PDLS©: Children in Disaster: Public Health Considerations and Disaster Mitigation QuickTime™ and a decompressor are needed to see this picture. Preparing for the Public Health consequences of disaster involving children should occur at the Community, State and Federal levels. The benefits of this type of planning have been proven many times over Objectives Identify personnel, equipment and infrastructure for pediatric disaster preparedness • • Learn the principles of family disaster planning • Recognize which potential biological disasters may be mitigated by public health measures • Consider public health implications of chemical and radiation attacks • Understand the components of disaster mitigation Community Resources Pediatric emergency and trauma centers Pre-hospital care providers, including EMS, fire departments and police Social services Schools Local health clinics Departments of Health Government Local and national media Photo Courtesy of FEMA Emergency Medical Services for Children (EMS-C) in a Disaster A program of Health Resources and Services Administration (HRSA) - Education and grant funding for development pre-hospital pediatric care Provides designations for pediatric disaster centers - Emergency Department Approved for Pediatrics (EDAP) Pediatric Critical Care Center (PCCC) Stand-by Emergency Department Approved for Pediatrics (SEDP) Plans for Surge Capacity Facilities Hospitals without formal pediatrics services Community health centers Rehabilitation hospitals Urgent care centers Physicians’ offices Nursing homes School-based health centers Field hospitals in gymnasiums, warehouses, arenas and convention centers Religious or faith-based facilities Healthcare Providers Coursework Available coursework for pediatric clinician disaster preparedness: Basic and Advanced Disaster Life Support (BDLS, ADLS) Disaster Preparedness for School Nurses Pediatric Advanced Life Support (PALS) Advanced Pediatric Life Support (APLS) Emergency Nursing Pediatric Course (ENPC) Pediatric Education for Pre-hospital Professionals (PEPP) Advanced Trauma Life Support (ATLS) Equipment Necessary for Pediatric Disaster Preparedness Airway equipment IV access devices ( intravenous lines, intraosseous needles) Warming blankets Radiant warmers Normal saline Pediatric nutrition supplies - Formula, G-tube feeds, Child-friendly non-perishable items Laryngeal Mask Airway Vectors of Transmission of Infectious Diseases Affected by Disaster Airborne - Crowded habitation Waterborne - Contaminated water supply Children most susceptible Foodborne - Problems with proper storage Insect and Animal borne - Decrease disease transmission control Consider the Needs of Children in Family Preparedness Planning Listing of key phone numbers Create an emergency kit - Prescription medications OTC medications Formula/Food Diapers Clothes Create a list of trusted adults and a safety “password” Comfort objects and foods Family Disaster Planning (focus on the safety of the children): Safe sites within the home Family communication – reassembly plan (children at school parents at work) Stored disaster supplies (water, food, cooking equipment, heat sources) Conduct drills for common disasters (tornado, earthquake) In reality few families have done any planning Pets in Disaster Planning Case study-Katrina QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. Family Disaster Planning Preparation: Home Create and discuss disaster plan for family Acquaint all family members with first aid equipment in home Route of egress from home Meeting place outside Conduct drills Preparation: Home Keep disaster stores of food, meds, diapers, etc. Have “disaster containers” in home and car Special needs children - Early evacuation plans, etc Pharmaceutical/Medical Supply Stockpiles The Centers for Disease Control and Prevention (CDC) provide a Strategic National Stockpile (SNS) - Developed in 1999 for anthrax Point of delivery (POD) system for local distribution, with supplementation by state and national sources within 48 hours States should plan on being self-sufficient for 72 hours before SNS arrives Instructions for accessing PODS - Use of United States Postal Service for distribution Security considerations Available media used to disseminate distribution point locations Pre-event Public Health Planning Issues: Evacuation of populations at risk. Provide temporary shelter and protection from the environment. Provide food, water and clothing. Plan for adequate personnel hygiene (toilets, showers, etc.). Backup plans for communications, transportation and activities for children. Plan for management of children with special needs. Post-event Public Health Response Issues: Finding and extracting individuals who refused to evacuate Manage neglected chronic medical issues (diabetes, heart disease, etc.) Provide for medical emergencies and childbirth Keeping confined children healthy (medical & psychological). Public Health Issues: Infectious Disease Outbreaks Type Examples • Airborne illnesses: Influenza, tuberculosis • Vector borne illnesses: Avian flu, malaria, dengue, tick related • Water-borne illnesses: (oral-fecal transmission) Cholera, salmonella, shigella, norovirus, cryptosporidiosis • Food borne illnesses: Fungi, E-Coli Influenza Influenza, a common viral respiratory virus with a long history of periodic pandemics Mutations in strains of influenza including bird flu pose risk of widespread outbreak Risk of death increases with secondary bacterial infections Highly contagious, spread via droplet and contact routes Influenza: Treatment and Prevention Amantadine is used for influenza A in children > 12 months - Useful if given within 2 days of symptoms Oseltamivir (Tamiflu) is approved for children > 12 months - Prevents release of viral particles - from infected cells Efficacious for influenza A and B Given orally bid for 5 days Both agents approved for chemotherapy, theoretically useful as prophylaxis Influenza: Treatment and Prevention Indications for immunoprophylaxis (protection from influenza A and B) - Children less than 9 years receiving influenza immunization for the first time require two doses one month apart The following children require immunization: - Persons aged 2-18 years with - comorbid conditions Children aged 6-59 months Pregnant adolescents Household contacts and out-ofhome caregivers of children aged <6 months Viral Hemorrhagic Fevers Viral hemorrhagic fevers, a group of diseases carried by animals and characterized by bleeding - More likely to be fatal in children Examples include Argentine Hemorrhagic Fever, Ebola, Lassa, Hanta and Nipah viruses Usually spread via contaminated body fluids, mosquitoes and ticks Rarely airborne Few antiviral drugs/chemotherapy available Mosquito and Tick Photos Credit: CDC Viral Hemorrhagic Fevers: Treatment and Prevention Most have no specific treatment Supportive care Two Exceptions - Argentine hemorrhagic fever convalescent serum - Ribavirin is an antiviral drug useful for Lassa virus Ribavirin Smallpox A delayed cutaneous infection spread via respiratory route Acute, contagious and sometimes fatal disease caused by the variola virus (an orthopoxvirus) Historically important disease - Speculation about availability as WMD Photos: CDC Photo Credit: CDC Smallpox: Treatment and Prevention Pre-exposure vaccination not currently recommended in children Vaccine is effective in decreasing disease severity within 4 days of exposure Ring vaccination strategy recommended in event of an outbreak Contraindications include eczema and immunodeficiency Vaccinia immune globulin (VIG) is immunotherapy stockpiled by CDC for complications of vaccine Edward Jenner Tularemia Tularemia, a disease of rabbits and rodents, spread to people by contact with these animals or the ticks and mosquitoes that feed on them Caused by Francisella tularensis - Can be aerosolized and used as a weapon - No immunization is widely available Tularemia: Treatment and Prevention Antibiotics - First line agents include gentamicin for 10 days - streptomycin and amikacin good alternatives - Doxycycline and fluoroquinolones are second line agents, with risk of adverse effects Doxycycline Brucellosis A disease usually caused by contact with infected animals and animal products Examples include cows and milk - Caused by Brucella bacteria - Can be aerosolized and used as a weapon - No immunization is widely available Brucellosis: Treatment and Prevention Indications for antibiotics - Recommendation for postexposure prophylaxis - Rifampicin and trimethoprimsulfamethoxazole (TMP-SMX) for 3-6 weeks - May be given by mouth - May use quinolones, doxycycline in children over 8 Plague Caused by Yersinia pestis, a bacterium found in rodents and their fleas in many areas around the world Forms: Bubonic, Septicemic and Pneumonic Can be aerosolized and used as a weapon Plague: Treatment and Prevention A plague vaccine is not currently available for use in the United States Antibiotics must be given within 24 hours of first symptoms Streptomycin 30 mg/kg/day divided in two doses Streptomycin Anthrax Anthrax, a disease of animal handlers and those who encounter contaminated animal products Inhalational most likely weapon - Used in 2001 anthrax mail contamination - Highly lethal - Initial flu-like illness for 2-5 days - Followed by intra-thoracic bleeding, dyspnea, pleural effusions and widened mediastinum Anthrax Delayed symptoms - Oral-gastrointestinal - Cutaneous - Hemorrhagic meningitis Lesion of Cutaneous Anthrax Associated With Microangiopathic Hemolytic Anemia and Coagulopathy in a 7-Month-Old infant Cutaneous Anthrax Pediatric case: - systemic illness seen transient DIC renal dysfunction - unique susceptibility? Anthrax Decontamination - Undress, soap/shower. Use 0.5% diluted household bleach for gross or visible contamination - Environment: 0.5% bleach Anthrax: Treatment and Prevention BioThrax immunization for animal handlers and military Limited data support intramuscular doses at 0, 2 and 4 weeks after exposure - - No human studies showing efficacy in post-exposure prophylaxis Prevents cutaneous anthrax in humans Animal studies show prevention of inhalation disease Not licensed by FDA for post-exposure prophylaxis Anthrax: Treatment and Prevention Initial prophylaxis with either fluoroquinolone or tetracycline - Ciprofloxacin (10-15 mg/kg/dose po q 12 hrs) not to exceed 1 gram per day or - Doxycycline - up to and including 8 years or over 8 years and less than or equal to 45 kg (2.2 mg/kg/dose po BID) Benefit of protecting children outweighs risks of medication exposure Once susceptibility of organism established, change to amoxicillin, clindamycin or vancomycin Treat for 60 days to allow time for spores to germinate and be killed Botulism Botulism, a paralytic disease caused by the toxin of Clostridium botulinum - Can be aerosolized and used as a weapon - Non-terrorist cases caused by contaminated food - No antibiotic/chemotherapy treatment exists Clostridium Botulinum Photo Credit: CDC Botulism: Treatment and Prevention Suspected cases require supportive care - Respiratory support Intravenous nutrition Botulinum antitoxin is available - Should be used in symptomatic cases before laboratory confirmation - Approved for use in children by FDA - Manufactured by California Department of Health Services Case Study – Rapid Displacement Rwandan Civil War – 1994 Disaster Type: Rapid displacement of a large improvished population (aka – complex humanitarian disaster) Medical Issues: Epidemics of infectious disease such as: cholera, hepatitis, exposure, nutritional needs of children Public Health Issues – Airborne Toxins Smothering construction materials, fuels, freon Examples: Silica, asbestos, h2g, CO, Lead, etc. Public Health Issues – Airborne Radiation Radiation Exposure “In some respects, major radiation exposure due to a terrorist attack should be easier to manage than chemical or biological attacks. An important resource is the tens of thousands of persons who deal with radiation daily at hospitals, universities, military units, national laboratories, and government agencies”. NEJM 2002 Radiation Characteristics Type Penetrate Comments Alpha No Beta Superficial Gamma Deep Inhale, ingest, open wound Electrons, a few centimeters Easy penetration X-Ray Deep Easy penetration Severity None Death ED MD Response Seal ED with police-security Get Radiation Safety to ED STAT Create decontamination area Outside Don’t Contaminate ED Wear gowns, gloves, radiation detectors Public Health Issues – Personal & Intrapersonal Violence and Abuse Child abuse, PTSD, partner abuse, suicide, substance abuse What is Disaster Mitigation? Steps taken prior to and after a disaster to minimize morbidity and mortality Examples include: - disaster plans: community, school, and home - pre-designated shelters - clean water stores, food stores - post disaster emotional support Examples of Disaster Mitigation Activities: Community wide influenza vaccination programs Enforcement of engineering codes for construction projects Avoidance of construction in disaster prone areas Stockpiling of supplies in safe places Disaster Mitigation: Planning for Mass Gathering (particularly those involving children): Concerns: fire, riot-stampede, major accidents (stage collapse), inclement weather Specifics: onsite EMS deployment; triage plan from site to available medical facilities Preparation: School Makes disaster plan known to all Routes of egress from school Meeting place Drills Hospital Interface Work with local and state officials to create disaster management plan Local EMS plans for all schools & daycares Practice interface between school, EMS, and hospital with drills at least once a year Recovery Phase: Initial Shelters should be “kid friendly” Keep families together Personnel to organize area for orphaned and separated children until families reunited Create children's groups in shelter, plenty of toys, books, etc.. Recovery Phase: Long-term Psychological services early Be attentive to children's needs, consider educational resources for long-term sheltering. Aberrant behavior may be manifestation of emotional trauma Recovery Phase: Long-term Children must feel safe in home, community and school; encourage this Learn from mistakes Disaster Mitigation: What you can do Emergency physicians, Pediatric EM physicians, Pediatricians, Nurses, other health care professionals: - Preparation before disaster - Action during disaster - Recovery phase Before Disaster Strikes Involve yourself in the local EMS and area disaster plan: help to develop systems that keep children's’ needs in mind Work with schools, daycares and local hospitals to develop integrated disaster plans Act as an advisor to your patients for home disaster planning Before Disaster Strikes Arrange disaster response drills Promote community awareness addressing pediatric needs During A Disaster Be active!! Institute disaster plans in your facility Participate in the community response to disaster Disaster Recovery Provide medical care to shelters Assume basic community services will be disrupted for some time Attend to emotional needs of the pediatric population effected Summary Pediatric disaster public health issues require the right people, places, tools and plans Disaster preparedness includes planning, training, and acquisition of appropriate medications and equipment Photo Credit: FEMA Disaster mitigation begins before the event