CHAPTER 5

Integumentary System

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Integumentary System

• Skin

– Also called integument or cutaneous membrane

– Epidermis

– Dermis

– Subcutaneous layer

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Integumentary System

• Accessory structures

– Hair

– Nails

– Glands

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Layers and Structures of the Skin

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Structure of the Nail

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Question

True or False: The epidermal layer contains most of the skin's vital structures.

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Question

The half-moon we see at the base of our fingernails is called the _______.

a. cuticle b. lunula c. nail bed d. edge

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Skin Lesions

• Abrasion

– Scraping or rubbing away of skin or mucous membrane as a result of friction to the area

• Example: carpet burn

• Abscess

– Localized collection of pus in any body part that results from invasion of pus-forming bacteria

• Example: pustule = small abscess

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Skin Lesions

• Blister

– Small, thin-walled lesion containing clear fluid

– Also known as a vesicle

• Bulla

– Large blister

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Skin Lesions

• Carbuncle

– Circumscribed inflammation of skin and deeper tissues; contains pus

• Comedo

– Typical lesion of acne vulgaris

• Example: whitehead = closed comedo

• Example: blackhead = open comedo

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Skin Lesions

• Cyst

– Closed sac or pouch in or within the skin; contains fluid, semifluid, or solid material

• Example: hydrocele = fluid-filled cyst

• Example: sebaceous cyst = solid-filled cyst

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Skin Lesions

• Fissure

– Crack-like sore or groove in the skin or mucous membrane

• Example: anal fissure

• Fistula

– Abnormal passageway between two tubular organs, or from an organ to the body surface

• Example: rectovaginal fistula

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Skin Lesions

• Hives

– Circumscribed, slightly elevated lesions on skin; paler in center than surrounding edges

– Also called wheals

• Example: mosquito bite

• Laceration

– Tear in skin; torn, jagged wound

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Skin Lesions

• Macule

– Small, flat discoloration of the skin; neither raised nor depressed

• Example: bruises, freckles

• Nodule

– Small, circumscribed swelling protruding above the skin

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Skin Lesions

• Papule

– Small, solid, circumscribed elevation on the skin

• Example: pimple, wart, elevated mole

• Polyp

– Small, stalk-like growth, protruding upward or outward from membrane surface

• Example: nasal polyp

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Skin Lesions

• Pustule

– Small elevation of skin filled with pus

• Example: small abscess on the skin

• Scales

– Thin flakes of hardened epithelium that are shed from the epidermis

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Skin Lesions

• Ulcer

– Circumscribed, open sore or lesion of skin, accompanied by inflammation

• Example: decubitus ulcer

• Vesicle

– Small, thin-walled lesion containing clear fluid

• Example: blister

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Skin Lesions

• Wheal

– Circumscribed, slightly elevated lesion of the skin

– Paler in center than surrounding edges

• Example: hives

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Question

Notice that sometimes 2 different terms are used to describe the same thing. For instance, if a physician says a patient has hives, this patient also has: a. comedos b. papules c. cysts d. wheals

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Question

A patient has a rash consisting of both macules and papules. What would be the combined adjective form?

a. maculepapular b. papulemacular c. papulomacular d. maculopapular e. c and d

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Acne Vulgaris

• Pronounced

– (

ACK -nee vulGAY -ris)

• Defined

– Common inflammatory disorder seen on face, chest, back, and neck

– Appears as papules, pustules, and comedos

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Albinism

• Pronounced

– (

AL -bin-izm)

• Defined

– Condition characterized by absence of pigment in the skin, hair, and eyes

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Burns

• Defined

– Tissue injury produced by flame, heat, chemicals, radiation, electricity, or gases

– Extent of damage determined by:

• Mode and duration of exposure

• Thermal intensity or temperature

• Anatomic site of the burn

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Burns

• First-degree (superficial) burns

– Example: sunburn

• Second-degree (partial-thickness) burns

– Example: flash contact with hot objects

• Third-degree (full-thickness) burns

– Example: deep burns from a fire

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Callus

• Pronounced

– (

CAL -us)

• Defined

– Common, usually painless thickening of the epidermis at sites of external pressure or friction, such as weightbearing areas of the feet and on the palmar surface of the hands

– Also known as a callosity

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Question

True or False: The higher the degree rating, the deeper the burn.

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Carcinoma, Basal Cell

• Pronounced

– ( car -sihNOH -mah BAY -sal sell)

• Defined

– A malignant epithelial cell tumor

– Begins as a slightly elevated nodule with a depression or ulceration in the center

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Carcinoma, Basal Cell

• Defined

– As the depression enlarges, the tissue breaks down, crusts, and bleeds

– Most common malignant tumor of epithelial tissue; occurs most often on skin exposed to the sun

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Carcinoma, Basal Cell

• Image courtesy of Robert A. Silverman,

M.D., Pediatric Dermatology, Georgetown

University

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Carcinoma, Squamous Cell

• Pronounced

– ( car -sihNOH -mah SKWAY -mus sell )

• Defined

– Malignancy of the squamous, or scale-like, cells of the epithelial tissue

– Much faster growing than basal cell carcinoma

– Greater potential for metastasis if not treated

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Carcinoma, Squamous Cell

• Frequent sites on sun-exposed areas

– Top of nose

– Forehead

– Margin of external ear

– Back of hands

– Lower lip

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Question

True or False: Basal cell carcinoma does not originate in the epithelial layer.

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Dermatitis

• Pronounced

– (der-mah-

TYE -tis)

• Defined

– Inflammation of skin, seen in several different forms

– Acute or chronic

– Contact or seborrheic

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Eczema

• Pronounced

– (

EK -zeh-mah)

• Defined

– Acute or chronic inflammatory skin condition characterized by erythema, papules, vesicles, pustules, scales, crusts, scabs, and itching

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Exanthematous Viral Diseases

• Pronounced

– ( eks -anTHEM -ah-tus VYE -ral dihZEEZ -ez)

• Defined

– Skin eruption or rash accompanied by inflammation, having specific diagnostic features of an infectious viral disease

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Exanthematous Viral Diseases

• Examples

– Rubella = German measles = 3-day measles

– Roseola infantum

– Rubeola = red measles = 7- to 10-day measles

– Erythema infectiosum = fifth disease

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Gangrene

• Pronounced

– (

GANG -green)

• Defined

– Tissue death due to loss of adequate blood supply, invasion of bacteria; subsequent decay with foul odor

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Herpes Zoster

• Pronounced

– (

HER -peez ZOS -ter)

• Defined

– Acute viral infection, characterized by painful, vesicular eruptions on the skin that follow along nerve pathways of underlying spinal or cranial nerves

– Highest incidence in adults over 50

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Herpes Zoster

Image courtesy of Robert A. Silverman,

M.D., Pediatric Dermatology,

Georgetown University

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Impetigo

• Pronounced

– (im-peh-

TYE -goh)

• Defined

– Contagious superficial skin infection characterized by serous vesicles and pustules filled with millions of staphylococcus or streptococcus bacteria

• Usually forming on the face

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Question

This viral infection is derived from a childhood disease, and then it most commonly flares up after age 50 along nerve pathways: a. eczema b. rubeola c. Herpes zoster d. impetigo

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Kaposi’s Sarcoma

• Pronounced

– (

KAP -oh-seez sarKOH -ma)

• Defined

– Rare malignant lesions beginning as soft purple-brown nodules or plaques on the feet

– Gradually spreads throughout skin

– Increased incidence in men with AIDS

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Keloid

• Pronounced

– (

KEE -loyd)

• Defined

– Enlarged, irregularly shaped, elevated scar that forms due to the presence of large amounts of collagen during formation of a scar

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Keratosis

• Pronounced

– (kair-ah-

TOH -sis)

• Defined

– Skin condition in which there is a thickening and overgrowth of the cornified epithelium

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Seborrheic Keratosis

• Pronounced

– (seb-oh-

REE -ik kair-ahTOH -sis)

• Defined

– Brown or waxy yellow, wart-like lesions that are loosely attached to the skin

– Also known as senile warts

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Actinic Keratosis

• Pronounced

– (ak-

TIN -ic kair-ahTOH -sis)

• Defined

– Premalignant, gray or red-to-brown, hardened lesion caused by excessive exposure to sunlight

– Also known as solar keratosis

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Leukoplakia

• Pronounced

– (loo-koh-

PLAY -kee-ah)

• Defined

– White, hard, thickened patches firmly attached to the mucous membrane

• In mouth, vulva, or penis

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Question

True or False: Keratosis literally means condition of a horny-like growth in the upper layer of skin, like a wart or callus.

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Malignant Melanoma

• Pronounced

– (mah-

LIG -nant mel-ahNOH -mah)

• Defined

– Malignant skin tumor originating from melanocytes in preexisting nevi, freckles, or skin with pigment

– Darkly pigmented tumor with irregular surfaces and borders; variable colors

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ABCDs of Malignant Melanomas

A symmetry

B orders

C olor

D iameter

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Nevus

• Pronounced

– (

NEV -us)

• Defined

– Visual accumulation of melanocytes, creating a flat or raised rounded macule or papule with definite borders

– Commonly known as a mole

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Question

Based on the definition of melanoma, what is the actual meaning of melan-?

a. dark pigment b. light pigment c. blue pigment d. white pigment

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Onychocryptosis

• Pronounced

– ( on -ih-koh-kripTOH -sis)

• Defined

– Ingrown nail

• Most commonly involves the large toe

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Onychomycosis

• Pronounced

– ( on -ih-koh-myKOH -sis)

• Defined

– Fungal infection of the nails

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Pediculosis

• Pronounced

– (peedik -youLOH -sis)

• Defined

– Highly contagious parasitic infestation caused by bloodsucking lice

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Pediculosis

• Pediculosis capitis

– Head

• Pediculosis corporis

– Body

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Pediculosis

• Pediculosis palpebrarum

– Eyelashes and eyelids

• Pediculosis pubis

– Pubic hair

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Pemphigus

• Pronounced

– (

PEM -fih-gus)

• Defined

– Rare, incurable disorder manifested by blisters in the mouth and on the skin

– Spreads to involve large areas of the body

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Pilonidal Cyst

• Pronounced

– ( pye -lohNYE -dal SIST )

• Defined

– Closed sac located in the sacrococcygeal area of the back

– Sometimes noted at birth as a dimple

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Psoriasis

• Pronounced

– (soh-

RYE -ah-sis)

• Defined

– Common, noninfectious, chronic skin disorder manifested by silvery-white scales over round, raised, reddened plaques producing itching

– Pruritus

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Psoriasis

• Image courtesy of Robert A. Silverman,

M.D., Pediatric Dermatology, Georgetown

University

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Question

True or False: Pilus means hair and nidus means nest; therefore, a pilonidal cyst probably literally means a fluid “nest” containing hair.

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Rosacea

• Pronounced

– (roh-

ZAY -she-ah)

• Defined

– Chronic inflammatory skin disease that mainly affects the skin of the middle third of the face

– Characterized by persistent redness over areas of the face, nose, and cheeks

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Scabies

• Pronounced

– (

SKAY -beez)

• Defined

– Highly contagious parasitic infestation caused by the

“human itch mite”

– Resulting in a rash, pruritus, and a feeling in the skin of

“something crawling”

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Scleroderma

• Pronounced

– ( sklair -ohDER -mah)

• Defined

– Gradual thickening of the dermis and swelling of the hands and feet to a state in which the skin is anchored to the underlying tissue

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Systemic Lupus Erythematosus

• Pronounced

– (sis-

TEM -ic LOO -pus air -ih-them-ahTOH -sus)

• Defined

– Chronic, multisystem inflammatory disease characterized by lesions of the nervous system and skin, renal problems, and vasculitis

– Characteristic “butterfly rash” is often seen on nose and face

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Tinea

• Pronounced

– (

TIN -ee-ah)

• Defined

– Chronic fungal infection of the skin

– Characterized by scaling, itching, and sometimes painful lesions

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• Tinea capitis

– Scalp

• Tinea corporis

– Body

Tinea

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• Tinea cruris

– Groin

• Tinea pedis

– Foot

Tinea

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Verruca

• Pronounced

– (ver-

ROO -kah)

• Defined

– Benign, circumscribed, elevated skin lesion that results from hypertrophy of the epidermis

– Commonly known as a wart

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Verruca

• Verruca vulgaris

– Common wart on face, elbow, fingers, or hands

• Plantar warts

– Singly or in clusters on the sole of the foot

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Verruca

• Venereal warts

– Transmitted by sexual contact

• Seborrheic warts

– Seen in the elderly on the face, neck, chest, or upper back

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Question

When people say they can feel their skin crawl, perhaps they have this condition where a tiny bug is the culprit?

a. verruca vulgaris b. dermatitis c. scabies d. rosacea

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Diagnostic Techniques, Treatments, and Procedures

• Allergy testing

– Various procedures used to identify specific allergens in an individual by exposing the person to a very small quantity of the allergen

• ImmunoCAP Allergy Blood Test more advanced, convenient, and reliable

• Cautery

– Heat or caustic substances that burn and scar the skin

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Diagnostic Techniques, Treatments,

• Cryosurgery and Procedures

– Noninvasive treatment that uses subfreezing temperature to freeze and destroy tissue

• Curettage and electrodesiccation

– Scraping away of abnormal tissue, followed by destroying the tumor base with a low-voltage electrode

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Diagnostic Techniques, Treatments,

• Debridement and Procedures

– Removal of debris, foreign objects, and damaged or necrotic tissue from a wound in order to prevent infection and promote healing

• Dermabrasion

– Removal of the epidermis and a portion of the dermis with sandpaper or brushes in order to eliminate superficial scars of unwanted tattoos

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Diagnostic Techniques, Treatments, and Procedures

• Dermatoplasty

– Skin transplantation to a body surface damaged by injury or disease

• Electrodesiccation

– Technique using an electrical spark to burn and destroy tissue

– Also known as fulguration

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Diagnostic Techniques, Treatments, and Procedures

• Electrosurgery

– Removal or destruction of tissue with an electrical current

• Escharotomy

– Incision made into the necrotic tissue resulting from a severe burn

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Diagnostic Techniques, Treatments,

• Liposuction and Procedures

– Aspiration of fat through a suction cannula or curette to alter the body contours

• Skin biopsy

– Removal of a small piece of tissue from skin lesions for examination under a microscope to confirm or establish a diagnosis

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Diagnostic Techniques, Treatments, and Procedures

• Skin graft

– Process of placing tissue on a recipient site, taken from a donor site, in order to provide the protective mechanisms of skin to an area unable to regenerate skin

• Wood’s lamp

– Ultraviolet light that is used to examine the scalp and skin for the purpose of observing fungal spores

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Question

True or False: A person with third-degree burns would benefit from a dermatoplasty.

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