Fibroepithelioma of Pinkus
(Basal cell carcinoma, fibroepithelioma of Pinkus type)
Deba P Sarma, MD
Omaha
M 79, back
Comment
First described by Hermann Pinkus in 1953.
It is a rare variation of basal cell carcinoma with very indolent
clinical course.
Unlike other histologic types of basal cell carcinoma, the tumor
occurs commonly on the sun-protected skin of trunk, especially
back.
Presents as a slowly enlarging, fleshy, raised or pedunculated
papilloma or achrochordon with a broad base on the trunk or the
extremities.
Age: Older adults, M=F
Histology: Fibroepithelioma of Pinkus shows long, thin, branching
and anastomosing strands of basal cell carcinoma within in a
fibrovascular stroma. Many strands show a connection with the
epidermis. The basaloid strands show two types of cells: a lighter
staining cell comprising the bulk of the strand and peripheral, small
darker cells showing palisading pattern.
Unusual examples of fibroepithelioma of Pinkus
Pan Z, Huynh N, Sarma DP. (2008). Fibroepithelioma of
Pinkus in a 9-year-old boy: a case report. Cases Journal 1:21.
PMID: 18588684 [PubMed – indexed for MEDLINE]
Repertinger SK, Stevens T, Markin N, Klepacz H, Sarma
DP.(2008). Fibroepithelioma of Pinkus with pleomorphic
epithelial giant cells. Dermatology Online J 14(12):13.
[Pubmed- indexed for MEDLINE].