CURRICULUM VITAE - GRAZIAMARIA CORBI, MD, PHD
Personal Details
Nazionality:
Date of birth:
Place of birth:
Address:
Phone:
e-mail:
Italian
09-02-1974
Naples
via Campitelli 13, 80055 Portici (NA) –Italy
+393339378729
graziamaria.corbi@unimol.it
Education and
qualifications
1998 Degree in Medicine with 110/110 cum laude at the Second University of Naples,
Faculty of Medicine.
1998 Admission with Grant to Specialization Course in Geriatric Medicine at the Second
University of Naples, Faculty of Medicine.
2002 Postgraduate Course “Nuclear Cardiology in Practice” at the National Heart and Lung
Institute (NHLI) of Imperial College -London.
2002 Postgraduate Course “Advances in Cardiology: the right heart” at the National Heart
and Lung Institute (NHLI) of Imperial College -London.
2002 Postgraduate Course “Hammersmith Echocardiology” at the National Heart and Lung
Institute (NHLI) of Imperial College -London.
2002 Immediate Life Support Course at the Royal Brompton Hospital, London.
2002 Residency in Geriatrics with vote 50/50 cum laude, at the Second University of
Naples, Faculty of Medicine.
2002 Admission with Grant to PhD Course in Geriatric Pathophysiology at the Second
University of Naples, Faculty of Medicine.
2004 V Diploma Course in " Cardiac Rehabilitation" achieved at the “Federico II” University
of Naples.
2006 PhD in Geriatric Pathophysiology at the Second University of Naples, Faculty of
Medicine, Faculty of Medicine.
2008-2010 Tenure-track researcher at Dept of Health Sciences of University of Molise.
2010 Contract for coordinated and continuative cooperation with the Dept of Medicine and
Health Sciences of University of Molise.
2010 to date Assistant Professor at Dept of Medicine and Health Sciences of University of
Molise.
Experiences
2000 Participant in the Inter-university Research Program (PRIN) entitled “Profile of the
gene expression in aged heart and related changes induced by exercise training” granted
by the Ministry for Education, University and Research (MIUR - Ministero dell'Istruzione,
dell'Università e della Ricerca) prot. 2001064957_003.
2000 Visitor at the National Heart & Lung Institute (NHLI), Imperial College, Royal
Brompton Hospital, London.
2001-2002 Research Fellow at the National Heart & Lung Institute (NHLI), Imperial
College, Cardiology Division Hammersmith Hospital, London, with research projects on
“Refractory Angina” and “ECG Changes during Dobutamine Stress Echocardiography”.
2003 Participant in the Inter-university Research Program (PRIN) entitled "Reacutization
Risk of heart failure in elderly and related precipitating factors: Role of reduced
erithropoietic function" granted by the Ministry for Education, University and Research
(MIUR - Ministero dell'Istruzione, dell'Università e della Ricerca) prot. 2003069752_003.
2004-2007 Geriatric Physician at the Alzheimer Evaluation Unit of the ASL NA1 –District 46
of Naples.
2005 Participant with the Operative Unity of the University of Molise in the Research Study
granted by the Italian Agency for Drugs (AIFA) entitled “Evaluation of an
educative/informative strategy on drugs use in elderly population with chronic-degenerative
diseases in several care setting: a controlled randomised study”. Code: FARM54J8WX.
2007 Participant in the Inter-university Research Program (PRIN) entitled “Ischemia, aging
and organ damage: molecular mechanisms and new therapeutic targets” granted by the
Ministry for Education, University and Research (MIUR - Ministero dell'Istruzione,
dell'Università e della Ricerca) prot. 20074MSWY.
2009 Participant with the Operative Unity of the University of Molise in the Research Study
granted by the Italian Agency for Drugs (AIFA) entitled "Prospective validation of IWPC
pharmacogenetic algorithm for estimating the appropriateinitial dose of warfarin in elderly
people (≥65 years) with heart valves or non valvular atrial fibrillation and comorbidity"
Code: FARM9JNT9Y.
Since 2004 to 2010 Basic Science Research collaboration at the Dept of Experimental
Medicine lab of the Faculty of Medicine and Surgery -Second University of Naples.
2010 to date Basic Science Research collaboration with Prof. A. Filippelli, at the
Department of Medicine and Surgery, University of Salerno, with acquisition of theoretical
and practical knowledge in molecular biology
Since 2005 to date Teaching activity for students at Dept of Medicine and Health Sciences
of University of Molise
Since 2013 to date Teaching activity for PhD students of the Doctorate Course of
"Biological, biomedical, environmental and territorial Sciences” of University of Molise.
From 2013 Vice-president of Nursing Course of Dept of Medicine and Health Sciences of
University of Molise.
Skills
Fluent in speaking and writing English.
Good practical knowledge of:
- Operative Systems: MS-DOS, WINDOWS, UNIX, LINUX
- Statistic Programs: SPSS, PRISM
- Softwares: WORD, EXCEL, ACAD, MATHEMATICA, DBASE, POWERPOINT, MAKER
PRO, GEL-DOC, OPEN OFFICE
Good theoretical and practical knowledge in molecular biology (Western Blot, in vivo
experiments, immunoprecipitation, using bioinformatic systems, organs isolation, PCR)
and techniques of physical training on laboratory animals.
Publications in
international journals
Ferrara N, Komici K, Corbi G, Pagano G, Furgi G, Rengo C, Femminella GD, Leosco D,
Bonaduce D. β-adrenergic receptor responsiveness in aging heart and clinical implications.
Front Physiol. 2014;4:396.
Corbi G, Conti V, Russomanno G, Longobardi G, Furgi G, Filippelli A, Ferrara N.Adrenergic
signaling and oxidative stress: a role for sirtuins? Front Physiol. 2013;4:324. doi:
10.3389/fphys.2013.00324.
Conti V, Russomanno G, Corbi G, Izzo V, Vecchione C, Filippelli A. Adrenoreceptors and
nitric oxide in the cardiovascular system. Front Physiol. 2013;4:321.
Bianco A, Mazzarella G, Turchiarelli V, Nigro E, Corbi G, Scudiero O, Sofia M, Daniele A.
Adiponectin: an attractive marker for metabolic disorders in Chronic Obstructive Pulmonary
Disease (COPD). Nutrients. 2013;5(10):4115-25. doi: 10.3390/nu5104115.
Corbi G, Bianco A, Turchiarelli V, Cellurale M, Fatica F, Daniele A, Mazzarella G, Ferrara N.
Potential Mechanisms Linking Atherosclerosis and Increased Cardiovascular Risk in
COPD: Focus On Sirtuins. Int J Mol Sci. 2013;14(6):12696-713. doi:
10.3390/ijms140612696.
Braido F, Comaschi M, Valle I, Delgado L, Coccini A, Guerreras P, Stagi E, Canonica GW;
ARGA Study Group; EAACI/CME Committee. Knowledge and health care resource
allocation: CME/CPD course guidelines-based efficacy. Eur Ann Allergy Clin Immunol.
2012;44(5):193-9.
Conti V, Russomanno G, Corbi G, Guerra G, Grasso C, Filippelli W, Paribello V, Ferrara N,
Filippelli A. Aerobic training workload affects human endothelial cells redox homeostasis.
Med Sci Sports Exerc. 2013;45(4):644-53. doi: 10.1249/MSS.0b013e318279fb59.
Corbi G, Conti V, Russomanno G, Rengo G, Vitulli P, Ciccarelli AL, Filippelli A, Ferrara N. Is
physical activity able to modify oxidative damage in cardiovascular aging? Oxid Med Cell
Longev. 2012;2012:728547. doi: 10.1155/2012/728547.
Maio S, Baldacci S, Simoni M, Angino A, Martini F, Cerrai S, Sarno G, Pala A, Bresciani M,
Paggiaro P, Viegi G; ARGA Study Group. Impact of asthma and comorbid allergic rhinitis
on quality of life and control in patients of Italian general practitioners. J Asthma.
2012;49(8):854-61.
Corbi G, Grattagliano I, Catanesi R, Ferrara N, Yorston G, Campobasso CP. Elderly
residents at risk for being victims or offenders. J Am Med Dir Assoc. 2012;13(7):657-9. doi:
10.1016/j.jamda.2012.05.012.
Conti V, Russomanno G, Corbi G, Filippelli A. Exercise training in aging and diseases.
Transl Med UniSa. 2012;3:74-80.
Baldacci S, Maio S, Simoni M, Cerrai S, Sarno G, Silvi P, Di Pede F, Borbotti M, Pala AP,
Bresciani M, Viegi G; ARGA study group. The ARGA study with general practitioners:
impact of medical education on asthma/rhinitis management. Respir Med.
2012;106(6):777-85. doi: 10.1016/j.rmed.2012.02.013.
Corbi G, Conti V, Scapagnini G, Filippelli A, Ferrara N. Role of sirtuins, calorie restriction
and physical activity in aging. Front Biosci (Elite Ed). 2012;4:768-78.
Conti V, Corbi G, Russomanno G, Simeon V, Ferrara N, Filippelli W, Limongelli F, Canonico
R, Grasso C, Stiuso P, Dicitore A, Filippelli A. Oxidative stress effects on endothelial cells
treated with different athletes' sera. Med Sci Sports Exerc. 2012;44(1):39-49. doi:
10.1249/MSS.0b013e318227f69c.
D'Addio G, Cesarelli M, Corbi G, Romano M, Furgi G, Ferrara N, Rengo F. Reproducibility
of heart rate turbulence indexes in heart failure patients. Conf Proc IEEE Eng Med Biol
Soc. 2010;2010:2573-6. doi: 10.1109/IEMBS.2010.5626653.
Rengo G, Leosco D, Zincarelli C, Marchese M, Corbi G, Liccardo D, Filippelli A, Ferrara N,
Lisanti MP, Koch WJ, Lymperopoulos A. Adrenal GRK2 lowering is an underlying
mechanism for the beneficial sympathetic effects of exercise training in heart failure. Am J
Physiol Heart Circ Physiol. 2010 Jun;298(6):H2032-8. doi: 10.1152/ajpheart.00702.2009.
D'Addio G, Corbi G, Accardo A, Russo G, Ferrara N, Mazzoleni MC, Princi T. Fractal
behaviour of heart rate variability reflects severity in stroke patients. Stud Health Technol
Inform. 2009;150:794-8.
Porta A, D'Addio G, Corbi G, Maestri R, Pinna GD. Circadian variations of short-term heart
period irreversibility in healthy and chronic heart failure patients. Conf Proc IEEE Eng Med
Biol Soc. 2008;2008:2116-9. doi: 10.1109/IEMBS.2008.4649611.
Ferrara N, Corbi G, Capuano A, Filippelli A, Rossi F. Memantine-induced hepatitis with
cholestasis in a very elderly patient. Ann Intern Med. 2008 Apr 15;148(8):631-2.
Corbi G, Acanfora D, Iannuzzi GL, Longobardi G, Cacciatore F, Furgi G, Filippelli A, Rengo
G, Leosco D, Ferrara N. Hypermagnesemia predicts mortality in elderly with congestive
heart disease: relationship with laxative and antacid use. Rejuvenation Res.
2008;11(1):129-38. doi: 10.1089/rej.2007.0583.
Ferrara N, Rinaldi B, Corbi G, Conti V, Stiuso P, Boccuti S, Rengo G, Rossi F, Filippelli A.
Exercise training promotes SIRT1 activity in aged rats. Rejuvenation Res. 2008;11(1):13950.
Longobardi G, Corbi G, Cacciatore F, Abete P, Furgi G, Vitale DF, Rengo F, Ferrara N.
Effect of losartan in treatment of exercise-induced myocardial ischemia. Am J Cardiol.
2007;100(10):1517-21.
Lubrano E, D'Angelo S, Parsons WJ, Corbi G, Ferrara N, Rengo F, Olivieri I. Effectiveness
of rehabilitation in active ankylosing spondylitis assessed by the ASAS response criteria.
Rheumatology (Oxford). 2007;46(11):1672-5.
Rinaldi B, Corbi G, Boccuti S, Filippelli W, Rengo G, Leosco D, Rossi F, Filippelli A, Ferrara
N. Exercise training affects age-induced changes in SOD and heat shock protein
expression in rat heart. Exp Gerontol. 2006;41(8):764-70.
Ferrara N, Corbi G, Bosimini E, Cobelli F, Furgi G, Giannuzzi P, Giordano A, Pedretti R,
Scrutinio D, Rengo F. Cardiac rehabilitation in the elderly: patient selection and outcomes.
Am J Geriatr Cardiol. 2006;15(1):22-7.
Ferrara N, Abete P, Corbi G, Paolisso G, Longobardi G, Calabrese C, Cacciatore F, Scarpa
D, Iaccarino G, Trimarco B, Leosco D, Rengo F. Insulin-induced changes in betaadrenergic response: an experimental study in the isolated rat papillary muscle. Am J
Hypertens. 2005;18(3):348-53.
Longobardi G, Ferrara N, Leosco D, Abete P, Furgi G, Cacciatore F, Corbi G, Pescatore R,
Rengo F. Angiotensin II-receptor antagonist losartan does not prevent nitroglycerin
tolerance in patients with coronary artery disease. Cardiovasc Drugs Ther. 2004;18(5):36370.
Corbi GM, Carbone S, Ziccardi P, Giugliano G, Marfella R, Nappo F, Paolisso G, Esposito
K, Giugliano D. FFAs and QT intervals in obese women with visceral adiposity: effects of
sustained weight loss over 1 year. J Clin Endocrinol Metab. 2002;87(5):2080-3.
Book Chapters
- Modificazioni della risposta β-adrenergica indotte dall’insulina. Studio sperimentale. Voza
M, Fiore G, Ziello V, Puzio G, Corbi G, Scoti G, Ferrara N, Varrichio M. In: Rendiconti ed
atti dell’accademia di scienze mediche e chirurgiche di D’Onofrio F. Virg En vi, 730 ed,
Napoli 2003, pp 97-104. ISSN: 0370-7369
- Stress ossidativo ed insufficienza cardiaca. N. Ferrara, G. Corbi, A. Filippelli In: Lo
scompenso Cardiaco dai meccanismi molecolari al razionale delle nuove strategie di
approccio clinico-terapeutico. di F. Rengo , M. Chiariello, D. Leosco, M.W. Rich. Critical
Medicine Publishing, 2004, pp 157-64. ISBN CMP018
- Quantitative Poincarè plots analysis contains relevant information related to heart rate
variability dynamics of normal and pathological subjects. D'addio G, Pinna Gd, Maestri R,
Corbi G., Ferrara N, Rengo F. (2004). In: Computers in Cardiology. (vol. 31, pp. 457-460).
CHICAGO: IEEE Computer Society Press (UNITED STATES) ISBN: 0-7803-8927-1.
- Dall’unitarietà alla molteplicità del quadro morboso. Ferrara N, Corbi G, Longobardi G,
Cacciatore F, Rengo F. In: Le basi culturali della Geriatria di Società Italiana di Geriatria e
Gerontologia Tipografia Cooperate ed, Roma, 2005, pp 59-66.
- Le polmoniti in età geriatrica. N. Ferrara, S. Fuschillo, G. Corbi, F. Rengo. In: Contempo
2005: Le malattie dell’anziano Accademia Nazionale di Medicina - Società Italiana di
Gerontologia e Geriatria. CIC Edizioni Internazionali eds, Roma, 2005, pp 69-75. ISBN:
88-7141-698-8
- Poincare' plot analysis of Heart Rate Variability in stroke patients. D'addio G, Corbi G.,
Rengo G, Russo G, Pinna GD, Maestri R, Ferrara N, Rengo F. (2006). In: 3rd European
Medical and Biological Engineering Conference. (vol. 11, pp. 45-51). ROMA: EMBEC'05
ISBN: 3-901351-62-0
- I beta bloccanti nel paziente diabetico con insufficienza cardiaca. Ferrara N, Corbi G.,
Marchese M, De Lisa G, Zincarelli C, Cacciatore F, Longobardi G, Filippelli A. In: I nuovi
beta-bloccanti nell'insufficienza cardiaca: il paziente difficile di Rengo F., Leosco D. Critical
Medicine Publishing Editore, ROMA, 2006: pp. 71-81. ISBN: 88-88415-21-1.
- La prevenzione cardiovascolare nell'anziano. Ferrara N, Corbi G., Cacciatore F, Rengo
G, Longobardi G, Rengo F.. In: L'anziano affetto da scompenso cardiaco: la prospettiva
multidimensionale di Bianchetti A., Rozzini R., Trabucchi M. ROMA: Critical Medicine
Publishing Editor 2006: pp. 45-66. ISBN: 88-88415-33-5.
- Effects of Stroke Localization on Nonlinear Indexes of HRV.D'addio G, Accardo A, Corbi
G., Russo G, Pinna GD, Ferrara N, Rengo F. (2006). In: Computers in Cardiology. (vol. 33,
pp. 621-624). CHICAGO: IEE Computer Society in Press (UNITED STATES). ISBN: 07803-8927-1.
- Fractal analysis of heart rate variability in COPD patients Accardo A, D’Addio G, Corbi G,
Ferrara N, Rengo F. IFMBE Proceedings ISSN 1680-0737 Volume 16 in Book 11th
Mediterranean Conference on Medical and Biomedical Engineering and Computing 2007.
Publisher Springer Berlin Heidelberg .DOI 10.1007/978-3-540-73044-6. ISBN 978-3-54073043-9 (Print) 978-3-540-73044-6 (Online); pp 78-81
- Fractal Analysis Of Heart Rate Variability Dynamics Of Normal And Pathological
Subjects. D’Addio G, Accardo A, Corbi G, Ferrara N, Rengo F. Biosignal 2008 Proceedings
pp. 136-140 ISSN 1211-412X ISBN 978-80-214-3612-1
- Circadian variations of short-term heart period irreversibility in healthy and chronic heart
failure patients. Porta A, D'Addio G, Corbi G, Maestri R, Pinna GD. Conf Proc IEEE Eng
Med Biol Soc. 2008;2008:2116-9.
- Fractal behaviour of pathological heart rate variability dynamics. G. D’Addio, A. Accardo,
G. Corbi,, F. Rengo, N. Ferrara Modelling in Medicine and Biology VIII Edited By: C.A.
BREBBIA, Wessex Institute of Technology, UK Volume: 13 (2009) - ISBN: 978-1-84564183-2 ; ISSN:1743-3525 (on line) ISSN: 1747-4485 (print) ppgg 39-47
- Fractal behaviour of heart rate variability reflects severity in stroke patients. D'Addio G,
Corbi G, Accardo A, Russo G, Ferrara N, Mazzoleni MC, Princi T. Proceedings of MIE
2009 – The XXIInd International Congress of the European Federation for Medical
Informatics Edited by Klaus-Peter Adlassnig, Bernd Blobel, John Mantas, Izet Masic pp:
794-798
- Correlation between fractal behavior of HRV and neurohormonal and functional indexes
in chronic heart failure. D’ Addio G, Cesarelli M, Romano M, Accardo A, Corbi G, Maestri
R, La Rovere MT, Bifulco P, Ferrara N, Rengo F: Proceed. XII Mediterranean Conference
on Medical and Biological Engineering and Computing, MEDICON 2010, 27-30 May 2010,
Porto Carras, Chalkidiki, Greece IFMBE Proceed. Bamidis-Pallikarakis Eds, Springer,
Vol.29 pp. 53-56 ISSN 1680-0737 ISBN 978-3-642-13038-0
Other
Referee for:
BioMedical Central
Free Radical and Biology Journal,
Frontiers in Physiology
Journal of American Aging Association
Journal of Nutrition,
Journal of Pharmaceutics & Pharmacology and
IEE Conference since 2009 to date.
Reviewer of the Italian Ministry of University and Research.
Member of the Editorial Board for the
World Journal of Translational Medicine and
Journal of Geriatric Cardiology
Affiliation to SIGG (Italian Society of Gerontology and Geriatrics), and SINU (Italian Society
of Human Nutrition)
Grant for the best oral presentation at 47° National Congress of Italian Society of
Gerontology and Geriatrics
Grant for the best oral presentation at 50° National Congress of Italian Society of
Gerontology and Geriatrics
Grant for the best oral presentation at 8° National Congress of GICR (Italian Groupoof
rehabilitative end preventive Cardiology)
Grant for the best oral presentation at 35° National Congress of Italian Society of
Pharmacology
Participation as speaker to several national and International Congresses
Invited lecture to the ESC Congress 2014 (Barcelona – Spain- 30 August to 03 September
2014) on “Novel aspects of beta adrenoceptor kinetics”
keywords
Sirtuins and physical activity, sirtuins and physical activity in aging,
gender medicine in elderly, elderly abuse.
Campobasso, 04.02.2014
Graziamaria Corbi