Welcome to Jeopardy! New Drugs of 2012 Brand/ Generic Indication Mechanism What’s New? Potpourri The Categories Brand/ Generic Indication What’s New? Mechanism Potpourri 200 200 200 200 200 400 400 400 400 400 600 600 600 600 600 800 800 800 800 800 1000 1000 1000 1000 1000 Brand/Generic 200 The generic name for Ximino. Brand/Generic 200 What is minocycline? Ximino is a new extended release formulation of minocycline indicated for the use of moderate to severe acne. Brand/Generic 400 The brand name for avanafil. Brand/Generic 400 What is Stendra? Stendra (avanafil) is the newest member of the PDE-5 Inhibitor class used to treat erectile dysfunction. Brand/Generic 600 The is the brand name for the newest inactivated influenza vaccine. Brand/Generic 600 What is Flucelvax? Flucelvax utilized cultured animal cells to manufacture the vaccine instead of fertilized chicken eggs. Brand/Generic 800 The generic name for bedaquiline. Brand/Generic 800 What is Sirturo? Bedaquiline is a new antimycobacterial used to treat drug-resistant tuberculosis. Brand/Generic 1000 The brand name for teriflunomide. Brand/Generic 1000 What is Aubagio? Aubagio is the second oral medication for the treatment of relapsing Multiple Sclerosis. Indication 200 The new inhaled anticholenergic medication to treat COPD. Indication 200 What is Tudorza Pressair (aclidinium)? Tudorza Pressair is an anticholinergic medication dosed twice daily for the management of COPD. Aclidinium is selective for the M3 receptor. Indication 400 The new omega-3 fatty acid used to treat severe hypertriglyceridemia. Indication 400 What is Vascepa (icosapent ethyl)? Icosapent ethyl is indicated to treat triglyceride levels above 500mg/dL. Indication 600 The new partial onset seizure medication. Indication 600 What is Fycompa (perampanel)? Perampanel is an AMPA-type glutamate receptor antagonist indicated as an adjunctive treatment for patients 12 years and older. Indication 800 The new eye drop to treat elevated intra-ocular pressure due to glaucoma. Indication 800 What is Zioptan (tafluprost)? Zioptan is a preservative free, single use prostaglandin analog eye drop. Indication 1000 The new medication to treat overactive bladder. Indication 1000 What is Myrbetriq (mirabegron)? Myrbetriq is a beta-3 agonist which is a novel mechanism of action. What’s New? 200 The new fentanyl formulation. What’s New? 200 What is Subsys? Subsys is the new sublingual spray formulation of fentanyl indicated for the treatment of cancer pain. What’s New? 400 The effervescent tablet formulation of alendronate. What’s New? 400 What is Binosto? Binosto is dissolved in 120mL of room temperature tap water and the patient needs to wait for 5 minutes after effervescences stops before stirring for 10 seconds and drinking. What’s New? 600 The new Vivelle-Dot. What’s New? 600 What is Minivelle? Minivelle is a transdermal estradiol delivery system that is applied twice a week. What’s New? 800 The extended-release formulation of methylphenidate. What’s New? 800 What is Quillivant XR? Quillivant XR is a fixed dose of methylphenidate to treat ADHD. The packing includes a dosing device that should only be used for Quillivant. What’s New? 1000 The new live attenuate influenza vaccine. What’s New? 1000 What is FluMist Quadrivalent? FluMist Quadrivalent will be the only live attenuate influenza vaccine available for the 2013-2014 flu season. There will be two Influenza B strains. Mechanism 200 An erythropoiesis-stimulating agent used in dialysis induced anemia. Mechanism 200 What is Omontys (peginesatide)? Peginesatide is administered once a month and carries a Black Box Warning for the increased risk for death, cardiovascular reactions, and stroke when the target hemoglobin is above 11 g/dL. Mechanism 400 The new direct Factor Xa inhibitor. Mechanism 400 What is Eliquis (apixaban)? The third approved direct Factor Xa inhibitor indicated for non-valvular atrial fibrilation. Mechanism 600 The new stimulant/osmotic laxative combination. Mechanism 600 What is Prepopik (sodium picosulfate, magnesium oxide, citric acid)? Prepopik is indicated for colonoscopy prep. It comes as a powder for reconstitution at time of dosing. Mechanism 800 The anti-diarrheal used in antiretroviral associated diarrhea. Mechanism 800 What is Fulyzaq (crofelemer)? Fulyzaq works by inhibiting intestinal epithelial chloride channels resulting in the decrease of chloride and water secretion into the GI track. Mechanism 1000 The new weight loss medication helping to increase satiety. Mechanism 1000 What is Belviq (lorcaserin) Lorcaserin is a 5-HT2c receptor agonist which is indicated as an adjunct to diet and exercise in patients with a BMI of >30 kg/m2. Potpourri 200 The new HIV combination medication which is dispensed in its original container. Potpourri 200 What is Stribild (elvitegravir, cobicistat, emtricitabine, tenofovir)? Cobicistat is the new “boosting” medication used to increase serum levels of protease inhibitors. Cobicistat does not treat HIV but inhibits CYP450 metabolism resulting in no risk of HIV resistance. Potpourri 400 The OTC inhaler used to treat mild asthma (non-CFC containing). Potpourri 400 What is Asthmanefrin (racepinephrine)? Asthmanefrin is replacing Primatene Mist. The inhaler device is called the EZ Breathe Atomizer and is different from any other inhaler device currenly on the market. Potpourri 600 The new medication used in premature infants which should be stored in the refrigerator and warmed before use. Potpourri 600 What is Surfaxin (lucinactant)? Lucinactant is a lung surfactant indicated to prevent respiratory distress syndrome in premature infants. Potpourri 800 The new antihistamine/steroid combination nasal spray used to treat seasonal allergic rhinitis. Potpourri 800 What is Dymista (azelastine/fluticasone)? Dymista is a prescription only combination used to treat allergic rhinitis with an onset of about 30 minutes Potpourri 1000 The new medication for IBS which should not be used in the pediatric population and actually has a Black Box Warning for children 6 years and younger. Potpourri 1000 What is Linzess (linaclotide)? Linaclotide is a Guanylate Cyclase-C agonist indicated for the use in IBS with constipation or chronic idiopathic constipation. The Black Box Warning is due to the death of juvenile mice when the adult dose was administered.