What does it all mean? Mike Ackerley Overview What are they? What do they look like? What are the differentials for each? What can I do to diagnose it further? What are they? Interstitial Alveolar Bronchial Mixed What do they look like? Interstitial a.k.a “busy” lungs: smudging or blurring of the outline of structures. Stuff scattered in the outside garbage bag. Structured Nodules - < 3 cm (if you can see them they’re at least 4 – 5 mm) Masses - > 3 cm Differentiate nodules from end on vessels. Less numerous End on vessels more opaque, and smaller in diameter Adjacent to bronchus & have connected “tail” b/c part of vessel projects laterally Unstructured Fluid (non-cardiogenic edema) Cells (pneumonia – bacterial, fungal, viral) Scar tissue (contusions) Age Artifact? What are the differentials? Structured (Nodules/Masses) Mineralization: osteomas (large breed dog, not significant) Solitary (can be cavitary or solid): Perihilar region or caudal lung lobes Tumor Adenocarcinoma Bronchogenic carcinoma SCC Malignant histiocytosis (Rotties, Goldens, and Bernese) Abscesses (Can’t tell difference from tumor) Granuloma Hematoma Fulid filled cyst or bullae What are the differentials? Structured (Nodules/Masses) Multiple: Metastatic tumors Fungal granulomas Parasitic granulomas (Aleurosyrongylus – Feline lung worm) Abscessation Lymphoma Malignant hystiocytosis Lymphoid granulomatosis Miliary (remember what the seeds look like): Lymphoma Fungal pneumonia Hematogenous bacterial pneumonia Metastatic thyroid, haemangiosarcoma or mammary carcinoma What are the differentials? Unstructured Artifact (MOST COMMON) Underexposure/development: film too “light” Expiratory radiograph Obese animals Forelimbs not pulled forward (musculature in way) Age: lungs less elastic (scarring) Pneumonia (cells) Bacterial (MOST COMMON) right middle lung lobe Fungal: common blasto, crypto, histio, coccidiomycoses Viral: distemper – caudodorsal distribution What are the differentials? Unstructured Cardiogenic edema (fluid): precedes alveolar pattern Non-cardiogenic edema: usually caudodorsal Near drowning Epilespy, seizure Electric cord bite Head trauma Hemorrhage/contusions: DIC, anticoagulant poisoning Neoplasia: Lymphoma, metastatic (hemangio/adenocarcinoma) Allergic Parasitic: Heartworm or lungworms What do they look like? Alveolar pattern: Alveoli are filled with blood, pus, edema, etc. Stuff in the inner garbage bag!!!!! Air bronchograms – just b/c they’re not there doesn’t mean it’s not alveolar (hard to see in cats) Lobar sign – alveolar pattern extends to the border of normal lung lobe Difficult to see heart margins, diaphragm, bronchial walls, or pulmonary vasculature. What are differentials? Consolidation (alveoli infiltrated) Pneumonia Aspiration usually right middle Bronchopneumonia usually cranioventral Edema (Caudal lung lobes in dog, variable in cat) Cardiogenic – LHF Non-Cardiogenic – upper airway obstruction (including brachycephalics and lar. Par), electrocution, seizures, allergic, near drowning and blood transfusions. Hemorrhage – usually asymmetrical Neoplasia Atelectasis (alveoli collapsed): look for mediastinal shift towards affected lung, only see bronchograms with moderate to severe collapse Anesthesia Pleural effusion Pneumothorax Asthma Lung lobe torsion – usually right middle lung lobe Remember Dr. Ps ABCs A = Atelectasis, Anesthesia B = Bronchopneumonia, Bacterial pneumonia C = Contusion, Cancer D = Dirofilaria E = Edema (Cardiogenic and Non) F = Bronchial Foreign Body (caudal lobes) G = Granulomatous (Fungal) H = Hemorrhage What can I do to diagnose it further? History & PE big help Signalment, Trauma, anesthesia, previously dx heart dz or murmur ausculted? Diuretic – If it is edema you will see significant change if you re-radiograph in ~ 12 hours. If it is hemorrhage or bronchopneumonia will see no change TTW or BAL – determine what type of fluid and culture for possible bronchopneumonia What do they look like? Bronchial Pattern: Increased visibility of the bronchial wall due to thickening or mineralization. May see change in size and shape of the lumen. Stuff along the wall of the white balloon. Donuts (end on) Railroad tracks (longitudinal) What are differentials? Bronchial Mineralization AGE: Insignificant in older and chondrodystrophic dogs Calcification of peribronchial mucus glands in cats Hyperadrenocorticism or long term corticosteroid use Bronchial Thickening Chronic bronchitis: older animals Feline asthma PIE – Pulmonary Infiltrate with eosinophilia Parasites (aelurostrongylosis) Neoplasia: Lymphoma, bronchogenic adenocarcinoma What can I do to diagnose it further? TTW or BAL Cytology to determine what type of cells are present (eosinophils, neoplastic?) What do they look like? Mixed: Variable – depends on what process is dominating Bronchointerstitial pattern most common Alveolar and interstitial patterns are sometimes hard to evaluate and often co-exist