Somvilai Mayurasakorn, MD. Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University Helical Tomotherapy Tomotherapy Planning Parameters • Smaller field widths, smaller pitches and higher modulation factors More conformal plans But increased treatment time !! Helical Tomotherapy Image acquisition and matching • MVCT fan-beam images • In-plane resolution of 0.78 mm at the bore center ; mean beam energy = 0.75 MeV • Set up slices thickness of 2, 4 or 6 mm – ‘fine’, ‘normal’ and ‘coarse’ settings • The scan length is kept as short as possible – always within the region of the PTV Helical Tomotherapy Image matching Dept. of Radiation Oncology M.D. Anderson Cancer Center Orlando Dept. of Radiation Oncology M.D. Anderson Cancer Center Orlando Helical Tomotherapy Dept. of Radiation Oncology M.D. Anderson Cancer Center Orlando Helical Tomotherapy Palma et al. Cancer Treatment Reviews 2010;36 :393–399 Helical Tomotherapy Helical Tomotherapy Helical Tomotherapy Helical Tomotherapy Conclusions • Combination of IGRT and IMRT • Use ARC therapy : all angles are available to deliver radiation to target • Treatment field length up to 160 cm • More conformal and homogeneity while sparing of OARs than IMRT Helical Tomotherapy • Successful implementation of Tomotherapy Careful planning and effective teamwork Daily image guidance Positional correction Intensity-modulated delivery Tomotherapy Treatment Centers : Asia-Pacific • South Korea – Incheon St. Mary’s Hospital, Catholic Medical Center – KangNam St Mary’s Hospital, Catholic University Hospital – Yonsei Cancer Center, Severance Hospital (2) – GangNam Severance Hospital – National Cancer Center – Catholic Medical Center, St.Vincent’s Hospital – Yongdong Severance Hospital – Samsung Medical Center – KyungHee University Medical Center – Korea University Anam Hospital • China – PLA General Hospital , Beijing – Airforce Hospital, Beijing – Beijing PLA General Hospital – Chung Shan Hosp , Shanghai • Hong Kong – Hong Kong Sanatorium and Hospital – Queen Elizabeth Hosp Tomotherapy Treatment Centers in Asia-Pacific • Taiwan – – – – – – – • • Tata Memorial Hospital, Delhi Tata Memorial Hospital, Calcutta AIIMS, Delhi Indo American Hospital, Bangalore Singapore – – Mount Elizabeth Hospital National Cancer Center Malaysia – – Prince Court Medical Center Sime Darby Medical Center Japan – – – – – – – – – – – – – – – National Taiwan University Hospital China Medical University Hospital Shin Kong Wu Ho-Su Memorial Hospital Yuan General Hospital Far Eastern Memorial Hospital(2) Chung Shan Medical University Hospital Kaoshiung Hospital India – – – – • • Clinic – C4 Chiba Fukui Prefecture Saiseikai Hosp Fukui Saiseikai Hosp Fukushima Medical Centerl Towada City Hospital Koga Hospital 21 Aizawa Hospital Saiseikai Kumamoto Hospital Takeda Hospital Nagoya Daini Red Cross Hospital Kizawa Memorial Hospital Hokuto Hospital Hidaka Hospital Edogawa Hospital Aichi Cancer Center Hospital and Research Institute • Thailand – Chiang Mai University Hosp • Australia – Royal Brisbane & Women’s Hospital Quality Depends on Number of Beams COMING SOON 1 Beam 5 Beams 11 Beams 17 Beams 25 Beams 51 Beams Helical Tomotherapy Dose distribution for one patient of regular delivery A. 2.5-cm-field width (REG 2.5) B. 5-cm-field width (REG 5) doses are shown in Gy STERZING et al. Int. J. Radiation Oncology Biol. Phys. 2010;76 (4):1266–1273 Helical Tomotherapy • A modulation factor of 2 or 3 is usual • For relatively simple cases, such as the prostate alone, a value of 2 is normally sufficient • For cases with more complex, intricate shapes, such as HNC, a modulation factor of 3 is usually selected University of Cambridge /Burnet et al. Clinical Oncology 2010;22:294–312 Gross Tumor Volume (GTV) GTV contour definition GTV1 The primary tumor (GTV 1) A 1 cm peripherally enhancing lymph node (GTV2) GTV2