HAD Unit I Review Tom Eck, ecktw@umdnj.edu CALM Resources http://njms.umdnj.edu/calm I will email you the link again tonight. Today’s review and a number of other resources should be up by tomorrow afternoon. To activate your “clicker” Press Ch – 52 – Ch Unit I Priorities 1) 2) 3) 4) 5) 6) 7) 8) 9) Nervous System Principles Lymphatics Lungs Heart Mediastinum Back Upper Limb Surface Anatomy Embryology Nervous System Principles the second most important content from Chapter 1 most important: anatomical terms, but they are rarely tested directly the structure of peripheral nerves as they exit the spinal cord the anatomical and functional distinctions between the sympathetic and parasympathetic divisions of the autonomic nervous system dermatomes (T4 = nipple; T10 = umbilicus) referred pain To which segments does heart pain refer? 0% – T6 – T3 T1 – T4 0% T1 2 0% T8 0% 5 0% –C 5. C3 4. 5 3. –C 2. C1 – C5 C3 – C5 T1 – T4 T3 – T8 T6 – T12 C1 1. 10 Seconds Remaining Referred Pain A high-yield topic; especially important in Unit III, but don’t neglect this Remember: In referred pain, start by identifying the visceral nerves involved Sympathetics From there, identify the spinal segments represented by the nerve(s) T1 – T4/T5 The pain will refer to the corresponding dermatomes. Which of the following, if cut, would block sensory perception in the corresponding dermatome? ventral root 2. dorsal root 3. ventral ramus 4. dorsal ramus 1. m ra sa l do r ve nt ra lr am ot ro sa l 0% us 0% us 0% do r ve n tra lr oo t 0% 10 Seconds Remaining Rhizotomy S – Sensory A – Afferent M – Motor E – Efferent D – Dorsal A – Afferent V – Ventral E – Efferent The dorsal root of spinal nerves can be cut to relieve intractable pain Alternately, the ventral root may be cut to treat spastic paralysis Lymphatics Don‘t forget to study lymph! You can expect a few lymph questions on every exam (~2-3), often relating to the spread of cancer These tend to be challenging, detail-oriented questions Major Topics ◦ Lymph Drainage of the Lung ◦ Lymph Drainage of the Axilla and Breast Into which vessel does lymph from the right arm empty? Thoracic Duct 2. IVC 3. Right Jugular Vein 4. Right Subclavian Vein 1. 0% n Ve i tS ub cla vi an ar Ri gh tJ ug ul Ri gh Th or ac :10 0% Ve in IV C 0% ic Du c t 0% Lymph from the right arm drains to the right lymphatic duct, and to the right subclavian vein (at the venous angle) from there. Which of the following correctly stages the path of pulmonary lymphatic flow? 1. 2. 3. 4. Pulmonary Tracheobronchial Bronchopulmonary Paratracheal Tracheobronchial Deep Cervical Tracheobronchial Paratracheal Deep Cervical Pulmonary Paratracheal Aortic Arch :10 A patient presents with a severe case of pneumonia. When you ask her to lift her arms, you notice that the veins in her upper limbs remain distended. You suspect radical enlargement of which group of lymph nodes: ra hi a .. . 0% ob ro nc ch e ar y( . .. 0% rT rio In fe tB ro n ch op u lm on pu l m on a on a on ch o Br Le f gh t Ri 0% r. . . ry 0% m tP ul on ar y 0% m 5. Le f 4. 10 Pu l 3. gh t 2. Right Pulmonary Left Pulmonary Right Bronchopulmonary (Hilar) Left Bronchopulmonary (Hilar) Inferior Tracheobronchial (Carinal) Ri 1. SVC Syndrome Veins of head and upper extremities become distended due to constriction of the SVC by a tumor or grossly enlarged lymph nodes The bronchopulmonary nodes at the right lung hilus are in close proximity to the SVC Hilar Nodes SVC The Lungs Differences between Left and Right Lungs Lobes, Segments Pleura, Reflections, Recesses Pneumothorax: in tension pneumothorax, mediastinum contralateral side Aspirated Objects Right Main Bronchus Upon examining a patient with left-sided ptosis, miosis, and anhydrosis, a physician suspects a growing superior lobe tumor. Which of the following segments is most likely involved? 6. 0% 0% 0% 0% 0% 0% rio r co po st er io r An te Su rio pe r r io rL in gu In la fe r rio rL in gu lar 5. Ap i 4. Po st e 3. ca l 2. Apical Posterior Apicoposterior Anterior Superior Lingular Inferior Lingular Ap i 1. 10 Seconds Remaining Horner Syndrome Sympathetic Trunk -Interruption of Sympathetics to Head causes Ipsilateral Ptosis (Lid Lag), Miosis (Pupil Constriction), and Anhydrosis (Lack of Sweating) -often caused by Pancoast Tumor -remember to study lung segments; you can expect a few questions testing their locations, both in the written exam and the practical Which space is entered when a thoracentesis is performed at the MAL in the 9th ICS? 0% ic a rd ial re c Pe r st in al ia ed Co st om 0% sa c ss re ce at ic m ap hr ag 0% es s 0% ot ch cn di a s in us 0% Ca r 5. Co st od i 4. rs e 3. sv e 2. Transverse sinus Cardiac notch Costodiaphragmatic recess Costomediastinal recess Pericardial sac Tr an 1. 10 Seconds Remaining The Heart pathway of blood – valve pathologies coronary vessels – consequences of blockage auscultation sites – pathological heart sounds (continuous machine-like murmer = patent ductus arteriosus) radiographs and CTs especially important Identify the heart chambers marked B and D: B gh t Ri c le 0% ef tV en tri iu m At r iu m ,L tri c le ef tA Ve n gh t Ri gh t Ri 0% ,L ef tA tr tri u t. . . At r iu m ,L c le ,L ef tV en :10 0% m 0% D tri 4. Ve n 3. gh t 2. Right Ventricle, Left Ventricle Right Atrium, Left Atrium Right Ventricle, Left Atrium Right Atrium, Left Ventricle Ri 1. CT Scans Right Ventricle is associated with the anterior (sternocostal) surface of the heart Left Atrium is associated with the posterior surface of the heart, just anterior to the esophagus CT’s and Radiographs show up in the written exam and the practical Be able to identify major structures Which of the following will result a diastolic murmur at the apex of the heart? Note: 2 is also correct tic ve Ao r Va l ry on a m 0% 0% 0% In su ffi ... Va Ao lve rti St cV en al os ve is In su ffi cie nc y St en os is 0% lve Va Pu l M itr :10 al In su ffi ci en cy 0% lve 5. Va 4. al 3. itr 2. Mitral Valve Insufficiency Mitral Valve Stenosis Pulmonary Valve Insufficiency Aortic Valve Stenosis Aortic Valve Insufficiency M 1. Aortic Valve Insufficiency blood rushes back into the left ventricle as the ventricle relaxes murmur is heard at the apex (not at the right upper sternal border) because the blood flow causing the murmur is reversed (APTM 2245 does not always apply) associated with a collapsing pulse causes left ventricular hypertrophy, as the heart attempts to compensate for decreased pumping efficiency Insufficiency = Backflow of Blood a.k.a. incompetence, regurgitation A patient is diagnosed with left atrial hypertrophy. Which of the following valve defects is most likely to have caused this condition? I.. . Va lve Ao r tic Va tic Ao r 0% lve v. .. Va l on a m 0% S. .. 0% ry lve Pu l Va al :10 0% S. .. 0% v. .. 5. itr 4. Va l 3. M 2. Tricuspid Valve Insufficiency Mitral Valve Stenosis Pulmonary Valve Insufficiency Aortic Valve Stenosis Aortic Valve Insufficiency Tr ic u sp id 1. Mitral Valve Stenosis Causes left atrial hypertrophy; the left atrium grows larger to generate the force necessary to push past the obstruction Stenosis is often associated with hypertrophy of the preceding chamber Following an acute myocardial infarction, necrosis develops at the apex of the heart. Which vessel was likely occluded? 3. 4. 5. 0% 0% 0% 0% 0% tC ir c um fle Co x An ro na te ry rio s in rI nt us e Po rv en st er tr io icu rI la nt r er ve nt r ic ul ar Ri gh tc or on ar y 2. Left Circumflex Coronary sinus Anterior Interventricular Posterior Interventricular Right coronary Le f 1. 10 Seconds Remaining The Anterior Interventricular Artery (LAD) supplies the anterior twothirds of the interventricular septum, the apex, and the anterior left and right ventricles. It is the most commonly occluded coronary artery. The Mediastinum be able to trace the course of the major structures that pass through the mediastinum localize structures to each mediastinal compartment At which level does the trachea bifurcate? 7 0% T6 /T 0% 6 0% T5 /T 0% 5 0% T4 /T 5. 4 4. T3 /T 3. 3 2. T2/T3 T3/T4 T4/T5 T5/T6 T6/T7 T2 /T 1. 10 Transverse Thoracic Plane divides the mediastinum into superior and inferior compartments passes through the T4/T5 intervertebral disk posteriorly and sternal angle anteriorly bifurcation of the trachea boundary between cardiopulmonary and abdominopelvic sympathetics (greater, lesser, and least splanchnic nerves) Remember: cardiopulmonary = postsynaptic; abdominopelvic = presynaptic You see a patient with a hoarse voice and a detectable suprasternal pulse. Which of the following diagnoses might explain these symptoms? ng ng i pi Im or ss 0% gA bs ce Lu n .. e. on An tic Ao r Tu m 0% th eu ry Ao rta he of t :10 0% sm 0% n 4. at io 3. rc t 2. Coarctation of the Aorta Aortic Aneurysm Tumor Impinging on the Left Subclavian Artery Lung Abscess Co a 1. Aortic Aneurysms Localized dilation of the aorta If in the vicinity of the aortic arch, it may impinge on the left recurrent laryngeal nerve, causing hoarseness If the aneurysm grows large enough, it may lead to a detectable pulse suprasternally A patient has been diagnosed with an esophageal hernia, a condition in which part of the stomach passes through an enlarged esophageal hiatus. At which spinal segment has the herniation occurred? 10 Seconds Remaining 0% 0% 0% 0% 0% T1 2 5. T1 1 4. T1 0 3. T9 2. T8 T9 T10 T11 T12 T8 1. Structures that pass through the Diaphragm I Ate Ten Eggs AT Noon I8 10 E A2T 12 T8: IVC (“Caval Opening”) T10: Esophagus (Vagus too) (“Esophageal Hiatus”) T12: Aorta, Azygos Vein, Thoracic Duct (“Aortic Hiatus”) In which compartment of the mediastinum is the IVC located? r rio id dl M 0% Po st e 0% e 0% r 0% An te rio 4. r 3. 10 io 2. Superior Anterior Middle Posterior Su pe r 1. Mediastinal Compartments Superior Thymus, Phrenic Nerve, Vagus Nerve, Esophagus, Trachea, Thoracic Duct, Azygos Vein, SVC, Aortic Arch, Brachiocephalic Vein, Left Common Carotid Artery, Left Subclavian Artery Anterior Thymus Middle Heart, Phrenic Nerve, Ascending Aorta, SVC, IVC, Pulmonary Arteries/Veins Posterior Descending Aorta, Esophagus (With Vagus Nerve), Thoracic Duct, Azygos Vein, Splanchnic Nerves Bolded structures are exclusive to that compartment. The Back Morphological distinctions between cervical, thoracic, lumbar, sacral, and coccygeal vertebrae Curvatures Spinal Cord Structure Vascular Supply: vertebral arteries, segmental medullary arteries (especially the artery of Adamkiewicz) Which of the following prevents posterior displacement of the dens? rs e lig am en s en t 0% sv e Tr an ra te b Ve r 0% pr om in al m er La t ra 0% as se s 0% rc h h 0% An te rio 5. rc 4. ra 3. rio 2. Posterior arch Anterior arch Lateral masses Vertebra prominens Transverse ligament Po st e 1. 10 In a case of suspected meningitis where should a lumbar puncture be performed? 0% 0% 0% 0% 0% L5 /S 1 5. L4 /L 5 4. L3 /L 4 3. L2 /L 3 2. L1/L2 L2/L3 L3/L4 L4/L5 L5/S1 L1 /L 2 1. 10 Lumbar Puncture Spinal Cord ends at L1/L2 What landmarks are used to find the location for a spinal tap? Anterior superior iliac spines 2. Posterior superior iliac spines 3. Iliac crests 4. Spinalis parts of erector spinae muscles 1. cc .. . pa rt so fe r io ri up e Sp i na l is rs rio 0% re ct or re st s 0% Ili a cs lia cs lia ri er io Po st e rs up An te rio 0% ... p. .. 0% 10 High points of iliac crest correspond to L4 spinous process 0% 0% 0% 0% L5 4. L4 3. L3 2. L2 1. A patient is suffering from a herniation of the L4/L5 IV disc. Which nerve root is most likely compressed? L2 L3 L4 L5 10 Herniated Discs In a herniated disc of the lumbar vertebrae the nerve that exits at that level is spared, while the nerve root one segment below is often compressed For lumbar roots, that means a herniation of IV disc L2/L3 will compress the L3 root The rule applies the same for cervical vertebrae: C5/C6 C6 root For cervical vertebrae, however, it is the nerve exiting at that level is actually compressed; it is only because there is one “extra” cervical nerve that the rule still applies The Upper Limb questions almost entirely neuromuscular (nerve deficits are BIG) BRACHIAL PLEXUS know the spinal segments represented by major nerves (e.g. long thoracic, suprascapular, dorsal scapular, radial, axillary, median, ulnar, musculocutaneous, phrenic) know major actions of each muscle (groupings and locations help) memorize the innervation of each muscle ◦ Innervation gives clues about action, vice versa attachments A young man notices that following a stab injury he has difficulty doing push-ups, noting that his right shoulder blade tends to “stick out.” Which nerve was most likely injured to cause this deficit? c 0% Ph re ni us r 0% Va g ho r gT 0% ul a ac ic 0% Su bs ca p 0% r 5. Lo n 4. pu la 3. Sc a 2. Dorsal Scapular Long Thoracic Subscapular Vagus Phrenic Do rs al 1. 10 Winged Scapula = Long Thoracic Nerve (C5, C6, C7) “5-6-7, wings to heaven” A patient presents with a medially rotated, adducted arm and extended, adducted forearm. Which spinal segments are represented in the injury? 0% 0% 0% 1 0% C8 ,T 0% C7 ,C 8 5. C5 ,C 6 4. C6 3. C4 ,C 5, 2. C3, C4 C4, C5, C6 C5, C6 C7, C8 C8, T1 C3 ,C 4 1. 10 Erb-Duchenne Palsy C5, C6 = “waiter’s tip” sign Medially rotated arm due to loss of Infraspinatus (Suprascapular Nerve) Adducted arm due to loss of Deltoid (Axillary Nerve)/ Supraspinatus (Suprascapular Nerve) Extended forearm due to loss of forearm flexors (Musculocutaneous) Klumpke palsy = C8, T1 (symptoms similar to ulnar nerve palsy) Which of the following does not branch off from or derive from the medial cord? 0% ar lA nt eb ra ch ia l lP ec to r l M ed ia ec to ra 0% Ul n 0% M ed ia 0% al 0% n 5. al P 4. er 3. La t 2. Median Lateral Pectoral Medial Pectoral Ulnar Medial Antebrachial M ed ia 1. 10 Which of the following muscles rotates the glenoid cavity superiorly? 0% 0% bo i d d m m in or aj or is na l Rh om bo i Sp i ez iu Tr ap 0% Rh om 0% s 0% ae 5. ap ul 4. Sc 3. at or 2. Levator Scapulae Trapezius Spinalis Rhomboid major Rhomboid minor Le v 1. 10 Descending fibers elevate the scapula and rotate the glenoid cavity superiorly CN XI Palsy makes arm abduction more difficult Which of the following does not insert into the intertubercular groove of the humerus? in re sm Te Te re s m ajo r is al to r Pe c 0% or 0% m aj or 0% do rs i 0% us 4. im 3. iss 2. Latissimus dorsi Pectoralis major Teres major Teres minor La t 1. 10 Attachments “lady between two majors” teres major, latissimus dorsi, and pectoralis major insert in the intertubercular groove attachments are likely to appear in 3 or 4 questions learn the “hotspots”: intertubercular groove, greater and lesser tubercles of humerus, supra- and infra-glenoid tubercles, coracoid process, coronoid process, olecranon, medial epicondyle of humerus, lateral epicondyle of the humerus, extensor expansion for most other attachment sites, a more general idea will suffice (i.e. what bone(s)) After fracture of the clavicle, which muscle is responsible for the palpable fragment? Trapezius 2. Sternocleidomastoid 3. Pec Major 4. Pec Minor 1. St e rn oc le M in o r 0% Pe c M ajo r 0% Pe c id o m as to i ez iu Tr ap 0% d s 0% 10 Sternocleidomastoid What nerve may be injured following fracture of the surgical neck of the humerus? ar 0% Ul n n 0% M ed ia 0% l 0% di a 4. Ra 3. lla ry 2. Axillary Radial Median Ulnar Ax i 1. 10 What nerve may be injured following fracture of the medial epicondyle of the humerus? ar 0% Ul n n 0% M ed ia 0% l 0% di a 4. Ra 3. lla ry 2. Axillary Radial Median Ulnar Ax i 1. 10 What nerve may be injured following fracture of the radial groove of the humerus? ar 0% Ul n n 0% M ed ia 0% l 0% di a 4. Ra 3. lla ry 2. Axillary Radial Median Ulnar Ax i 1. 10 Surgical neck – axillary Radial groove – radial Distal end of humerus – median Medial epicondyle - ulnar A man fractures his humerus at the spiral groove. What neurological problem is likely to be observed? 0% Ha nd of Sim be ne ia n di ct ha io n nd 0% ro p 0% W r is td 0% nd 4. ha 3. w 2. Claw hand Simian hand Hand of benediction Wrist drop Cl a 1. 10 This would damage the radial nerve leading to loss of extension at the wrist (wrist drop) the radial nerve innervates extensors of the forearm, wrist, and most extensors of the phalanges Following a laceration to the palm just medial to the thenar eminence, which of the following intrinsic movements of the thumb is likely to be fully intact? 0% n tio Ad du c xio n tio 0% n 0% Fle 0% Ab du c 4. n 3. os iti o 2. Opposition Abduction Flexion Adduction Op p 1. 10 Recurrent Branch of Median Nerve opponens policis, abductor policis brevis, and flexor policis brevis are all innervated by the recurrent branch of the median nerve (which is likely to have been lacerated here) Adductor policis is innervated by the ulnar nerve A complete avulsion of the lateral epicondyle would be least likely to disrupt the functioning of which muscle? 0% 0% 0% ca rp Ex iu te ns ln ar or is po llic is Ex lo te ng ns us or di git im in im i so r Su pi n at or 0% Ex te n ru m 5. 0% git o 4. di 3. so r 2. Extensor digitorum Supinator Extensor carpi ulnaris Extensor pollicis longus Extensor digiti minimi Ex te n 1. 10 Extensor pollicis longus does not have its origination at the lateral epicondyle; all others listed do Which of the following resists inferior displacement of the humeral head in the glenoid cavity? 0% of of t tri c ric e ps ep sb b. .. ... 0% La t er al h ea d d lh ea M ed ia of th e tri ce ps . .. 0% d 3. gh ea 2. Long head of the triceps brachii Medial head of triceps brachii Lateral head of triceps brachii Lo n 1. 10 Long Head of the Triceps stabilizes the head of the abducted humerus in the glenohumeral joint, resisting inferior displacement attaches to the infraglenoid tubercle The nerve that provides sensory innervation to the posterolateral forearm branches from the… 0% eo . .. ta n oc u ar ne r ve 0% M us cu l ve er ln di a Ra ed ia 0% Ul n 0% lC or d 0% M 5. or d 4. rc 3. rio 2. Posterior cord Medial Cord Radial nerve Ulnar nerve Musculocutaneous nerve Po st e 1. 10 The posterior antebrachial cutaneous nerve arises from the radial nerve major nerves of the upper limb often terminate as cutaneous nerves knowing the distribution of these sensory nerves helps to identify the major nerve involved in the deficit Describe the anatomical location of the long head of the triceps. .. or a m te re s An te rio rt o o rt An te rio 0% in aj or . .. te re s o rt te re sm h Po st er io 0% .. . 0% bo th te re sm .. . 0% bo t 4. o 3. rt 2. Anterior to both teres major and teres minor Posterior to both teres major and teres minor Anterior to teres major and posterior to teres minor Anterior to teres minor and posterior to teres major An te rio 1. 10 Quadrangular Space Teres minor Teres major Teres minor wraps around the back to the greater tubercle Teres major passes anteriorly to the intertubercular groove The long head of the triceps passes in between Know the quadrangular space The medial humeral circumflex artery and axillary nerve pass through this window Humerus Long head Which part of the hand would experience paresthesia in carpal tunnel syndrome? le itt of l p Ti id dl m of 0% fin ge r ge ef in gio re en ar lb ed Na i Hy po th 0% r 0% n 0% su rf a ce en ce 0% Do rs al 5. in 4. em 3. ar 2. Thenar eminence Dorsal surface Hypothenar region Nail bed of middle finger Tip of little finger Th en 1. 10 The following patient presents with no loss of consciousness, no visible trauma, and no sensory deficits. What is the likely problem? 0% 0% ct ur e re n ’s c on tr n’ sc an km Vo l Du pu yt n. n ed ia 0% on tra ac t da m ag ur e e 0% M 4. am ag e 3. ar n. d 2. Ulnar n. damage Median n. damage Volkmann’s contracture Dupuytren’s contracture Ul n 1. 10 Dupuytren’s Contracture Not due to nerve damage because no associated sensory loss In Volkmann’s you would expect to see wrist involvement as well and would expect a preceding ischemic event, such as the improper wrapping of a tourniquet In Dupuytren’s, also look for the presence of subcutaneous nodules Embryology don’t neglect; a significant portion of the test questions are generally straightforward, focusing on the precursors of adult structures as well as abnormalities heart embryology is especially important for this exam In which of the following conditions does the body compensate by opening up a collateral pathway for blood flow? 0% en os i.. . of . .. St tic Ao r rc t at io m Co a or a 0% n en ... tu s Pa t en tD uc 0% ... 0% en tF F. .. 0% of 5. Pa t 4. lo gy 3. 10 tra 2. Tetralogy of Fallot Patent Ductus Arteriosus Patent Foramen Ovale Coarctation of the Aorta Aortic Stenosis Te 1. Coarctation of the Aorta Diminished femoral pulses and rib notching due to increased blood flow = classic signs of coarctation Collateral Circulation: Aorta Subclavian Internal Thoracic Anterior Intercostal Posterior Intercostal Note: the Supreme Intercostal Arteries represent an additional pathway Collateral circulations are HUGE; know these The chest radiograph of a cyanotic newborn is shown below. Immediately suspecting a congenital abnormality, you anticipate four pathological conditions. Which of the following would you NOT expect to find: lD rS ul a tri c Ve n ep ta al itr M 0% ef ec t os is 0% St en no sis 0% St e on a ry he m Pu l di rri Ao r r. . . ng of t rH yp e cu la 0% ta 0% Ov e 5. tri 4. Ve n 3. 10 gh t 2. Right Ventricular Hypertrophy Overriding of the Aorta Pulmonary Stenosis Mitral Stenosis Ventricular Septal Defect Ri 1. Boot-Shaped Heart Indicates right ventricular hypertrophy seen in Tetralogy of Fallot. (A similar radiograph is in the lab. Remember to review all of these.) Pulmonary Artery Stenosis Right Ventricular Hypertrophy Overriding of the Aorta VEntricular Septal Defect Which aortic arch gives rise to the stapedial artery? 0% Six th Ar Ar c ch h 0% h Ar c h 0% Fif t 0% Fo ur th ch 0% Ar ch 0% Th ir d 6. Ar 5. nd 4. rc h 3. Se co 2. First Arch Second Arch Third Arch Fourth Arch Fifth Arch Sixth Arch Fir st A 1. 10 Seconds Remaining Aortic Arch Derivatives Remember MSCARD Maxillary Stapedial Common Carotid (External Too) Arch of Aorta (and Right Subclavian) Regresses Ductus Arteriosus (and Pulmonary Arteries) Which of the following vessels has the highest oxygen saturation? 0% er y Ar t ry ng A on a di er ie Ri gh t Co r As ce n Ar t m on a ry ry 0% or ta 0% s Ve in s 0% Pu l 4. on a 3. 10 m 2. Pulmonary Veins Pulmonary Arteries Ascending Aorta Right Coronary Artery Pu l 1. An embryo successfully reaches the blastula stage but fails to implant itself in the endometrium. Which of the following events may have failed to occur? 0% 0% rs 0% ye m La Fe m io n at of M al of ea Ge r nd th e of an ce Fu sio n Fo rm av Z.. . a. . ag e 0% Cl e 4. ar 3. 10 pp e 2. Cleavage Disappearance of the Zona Pellucida Fusion of Male and Female Pronuclei Formation of Germ Layers Di sa 1. The blastocyst must “hatch” by dissolving the zona pellucida before implantation A newborn suffers from excessive accumulation of saliva and mucous in nose and mouth, gagging, cyanosis after swallowing milk, abdominal distension after crying, and reflux of gastric contents into lungs. Which congenital abnormality may be to blame? op ha g ea lF gm ph ra Tr ac he o es lD ia ni ta ist ul .. Gr e th e of Co ng e sp os iti o 0% a 0% at .. 0% n ry Hy po pl as ia 0% on a 4. Tr an 3. 10 m 2. Pulmonary Hypoplasia Transposition of the Great Vessels Congenital Diaphragmatic Hernia Tracheoesophageal Fistula Pu l 1. Tracheoesophageal Fistula In most common form (seen at left), esophagus ends in blind pouch Trouble with feeding a prominent symptom at birth The patient with the herniated disc asks you about the embryological precursor to the substance coming out of the disc (naturally, of course). What should be your response? M La t er al P lat e te ed ia rm M es od er ho r No to c In te 0% m 0% es od er m 0% d 0% er m 4. to d 3. ro ec 2. Neuroectoderm Notochord Intermediate Mesoderm Lateral Plate Mesoderm Ne u 1. 10 Nucleus Pulposus is the only remnant of the notochord in the adult human Remember your germ layers Which of the following is not derived from neural crest cells? es 0% an oc yt ro ns ot or Ne u M Ga ng l er ic En t 0% M el 0% ia 0% gli a 4. Ga n 3. Ro ot 2. Dorsal Root Ganglia Enteric Ganglia Motor Neurons Melanocytes Do rs al 1. 10 Neural Crest Cells “the fourth germ layer” know the derivatives and consequences of failed migration Surface Anatomy Generally come in the form, “A stab wound to the _______ will lacerate which of the following structures:” Be able to associate surface structures with the viscera underneath Don’t forget the posterior thorax A stab wound through the manubrium damages a vessel coursing almost horizontally. Which of the following was most likely lacerated? Left Brachiocephalic Vein 2. Right Brachiocephalic Vein 3. SVC 4. Left Common Carotid 1. 0% ot id Ca r ic Le f tC om m on ph al io ce ac h Br gh t Ri 0% SV C n Ve i lic ph a ce hi o ra c tB Le f :10 0% Ve in 0% MAL 1st ICS Posterior Segment of Superior 2nd ICS Posterior Segment of Superior MCL PS Median PS MCL MAL Anterior Segment of Superior Axillary Vessels Anterior Segment of Superior SVC Aortic Arch, Left Brachioc ephalic V. Anterior Segment of Superior Aortic Knob Anterior Segment of Superior Axillary Vessels AP Segment of Superior 1st ICS Ascending Aorta Anterior Segment of Superior Pulmonary Trunk Anterior Segment of Superior AP Segment of Superior 2nd ICS RV Anterior Segment of Superior Conus Arteriosus Superior Lingular of Superior Superior Lingular of Superior 3rd ICS RV Inferior Lingular of Superior LV *Nipple Superior Lingular of Superior 4th ICS Anteromedial Basal of Inferior 5th ICS Anterior Segment of Superior PS of S 3rd ICS 4th ICS Lateral Segment of Middle LS of Middle Anterior Basal of Inferior 5th ICS Anterior Basal of Inferior 6th ICS Anterior Basal of Inferior LS of Middle LS of Middle MS of Middle Anterior Segment of Superior RA MS of Middle Medial Segment of Middle RA MS of Middle Medial Segment of Middle RA/IVC *Nipple LS of Middle Anterior Segment of Superior SVC RV RV DIAPHRAGM RV *No pleura IL of S LV (apex) AMB of Inferior AMB of I LB of I 6th ICS Which heart chamber is at greatest risk from a thoracic stab wound? Ri gh t Ve n tri At r iu m Ri 0% c le 0% gh t tri c tV en :10 0% le 0% Le f 4. iu m 3. tA tr 2. Left Atrium Left Ventricle Right Atrium Right Ventricle Le f 1. MAL 1st ICS Posterior Segment of Superior 2nd ICS Posterior Segment of Superior MCL PS Median PS MCL MAL Anterior Segment of Superior Axillary Vessels Anterior Segment of Superior SVC Aortic Arch, Left Brachioc ephalic V. Anterior Segment of Superior Aortic Knob Anterior Segment of Superior Axillary Vessels AP Segment of Superior 1st ICS Ascending Aorta Anterior Segment of Superior Pulmonary Trunk Anterior Segment of Superior AP Segment of Superior 2nd ICS RV Anterior Segment of Superior Conus Arteriosus Superior Lingular of Superior Superior Lingular of Superior 3rd ICS RV Inferior Lingular of Superior LV *Nipple Superior Lingular of Superior 4th ICS Anteromedial Basal of Inferior 5th ICS Anterior Segment of Superior PS of S 3rd ICS 4th ICS Lateral Segment of Middle LS of Middle Anterior Basal of Inferior 5th ICS Anterior Basal of Inferior 6th ICS Anterior Basal of Inferior LS of Middle LS of Middle MS of Middle Anterior Segment of Superior RA MS of Middle Medial Segment of Middle RA MS of Middle Medial Segment of Middle RA/IVC *Nipple LS of Middle Anterior Segment of Superior SVC RV RV DIAPHRAGM RV *No pleura IL of S LV (apex) AMB of Inferior AMB of I LB of I 6th ICS Which rib does the horizontal fissure approximate most closely? 0% 0% en th 0% Se v 0% th 0% Six 5. h 4. Fif t 3. 10 Fo ur th 2. Third Fourth Fifth Sixth Seventh Th ir d 1. Study Tips Study the TBL’s! Use them to guide your review. Learn the Blue Boxes, especially the Chapter 1 ones (summary online) Don’t forget lymph and embryo! Review as many bodies as possible Mock Practical Saturday morning: 10 am – 4 pm There will be bodies tagged in the lab, as well as radiographs Complete on your own, giving yourself a minute for the A and B questions Tags will be left on until Saturday afternoon Answers will be posted in the lab Good Luck! ecktw@umdnj.edu