Europass
Curriculum
Vitae
Personal
information
First name(s) /
Surname(s)
Maria Pia
Felli
Address(es)
Telephone(s)
Fax(es)
E-mail
Department of Experimental Medicine,291, Viale Regina Elena, 00161, Roma, Italy
(39 06)49255673
Mobile:
(39 06)49255671
mariapia.felli@uniroma1.it
Nationality italian
Date of birth
Gender
Occupational (S s/d)
field General Pathology (MED/04)
Work
experience
Dates From 2001: Associate Professor of General Pathology in the Medical School of the Faculty of Medicine and Surgery of the
University "La Sapienza" of Rome, Italy, Department of Experimental Medicine, Faculty of Medicine and Surgery, University
of Rome, Italy.
1995-2001: Investigator, Department of Experimental Medicine, University of L’Aquila, L’Aquila, Italy
Occupation or
position held
Main activities
and
responsibilities
Name and
address of
employer
Sector
Associate Professor of General Pathology
Research, teaching, tutorial
Laboratory of Molecular Pathology, Department of Experimental Medicine, University “Sapienza”- Policlinico “UmbertoI”,
Viale Regina Elena 291, 00161 Roma
Molecular pathology
Education
and training
Dates 1994-95 Post-Doc in Biotechnology and Biometry, University of L’Aquila, L’Aquila, Italy
1993: PhD doctor in Biotechnology and Biometry, University of L’Aquila, L’Aquila, Italy
Title of 1986: License as a Biologist, University “La Sapienza” of Rome, Rome, Italy
qualification 1984: Degree cum laude in Biology, University “La Sapienza” of Rome, Rome, Italy
awarded
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Name and University “La Sapienza” of Rome, Rome, Italy
type of University of L’Aquila, L’Aquila, Italy
organisation
providing
education and
training
Personal Cell signalling and molecular pathways involved in T cell development and leukemogenesis in “in vivo” and “in vitro”
skills and experimental models.
competences
Mother
tongue(s)
Other
language(s)
Italian
English, Spanish
Selfassessment
Understanding
Listening
European
level (*)
Reading
Language
English
B2
Independent
user
B2
Independent
user
Language
Spanish
A2
Basic user
A2
Basic user
Speaking
Spoken interaction
Writing
Spoken production
C1 Proficient user C1 Proficient user C1 Proficient user
A2
Basic user
A1
Basic user
(*) Common European Framework of Reference for Languages
Additional Include here any other information that may be relevant, for example contact persons, references, etc.
information
R
Receiving
Annexes List any items attached.
Scientific
Publication
27 articles
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A1
Basic user
Works
1) CAMPESE A.F., GRAZIOLI P., SCAFETTA G., NOCE C., VERKHOVSKAIA S., MARI C., FELLI M.P., GULINO A., and SCREPANTI I. (2012). Deletion of NF­kB/p50 influences the outcome of Notch3­dependent T cell leukemia. JOURNAL OF IMMUNOLOGY, 188, May 2) BARBARULO A, GRAZIOLI P, CAMPESE A.F, BELLAVIA D, DI MARIO G, PELULLO M, CIUFFETTA A, COLANTONI S, VACCA A, FRATI L, GULINO A, FELLI M., SCREPANTI I (2011).
Notch3 and canonical NF­kB signaling pathways cooperatively regulate Foxp3 transcription. JOURNAL OF IMMUNOLOGY, vol. 186; p. 6199­6206. 3) MATTIELLO T, GUERRIERO R, LOTTI L.V, TRIFIRÒ E, FELLI M., BARBARULO A, PUCCI B, GAZZANIGA P, GAUDIO C, FRATI L, F. PULCINELLI (2011). Aspirin extrusion from human platelets through multidrug resistance protein­4 mediated transport: evidence of a reduced drug action in patients after coronary artery bypass grafting. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 58; p. 752­761.
4) BELLAVIA D, CHECQUOLO S, CAMPESE A. F, FELLI M., GULINO A, SCREPANTI I (2008). Notch3: from subtle structural differences to functional diversity. ONCOGENE, vol. 27; p. 5092­5098.
5) TALORA C, CAMPESE A.F, BELLAVIA D, FELLI M., VACCA A, GULINO A, SCREPANTI I (2008). Notch signaling and diseases: An evolutionary journey from a simple beginning to complex outcomes. BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, vol. 1782; p.
489­497.
6) VACCA A, FELLI M., PALERMO R, DI MARIO G, CALCE A, DI GIOVINE M, FRATI L, GULINO A, SCREPANTI I (2006). Notch3 and pre­TCR interaction unveils distinct NF­kappaB pathways in T­
cell development and leukemia. EMBO JOURNAL, vol. 25; p. 1000­1008.
7) FELLI M., A. VACCA, A. CALCE, D. BELLAVIA, A.F. CAMPESE, R. GRILLO, M. DI GIOVINE, S. CHECQUOLO, C. TALORA, R. PALERMO, G. DI MARIO, L. FRATI, A. GULINO, AND I. SCREPANTI (2005). “PKCtheta mediates pre­TCR signaling and contributes to Notch3­induced T cell leukemia”. ONCOGENE, vol. 24; p. 992­1000.
8) BELLAVIA D., CAMPESE A.F., ALESSE E., VACCA A., FELLI M., BALESTRI A., STOPPACCIARO A., TIVERON C., TATANGELO L., GIOVARELLI M., GAETANO C., RUCO L., HOFFMAN E.S., HAYDAY A.C., LENDAHL U., FRATI L., GULINO A., SCREPANTI I. (2000). Constitutive activation of NF­kB and T cell leukemia/lymphoma in Notch3 transgenic mice. EMBO JOURNAL, vol. 19; p. 3337­3348.
9) MARODER M., BELLAVIA D., VACCA A., FELLI M., SCREPANTI I. (2000). The thymus at the crossroad of the neuroimmune interactions. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 917; p. 741­747.
10) SALVATORI L., RAVENNA L., FELLI M., CARDILLO M.R., RUSSO M.A., FRATI L., GULINO A., PETRANGELI E. (2000). Identification of an estrogen­mediated DNA­binding independent transactivation pathway on the EGF receptor gene promoter. ENDOCRINOLOGY, vol. 141; p. 2266­
2274.
11) STORTO M., DE GRAZIA U., BATTAGLIA G., FELLI M., MARODER M., GULINO A., RAGONA G., NICOLETTI F., SCREPANTI I, FRATI L., CALOGERO A. (2000). Expression of metabotropic glutamate receptors in murine thymocytes and thymic stromal cells. JOURNAL OF NEUROIMMUNOLOGY, vol. 109; p. 112­120.
12) FELLI M., MARODER M., MITSIADIS T.M., CAMPESE A.F., SCARPA S., BELLAVIA D., VACCA A., MANN R.S., FRATI L, LENDAHL U., GULINO A. SCREPANTI I. (1999). Expression pattern of Notch1, 2 and 3 and Jagged 1 and 2 in lymphoid and stromal thymus components: distinct ligand­
receptor interactions in thymocyte development. INTERNATIONAL IMMUNOLOGY, vol. 11; p. 1017­
1025.
13) FELLI M., MOSCHELLA C., FARINA A.R., ALESSE E., SCREPANTI I., TETI D., FRATI L., GULINO A. (1996). Prostaglandin E2 inhibits the interleukin­2 promoter activity through down­
regulation of the oct­dependent transcription of the octamer motif. CELLULAR IMMUNOLOGY, vol. 172; p. 229­234.
14) RAVENNA L., LUBRANO C., DI SILVERIO F., VACCA A., FELLI M., MARODER M., D'ERAMO G., SCIARRA F., FRATI L., GULINO A., PETRANGELI E. (1995). Androgenic and antiandrogenic control on Epidermal Growth Factor, Epidermal Growth Factor Receptor, and Androgen Receptor expression in human prostate cancer cell line LN CaP. PROSTATE, vol. 26; p. 290­298.
15) FELLI M., DE GRAZIA U., VACCA A., FARINA A.R., MARODER M., CAPPABIANCA L., MECO D., FARINA M., SCREPANTI I., FRATI L., GULINO A. (1994). Positive and negative regulation of the
composite octamer motif of the interleukin 2 enhancer by AP­1, OCT­2, and Retinoic Acid Receptor. JOURNAL OF EXPERIMENTAL MEDICINE, vol. 180; p. 1485­1497.
16) MARODER M., FARINA A.R., VACCA A., FELLI M., MECO D., SCREPANTI I., FRATI L., GULINO A. (1993). Cell specific bifunctional role of jun oncogene, family members upon glucocorticoid
receptor­dependent transcription. MOLECULAR ENDOCRINOLOGY, vol. 7; p. 570­584.
17) VACCA A., FELLI M., FARINA A.R., MARTINOTTI S, MARODER M., SCREPANTI I., MECO D., Page 3/5 - Curriculum vitae of
Surname(s) First name(s)
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18) DE CAPOA A., ALEIXANDRE C., FELLI M., RAVENNA L., COSTANTINO M.A., GIANCOTTI P.,
VICENTI O., POGGESI I., GRAPPELLI C., MILLER D.A. (1991). Inheritance of ribosomal gene
activity and level of DNA methylation of individual gene clusters in a three generation family. HUMAN
GENETICS, vol. 88; p. 146-152.
19) FELLI M., VACCA A., MECO D., SCREPANTI, FARINA A.R., MARODER M., MARTINOTTI S.,
PETRANGELI E., FRATI L., GULINO A. (1991). Retinoic acid-induced down-regulation of the
Interleukin-2 promoter via cis-regulatory sequences containing an octamer motif. MOLECULAR AND
CELLULAR BIOLOGY, vol. 11; p. 4771-4778.
20) SCREPANTI I., FELLI M., TONIATO E., MECO D., MARTINOTTI S., FRATI L., SANTONI A.,
GULINO A (1991). Enhancament of natural killer cell susceptibility of human breast cancer cells by
estradiol and v-Ha-ras oncogene. INTERNATIONAL JOURNAL OF CANCER, vol. 47; p. 445-449
21) VACCA A., MARTINOTTI S., SCREPANTI I., MARODER M., FELLI M., FARINA A.R., GISMONDI
A., SANTONI A., FRATI L., GULINO A. (1990). Transcriptional regulation of the interluekin 2 gene by
glucocorticoid hormones . THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 265; p. 8075-8080.
22) VACCA A, MARTINOTTI S, SCREPANTI I, MARODER M, FELLI M., FARINA AR, GISMONDI A,
SANTONI A, FRATI L, GULINO A. (1990). Transcriptional regulation of the interleukin 2 gene by
glucocorticoid hormones. Role of steroid receptor and antigen-responsive 5'-flanking sequences. THE
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 265; p. 8075-8080.
23) BALDINI A., FELLI M., RAVENNA L., CAMAIONI A., DE CAPOA A., SPADONI G.L.,
CIANFARANI S., BOSCHERINI B. (1988). Differential ribosomal gene responsiveness to human
growth hormone is visualized by selective silver staining. CYTOGENETICS AND CELL GENETICS,
vol. 47; p. 22-25, ISSN: 0301-0171
24) DE CAPOA A., FELLI M., BALDINI A., ROCCHI M., ARCHIDIACONO N., ALEIXANDRE C.,
MILLE O.J., MILLER D.A. (1988). Relationship between the number and function of human ribosomal
genes. HUMAN GENETICS, vol. 79; p. 301-304, ISSN: 0340-6717
25) SPADONI G.L., CIANFARANI S., BALDINI A., RAVENNA L., FELLI M., CAMAIONI A., MANCA
BITTI M.L., SCIRÈ G., BOSCHERINI B., DE CAPOA A. (1988). Laron dwarfism: cellular
unresponsiveness to GH demonstrated on cultured lymphocytes by a cytochemical method. HORMONE
AND METABOLIC RESEARCH, vol. 20; p. 450-452, ISSN: 0018-5043
26) BALDINI A., CAMAIONI A., DE CAPOA A., FELLI M., MARLEKAJ P., RAVENNA L.,
CIANFARANI S., SPADONI G.L., BOSCHERINI B. (1986). Growth hormone-induced activation of
rRNA gene clusters:cellular responses of normal subjects and pituitaric dwarfs. CELL BIOLOGY
INTERNATIONAL REPORTS, vol. 10; p. 202, ISSN: 0309-1651
27) DE CAPOA A.ARCHIDIACONO N., MARLEKAJ P., BALDINI A., FELLI M., ARCHIDIACONO N.,
CIANFARANI S., SPADONI G.L., BOSCHERINI B. (1986). Growth hormone-induced regulation of
rRNA gene activity in human cultured cells. HORMONE AND METABOLIC RESEARCH, vol. 18; p.
574-575, ISSN: 0018-5043
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© European Union, 2004-2010 24082010
Textbooks
(Chapters, etc.)
1. VACCA A, FELLI M.P., A.R. FARINA, D. MECO, M. MARODER, I. SCREPANTI, S. MARTINOTTI, E. PETRANGELI, U.
DE GRAZIA, L. FRATI, A. GULINO (1993). Nuclear hormone receptor interference with interleukin 2 promoter activating
signals. Progress in Endocrinology. p. 42-44, NEW YORK: The Partrhenon Publishing Group.
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© European Union, 2004-2010 24082010