Management of Iliac Aneurysms

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Management of Iliac

Artery Aneurysms

Etiology

Idiopathic – Remote collagen vascular disease

Atherosclerosis, Smoking

Infectious (TB, Syphilis, S. aureus, Salmonella,

Klebsiella)

Collagen diseases (Marfan’s, Ehlers-Danlos,

Cystic Medial Necrosis)

Takayasu’s, Kawasaki’s, Bechet’s, etc.

Incidence

0.03% lifetime incidence

0.3-1.9% of arterial aneurysms

75-95% present with AAA

7th-8th decade of life

8-9:1 male:female ratio

Common Iliac Artery - 70%

Internal Iliac Artery - 20%

External Iliac Artery - 10%

Bilateral Disease – 20-60%

Complications

Rupture

Distal embolization

Thrombosis

Urologic symptoms secondary to ureteral compression

Pain from compression of adjacent nerves and vicera (Rare)

Complications

106 Patients

59 presented with intact IAA (mean 3.9cm)

10 presented with rupture (mean 7.2cm)

37 unoperated on (mean 3.2cm)

12 enlarged

3 ruptured (smallest 3.5cm)

Kasirajan V et al. Card Surg. 1998: 6(2), 171-177.

Natural History

Santilli et al, 2000 (U. of Minnesota)

189 patients in VA system (2 women) with 323 iliac artery aneurysms

47 patients with isolated IAA

Followed with USG or CT at 6 month intervals

Average f/u: 31.4 months (4.2 studies)

Survival: 96.3% at 1 year, 88.5% at 2 years, 72.3% at

3 and 4 years

Natural History

Average rate of expansion: 0.118 +/- 0.017 cm/year

No expansion in 37.5%

All IAA between 4 and 4.9cm expanded (All

>5cm repaired)

<3cm: 0.05-0.15cm/year

>3cm: 0.25-0.28cm/year

Natural History

Santelli et al. J Vasc Surg. 2000: 31(1), 114-121

Surgical Intervention

All series >/= 5 patients between 1961 and 1997

367 patients with 500 IIAs

Mean age 68 years

Symptomatic: 208 (62%)

Asymptomatic: 123 (38%)

Rupture: 108 (29%)

Emergent mortality: 40%

Elective mortality: 7%

Krupski et al, J Vasc Surg. 1998: 28(1)

Surgical Intervention

Krupski et al, 1998 (U. of Colorado)

21 patients (17 men, 4 women)

Mean age 69 years (38-87)

52% unilateral disease, 57% symptomatic

Aneurysm >2.5cm (2.5-12cm, mean 5.6 +/- 2cm)

Smoking 71%, HTN 67%, CAD 52%, Prior CABG 19%

Mean follow up 5.5 years (2 months - 13 years)

Surgical Intervention

Krupski et al.

19 open repairs, 0 perioperative deaths

17 Elective

1 - Right LE compartment syndrome

2 Emergent

1 - C. diff requiring colectomy

1 - Multisystem Organ Failure due to rupture/shock

Surgical Intervention

Krupski et al.

2 Endovascular repairs

1 - required femorofemoral bypass due to stent occlusion

1 - died from rupture 2 years post coiling

Conclusions

Rupture under 3cm very rare

High risk of rupture for aneurysms greater than 5cm with a correlation between increasing size and increasing risk of rupture

Many aneurysms remain stable - safe to monitor patients yearly with aneurysms <3cm and every 6 months 3-3.5cm

Surgical risk for otherwise uncomplicated patients now generally very low

Further need for long term comparison of open vs. endovascular repair

References

Santilli SM, Wernsing SE, Lee ES. Expantion rates and outcomes for iliac artery aneurysms.

Journal of Vascular Surgery. 2000: 31(1), 114-121.

Kasirajan V et al. Management of isolated common iliac artery aneurysms. Cardiovascular Surgery.

1998: 6(2), 171-177.

Dorigo W et al. The Treatment of Isolated Iliac Artery Aneurysm in Patients with Nonaneurysmal Aorta. European Journal of Vascular and Endovascular Surgery. 2008, doi:10.1016/j.ejvs.2007.11.017.

Krupski WC et al. Contemporary management of isolated iliac aneurysms. Journal of Vascular

Surgery. 1998: 28(1).

Brunkwall J et al. Solitary aneurysms of the iliac artery system: an estimate of their frequency and occurance. Journal of Vascular Surgery. 1989:10, 381-384.

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