BIOL 121 – The Unity of Life Instructor: DW Buckalew Office: 305A Sciences Office Hours: M 3:00 – 5:00 pm F 8:00-10:00 am Welcome aboard! The Biosphere is the limit!! How to Succeed in Science courses •Attendance is a MUST – you will need to take notes! •Timeliness is a MUST – you need to be present to take notes! •Read the textbook from this day forward…. •Begin projects early •Don’t be rude – turn off cell phones, refrain from talking •Biology I is essentially Intro Biochemistry – look at the topics! •You’ve seen/heard much of the info before? Probably so. •You’ve had to synthesize the amount req’d for Biology I? Probably not. How to Succeed in Science courses COMMUNICATE – talk with faculty when problems arise (notice the word “IF” was not used) “ROLL WITH THE PUNCHES” – bounce back from low test/quiz scores DELAY IMMEDIATE GRATIFICATION – the pursuit of the degree is difficult KEEP YOUR EYES ON THE PRIZE – graduation is closer than you think! Work Hard!! 1) Brett Montgomery ('03) MD program at EVMS 2) Matthew Kren ('04) MS Biology – VCU; DVM Program – Ross University 3) Renae Trombley ('04) Doctoral program - VCU/MCV Physical Therapy 4) Richard Scherer ('04) Doctoral program - VCU/MCV Physical Therapy 5) Brian Belliveau ('05) Ph.D. program in Molecular Biology at Notre Dame 6) Nick Hopson ('05) Doctoral program - VCU/MCV Physical Therapy 7) Amber Weems ('05) VCU School of Dentistry 8) Ryan Dunn ('05) MD program in Pathology at Duke University 9) Paul Hetterich ('05) MS in Clinical Micro/Immuno at VCU/MCV 10) Stephen "Matt" Akers ('04) MD/PhD program at West Virginia University 11) Frankie Simmons ('03) MD program - Howard University 12) Stephanie Thomas ('04) Ph.D. Program at Old Dominion University 14) Stuart Bertsch ('05) MD program – VCU/MCV 15) Sara Lee ('05) MS program – Forensics - Marshall University 16) Katie Wells ('05) Doctoral program - Shenandoah University Physical Therapy 17) Laura Wooldridge ('05) Physician's Assistant program - Shenandoah University 18) Casey Dertzbaugh ('06) Doctoral program VCU/MCV Physical Therapy 19) Adrienne Hampton ('05) MD program - Northwestern University 20) Kelley Jernigan (06) Nursing Program at VCU 21) Quintin Lewis (06) Ph. D. Program in Molecular Biology – VCU 22) Jerry McCoy ('05) Teaching at Emporia Private High School 23) David Walker ('06) NOVA University School of Dentistry 24) Carolyn Howard ('06) MS program in Occupational Therapy - JMU 25) Crystal Freels ('06) Science teacher – Roanoke school district 26) Ray Stephens ('06) VCU Dental School 27) Albert Tuono ('06) DOM program - WV School of Osteopathic Medicine 28) Colleen Schamber ('06) MS in Biomedical Engineering – UVA 29) Nicole Woznick ('06) PharmD program - VCU 30) Kelly Brake ('06) - VCU School of Nursing 31) Catherine Dunn ('05) - Molecular lab tech at Cornell Medical College 32) Chelsea Norton ('05) - Lab specialist - Wyeth Pharmaceuticals 33) Catherine Melvin ('05) - Ph.D program in Microbiology - GMU 34) Christina Stewart ('06) - Lab technician - VCLS Richmond, VA 35) Michelle Wagner ('05) - VCU School of Nursing 36) Ashley Martin ('04) - MS program in Clinical Lab Sciences - VCU/MCV 37) Jason Chambers (06) – MS in Marine Biology – UNC-Wilmington 38) Tiffany Crane (07) – Post-Bacc – University of Cincinnati 39) Jennifer Smith Doss (07) – Officer, Va DCR – Fish and Wildlife 40) Michael Edwards (07) – DVM program – VA Tech 41) Jason Ferguson (07) – MS program in Fisheries – Univ Tennessee 42) Oscar Gonzalez (07) – Biomedical Engineering – VCU 43) Jane Ashley Hawkins (07) – BS Nursing program – Univ of South Carolina 44) Michael Joyce (07) – Post- Bacc – Pre-medical program – VCU 45) Courtney Kreft (07) – 2nd Lt – MASH surgical unit – Afghanistan 46) Joel Rowe (07) – MD program – VCU/MCV 47) Amanda Simmons (07) – MS in Microbiology – ODU 48) Whitney Slack (07) – MS Program in Nursing VCU/MCV 49) Emily Sturgill (07) – BS Nursing Program – GMU 50) Natalie Haines (07) – QC Biologist – American Type Culture Collection 51) Matt Lusk (06) – UNC Coastal Studies Institute Your name here (‘11) – attending graduate school at…. - attending professional school at… - teaching science at…… -lab/field scientist at/for…. Your future begins today!! Hot Topics in Biology: Emerging/Re-emerging diseases Hot Topics in Biology: Global Warming Hot Topics in Biology: Decline in Biodiversity Hot Topics in Biology: Fetal Stem Cells Career options – what’s out there • Professional scientists – often immersed in research and development academia government industry – Often requires a Ph.D. or other advanced degree degree • Science-trained professionals – Often employed by industry, business, education, and government in different ways – Usually requires a M.S. or equivalent degree You can enter many science careers with a B.S. •Research technician •Lab coordinator •Regulatory agent •Quality control specialist •Life science product sales Biology B.S. with additional study: •Science journalism •Medical technology •1° and 2° education •Pharmaceutical/agrichemical sales •Bioinformatics including law enforcement •Museum curator Biology B.S. combined with other degree (i.e., MBA, JD) •High tech business or hospital management •Financial analyst of biotechnology firms •Patent law/technology transfer/environmental law •Environmental engineering M.D.: Biology Ph.D. : •Average of 5-7 years beyond B.S. •Average of 4 years beyond PLUS 4+ years of residency/specialized training •College/university teacher •Research director in academia, government, and industry Typically obtained via paid assistantships •Other professional medical degrees… P.A. D.V.M PharmD. D.D.S. D.P.T. D.P.M. D.O.M. The number of Biology Ph.D.’s employed in business and industry has increased steadily…over 50% of new Ph.D.’s are employed outside academia (Tobias, 2005) Over 1/3 have moved into management roles So let’s get started in the quest…. Chapter 1- The Science of Biology • Biology is “the study of life” I. Characteristics of life: – – – – – – – Cellular organization Order Sensitivity Growth, development, and reproduction Energy utilization Evolutionary adaptation Homeostasis II. The Hierarchical organization of life • At the cellular level… Atoms join to form molecules Molecules join to form larger molecules (e.g. organics) Large molecules are assembled to form organelles Organelles are contained within a larger organized cell II. The Hierarchical organization of life • At the organismal level… Cells organized in 3 levels: tissue organ organ system The set of organ systems form the intact organism II. The Hierarchical organization of life • At the population level… Individual organisms form populations All populations of a single type of organism constitute the species All populations of different organisms living together in one place make a community The biological community PLUS the abiotic factors make up an ecosystem III. The Process of Science (science = L. “to know”) Charles Darwin (1809-1882) sought natural rather than supernatural causes for the unity/diversity of nature and, in doing so, revolutionized biology. Published the then controversial book, On the Origin of Species…etc in 1859. The Process of Science • Science seeks answers to natural phenomena – Activities that can be observed and measured – Activities that can be verified through testing The Process of Science • Science uses 2 ways to approach problem solving… – Inductive reasoning = Generalization that summarizes many observations – Deductive reasoning = Hypothesis testing and “if-then logic” – reasoning flows from general to specific How Science Is Done Science is a systematic process of testing alternative hypotheses Unifying Themes of Science • Cell theory – Robert Hooke (1665) to Anton van Leeuwenhoek (1700) to Schleiden and Schwann (1839) – All living organisms are made of cells, and all living cells come from other living cells. – Later, it was proposed that all cell came from pre-existing cells. • Molecular theory – “central dogma of molecular biology” – DNA is the molecule of inheritance – DNA encodes genes which make-up and control living organisms. – DNA RNA Protein Unifying Themes of Science • Evolutionary change – Life-forms have evolved varying characteristics to adapt to varied environments. • Evolutionary conservation – Some characteristics of earlier organisms are preserved and passed on to future generations. Articles on reserve for 1st Article Review • Nestle, M. 2007. Eating made simple. Scientific American. 297: 60-69. (Sept) • Grossman, D. 2004. Spring forward. Scientific American. 290: 84-92. (Jan) • Rennie, J. 2002. 15 Answers to creationist nonsense. Scientific American. 287: 78-85.(July) LWU electronic reserve: http://readpac.longwood.edu/search/r?biol+121