Demographics of Aging and Geriatric Syndromes

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Gerry Gleich M. D.

Geriatrics Interclerkship

April 26, 2013

13% of the U.S. population is currently over

65

By 2030 it is expected there will be 68 million

Americans older than 65 or 20% of the population

In 1900 life expectancy was 47.3 years

By 1950 life expectancy was up to 68.2 years

2010 life expectancy was 78.7 years

 Older women outnumber older men at 23.0 million older women to 17.5 million older men.

 Current life expectancy for women is 81.1 years for men it is 76.2 years

At age 65 life expectancy is about 19 more years

At age 75 life expectancy is about 12 more years

At age 85 life expectancy is about 7 more years

The geriatric population is becoming more ethnically diverse in the U.S.

Currently the non-hispanic white are 73.6 % of the elderly but expected to decline to

60.5% by the year 2030

Increases in the Hispanic-American and

Asian-American populations are expected

In the community 75% of men over 65 are likely to be married and living with their spouse

41% of women over 65 are married and living with their spouse

47% of women over 65 are widows

13% of men over 65 are widowers

Likelihood of living alone increases with aging

Options for living

 Independent with or without assistance

 Retirement communities

 Group settings

 Foster care

 Assisted living

 Long-term care

Patient needs Resources

ADLs

IADLs

Physical

Emotional

Spiritual

Spouse/Family

Friends

Community

Church

Financial

Own home or apartment

Congregate or senior housing may have: help with some household upkeep congregate meals activities

 staff specific home health services available through outside agencies

Naturally Occurring Retirement Communities (NORC)

 “A type of living arrangement in which personal care services such as meals, housekeeping, transportation, and assistance with ADLs are available as needed to people who still live on their own in a residential facility”

▪ Center for Medicare and Medicaid Services

2007

975,000 residents

38,000 facilities (25-120 units)

2009

$3022/mo ave cost for pvt unit

($10K-$50K/yr range)

Assisted Living Facilities of America

National Center for Assisted Living

Most Assisted Living Facilities will provide:

 Health care management and monitoring

 Help with activities of daily living such as bathing, dressing, and eating

 Housekeeping and laundry

 Medication reminders and/or help with medications

 Recreational and social activities

 Security

 Transportation

 Emergency call system in each unit

 Half the price of a nursing home, but what services are you getting?

 Liability is hurting development of the industry

 Much less regulation than nursing homes right now

 Aging in place is a big issue

2010

15,622 facilities (MA 429)

1.66 million beds (MA 48,484)

1.4 million residents

Av LOS 875 days

Av cost $198/day

(Alaska $687, MA $329)

%≥65 yo in NH?

www.longtermcare.gov

www.statehealthfacts.org

 Abuse in 1960s, 1970s led to

 Reforms in 1980s (OBRA ’87) led to

 Government regulation

 How is it changing?

 Can we make it a more positive alternative?

 Resident-centered care

Expanding access to insurance

Reducing administrative costs

Payment reform

Incentivize Electronic Health Records

Incentivize prevention and primary care

Accountable Care Organizations

Bundled payments

Payment for quality of care

Improvements in Prescription Drug benefits

Premium increases for more wealthy seniors

Preventive services covered

Respond to Changing Demographics and

Economics

Improve quality of life and care

Minimize morbidity

Maximize function

Normal age-related changes vs. pathologic

Biopsychosocial model of care

Patient-centered Goal-Oriented Care

Age is not an accurate predictor of condition or function

Co-morbidities are common

Presentation of illness is altered (nonspecific)

Homeostatic control is less efficient

Less functional reserve. A Chain is only as strong as its weakest link

Medical

Cognitive

Polypharmacy

Nutrition Functional Decline Social support

Incontinence

Environmental

Special senses

The single best predictor of institutionalization is impaired functional status

Self-reported function is an accurate predictor of health risks and costs

23% of older adults report some functional limitation in either ADLs or IADLs much higher percentage for the oldest segments

Functional Status at Age 70

Life Expectancy

(in years)

Annual Health

Care Costs

Independent

IADL Deficit Only

14.3

12.4

$4,600

$8,500

1 + ADL Deficit

Lubitz. NEJM 2003; 349:1048-55

11.6

$14,000

Bathing

Dressing

Transferring

Toileting

Grooming

Feeding

Mobility

Telephone

Meal preparation

Managing finances

Taking medications

Doing laundry

Doing housework

Shopping

Managing transportation

Common presenting complaints should make alarms sound in your head to think comprehensively.

These presenting complaints are likely to have multifactorial causes including the effects of agerelated changes and chronic disease mediated changes

 Frailty and failure to thrive

Dizziness

Syncope

Osteoporosis

Falls

Malnutrition

Urinary incontinence

Pressure ulcers

Dementia

Delirium

Polypharmacy

More on some of these syndromes…

Visual impairment

Hearing impairment

Incidence is about 20% of those older than 65 and 50% of those older than 75

90% success with surgery (vision improved to at least 20/40)

Surgery is safe taking less than 30 minutes: breakdown of old lens, and new lens implant

About 15% of patients need addition laser capsulotomy after lens implant

 Central vision is affected

Affects 10% of adults over age 65 and 25% over age 75

Can contribute to social isolation, anger, depression, family arguments

Cerumen drier and thicker

Tympanic membrane thicker

Ossicular joints degenerate

Cochlear changes

 loss of hair cells

 stiffening of basilar membrane

 neuronal loss

Decreased central auditory processing

Ask the listener preferred way to communicate with them

Obtain listener’s attention before speaking

Eliminate background noise

Make sure the listener can see your lips

Speak slowly and clearly avoid shouting

Speak to the better ear

Change phrasing if listener doesn’t seem to understand

Spell, use gestures or write down words

Ask the listener to repeat what they heard

Complications of falls are the leading cause of death from injury in adults over age 65

33% of adults over age 65 report falling within the past year

Most result in minor soft tissue injuries

10-15% result in fractures

5% result in more serious soft tissue injury or head trauma

Cost is considerable – ED visits, admission surgery etc.

Age related changes

Disease related effects

Medication effects

Environmental

Visual decline

Vestibular loss of hair cells, ganglion cells

Postural control declines

Muscle mass declines

Baroreceptor and autonomic nervous system efficiency decline

Acute systemic illness

Parkinson’s

CVA

Osteoarthritis

Neuropathy

Visual impairments

 Psychotropic Medications

 Benzodiazepines

 SSRIs

 Antipsychotics

Cardiac – orthostatic hypotension

Hypoglycemic agents

Anticholinergics

Minimize medications

Prescribe exercise strength training

Treat visual impairments

Manage postural hypotension

Supplement Vitamin D 800IU/day

Manage foot and footwear issues

Assistive devices and supervision as needed

Modify home environment

Affects 6-8% over age 65 and 30% over age 85

As baby boomers age this will be more and more common

Risk factors: Age, Family History, Down’s Syndrome,

Head trauma, Fewer years of education, CV risk factors

Patients with mild cognitive impairment progress to

Alzheimer’s at a rate of 12% per year

Alzheimer’s Disease –Gradual Progression 8-10 years, memory, language, visuospatial, and later apraxia

Vascular Dementia –Step-wise progression related to small vessel disease

Lewy Body Dementia- Gradual progression with

Parkinson’s symptoms and hallucinations

Frontotemporal Dementia-may be more rapid and presenting with disinhibition

Maximize function

Assess goals and advance directives early

Assess caregiver resources, understanding, and stress

 Assess contribution of other medical conditions, environment and medications to overall picture

Could delirium or depression be present

Metabolic profile

Selective use of imaging

 Onset at a young age <65

 Sudden onset

 Focal neurologic findings

 Normal Pressure Hydrocephalus suspicion

 Recent fall or head trauma

Support function

Physical activity

Family and caregiver education and support

Environmental modification

Attention to safety

Advance directives

Medications

 May slow decline

 Can manage behavioral symptoms

Affects 15-30% of adults over age 65

Affects 60-70% of long term care residents

Can lead to cellulitis, ulcerations, social isolation, falls, institutionalization

Improvements can be made with an organized approach

Urge

 Detrusor hyperactivity

Stress

 Pelvic floor relaxation and increased intra-abdominal pressure

Mixed

Incomplete emptying

 Dilated bladder with impaired contractility may also have detrusor hyperactivity with impaired contractility

Multifactorial

Assess comorbidities, functional status and medication effects

U/A for hematuria and pyuria

No routine culture. Positive culture may reflect asymptomatic bacteriuria

Consider post void residual

 PVR >300 should lead to assessment of renal function and urology referral within 2 months

 PVR 200-300 evaluate renal function within 3 months

 PVR <200 maximize overall medical status

Behavioral

 Incontinence supplies

Surgical

Pharmacologic

Catheters

 Extremely common in community dwelling older adults

 Difficulty falling asleep 40%

 Nighttime awakening 30%

 Early morning awakening 20%

 Daytime sleepiness 20%

 At least one half of community dwelling older adults use OTC or prescription sleep medications

Total sleep time decreases

Time to fall asleep (latency) increase or no change

Sleep efficiency decreases

Daytime napping increases

Percent REM sleep decreases

Wake after sleep onset increases

 30-60% associated with psychiatric disorders

(depression, anxiety)

Pain

GE Reflux

Nocturia

Periodic Limb Movements

Sleep related breathing disorders

Dementia

Medication effects

 Sleep hygiene measures

 Regular times for sleep

 Bed for sleep only

 Exercise daily

 Relax before bed

 Limit food intake, stimulants, alcohol before bed

 Dark quiet environment, comfortable temperature for sleep

 Exposure to bright light during the day

 Behavioral techniques to emphasize sleep hygiene

 Relaxation techniques

 Cognitive interventions

 Bright light therapy to correct circadian rhythm disturbance

Try non-pharmacologic measures

Avoid benzodiazepines

 Associated with falls

 Rebound insomnia

Sedation into the daytime

 Tolerance and withdrawal syndrome

Short acting nonbenzodiazepine-benzodiazepine receptor agonists NBRA’s

(zaleplon, zolpidem, eszopiclone)

Rapid onset take right before bed

 No rebound

 Only use 2-3 nights per week

Sedating antidepressants (mirtazapine, trazodone) for patients with depression

OTC Sleep Agents

 Avoid antihistamines - anticholinergic effects

 Melatonin – may be helpful

 Valerian no good evidence of efficacy

 Kava – risk of hepatotoxicity

The elderly account for 33% of drug costs in the U.S.

The average elderly person is on 4.5 prescription drugs and 3.5 OTC drugs at any given time

The risk of an adverse drug reaction is proportional to the number of drugs a person is taking

“Any new symptom should be considered a drug side effect until proven otherwise”

Reconcile medications at each visit

Stop unnecessary medications

Weigh risk vs. benefit for any new med

Consider the big picture - functional status

Monitor for adverse effects

Avoid the prescribing cascade

Goals change as overall level of function and health changes

Knowledge of natural history of diseases is important in helping to prognosticate

Knowledge of functional status is even more important

Keep the big picture in focus

It can be a moving target so remain flexible

Do no harm and you can do a lot of good

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