Key findings from the 2012 national HIV household survey (SABSSM4) Olive Shisana & Thomas Rehle Human Sciences Research Council (HSRC) Human and Social Dynamics (HSD) Research Seminar Cape Town, 2 December 2014 Background • This is the fourth national population-based survey, three similar surveys were conducted by the same team in 2002, 2005 and 2008. • The study has provided an important gauge of the HIV epidemic of South Africa. • The results are used to both inform and evaluate important health programmes such as the National Strategic Plan (NSP) on HIV/AIDS, STI and TB, and the National Health Insurance, among others. National HIV Household Surveys South Africa • Main survey objectives: - to obtain national, representative data for the entire population - to estimate HIV prevalence & HIV incidence - to measure behavioral / socio-demographic and health indicators • Reporting domains: Age Sex Race Locality type (urban formal, urban informal, rural formal, rural informal) Province National HIV Household Survey South Africa 2012 • Survey period: January 2012 – November 2012 38,431 interviewed 28,997 tested for HIV Laboratory Testing Dried Blood Spot HIV Ab screening PCR (infants) Ab Pos HIV Incidence Testing (> 2 years) Antiretrovirals ARVs HIV PREVALENCE National HIV Household Survey South Africa 2012 • HIV prevalence, total population: 12.2% (2008: 10.6%) • 6.4 million living with HIV/AIDS HIV prevalence by age and sex, South Africa, 2012 HIV prevalence by sex (15-49 years), South Africa, 2012 HIV prevalence by race group (15 – 49 years), South Africa 2012 HIV prevalence by locality type (15 – 49 years), South Africa 2012 HIV prevalence by province (15-49 years), South Africa, 2012 Trends in HIV prevalence in children, South Africa 2002-2012 Trends in HIV prevalence by age, South Africa 2002-2012 HIV prevalence among females, South Africa 2008 and 2012 40 36.0 32.7 35 31.6 28.0 30 28.4 25 21.1 29.1 24.8 19.7 20 17.4 15 14.8 16.3 14.1 10 5 6.7 2.4 9.7 10.2 5.6 7.7 2.4 1.8 0 0 to 14 15 to 19 20 to 24 25 to 29 30 to 34 35 to 39 40 to 44 45 to 49 50 to 54 55 to 59 60+ ANTIRETROVIRAL TREATMENT (ART) EXPOSURE → need to test for ARVs in HIV surveys! ART rollout in South Africa (L. Johnson, SAJHIVMED 2012) 2,000,000 1,800,000 1,600,000 1,400,000 1,200,000 1,000,000 800,000 600,000 400,000 200,000 0 2004 2005 2006 2007 2008 2009 2010 2011 ART Exposure, South Africa mid-2012 Variable National Males Females Estimated number of people living with HIV (n) Estimated Proportion of people number on living with HIV on ART (n) ART (%)[95%CI] 6,422,000 2,002,000 31.2 [28.1-34.5] 2,531,000 651,000 25.7 [21.2-30.8] 3,873,000 1,344,000 34.7 [31.4-38.2] ART Exposure by Age Group, South Africa mid-2012 Variable Estimated number of people living with HIV (n) Estimated Proportion of number of people living with people on ART HIV on ART (%) (n) [95% CI] Age group 0-14 368,879 166,025 45.1 [33.9-56.9] 15-24 720,269 102,868 14.3 [10.0-20.0] 25-49 4,705,506 1,466,412 31.2 [27.4-35.2] 610,323 260,490 42.7 [35.7-50.0] 15-49 5,425,776 1,569,280 28.9 [25.6-32.5] Total 6,422,179 2,002,350 31.2 [28.1-34.5] 50 and older HIV INCIDENCE ESTIMATION Estimating HIV Incidence South Africa 2012 1. Direct HIV incidence using blood specimens - Multi - assay testing algorithm 2. Indirect HIV incidence using mathematical models - HIV incidence estimation from HIV prevalence data collected in repeated national population-based surveys - EPP/Spectrum; Thembisa Social science that makes a difference Direct, assay-based HIV incidence rates by age and sex, South Africa 2012 Age Groups Age ≥ 2years Total Male Female Age 15-24 years Total Male Female Age 15-49 years Total Male Female Social science that makes a difference HIV incidence % (95% CI) 1.07 (0.87 – 1.27) 0.71 (0.57 - 0.85) 1.46 (1.18 - 1.84) 1.49 (1.21 – 1.88) 0.55 (0.45 - 0.65) 2.54 (2.04 - 3.04) 1.72 (1.38 – 2.06) 1.21 (0.97 - 1.45) 2.28 (1.84 - 2.74) Comparison with mathematical models Method Period 15-49 incidence % LAg avidity/ ARV / VL 2012 1.72 Synthetic cohort 2008-12 1.9 EPP/Spectrum 2011/12 1.52 Thembisa 2011/12 1.47 HIV incidence rates by sociodemographic and behavioral variables South Africa 2012 Variables HIV incidence % (95% CI) Locality type (15 years and older) Urban formal Urban informal 1.29 (1.03-1.55) 4.42 (3.42-5.09) Selected at-risk populations Sexually active females 15-24 yrs Black African females 20-34 yrs 3.53 (2.83 - 4.23) 4.54 (3.64 - 5.44) Number of sexual partners in the past 12 months (15-49 yrs) One partner 1.67 (1.33 - 2.01) More than one partner Social science that makes a difference 2.43 (1.95 - 2.91) Behavioural Findings Social science that makes a difference Awareness of HIV status (%) Awareness of HIV status among those who tested in the last 12 months, by sex (15 years and older), South Africa 2005-2012 60 46.3 50 36.4 40 28.7 30 24.7 19.8 20 10 41.5 13.3 10.2 11.9 0 Males Females 2005 2008 2012 Total Condom use at last sex by age and sex, South Africa 2002-2012 Multiple sexual partnerships (15-49 years), South Africa 2002-2012 Age-disparate sexual relationships in the 15-19 years age group South Africa 2005-2012 Sex before the age of 15 years (%) Sexual debut before age 15 years (15-24 years), South Africa 2002-2012 25 20 15 16.7 13.1 11.9 11.3 5.1 5.9 10 5 5.3 5.0 0 2002 2005 Males Females 2008 Total 2012 Correct knowledge of HIV transmission and rejection of major misconceptions (%) Correct HIV knowledge among key populations, South Africa 2008 and 2012 45 40 35 30 25 30.1 26.9 27.6 36.1 2012 National Average (26.8%) 33.6 31.8 27.2 23.3 22.7 25.3 24.7 17.7 20 15 2008 10 2012 5 0 Black African People living Black African Disabled (15 High-risk Recreational females 20- together, not males 25-49 years and drinkers (15 drug users 34 years married (15years older) years and (15 years and 49 years) older) older) Key populations at higher risk of exposure Trends of HIV-related stigma in South Africa, 2005, 2008, 2012 Percentages of respondents aged 15yrs and older who agreed with 4 statements about PLHIV asked in the past 3 surveys 2005 90.7% 92.1% 2008 2012 91.6% 79% 71.1% 72.5% 50.1% 39.9% 30.5% 14.9% If you knew that a shopkeeper or food seller had HIV, would you buy food from them? Would you be willing to care for a family member with AIDS? 15.8% 16.6% Is it a waste of money to train or give a promotion to someone with HIV/AIDS? Would you want to keep the HIV positive status of a family member a secret? ARV prophylaxis Male circumcision Auvert B, PloS Med 2005 Gray R, Lancet 2007 Bailey R, Lancet 2007 Treatment of STIs Grosskurth H, Lancet 2000 Microbicides for women Female Condoms Abdool Karim Q, Science 2010 Oral pre-exposure prophylaxis HIV PREVENTION HIV Counselling and Testing Grant R, NEJM 2010 (MSM) Baeten J , NEJM 2012 (Couples) Paxton L, NEJM 2012 (Heterosexuals) Choopanya K, Lancet 2013 (IDU) Post Exposure prophylaxis (PEP) Scheckter M, 2002 Male Condoms Coates T, Lancet 2000 Sweat M, Lancet 2011 Treatment for prevention Cohen M, NEJM, 2011 Donnell D, Lancet 2010 Tanser, Science 2013 Behavioural Intervention - Abstinence - Be Faithful Note: PMTCT, Screening transfusions, Harm reduction, Universal precautions, etc. have not been included – this is on sexual transmission Research Collaborators Funders This research has been supported mainly by the President’s Emergency Plan for AIDS Relief (PEPFAR) through CDC under the terms of Cooperative Agreement Numbers 5U2GPS000570-05 , 3U2GGH0035702 and U2GPS001328. 1918 – 2013 THANK YOU