CASE STUDY Karen Fitzmaurice Urology Cancer Coordinator Tallaght Hospital Presentation • 25 yr old single man • No PMX of note • Sept 2012 generally unwell • Weight loss • Fever • Night sweats • Seen by GP • CT – large retroperitoneal mass 15 x 12 x 11cms • Referred to Oncology Presentation • Tumour Markers • AFP – 1.0 (0 - 5.0) • HCG – 6.2 (<5 ) • LDH – 2475 (100 - 350) • Testicular exam - NAD • Bx. of mass – extra gonadal germ cell tumour – embryonal carcinoma. • Sperm banking attempted - no sperm seen Treatment • 4 cycles EP (Etoposide & Cysplatin) • Complicated by intrahepatic thrombosis of the IVC • Commenced Clexane • CT - mass reduced in size to 5.2 x 4.2 x 3.7 cms • Referred to Mr Thornhill Surgery • Extensive RPLND on 24/05/2013 mass was densely adherent and required an arterial graft from aorta to the right iliac artery. • Operating time 8 ½ hours • EBL= 3,600mls • Developed right leg ischemia in the recovery room & returned to theatre Exploration of graft with popliteal & pedal embolectomy • Significant amount of thrombus recovered • Transferred to ICU 1ST Day Post Op • Developed right leg pain & reduced ankle movement. • Possible compartment syndrome (increased pressure within a muscle compartment) • Patients are at higher risk of compartment syndrome when a blood vessel is damaged & subsequently repaired through surgery. Right Calf Fasciotomy Closure of medial fasciotomy & VAC dressing to lateral fasciotomy 27/05/13 Post Operative care • MDT – nursing & medical staff, dietician, physiotherapy, Pain team, occupational health, discharge planning. • PCEA • TPN • NPO, N/G, central line • U/C • Clips & tension sutures • Heparin x 7 days then clexane • 6/7 ICU • Weight bear 3/7 post op • Exercises - prevent foot drop • Resting calf splint • Mobilising frame 2/52 post op. • Vac dressing x 15 days • Occupational health home visit • Discharged on 12/06/13 Discharge • Convalescence x 1/52 • Community physiotherapy • 24/07/13 seen in clinic for histology results – no evidence of residual viable tumour. • D/C from urology to oncology. • October 2013 – resumed normal activity i.e. swimming & cycling. • Continues to attend physiotherapy sessions.