John Campbell 1 Reasons for use How Steroids work The Law Common Steroids PCT Reducing harm How they are taken Harms Risks 2 Poor UK survey Data Small area or location studies Glasgow accurate NEO data Steroid Comparison - 4 Years 04/05 05/06 06/07 07/08 65% 60% 55% 50% Percentage 45% 40% 35% 30% 25% 20% 15% 10% 5% 0% New Steroid User Steroid Needles Issued Details Total Steroid User Visits Steroid use 'on par with heroin' 2007 Steroid use may be more than twice as common as official figures suggest, a leading expert has told the BBC. According to the British Crime Survey there are 42,000 regular anabolic steroid users in the UK. Drugs expert Jim McVeigh said there could be as many as 100,000. "Basically we're looking at numbers being on a par with heroin users," he added. One treatment centre in Merseyside reports that steroid use has rocketed in the last three years. Staff now treat four new steroid users for every new heroin user - a reversal of the situation in 2004. There is a particular problem with users aged under 25. Drugs Injected at Registration 3000 2599 2500 2000 Amphetamines 1500 1000 500 0 Cocaine 982 20 180 34 Crack 160 Heroin Pieds Melanotan 6 New Registrations GDCC 2012 – 2013 (drugs injected) 461 PIEDs (e.g. steroids, growth hormone) 179 Heroin 52 Tanning Agent (e.g. melanotan) 9 Cocaine 3 Amphetaime 0 100 200 300 400 500 7 Established in 2009 Drop in service – 1 evening per week Staffed by 2 workers and nurse ( supported by lead medical officer) Based in the GDCC and supported by Turning Point 8 To provide a specialised and accessible service. To raise the awareness of the risk of BBV (Blood borne virus) and related infections. To identify ‘other’ harms and complications Provide alternatives to PIEDs use To improve injecting techniques To direct individuals to their local pharmacy needle exchanges for future transactions. 9 SUCCESSFUL Referrals from other exchanges Gym buddies Dealers Forums UNSUCCESSFUL Gym owners Supplement Stores Poster displays 11 Needles and paraphernalia provision, including water for injection. Safer injecting advice and demonstrations Alternatives such as diet and Consultations/assessments Discussions on; ‘harmful’ Wound identification doses, understanding Product identification Blood tests ‘labels’ and syringe markings exercise 12 Date Collected HIV NEG NEG NEG NEG NEG NEG HEP B NEG NEG NEG NEG NEG NEG HEP C NEG NEG NEG NEG NEG NEG Test Declined No No No No No No Abnormal U&E No No No Yes No No No Abnormal LFT No Yes No No Yes Yes No Abnormal Cholestrol No No Yes No Yes No No Abnormal Hormones Yes Yes Yes Yes Yes Yes Yes Repeat Test No No No No No No No 13 Image enhancing Athletic/sports Non-athletic training Occupational Dysmorphia/ self esteem SIMILARITIES Stigma Method of administration Poly drug use How bought Dependency DIFFERENCES Self perception How bought Legality Self welfare Social status? Ratio of men to women No instant gratification 15 • • They are synthetically produced variants of the naturally occurring male sex hormone testosterone. “Anabolic” refers to musclebuilding, and “androgenic” refers to increased male sexual characteristics. “Steroids” refers to the class of drugs. These drugs can be legally prescribed to treat conditions resulting from steroid hormone deficiency, such as delayed puberty, as well as diseases that result in loss of lean muscle mass, such as cancer and AIDS. Natural Test production HYPOTHALAMUS GnRH PITUITARY LH FSH TESTES Testosterone 18 Anabolic/Androgenic steroids : to increase bulk, strength and power Oestrogen-blockers: to block symptoms of feminisation Diuretics: to remove excess water Fat-burners: to remove excess fat and “cut up” Growth Enhancers: to promote new cell growth Post-cycle treatments: to stimulate natural testosterone production Injectable tanning agents: to stimulate pigmentation Sustanon 250/Omnadren (sust) Testosterone Cypionate (cyp) Testosterone Enanthate (test) Testosterone Propionate (prop) Trenbolone (tren) Nandrolone (Deca Durabolin deca) Stanozolol solution (Winstrol winny) Methenolone (primobolan primo) Boldenone (equipoise) Various blends emerging Testosterone Undecanoate (andriol) Oxymetholone (Anadrol/oxies) Oxandrolone (oxandrin - Anavar) Methandrostenolone (Dianabol d-bol) Stanozolol tablets (Winstrol winny) ORAL STEROIDS CAN BE MORE HARMFUL THAN INJECTABLES Pharmaceutical grade Good quality but often low in strength and amounts Underground May be poor quality/unsterile often high concentrations Veterinarian Not designed for human use Counterfeit Often contain no active product and may be unsafe 24 Miscellaneous Fat Burners Anti-estrogen & PCT Human Growth Hormone Ephedrine Human Chorionic Gonadotrophin GHRP 2 & 6 Clenbuterol Nolvadex (tamoxifen) CJC 1295 T3 Clomid Citrate LR3 T4 Arimidex IGF -1 ECA stack Insulin Letrozole Melanotan 1&2 Viagra hGH (and the IGF-1 that is a result of its use) is the only substance that can actually initiate hyperplasia (new cells). GH is produced by the pituitary, IGF-1 is produced primarily by the liver in response to GH It requires careful storage, handling and preparation Many newer peptides also work in a similar way Melanotan is a hormone that stimulates melanin production Other reported benefits: • weight loss • increased libido • healthy spot free skin Stacking: taking several different steroids at the same time Cycling: taking multiple doses over a period of weeks or months, stopping, then starting again. Pyramiding: slowly increasing amount of steroids taken over 612wks, then decreasing the amount slowly ‘Addictive’ behavioural patterns are easily identifiable Cost £200 Cost £200 Cost £50 Cost £45 29 Cost £320 Cost £80 Cost £160 Cost £100 Cost £1000 Cost30£70 After the cycle comes the crash The body enters a ‘catabolic’ state Testes become de-sensitised FSH and LH are not produced/released Estrogen level rise Lethargy and low mood can set in 31 8 Week Cycle 50 Steroid crash -low Test 45 40 35 T e s t 30 L e v e l 20 natural test 25 Steroid Test Estrogen 15 10 5 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 32 “An unproven and unfounded assumption has been made in the medical establishment that the treatment for an individual suffering from ASIH is to do nothing which is coined ‘watchful waiting’ and in time HPTA functioning will return to normal” Doctors appear to be treating the symptoms of low test, not the cause 33 Idea is to accelerate and restore the body’s endogenous test production There are many different views on how this can be achieved However, most involve the same drugs……….. 34 HYPOTHALAMUS GnRH PITUITARY LH FSH TESTES Testosterone 35 • • One of the most detrimental thing that could happen is the stunting of growth plates Other complications involve extreme bone pain, liver toxicity, vascular damage, kidney damage, and joint problems 38 • Changes in the reproductive system • Birth defects (virilisation of female foetus) • Development of a more masculine physique, shrinkage of the breast tissue, deepening of the voice, male pattern baldness and coarse skin. 40 Shrinking of the testicles temporary Reduced sperm count - infertility Sexual dysfunction Prostate enlargement Baldness Gynaecomastia - development of breasts Acne High Blood Pressure Mood swings Jaundice/liver damage Pain in the joints (esp with Winny or hGH) Urinary problems Increases in LDL (bad cholesterol) and decreases in HDL (good cholesterol) Modification in the left ventricle of the heart, with serious implications Increased risk of developing heart related complications/stroke DSM IV - Drug dependency occurs if: The drug is taken higher doses or for longer than intended Unsuccessful efforts to stop or cut down Excessive time spent obtaining or using the substance Important activities are given up Continued use despite negative health effects Need for higher amounts to be taken for the desired effect Withdrawal symptoms occur 43 If people are “addicted” to using these substances what interventions may help? Do we work with PIEDs users in the same way as we would other drug users? If we need to change our approach how do we do this? 44 Talking therapies Continued use due to fear of muscle loss – CBT Medical interventions Dealing with steroid cravings – Relapse Prevention Unwillingness to stop MI Depression post cycle – antidepressants Loss of sexual function Viagra Hypogonadism – HCG & Clomid 45 Avoid counterfeit and underground Use reasonable dosages and stacks Avoid toxic oral steroids Get regular blood tests Use testosterone as a first choice? Use proper injecting tech Use only the safest drugs Always cycle Always consider risk and reward 46