and might be used to maintain and repair the same kind of tissue
Less controversial because the adult stem cells can be obtained with the consent of their donor
Cellular
Reproduction
Chapter 9 Cellular Reproduction
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Chapter 9 Cellular Reproduction
Chapter Diagnostic
Questions
Which is the first phase of mitosis?
A.
interphase
B.
prophase
C.
metaphase
D.
telophase
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
Chapter Diagnostic
Questions
During what phase do the sister chromatids line up in the middle of the cell?
A.
interphase
B.
metaphase
C.
anaphase
D.
telophase
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
Chapter Diagnostic
Questions
Which is not a phase of the cell cycle?
A.
cytokinesis
B.
interphase
C.
apoptosis
D.
mitosis
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
9.1 Formative
Questions
Which can more efficiently supply nutrients and expel waste products?
A.
larger cells
B.
smaller cells
C.
cells with lower surface area to volume ratio
D.
cells shaped like a cube
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
9.1 Formative
Questions
At what stage does a cell spend most of its life?
A.
cytokinesis
B.
interphase
C.
mitosis
D.
synthesis
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
9.1 Formative
Questions
What happens in the cell during cytokinesis?
A.
The cell grows and carries out normal functions.
B.
The cell copies its DNA and forms chromosomes.
C.
The cell’s nucleus and nuclear material divide.
D.
The cell’s cytoplasm divides.
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
9.2 Formative
Questions
In what stage of the cell cycle does the cell’s replicated genetic material separate?
A.
cytokinesis
B.
interphase
C.
mitosis
D.
prophase
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
9.2 Formative
Questions
Which diagram shows anaphase?
A.
B.
C.
D.
A
0%
1.
2.
3.
4.
0%
B
A
B
C
D
0%
C
0%
D
Chapter 9 Cellular Reproduction
9.2 Formative
Questions
At the end of mitosis the nuclear material is divided and two new cells have formed.
A.
true
B.
false 1. A
A
2. B
0% 0%
B
Chapter 9 Cellular Reproduction
9.3 Formative
Questions
What are the “key and ignition” that start the various activities in the cell cycle?
A.
chromatin and chromosomes
B.
cyclin and CDKs
C.
microtubules and spindle fibers
D.
protein and ribosomes
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
9.3 Formative
Questions
Which of these cancer-causing substances or agents is impossible to avoid completely?
A.
chemicals such as asbestos
B.
food and drinks that the FDA warns may contain carcinogens
C.
tobacco and second-hand smoke
D.
ultraviolet radiation from the Sun
A
0%
1.
2.
3.
4.
0%
B
A
B
C
D
0%
C
0%
D
Chapter 9 Cellular Reproduction
9.3 Formative
Questions
What is the term for the programmed death of cells that are damaged beyond repair or have harmful changes in their DNA?
A.
apoptosis
B.
carcinogens
C.
cytokinesis
D.
mitosis
1.
2.
3.
4.
A
B
C
D
A
0% 0%
B
0%
C
0%
D
Chapter 9 Cellular Reproduction
9.3 Formative
Questions
Which cells are not locked into becoming one particular kind of cell and are capable of developing into specialized tissues?
A.
apoptotic cells
B.
cancer cells
C.
prokaryotic cells
D.
stem cells
1.
2.
3.
4.
A
B
C
D
A
0% 0%
B
0%
C
0%
D
Chapter 9 Cellular Reproduction
Chapter Assessment
Questions
This cell has completed what stage of mitosis?
A.
anaphase
B.
interphase
C.
metaphase
D.
telophase
1.
2.
3.
4.
A
B
C
D
A
0% 0%
B
0%
C
0%
D
Chapter 9 Cellular Reproduction
Chapter Assessment
Questions
What term is used to describe programmed cell death?
A.
apoptosis
B.
anaphase
C.
necrosis
D.
cyclins
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
Chapter Assessment
Questions
What is the role of cyclins in a cell?
A.
to control the movement of microtubules
B.
to signal for the cell to divide
C.
to stimulate the breakdown of the nuclear membrane
D.
to cause the nucleolus to disappear
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
Standardized Test
Practice
Which cell has the lowest ratio of surface area to volume?
C
B
A
0%
1.
A
2.
B
3.
0%
C
0%
A B C
Chapter 9 Cellular Reproduction
Standardized Test
Practice
At what stage of interphase does the cell take inventory and make sure it is ready for the division of its nucleus?
A.
G
1
B.
S
C.
G
2
D.
M
1.
2.
3.
4.
A
B
C
D
A
0% 0%
B
0%
C
0%
D
Chapter 9 Cellular Reproduction
Standardized Test
Practice
Which occurs in plant cells but not animal cells during the cell cycle?
A.
formation of a cell plate
B.
formation of microtubules
C.
formation of a cleavage furrow at the equator of the cell
D.
movement of chromosomes to the poles of the cell
A
0% 0%
B
1.
2.
3.
4.
0%
C
A
B
C
D
0%
D
Chapter 9 Cellular Reproduction
Standardized Test
Practice
Multiple changes in DNA are required to change an abnormal cell into a cancer cell.
A.
true
B.
false
A
0%
1. A
2. B
0%
B
Chapter 9 Cellular Reproduction
Standardized Test
Practice
Which is not a condition that can result in cancer?
A.
a failure in the control mechanisms that regulate the cell cycle
B.
a failure in the repair systems that fix changes or damage to DNA
C.
a failure of the spindle fibers to move chromosomes during mitosis
D.
mutations or changes in segments of DNA that control protein production
A
0% 0%
B
1.
2.
3.
4.
A
B
C
D
0%
C
0%
D
Chapter 9 Cellular Reproduction
Glencoe Biology Transparencies
Chapter 9 Cellular Reproduction
Image Bank
Chapter 9 Cellular Reproduction
Vocabulary
Section 1 cell cycle interphase mitosis cytokinesis chromosome chromatin
Chapter 9 Cellular Reproduction
Vocabulary
Section 2 prophase sister chromatid centromere spindle apparatus metaphase anaphase telophase
Chapter 9 Cellular Reproduction
Vocabulary
Section 3 cyclin cyclin-dependent kinase cancer carcinogen apoptosis stem cell
Chapter 9 Cellular Reproduction
Animation
Chapter 9 Cellular Reproduction