WHAT’S THE LATEST IN DIABETES & FOOT CARE? Axel Rohrmann Podiatrist diabetes.ca | 1-800-BANTING (226-8464) The time to act is NOW! 1 2 3 KEY MESSAGE Foot problems are a major cause of morbidity & mortality in people with diabetes. • Management of foot ulceration requires an interdisciplinary approach (glycaemic control, infection, vascular status, foot wear & wound care). • Uncontrolled diabetes may result in immunopathy with a blunted cellular response to foot infection. • INTRODUCTION • Diabetes is a serious chronic disease. – – • 20% of diabetic hospitalizations are foot related. – • prevalence estimated at 246 million globally in 2007. 4th leading cause of death in most developed countries. 70% of all leg amputations happen to people living with diabetes. (> 1 million / year or 1 every 30 seconds). Foot ulcers precede the majority of amputations. – In developed countries 1 in 6 diabetics will have an ulcer Limb Loss Prognosis with Diabetes 2% of all persons with diabetes will need an amputation. 5496 amputations last year! 50% of amputees will lose the other limb in 3 to 5 years. Up to 50% mortality five years after first amputation. The situation can be changed Possible to reduce amputation rates between 49% & 85%. Care strategy: Prevention Multi-disciplinary treatment Appropriate organization of care Close monitoring Education (people with diabetes & health care professionals) Diabetes is a biochemical disease • “Diabetes mellitus is a biochemical disease, but a large number of lower extremity complications of the disorder are due to biomechanical dysfunction.” (Source: Payne, 1998.) • Diabetics may have altered biomechanics; or • Present with a complication of any pre-existing neurovascular or biomechanical dysfunction. Risk Factors for Ulceration Social / cultural habits Mobility Deformities Vascular status Neurological status Skin lesions: ulcers, callus, blisters Footwear Compliance & understanding Risk Identification & Categories Will risk identification & categorization reduce the number of: Primary ulcerations? Re-ulcerations? Amputations? 9 Foot Ulceration • Approximately 85% of diabetes-related amputations start off with a foot ulcer that deteriorates, becomes infected & gangrenous! Most foot ulceration CAN be avoided /prevented The “At-Risk” Foot 2 types of risk: 1. At risk for ulceration 1. At risk for limb loss Risk Factors for Ulceration • • Peripheral neuropathy – Sensory – Autonomic – Motor Risk factors for neuropathy include High levels of glycaemia, elevated triglycerides, high BM smoking & hypertension. 13 Risk Factors for Ulceration Sensory Neuropathy • Largest single risk factor for diabetic foot ulcers Burning, tingling, ”pins & needles”, numbness or “dead” feeling – Repeated unrecognized stress, pressure, friction & shearing. – Lack sensation to feel foreign objects, heat changes, discomfort or pain. – 14 Risk Factors for Ulceration Autonomic Neuropathy • • Impairs skin integrity, sweat regulation & blood flow. Leads to: – – thick, dry cracked skin, fissures callus build-up at pressure points Risk Factors for Ulceration Motor Neuropathy • • • • Loss of muscle tone in the foot Foot deformities: – Hammer toes – Claw toes Metatarsal heads become prominent Changes in pressure distribution & gait pattern Photo used with permission from Dr.Axel Rohrmann, Podiatrist. Risk Factors for Ulceration Under diagnosis of neuropathy • • Fundamental problem in primary care. Impedes early identification, management & prevention of squeals . Risk Factors for Ulceration • • • • Elevated Pressures & Foot Deformity Pes Planus - flat foot Pes Cavus- high arch Charcot Foot- (significant disruption of the bony architecture) Lesser toe deformities Note also • Prayer sign - hands • Occur in presence of: peripheral sensory neuropathy, autonomic neuropathy and trauma. • Presentation: painless, unilateral oedema, erythema, with or without foot deformity, bounding pedal pulses. Post tib dysfunction in later stages. Photo used with permission from Dr.Axel Rohrmann, Podiatrist. CHARCOT FOOT Diabetic Neuropathic Osteoarthropathy • • • Occur in presence of peripheral sensory neuropathy, autonomic neuropathy & trauma. Presentation: painless, unilateral oedema, erythema, with or without foot deformity, bounding pedal pulses. Post tibial dysfunction in later stages. Note: – – – – Acute charcot can mimic cellulitis & DVT Radiological findings can be normal at first Strict immobilization of foot for management Patient education, protective footwear to prevent ulcerations Risk Factors for Ulceration Calluses • • • • • Presence of callus in an insensitive foot is highly predictive of subsequent foot ulceration. Breakdown of underlying tissues Regular debridement Pressure relief : insoles / moulded orthotics Footwear Calluses increase pressure on underlying tissue by 30% Photo used with permission from Axel Rohrmann, Podiatrist. Risk Factors for Ulceration Limited Joint Mobility – – – – Hallux rigidus Hallux limitus Hammer toes Claw toes Limited joint mobility can cause increased ground reaction forces under weight-bearing joints. This can lead to ulceration. Photo used with permission from Dr. Axel Rohrmann, Podiatrist. Risk Factors for Ulceration Previous Ulceration & Amputation Skin texture • Scar tissue reduced tensile strength. • Pressure points • NEUROVASCULAR ASSESSMENT Type 1 – 5 years post diagnosis. Type 2 - When diagnosed & annually or as indicated by risk category. diabetes.ca | 1-800-BANTING (226-8464) What to look for & assess! Dermatological: – – – – – – – – – – Color Temperature Texture Errythema Edema Lesions Fissures Callus Ulcers Nail disorders Vascular: Pedal pulses digital hair capillary revascularization – Varicosities – ABI, TPI, PPG – Edema – Transcutaneous oxygen concentrations – Angiography – MRI – – – What to look for & assess! Neurological: – – – – 10g Monofilaments Reflexes Vibration perception Proprioception Biomechanical: – – – – – – Gait Joint mobility Anomalies & limitations Amputations Foot wear Hosiery DIABETIC FOOT ULCERS Diagnose the aetiology!!!! – neurovascular, biomechanical, trauma diabetes.ca | 1-800-BANTING (226-8464) Healing the wound Diabetic wound healing is a complicated process that requires a definite plan based on scientific fact. A validated classification system can be the roadmap to get you there. University of Texas wound classification This straightforward system grades wounds first with numbers 0 to 3 referring to depth: – – – – 0 1 2 3 (pre- or post-ulcer with epithelialization), (superficial and not involving tendon, bone or capsule), (ulcer penetrates through to tendon or capsule), and (penetrating to bone or joint). A second classification tier, A to D, refers to other burdens on the wound. – – – – A indicates non-infected/non-ischemic, B indicates infection, C indicates ischemia, and D indicates infection plus ischemia. Evaluation & Management of Infection in DM Foot • • Assess whether or not infection is present. If present determine the depth & the nature of involvement (e.g. whether OM or un-drained pus is present). Evaluation & Management of Infection in DM Foot • • Surgically debride all devitalised tissue, repeatedly if necessary. Obtain adequate & appropriate material for culture of aerobic & anaerobic organism. Evaluation & Management of Infection in DM Foot • • Ensure that the patient with plantar or heel ulceration complies with strict non-weight bearing until complete healing has occurred. Modify risk factors for future infection whenever possible (e.g. foot deformity, improper footwear, poorly educated patient) Evaluation & Management of Infection in DM Foot Control hyperglycaemia* & other metabolic derangement *Rayfield EJ, Ault MJ, Keusch GT, Brothers MS, Nechemias C, Smith H. Infection and diabetes: the case for glucose control. AM J Med 1982;72:439-450 Evaluation & Management of Infection in DM Foot Empiric anti-microbial treatment active against most commonly isolated pathogens and/or those seen on initial Gram’s stain. • Modify regimen based on culture results. • Ensure adequate vascular supply exist. • Follow up prevention • • • • • • Daily home foot examination by person with diabetes and/or care provider. Frequent visits to appropriate team member(s) to evaluate feet & shoes. Education of patient, family & healthcare providers. Appropriate footwear. Treatment of non-ulcerative pathology. TLC! You Can Make a Difference Awareness & intervention can prevent many problems with the diabetic foot. diabetes.ca | 1-800-BANTING (226-8464) New website diabetes.ca Thank you! diabetes.ca | 1-800-BANTING (226-8464) References