Neonatal Drug Calculations Practice Questions

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D. Ann Currie ,RN,MSN
Question # 1
 How many milliliters per kilogram per day is the
neonate receiving, if the neonate is receiving D10W at
7.25 ml/hr for 24 hours and Fat Emulsion 20% solution
at 4.5 ml/hr for 20 hours. Neonate weighs 4.7 lbs.



ml/kg/day
ml/kg/day
 1.
7.25 𝑚𝑙
ℎ𝑟
x
24 ℎ𝑟
𝑑𝑎𝑦

81.446808
 2.
4.5𝑚𝑙
ℎ𝑟

42.127659
 3.


x
20ℎ𝑟
𝑑𝑎𝑦
x
81.446808
+42.127659
123.57446
x
2.2𝑙𝑏𝑠
1
x
1𝑘𝑔 4.7𝑙𝑏𝑠
2.2𝑙𝑏𝑠
𝑘𝑔
x
1
4.7𝑙𝑏𝑠
382.8
=
4.7
=
198
=
4.7
=
ans. 123.57 ml/kg/day
Question # 2
 The infant, who weighs 2,375 grams, is getting 150 mg/
kg/ day of Ampicillin in 4 equal doses, How many
milligrams per dose should be given?






mg/dose
mg/dose
wt. 2375 grams
 2375 grams= 2.375 Kg.



150𝑚𝑔
𝑘𝑔/𝑑𝑎𝑦
x
2.375𝑘𝑔
1
x
𝑑𝑎𝑦
4𝑑𝑜𝑠𝑒𝑠
356.25
=
=
4
89.0625
ans. 89.06 mg/dose
Question # 3
 The infant, who weighs 2,855 grams, will receive how
many micrograms per kilogram per minute when the
Dopamine is infusing at 750 mcg/kg/hr


mcg/kg/min
mcg/kg/min
wt. 2855gm
 2855 grams =2.855 kg.


750𝑚𝑐𝑔
𝑘𝑔/ℎ𝑟
x
1ℎ𝑟
60𝑚𝑖𝑛
=
750
60
= 12.5
ans. 12.5 mcg/kg/min
Question # 4
 The neonate, who weighs 3 lbs 10 oz, will receive how
many milligrams per minute of Dopamine when the
infant is getting 950 mg/kg/hr.


mg/min
mg/min
 Wt = 3 lbs. 10 oz.= 3. 625 lbs



950𝑚𝑐𝑔
𝑘𝑔/ℎ𝑟
x
𝑘𝑔
2.2𝑙𝑏𝑠
x
3.625𝑙𝑏𝑠
𝑘𝑔
x
10/16= .625 & 3 = 3.625
ℎ𝑟
60𝑚𝑖𝑛
=
3443.75
132
26.089015
ans. 26.09 mg/min
Question # 5
 The baby, who weighs 1,667 grams, has an IV of
Dopamine 35 milligrams in 100 milliliters and is
getting 12.5 mcg/kg/minute. What will the nurse set
the IV infusion rate at to delivery 12.5 mcg/kg/min?

ml/hr
ml/hr
wt. 1667 gm.
 Wt 1667 grams =1.667 kg

100𝑚𝑙
35𝑚𝑔
X
1𝑚𝑔
1000𝑚𝑐𝑔
X
12.5𝑚𝑐𝑔
𝑘𝑔/𝑚𝑖𝑛
X
1.667𝑘𝑔
1
X
= 3.5721428

ans. 3.57 ml/hr
60𝑚𝑖𝑛
ℎ𝑟
125025
=
35000
Question # 6
 The neonate weighs 1,922 grams. The physician has ordered
Gentamycin 2 mg per kilogram per dose stat and then every 18 hours
for 7 days.

 A. What is the total number of doses the neonate will receive in 7 days?


total number of doses in 7 days




 B. How many total milligrams will the neonate receive in 7 days?

mg in 7 days.
A. total number of doses in 7 days
Doses /TT
 wt. 1922 grams = 1.922 kg

 Stat =1 dose & doses in÷7days

 7 days = 7 X 24 hrs = 168 hrs.÷ 18hrs per dose = 9.333
doses
 1 & 9 = 10 doses

10 total doses in 7days
B. mg in 7 days=TT.
 Wt. 1.922 kg


2𝑚𝑔
𝑘𝑔/𝑑𝑜𝑠𝑒
X
1.922𝑘𝑔
1
10 doses in 7 days =TT
X
10 𝑑𝑜𝑠𝑒𝑠
=
𝑇𝑇
38.44
ans. 38.44 mg in 7 days
Question # 7
 The physician has ordered Dexamethasone 0.65
mg/kg/day with a dose to be given every 6 hours. The
infant weighs 3 lbs. 8 oz.

 A. How many milligrams per dose will the infant receive?




mg/dose
B. How many milligrams will the infant receive in 24
hours?

mg/24 hrs
A. mg/dose
 Wt. 3 lbs. 8 oz.
= 3.5 lbs
 every 6hrs = 4 doses/day



0.65𝑚𝑔
𝑘𝑔/𝑑𝑎𝑦
X
𝑘𝑔
2.2𝑙𝑏𝑠
X
3.5𝑙𝑏𝑠
1
X
( 8/16= .5 & 3=3.5)
𝑑𝑎𝑦
4𝑑𝑜𝑠𝑒𝑠
=
2.275
=
8.8
0.2585227= 0.26
ans. 0.26 mg/dose
B. mg/24 hrs
 Mg/TT or mg/day
 Wt.= 3.5 lbs.



0.65𝑚𝑔
𝑘𝑔/𝑑𝑎𝑦
X
𝑘𝑔
2.2𝑙𝑏𝑠
X
3.5𝑙𝑏𝑠
1
=
2.275
2.2
=
1.0340909 = 1.03
ans. 1.03mg/day or 24 hrs
Question # 8
 The baby, who weighs 3222 grams, received D10W @ 9
ml/hr for 18 hrs and then it was decreased to 7ml/hr
for 6 hours. Also the baby received a fat emulsion 20%
solution at 2.75 ml/hr for 21 hours. The baby took 28
ml per each feeding for 4 feedings of formula 24 cal/oz
and then 32 ml per each feeding for 4 feedings. How
many calories did the baby receive in 24 hours?



calories/24 hours
Calories/24 hours
 Wt. 3222 grams =3.222 kg
1 oz.=30 ml.
 Calories :
 a. 1 gram glucose=4 calories or 3.4 calories
 b. intralipids 10%= 1.1calories/ 1 ml

20%= 2.2calories/ 1ml
 c. formula= 24 calories/ oz
IV calories
 1) cal/day =
 a.
4𝑐𝑎𝑙
1𝑔𝑚

 b.

X
10𝑔𝑚
100𝑚𝑙
X
9𝑚𝑙
ℎ𝑟
X
18ℎ𝑟𝑠 6480
=
𝑑𝑎𝑦
100
64.8
4𝑐𝑎𝑙
1𝑔𝑚
X
10𝑔𝑚
100𝑚𝑙
16.8

64.8
 & 16.8

81.6
7𝑚𝑙
X
ℎ𝑟
6ℎ𝑟𝑠
X
𝑑𝑎𝑦
1680
=
=
100
=
Intralipids calories
 2) cal/day


2.2𝑐𝑎𝑙
1𝑚𝑙
X
2.75𝑚𝑙 21ℎ𝑟𝑠
X
=
ℎ𝑟
𝑑𝑎𝑦
127.05
Formula Calories
 Cal/day
 3) a.
24𝑐𝑎𝑙
𝑜𝑧
𝑜𝑧
X
30𝑚𝑙
28𝑚𝑙
X
1𝑓𝑒𝑒𝑑𝑖𝑛𝑔
𝑜𝑧
30𝑚𝑙
32𝑚𝑙
1 𝑓𝑒𝑒𝑑𝑖𝑛𝑔
X
4 𝑓𝑒𝑒𝑑𝑖𝑛𝑔𝑠
𝑑𝑎𝑦
=
2688
30
= 89.6

 b.
24𝑐𝑎𝑙
𝑜𝑧
X
89.6
 & 102.4

192
X
X
4 𝑓𝑒𝑒𝑑𝑖𝑛𝑔𝑠
𝑑𝑎𝑦
=
3072
=
30
102.4
Calories per day

81.6
 127.05
 & 192
 400.65
ans. 400.65 calories per day or
 3.4 cal/1 gm glucose
 69.36
 127.05
& 191.9
388.31
ans. 388.31 calories per day
Question # 9
 The infant, who weighs 5 lbs 4 oz, is receiving D12.5W at
4.5 ml/hr for 24 hours intralipids 20% solution at 3.5
ml/hr for 20 hours, and Similac 20 cal/oz every 3 hours
with each feeding being 22 milliliters. Also microlipids
1 ml per 1 oz of formula will be added to formula. How
may calories per kilogram per day is the infant
receiving?


cal/kg/day
Calories /kg/day
 Wt. 5lbs 4oz = 5. 25 lbs ( 4/16=.25 & 5=5.25)
 Calories:

IV 1gram of glucose = 4 calories or 3.4 calories
 intralipids 20%= 2.2calories/ 1 ml
 formula= 20calories/1 oz
 microlipids= 4.5calories/ 1ml
IV Calories
 Cal/kg/day


4𝑐𝑎𝑙
1𝑔𝑚
X
12.5𝑔𝑚
100𝑚𝑙
X
22.628571
4.5𝑚𝑙
ℎ𝑟
24ℎ𝑟𝑠
X
𝑑𝑎𝑦
2.2𝑙𝑏𝑠
1
11880
X
X
=
=
𝑘𝑔
5.25𝑙𝑏𝑠 525
Intralipids Calories
 Cal/kg/day


2.2𝑐𝑎𝑙
1𝑚𝑙
X
3.5𝑚𝑙
ℎ𝑟
64.533333
X
20ℎ𝑟𝑠
𝑑𝑎𝑦
X
2.2𝑙𝑏𝑠
𝑘𝑔
1
3388
X
X
=
5.25 𝑙𝑏𝑠 5.25
Formula Calories
 Cal/kg/day


20𝑐𝑎𝑙
𝑜𝑧
X
1 0𝑧
30𝑚𝑙
22𝑚𝑙
X
3ℎ𝑟𝑠
49.168253
X
24ℎ𝑟𝑠
𝑑𝑎𝑦
2.2𝑙𝑏𝑠
1
2323.2
X
X
=
=
𝑘𝑔
5.25 𝑙𝑏𝑠 472.5
Microlipids Calories
 Cal/kg/day

4.5𝑐𝑎𝑙
1𝑚𝑙
1 𝑜𝑧
X
X
1 𝑚𝑙
1 0𝑧
30 𝑚𝑙
5227.2
=11.062857
472.5
X
22𝑚𝑙
3ℎ𝑟𝑠
24ℎ𝑟𝑠 2.2 𝑙𝑏𝑠
X
X
𝑑𝑎𝑦
𝑘𝑔
1
X
5.25 𝑙𝑏𝑠
=
Calories/kg/day





22.628571
64.533333
49.168253
&11.062857
147.39301
4cal
ans. 147.39 cal/kg/day





18.772662
64.533333
49.168253
11.062857
143.53709
3.4 cal
ans. 143.54 cal/kg/day
The End
 Questions come see me
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