International Workshop CHRONIC PAIN IN NEUROREHABILITATION an update of the Italian Consensus Conference June 12-14, 2014 IRCCS Fondazione Santa Lucia, Rome, Italy Chairmen: MG Buzzi, G Cruccu, G Sandrini June 12 13:30 – 14:15 Registration 14:15 – 15:00 Introduction Luigi Amadio – General Director FSL Carlo Caltagirone – Scientific Director FSL Maria Gabriella Buzzi – Chairman Giorgio Cruccu – Chairman Giorgio Sandrini – Chairman and EFNRS President Vincenzo Saraceni – Chairman and SIMFER President 15:00 – 16:45 Chairmen: G Cruccu – G Sandrini Epidemiology and patho-physiology of chronic pain (1:45) The impact of chronic pain: why to care and cure 30' – M. Musicco Pathophysiology of neuropatic pain 30' – A Truini Pathophysiology of muscle-skeletal pain 30' - OK Andersen Discussion 15' 16:45 – 17:15 Tea break 17:15 – 19:30 Chairmen: V Saraceni – R Formisano Update from the Italian Consensus Conference (ICC) on Chronic Pain in Neurorehabilitation (Part 1) (2:15) From Law to Care and Cure: aims and methodology of the ICC 20' – S. Tamburin Ageing and neuro-degeneration 20' – A Bianchetti Severe acquired brain injury and Disorders of consciousness 20' - A De Tanti Spinal cord injury 20' – M Molinari Stroke 20' – S Paolucci Multiple sclerosis 20' – C Solaro / R Bergamaschi Discussion 15' June 13 08:45 – 11:00 – Chairmen: MG Grasso – N Smania Update from the Italian Consensus Conference (ICC) on Chronic Pain in Neurorehabilitation (Part II) (2:15) Movement disorders 20' – G De Fazio, M Tinazzi Neuomuscular diseases 20' – F Ferraro Spasticity 20' – P Cicinelli Phantom limb 20' – S Brunelli Chronic headaches 20' – MG Buzzi Osteoarticular pain 20'' – R Casale Discussion 15' 11:00 – 11:20 Coffee break 11:20 – 13:50 – Chairmen: R Torta, MG Buzzi Exploring the nociception control system in animals and humans (2:30) Animal models of chronic pain 30' – L Berliocchi Clinical scales 30' – N Attal Laboratory tools 30' – V Tugnoli Nociceptive reflexes 20' - M Serrao Measuring anxiety and depression in chronic pain 30' – R Torta Discussion 10' 13:50 – 14:30 Lunch time 14:30 – 16:45 – Chairmen: G Cruccu – F Nicoletti Pharmacological aids (2:15) Molecular biology of pain 30' – F Nicoletti Neurogenic neuroinflammation and oxidative stress: co-conspirators in neurodegeneration and in neuropathic Pain 30’ S Cuzzocrea Targeting receptors, channels, systems 30' T Dickinson Guidelines 30' – G Cruccu Discussion 15' 16:45 – 17:15 – Tea break 17:15 – 19:15 – Italian Consensus Conference Round Table: next steps Chairmen: S Paolucci, S Tamburin, G Sandrini June 14 8:45 – 10:30 – Chairman: P Martelletti, M Romano Training session: Local treatment of headache with onabotulinum toxin A (1:45) Pharmacology and mechanism of action of onabotulinum toxin A 30' – P Geppetti Evidences from clinical trials 30' – C Tassorelli Methodology – 30' – Negro A Discussion 15' 10:30 – 11:00 Coffee break 11:00 – 13:15 – Chairmen: L Saltuari, C Cisari The integrated approach to pain in neurorehabilitation’ (2:15) Physical Therapy and Rehabilitation 20' – C Cisari Physiotherapy 20' – C Geroin Intrathecal delivery 30' – L Saltuari Interventional approaches (NCH) 30' – C Bonezzi Psycotherapy – 20' G Castelnuovo Discussion 15' 13:15 – 13:30 Concluding remarks and CME Questionnaires (0:45) MG Buzzi, G Cruccu, G Sandrini Scientific Secretary Mariagrazia D'Ippolito Stefano Tamburin Marco Tramontano Andrea Truini