Idiopathic – Remote collagen vascular disease
Atherosclerosis, Smoking
Infectious (TB, Syphilis, S. aureus, Salmonella,
Klebsiella)
Collagen diseases (Marfan’s, Ehlers-Danlos,
Cystic Medial Necrosis)
Takayasu’s, Kawasaki’s, Bechet’s, etc.
0.03% lifetime incidence
0.3-1.9% of arterial aneurysms
75-95% present with AAA
7th-8th decade of life
8-9:1 male:female ratio
Common Iliac Artery - 70%
Internal Iliac Artery - 20%
External Iliac Artery - 10%
Bilateral Disease – 20-60%
Rupture
Distal embolization
Thrombosis
Urologic symptoms secondary to ureteral compression
Pain from compression of adjacent nerves and vicera (Rare)
106 Patients
59 presented with intact IAA (mean 3.9cm)
10 presented with rupture (mean 7.2cm)
37 unoperated on (mean 3.2cm)
12 enlarged
3 ruptured (smallest 3.5cm)
Kasirajan V et al. Card Surg. 1998: 6(2), 171-177.
Santilli et al, 2000 (U. of Minnesota)
189 patients in VA system (2 women) with 323 iliac artery aneurysms
47 patients with isolated IAA
Followed with USG or CT at 6 month intervals
Average f/u: 31.4 months (4.2 studies)
Survival: 96.3% at 1 year, 88.5% at 2 years, 72.3% at
3 and 4 years
Average rate of expansion: 0.118 +/- 0.017 cm/year
No expansion in 37.5%
All IAA between 4 and 4.9cm expanded (All
>5cm repaired)
<3cm: 0.05-0.15cm/year
>3cm: 0.25-0.28cm/year
Santelli et al. J Vasc Surg. 2000: 31(1), 114-121
All series >/= 5 patients between 1961 and 1997
367 patients with 500 IIAs
Mean age 68 years
Symptomatic: 208 (62%)
Asymptomatic: 123 (38%)
Rupture: 108 (29%)
Emergent mortality: 40%
Elective mortality: 7%
Krupski et al, J Vasc Surg. 1998: 28(1)
Krupski et al, 1998 (U. of Colorado)
21 patients (17 men, 4 women)
Mean age 69 years (38-87)
52% unilateral disease, 57% symptomatic
Aneurysm >2.5cm (2.5-12cm, mean 5.6 +/- 2cm)
Smoking 71%, HTN 67%, CAD 52%, Prior CABG 19%
Mean follow up 5.5 years (2 months - 13 years)
Krupski et al.
19 open repairs, 0 perioperative deaths
17 Elective
1 - Right LE compartment syndrome
2 Emergent
1 - C. diff requiring colectomy
1 - Multisystem Organ Failure due to rupture/shock
Krupski et al.
2 Endovascular repairs
1 - required femorofemoral bypass due to stent occlusion
1 - died from rupture 2 years post coiling
Rupture under 3cm very rare
High risk of rupture for aneurysms greater than 5cm with a correlation between increasing size and increasing risk of rupture
Many aneurysms remain stable - safe to monitor patients yearly with aneurysms <3cm and every 6 months 3-3.5cm
Surgical risk for otherwise uncomplicated patients now generally very low
Further need for long term comparison of open vs. endovascular repair
Santilli SM, Wernsing SE, Lee ES. Expantion rates and outcomes for iliac artery aneurysms.
Journal of Vascular Surgery. 2000: 31(1), 114-121.
Kasirajan V et al. Management of isolated common iliac artery aneurysms. Cardiovascular Surgery.
1998: 6(2), 171-177.
Dorigo W et al. The Treatment of Isolated Iliac Artery Aneurysm in Patients with Nonaneurysmal Aorta. European Journal of Vascular and Endovascular Surgery. 2008, doi:10.1016/j.ejvs.2007.11.017.
Krupski WC et al. Contemporary management of isolated iliac aneurysms. Journal of Vascular
Surgery. 1998: 28(1).
Brunkwall J et al. Solitary aneurysms of the iliac artery system: an estimate of their frequency and occurance. Journal of Vascular Surgery. 1989:10, 381-384.