DEMENTIA Ashley Frazier M.S. CCC-SLP The University of North Carolina Greensboro Learner Objectives Define dementia and its hallmark characteristics Describe ways in which dementias are categorized Identify characteristics of language of dementia Use basic scales and bedside exams commonly used in dementia care Describe SLP role in treatment of patients with dementia Contrast compensatory therapy with rehabilitation Which most accurately defines and describes dementia? O Progressive disease associated with old age that is characterized by impairment of speech, language, and swallowing O Disease with various symptoms associated with Central Nervous System deterioration whose major impairments are in the areas of Cognition, Memory and Communication O Degenerative disease associated with lesions to the brain which most often results in language, memory, and motor disturbance O Devastating and heartbreaking What is dementia? Mixed bag of signs and symptoms of CNS degeneration, complicated by variability, progressive and persistent deterioration of intellectual function Memory • Forgetfulness • Profound Impairment Cognition • Problem Solving/Judgement • Orientation • ADL Communication • Semantics most affected • More automatic structures spared Various types of Dementia are often categorized into which of these? O Cortical/Subcortical Types O Reversible/Irreversible Types O Both of these Categorizing Dementia Reversible vs. Irreversible Cortical vs. Subcortical Cortical vs Subcortical Dementia Examples of Each DAT http://www.youtube.com/watch?v=7wbYEK7O14E&feature=related Huntington’s http://www.youtube.com/watch?v=JzAPh2v-SCQ What differences do you notice between them? Which Category? O Cortical O Subcortical O Reversible Alzheimer’s Disease Alzheimer’s Characteristics Cortical Dementia Disorientation Communication affected Short term memory impaired Long term memory impaired Impaired judgement and abstraction Personality Changes Mini Mental State Exam CLINICAL STAGING OF DAT: NYU/Silberstein Scale p427-428 in textbook Stage 1 (No Cognitive Impairment) Normal mental and motor function. Stage 2 (Very mild decline) Stage 3 (mild cognitive decline) Early Stage Alzheimer’s can be diagnosed in some but not all individuals with these symptoms Stage 4 (moderate cognitive decline) Mild or early-stage DAT Stage 5 (Moderately severe cognitive decline) Moderate or mid-stage DAT Stage 6 (severe cognitive decline) Mid Stage DAT Stage 7 (Very severe cognitive decline) Late Stage DAT “HIV is now becoming one of the leading causes of dementia worldwide…” Sacktor, N. (2002). The Epidemiology of Human Immunodeficiency Virus-Associated Neurological Disease in the Era of Highly Active Antiretroviral Therapy. Journal of Neurovirology, 8(2), 115-121. doi:10.1080/13550280290101094 “Confusion, forgetfulness, cognitive symptoms” HIVD: Acute vs. Chronic Early on, dementia was acute and severe Entire course was often matter of weeks “Mental Disorders can develop into full-blown dementia in just a few days from the appearance of the first symptom, or take as long as two months.” (Lezak, 2004, p275) Since mid-90’s, more often chronic cognitive involvement that spans life of disease May last for years HIV-D Characteristics Subcortical dementia * Psychomotor slowing Memory deficits Impaired executive function Impaired visuospatial function Impaired recall/retrieval *With cortical features – memory is one of the primary deficits Cognitive Profile Executive Function Effect on social skills, communication Work/Activities Memory Effect on HAART adherence Recall & retrieval impact on function Co-morbidity factors HIV Dementia Scale Power, et al. (1995) HIV Dementia Scale: a rapid screening test. J Acquir Immune Defic Syndr Hum Retrovirol. 1995;8(3):273–278 CLINICAL STAGING OF ADC: Memorial Sloan Kettering Scale Stage 0 (normal) Normal mental and motor function. Stage 2 (moderate) Cannot work or maintain the more demanding aspects of daily life, but able to perform basic activities of self-care. Ambulatory, but may require a single prop. Stage 0.5 (equivocal/subclinical) Either minimal or equivocal symptoms of cognitive or motor dysfunction characteristic of ADC, or mild signs (snout response, slowed extremity movements), but without impairment Stage 3 (severe) of work or capacity to perform activities of daily living Major intellectual incapacity (cannot follow news or (ADL). Gait and strength are normal. personal events, cannot sustain complex conversation, considerable slowing of all output) or motor disability Stage 1 (mild) (cannot walk unassisted, requiring walker or personal Unequivocal evidence (symptoms, signs, support, usually with slowing and clumsiness of arms as neuropsychological test performance) of well). Functional intellectual or motor impairment characteristic ADC, but able to perform all Stage 4 (end stage) but the more demanding aspects of work or Nearly vegetative. Intellectual and social ADL. Can walk without assistance. comprehension and output are at a rudimentary level. Nearly or absolutely mute. Paraparetic or paraplegic with double (urinary and bowel) incontinence. Assessment Full Neuropsych Evaluation likely SLP may be “front line” in early stages Differential dx from similar looking diseases ABCD (AZ Battery Comm Dementia) Global Deterioration Scale “Bedside Eval” – quick tests “Clock Drawing” & Visuospatial Tests Practice: MMSE 3 objects: Apple Table Penny Close Your Eyes Practice: MMSE Scoring Normal score: 24 or higher There are published norms based on age, education, gender. There are norms for native Spanish speakers, and the “very old” population Example: Eighth Grade Education Ages 18 to 69: Median MMSE Score 26-27 Ages 70 to 79: Median MMSE Score 25 Age over 79: Median MMSE Score 23-25 High School Education Ages 18 to 69: Median MMSE Score 28-29 Ages 70 to 79: Median MMSE Score 27 Age over 79: Median MMSE Score 25-26 College Education Ages 18 to 69: Median MMSE Score 29 Ages 70 to 79: Median MMSE Score 28 Age over 79: Median MMSE Score 27 Comfort with MMSE? O Very Comfortable O Sort of Comfortable O Not very comfortable O Can’t figure it out Impact of Dementia "For me, disabled is not being able to keep up, not being able to fully function, and feeling the guilt, and feeling the sadness and the emptiness, the loss. That's disability – just feeling exhausted and worn out" (study participant, O'Brien, Bayoumi, Strike, Young, & Davis, 2008) Impact of Dementia Disruption in self-care abilities Slowed information processing Impaired problem solving Changes in affect Reduced social functioning Failure to adhere to medication regimen Very difficult for caregivers Which describes the role of the SLP in the treatment of clients with dementia? O Build memory skills so that patient can function more effectively at work and home O Help patient become more focused and clear in conversations with friends and family members to reduce frustration O Develop compensatory strategies for deteriorating skills to support participation in daily activities and connection to loved ones Role of SLP Develop strategies to compensate for cognitive changes Critical to maintain medical compliance Support for family/caregiver Increased responsibilities as disease progresses Society not very supportive Enabling meaningful connection with patient vital Role of SLP (ASHA) Increase reliance on spared systems and decrease dependence on impaired ones Strengthening of knowledge and processes that have the potential to improve Design interventions that will evoke a positive emotion in the client http://www.asha.org/docs/html/TR2005-00157.html Role of SLP (ASHA) Must consider the cultural background of their clients Direct intervention: work directly with individuals who have dementia Indirect intervention: environmental modifications, development of therapeutic routines and activities, and caregiver training http://www.asha.org/docs/html/TR2005-00157.html Role of SLP - Strategies Restorative Promote recovery and restore function Compensatory Internal Enhanced Learning Mnemonics External Environmental Modifications External Aids Parsons & Robertson http://www.medscape.com/viewarticle/513278 Singing For The Brain http://www.youtube.com/watch?v=J4S_FX9bieg&feature=BF&playnext=1&list=QL&index=3 The “Other” Role of SLP ASHA has a progressive nondiscrimination statement which includes “sexual orientation” as a protected status and strongly urges the membership to develop cultural competence as a matter of ethical service delivery. Counseling Education Advocacy http://www.asha.org/docs/html/PS2005-00118.html