Extending prosthesis longevity through tribological understanding James Lord & Dr Tom Joyce Newcastle University CREST Contents • What are hip prostheses? – Types – Metal-on-polyethylene vs. metal-on-metal • Wear • My work – Linear and volumetric wear – Surface characterisation – Analyses of important factors • What’s next? • Questions Newcastle University CREST What are hip prostheses? • Attempts to replace the damaged hip joint with long-lasting biocompatible materials • Reduce pain and restore function • Can be traced back 120 years • Traditionally metal-on-polyethylene articulation • More recent shift to metal-on-metal articulation Newcastle University CREST Types of hip prosthesis • Total hip replacement • Hip resurfacing Newcastle University CREST Metal-on-polyethylene • Charnley – 1960s & 1970s • Survivorship can be around 80% after 20 years • Reported cases of early failures • Failures greater in younger patients – Kim, 2003 • Polyethylene debris linked to osteolysis Newcastle University CREST Metal-on-metal • MoM shown to produce smaller particles and less overall volumetric wear than MoP • Machinability • Generally good short-term results – Treacy et al, 2005 – 98% at 5 years – Khan et al, 2009 – 95.7% at 8 years • Long-term studies less common Newcastle University CREST Metal-on-metal • Still many reported cases of early failure – Fracture – Infection – Metal debris Newcastle University CREST Wear • Bearing surfaces • Many potential factors – Manufacturing – Surgical – Patient • Creates debris – Osteolysis – Metallosis Newcastle University CREST My work • Extending prosthesis longevity through a reduction in wear • Study of 150 retrieved components • Volumetric wear of retrieved components • Wear characterisation • Influencing factors – Manufacturing – Surgical – Patient Newcastle University CREST Volumetric wear • Co-ordinate measuring machine recommended by international standards • Measures 3-dimensional Cartesian co-ordinates • Ruby-tipped contact stylus • 72 line scans ~2000 measured points • Self-centring scans • Some analysis Newcastle University CREST Volumetric wear • Co-ordinate data from CMM Z • Linear wear depths calculated 20 10 0 • Wear volumes calculated – From 0.71 - 134.22mm3 – Wear rates from 0.02 5.77mm3/month Newcastle University 20 10 20 10 0 0 -10 Y -20 -10 -20 X CREST Validation Gravimetric wear Calculated wear volume (mm3) volume (mm3) Difference (%) Unworn 0 0 - 1st volume removal 5.89 5.78 1.87 2nd volume removal 12.09 11.99 0.83 Newcastle University CREST Volumetric wear • Surface coloured according to linear wear depth • Histogram of depths 250 200 150 100 50 0 -0.07 Newcastle University -0.06 -0.05 -0.04 -0.03 -0.02 -0.01 0 0.01 0.02 CREST Surface characterisation • Interferometry - occurs on the nanometre scale • Areas of interest informed by Matlab analysis Wear scar Transition zone Unworn Newcastle University CREST Qualitative characterisation Newcastle University CREST Qualitative characterisation Newcastle University CREST Qualitative characterisation Newcastle University CREST Quantitative characterisation • Unworn surface – Ra: 0.019μm – Rms: 0.039μm • Transition zone – Ra: 0.028μm – Rms: 0.063μm • Wear scar – Ra: 0.200μm – Rms: 0.280μm Newcastle University CREST Analysis – Wear volumes 160 Wear volume / mm 3 140 120 100 80 60 40 20 0 0 20 40 60 80 100 120 Duration / months Newcastle University CREST Analysis – Failure mode 160 Wear volume / mm 3 140 120 100 ARMD Early fracture 80 ARMD fracture 60 40 20 0 0 10 20 30 40 50 60 70 80 90 Implant duration / months Newcastle University CREST Analysis - Manufacturer Wear volume / mm 3 30 25 20 36mm BHR 15 Durom Metasul 10 5 0 0 20 40 60 80 100 120 Duration / months Newcastle University CREST Analysis - Manufacturer 160 Wear volume / mm 3 140 120 36mm 100 ASR BHR 80 Durom 60 Metasul 40 20 0 0 20 40 60 80 100 120 Duration / months Newcastle University CREST Analysis – Implantation angle 250 Volume (mm3) 200 150 100 50 0 0 10 20 30 40 50 60 70 80 90 100 Inclination angle (0) Newcastle University CREST Analysis – In vivo data 300 R2 = 0.9407 200 150 100 50 0 0 50 100 150 200 250 Combined volumetric wear / mm 300 350 3 80 R2 = 0.8906 70 Blood Co ions Blood Cr ions 250 60 50 40 30 20 10 0 0 50 100 150 200 250 300 350 Combined volumetric wear / mm3 Newcastle University CREST Analysis • Wear volumes/rates – – – – Failure modes Different manufacturers Implantation angle Correlation to in vivo data • Roughness values – Low/high wear samples – Self-polishing • Tribology – Lubrication regime Newcastle University CREST What’s next? • Data collection – Full data sets for current samples – New samples • Statistical analysis – Significant factors affecting wear – Roughness values • Other prostheses Newcastle University CREST Questions? Newcastle University CREST